Archives of Clinical and Medical Microbiology最新文献_第2页

Biodegradation of Polybrominated Diphenyl Ethers: A Minireview 多溴联苯醚的生物降解研究进展

Archives of Clinical and Medical Microbiology Pub Date : 2022-12-07 DOI: 10.33140/acmmj.01.01.05

Mini Review Article, Mehak Puri

{"title":"Biodegradation of Polybrominated Diphenyl Ethers: A Minireview","authors":"Mini Review Article, Mehak Puri","doi":"10.33140/acmmj.01.01.05","DOIUrl":"https://doi.org/10.33140/acmmj.01.01.05","url":null,"abstract":"Polybrominated diphenyl ethers (PBDEs) are commonly regarded as the Persistent Organic Pollutant (POP). PBDEs are ubiquitous, flame retardants widely found in synthetic polymers, clothing, plastics. PBDEs are threat to the safety of environment and health. Many reclamation studies such as biotransformation, remediation, and neutralisation are reported by chemical and biological processes. Out of the all the biological stood out due to its environmental-friendly and less production or formation of more potent daughter compounds than the parent. Bacterial species such as Pseudomonas, are majorly involved in eradication/removal of the environmental contaminant. The current study highlights the need to use consortium of the microbial species than a single strain and to increase its efficiency one can focus on involving inter-species (bacteria-fungus, bacteria-algae, fungus-algae) and concentrate on the enzymes released for the reductive-oxidative debromination of the PBDEs. The need is to centre the determination of the PBDEs in India and use indigenous organisms for the removal studies targeting the Indian scenario of the PBDEs production, consumption and release.","PeriodicalId":221473,"journal":{"name":"Archives of Clinical and Medical Microbiology","volume":"115 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-12-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132310909","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

SARS-CoV-2 Antibody response to the Sputnik Vaccine in previous infected Patients and non-infected one 既往感染者和未感染者对Sputnik疫苗的SARS-CoV-2抗体反应

Archives of Clinical and Medical Microbiology Pub Date : 2022-12-01 DOI: 10.1101/2022.11.30.22282668

M. Abdulsamad, F. Ebrahim, S. Tabal, S. Bashir, A. Aburgiga, M. Milad, M. Bareem

{"title":"SARS-CoV-2 Antibody response to the Sputnik Vaccine in previous infected Patients and non-infected one","authors":"M. Abdulsamad, F. Ebrahim, S. Tabal, S. Bashir, A. Aburgiga, M. Milad, M. Bareem","doi":"10.1101/2022.11.30.22282668","DOIUrl":"https://doi.org/10.1101/2022.11.30.22282668","url":null,"abstract":"The begging of 2020 saw the development and trials of vaccines against Covid-19 at an unprecedented pace. The first half of 2021 has seen vaccine rollout in many countries, on the other hand, Immunity to covid-19 has exhibited to minimize the risk of having a severe infection and initiate an excellent degree against the disease. This study compares Anti-Spike IgG antibodies among vaccinated people with or without previous exposure to the coronavirus. To determine whether a single dose of sputnik V can produce significant antibody titer amongst previously infected cases and design vaccine dosage regimens accordingly. This study was performed at the Libyan biotechnology research Centre from August 2021 to December 2021. Blood samples were collected from 1811 adult males and females vaccinated with and without a history of exposure to covid-19. Previously infected individuals' record was noted separately. Samples were immediately analyzed by Beckman Unicel Dxl 600, Access immunoassay system. Data were analyzed using GraphPad Prism 9 Software. A P-value >0.5 was not significant. The Majority of candidates 60% of the total samples were males and on analysis, it was found that 72% of patients were seropositive, on the other hand, individuals who were vaccinated and have naive antibodies from the previous infection showed slightly higher immunological response rather than vaccinated patients without previous infected and this finding can help the policymakers to design a single-dose vaccine regimen for the former category. Keywords: Sputnik V, COVID-19, Antibody, Vaccine.","PeriodicalId":221473,"journal":{"name":"Archives of Clinical and Medical Microbiology","volume":"3 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123030400","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Formulation and Evaluation of Anti-Microbial Herbal Hand Wash Gel Containing Aqueous Extract of Sapindus Mukorossi 皂角水提物抗菌洗手凝胶的研制及评价

Archives of Clinical and Medical Microbiology Pub Date : 2022-11-30 DOI: 10.33140/acmmj.01.01.04

Jagtar Singh, Mohit Sharma, Thakur Prava, Ritik Kaundal, Ritika Behl, Suryadev Tripathi

