{"title":"Death of plant cells and their contribution to rumen function.","authors":"A. Kingston-Smith, M. Theodorou","doi":"10.1201/9781003076889-22","DOIUrl":"https://doi.org/10.1201/9781003076889-22","url":null,"abstract":"","PeriodicalId":22134,"journal":{"name":"Symposia of the Society for Experimental Biology","volume":"31 1","pages":"289-99"},"PeriodicalIF":0.0,"publicationDate":"2021-12-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86421298","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Tissue transglutaminase in cell death.","authors":"M. Griffin, E. Verderio","doi":"10.1201/9781003076889-17","DOIUrl":"https://doi.org/10.1201/9781003076889-17","url":null,"abstract":"","PeriodicalId":22134,"journal":{"name":"Symposia of the Society for Experimental Biology","volume":"33 1","pages":"223-40"},"PeriodicalIF":0.0,"publicationDate":"2021-12-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85657667","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Regulation of cell cycle arrest and cell death--alternative responses to DNA damage.","authors":"C. Norbury","doi":"10.1201/9781003076889-16","DOIUrl":"https://doi.org/10.1201/9781003076889-16","url":null,"abstract":"","PeriodicalId":22134,"journal":{"name":"Symposia of the Society for Experimental Biology","volume":"52 1","pages":"213-22"},"PeriodicalIF":0.0,"publicationDate":"2021-12-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87451232","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Tumour cell death.","authors":"I. Bowen, F. Amin","doi":"10.1201/9781003076889-19","DOIUrl":"https://doi.org/10.1201/9781003076889-19","url":null,"abstract":"","PeriodicalId":22134,"journal":{"name":"Symposia of the Society for Experimental Biology","volume":"17 1","pages":"253-64"},"PeriodicalIF":0.0,"publicationDate":"2021-12-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83559368","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Avian coccidiosis: a disturbed host-parasite relationship to be restored.","authors":"A. Vermeulen","doi":"10.4324/9780203487709-10","DOIUrl":"https://doi.org/10.4324/9780203487709-10","url":null,"abstract":"The co-evolution of Eimeria and its host the domestic chicken has resulted in a delicate balance of mutual understanding and respect. This balance has been broken by the complete change of the environment in which the parasite was able to reproduce to such an extent that the host, stressed and weakened by heat, crowding and concurrent infections could not combat the shear numbers of organisms. The use of drugs to control the situation has been shown to only temporarily create relief. Resistance widely developed by the flexible genome of the parasite returned new drugs at a greater speed than they had been developed. Improved hygienic measures, better facility management and good understanding of epidemiology of the parasites spreading and proliferation seem the first and most promising set of tools to control the balance. Reduction of stock density may only provide any relief if this is done at a factor of 10 or higher and this is not a realistic measure in relation to the profit. Free-range chickens are an alternative if only animal welfare is at stake. However, in terms of prevalence of parasitic infections, such as coccidia, helminthes or ectoparasites, chickens do not seem to be better off (Permin et al., 2002). Immunological surveillance and the development of safe, effective and economical vaccines are further refinements that can be used to restore the relationship between parasite and host. Several live vaccines are effective and applied, but certainly have drawbacks in safety and production. New technology such as recombinant vectors together with a better understanding of the cell biology of the parasite from biological and genomic information should provide improved vaccines for the future. The strong genetically determined characteristics involved in the induction and maintenance of a sustainable protective immune response might turn out to be of decisive importance for the success of these strategies. The consequences for the physiology of the parasite remain to be understood.","PeriodicalId":22134,"journal":{"name":"Symposia of the Society for Experimental Biology","volume":"31 1","pages":"211-41; discussion 243-5"},"PeriodicalIF":0.0,"publicationDate":"2004-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82099826","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Nuclear dynamics in higher plants.","authors":"David W Galbraith","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":22134,"journal":{"name":"Symposia of the Society for Experimental Biology","volume":" 56","pages":"217-28"},"PeriodicalIF":0.0,"publicationDate":"2004-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"24831498","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Comparative aspects of the tick-host relationship: immunobiology, genomics and proteomics.","authors":"F. Alarcón-Chaidez, S. Wikel","doi":"10.4324/9780203487709-9","DOIUrl":"https://doi.org/10.4324/9780203487709-9","url":null,"abstract":"","PeriodicalId":22134,"journal":{"name":"Symposia of the Society for Experimental Biology","volume":"31 1","pages":"185-209; discussion 243-5"},"PeriodicalIF":0.0,"publicationDate":"2004-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78980867","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The nuclear envelope: a comparative overview.","authors":"David E Evans, John A Bryant, Chris Hutchison","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":22134,"journal":{"name":"Symposia of the Society for Experimental Biology","volume":" 56","pages":"1-8"},"PeriodicalIF":0.0,"publicationDate":"2004-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"24830960","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Calcium/calmodulin-binding transcription activators in plants and animals.","authors":"Fawzi Taleb, Hillel Fromm","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":22134,"journal":{"name":"Symposia of the Society for Experimental Biology","volume":" 56","pages":"297-315"},"PeriodicalIF":0.0,"publicationDate":"2004-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"24831503","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"All in the family: evidence for four new LEM-domain proteins Lem2 (NET-25), Lem3, Lem4 and Lem5 in the human genome.","authors":"Kenneth K Lee, Katherine L Wilson","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>LEM-domain proteins share a folded structure, the 'LEM-domain', which binds a conserved chromatin protein named BAF. Most LEM-domain proteins are found at the nuclear membrane, but some are nucleoplasmic. All characterized members of this family bind nuclear lamin filaments. We summarize the 'founding' LEM-domain proteins LAP2, emerin and MAN1 ('SANE' or 'XMAN' in Xenopus) and their emerging roles in gene regulation and nuclear assembly. These roles are placed in the context of human diseases ('laminopathies') caused by mutations in either emerin or A-type lamins. Other LEM-domain proteins might modify the phenotype or severity of human laminopathy, or cause new laminopathies. We summarize evidence that the human genome encodes at least four additional LEM-domain proteins, designated Lem2 (NET-25), Lem3, Lem4 and Lem5. Early adaptation of a consistent nomenclature, such as the \"Lem\" names proposed here, will facilitate rapid progress in this field. Further investigation of 'founder' and novel members of this family will be important to understand nuclear structure, and presents new opportunities to understand human disease.</p>","PeriodicalId":22134,"journal":{"name":"Symposia of the Society for Experimental Biology","volume":" 56","pages":"329-39"},"PeriodicalIF":0.0,"publicationDate":"2004-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"24831505","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}