{"title":"Formulation and Evaluation of Anti-Microbial Herbal Hand Wash Gel Containing Aqueous Extract of Sapindus Mukorossi","authors":"Jagtar Singh, Mohit Sharma, Thakur Prava, Ritik Kaundal, Ritika Behl, Suryadev Tripathi","doi":"10.33140/acmmj.01.01.04","DOIUrl":"https://doi.org/10.33140/acmmj.01.01.04","url":null,"abstract":"Background: Herbal medicines and food products have extensively been looked upon for decades due to their biocompatible nature and the least adverse effects. At the same pace, plant-based cosmetics and toiletries are capturing the market due to their eco-friendly nature and compatibility with human skin. The marketed soaps and hand washes are based on toxic fatty acid salts, surfactants, and perfumes that are not only harmful to the skin but to the environment as well. The commonly used surfactant in soaps and hand washes, sodium lauryl sulfate makes the skin dry and sensitive. Moreover, the water getting polluted by SLS when entering the water bodies, makes the aquatic life vulnerable. So, it becomes important to formulate such hand washes that are biocompatible, without compromising their cleansing action and anti-microbial properties. This piece of work explores the formulation of an anti-bacterial hand wash having a good cleansing action to serve the purpose of maintaining personal hygiene in a biocompatible and eco-friendly way. Results: Herbal hand wash gel was prepared and evaluated using plant extracts, having potent anti-microbial action (minimum inhibitory concentration of 1.4cm and 3.7 cm for S. aureus and P.aeruginosa respectively). Conclusion: Formulation of plant based hand wash products by replacing the synthetic surfactants with natural saponins and antimicrobial extracts can be useful for regular use on skin, while reducing the toxic load on environment as well.","PeriodicalId":221473,"journal":{"name":"Archives of Clinical and Medical Microbiology","volume":"37 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-11-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122538772","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Characterization of Lantana Camara Roots (Pentacyclic Triterpenoid) and Mutagenicity Testing of Extracted Oleanolic Acid Using Salmonella Typhimurium 山楂根(五环三萜)的特性及鼠伤寒沙门氏菌提取齐墩果酸的致突变性试验

Archives of Clinical and Medical Microbiology Pub Date : 2022-11-22 DOI: 10.33140/acmmj.01.01.03

Researc H Article, Navika Gupta, S. Chandra, Anu T. Singh, M. Jaggi

{"title":"Characterization of Lantana Camara Roots (Pentacyclic Triterpenoid) and Mutagenicity Testing of Extracted Oleanolic Acid Using Salmonella Typhimurium","authors":"Researc H Article, Navika Gupta, S. Chandra, Anu T. Singh, M. Jaggi","doi":"10.33140/acmmj.01.01.03","DOIUrl":"https://doi.org/10.33140/acmmj.01.01.03","url":null,"abstract":"The objective of the present study was to isolate oleanolic acid from the roots of Lantana camara, and characterize it chemically using DSC, HPLC, and FTIR methods, and additionally carrying out a short term assay for assessment of its mutagenic potential by conducting bacterial reverse mutation test to evaluate the ability of the “Oleanolic acid (Pentacyclic Triterpenoid)” to induce point mutations in tester strains of Salmonella typhimurium in both presence and absence of exogenous metabolic activation system (S9) containing microsomal enzymes. Differential scanning calorimetry (DSC), High Performance Liquid chromatography (HPLC), and Fourier transform infrared (FTIR) spectrometers were used to chemically analyze the isolated molecule. Oleanolic acid was utilized to carry out Preliminary Cytotoxicity and mutagenicity study. According to the results of spectrophotometric research, oleanolic acid extracted from Lantana camara roots exhibits identical spectrum characteristics to standard oleanolic acid also the mutagenic potential of Oleanolic acid (Pentacyclic Triterpenoid). Oleanolic acid was found to be non-mutagenic in all five test strains of Salmonella typhimurium—TA98, TA100, TA102, TA1535, and TA1537 employing plate incorporation assays. It may be determined that oleanolic acid isolated from Lantana camara roots gives identical, identifiable signals and absorbance like previously reported reference standard based on the results of DLC, HPLC, and FTIR spectra and their interpretation and was determined that oleanolic acid purified from Lantana camara roots is non-mutagenic in Salmonella typhimurium.","PeriodicalId":221473,"journal":{"name":"Archives of Clinical and Medical Microbiology","volume":"56 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-11-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121660839","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Assessment of Knowledge on Hepatitis B infection, Hepatitis B Vaccine and Vaccination Status Among Health Care Workers in Tikur Anbessa Specialized Hospital 提库尔安贝萨专科医院医护人员乙型肝炎感染知识、乙型肝炎疫苗接种情况评估

Archives of Clinical and Medical Microbiology Pub Date : 2022-11-01 DOI: 10.33140/acmmj.01.01.02

{"title":"Assessment of Knowledge on Hepatitis B infection, Hepatitis B Vaccine and Vaccination Status Among Health Care Workers in Tikur Anbessa Specialized Hospital","authors":"","doi":"10.33140/acmmj.01.01.02","DOIUrl":"https://doi.org/10.33140/acmmj.01.01.02","url":null,"abstract":"Background: Hepatitis B infection is usually higher among health workers than the general population, particularly in the sub-Saharan region. WHO recommends vaccination for all health care workers (HCWs) against the highly infectious, blood borne virus: HBV. However, previous studies reported that knowledge of HCWs toward the hepatitis B infection, Hepatitis B vaccine and their vaccination coverage was low and vary among HCWs in different settings. Objective: This study was aimed to assess knowledge about HBV infection, HBV vaccine and status of HBV vaccination among healthcare workers in TASH, Addis Ababa, Ethiopia from March 10 to September 10, 2020. Methods and Materials: Hospital based cross-sectional study was conducted on 358 HCWs who were selected randomly. Stratified random sampling method was used to collect the data using self-administered questionnaire. Then, the data was entered into Epi-data 4.2 version and was exported to Statistical Package for Social Science (SPSS) version 26 for analysis. All covariates that showed p value < 0.25 in binary logistic analysis were further analyzed by multiple logistic regressions to detect true predictors. Result: Among the health care workers, who participated in this study, 180 (51.4%) of them had adequate knowledge on the HBV infection. Medical doctors were the most knowledgeable among the HCWs, with interns [AOR=11.3(95% CI=4.5- 28.6)], consultant physicians [AOR=7(95% CI=3.1-15.9)] & resident physicians [AOR=3.5(95% CI=1.9-6.9)] being significant predictors of good knowledge. Vaccination coverage was 60% which was predicted by a shorter work experience [AOR=4.7(95%=1.4-5.8)]. Conclusion: This study reveals that general knowledge level of HCWs about HBV is inadequate and vaccine coverage is suboptimal. Thus, concerned stakeholders should devote more efforts to improve the health care workers awareness about the virus and role of its vaccine and also more work to avail vaccine","PeriodicalId":221473,"journal":{"name":"Archives of Clinical and Medical Microbiology","volume":"22 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116487326","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Pharmacology and Therapeutic Potential of Pcsk9 Inhibitors Pcsk9抑制剂的药理学和治疗潜力

Archives of Clinical and Medical Microbiology Pub Date : 2022-10-31 DOI: 10.33140/acmmj.01.01.01

引用次数: 0

The application of Artificial Intelligence to Ophthalmology: A bibliometric study (2000-2021) 人工智能在眼科中的应用:文献计量学研究(2000-2021)

Archives of Clinical and Medical Microbiology Pub Date : 2021-11-03 DOI: 10.20944/preprints202111.0080.v1

Han Wang, Xiaoshu Zhou, W. Du, Lina Huang

{"title":"The application of Artificial Intelligence to Ophthalmology: A bibliometric study (2000-2021)","authors":"Han Wang, Xiaoshu Zhou, W. Du, Lina Huang","doi":"10.20944/preprints202111.0080.v1","DOIUrl":"https://doi.org/10.20944/preprints202111.0080.v1","url":null,"abstract":"Background. Artificial Intelligence (AI) is an advanced technology for the latest 20 years. Machine learning (ML) and deep learning (DL) are the major innovations for AI, which has been applied for multiple fields. Ophthalmology has become to be one of the most significant disciplines for human healthcare. Methodology. This study utilizes methods of text mining and bibliometric analysis to explore applications of AI to ophthalmology. 179 related articles from Web of Science (WOS) and 96 papers from China National Knowledge Infrastructure (CNKI) are explored during the period of 2000 to 2021. A descriptive analysis of major trends, journal releasing, topic mapping and quotation relationships is implemented in this paper. Leading authors, journals, institutions, nations and references in the related research are identified. Results. Findings show that the application of AI technologies in ophthalmologic diagnosis with optical coherence tomography (OCT) fundus images is the core topic for this area’s studies, especially for diabetic retinopathy (DR), aged macular degeneration (AMD) and glaucoma. It is also be predicted as the core direction over the recent years. Besides, The USA, England and China is the most competitive countries in this scientific filed. Journals of Ophthalmology, Investigative Ophthalmology and Visual Science, Eye, Acta Ophthalmologica and Scientific Reports are the top five journal related to the research area. There is a significant difference between WOS and CNKI databases pertaining to the application of Artificial Intelligence (AI) to ophthalmology, especially for the historic development, topic mapping and discipline category. Finally, the potential academic value of interdisciplinary subject of “AI in Ophthalmology” and tradition Chinese medicine (TRM) is discussed. Limitations and suggestions for the future research is indicated at the end of this paper.","PeriodicalId":221473,"journal":{"name":"Archives of Clinical and Medical Microbiology","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-11-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132137775","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1