Stroke最新文献

{"title":"Dilemmas in Secondary Stroke Prevention.","authors":"Stephanie Vu, Noor Mahmoud, Shravan Sivakumar, Forough Yazdanian, Marc Fisher","doi":"10.1161/STROKEAHA.124.050403","DOIUrl":"10.1161/STROKEAHA.124.050403","url":null,"abstract":"<p><p>Secondary stroke prevention encompasses many approaches, including antithrombotic therapy, risk factor management, and a healthy lifestyle. Recommendations are typically based on the results of randomized clinical trials that provide evidence of benefit. However, in some situations, clinicians extrapolate the results of clinical trials into everyday practice, or trials have not provided sufficient information to make treatment decisions. This review will discuss 4 scenarios: dual-antiplatelet therapy, the perils of combining antiplatelet and anticoagulation, indications for statin therapy, and therapeutic considerations for patients with paroxysmal atrial fibrillation.</p>","PeriodicalId":21989,"journal":{"name":"Stroke","volume":" ","pages":"1938-1946"},"PeriodicalIF":7.8,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144000165","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Amyloid Presence in Acute Ischemic Stroke Thrombi: Observational Evidence for Fibrinolytic Resistance.","authors":"Justine M Grixti, Arun Chandran, Jan-Hendrik Pretorius, Melanie Walker, Alakendu Sekhar, Etheresia Pretorius, Douglas B Kell","doi":"10.1161/STROKEAHA.124.050033","DOIUrl":"10.1161/STROKEAHA.124.050033","url":null,"abstract":"","PeriodicalId":21989,"journal":{"name":"Stroke","volume":" ","pages":"e165-e167"},"PeriodicalIF":7.8,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12180706/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144151873","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Gestational Diabetes and Risk of Stroke Among US Black Women.","authors":"Shanshan Sheehy, Hugo J Aparicio, Nuo N Xu, Vasileios-Arsenios Lioutas, Julie G Shulman, Lynn Rosenberg","doi":"10.1161/STROKEAHA.124.050517","DOIUrl":"10.1161/STROKEAHA.124.050517","url":null,"abstract":"<p><strong>Background: </strong>There is a paucity of evidence on whether gestational diabetes (GDM) is a risk factor for cerebral vascular disease for Black women and lack of data on incident stroke as end point.</p><p><strong>Methods: </strong>We conducted a large prospective cohort study of Black women across the United States and assessed the association between self-reported history of GDM and incident stroke. The study began when participants became parous or enrolled in 1995. We followed up 41 143 parous Black women who were free of cerebral vascular disease or cancer and followed up until incident stroke, death, or the end of 2021. Our exposure was self-reported history of GDM, and outcome was incident stroke. Multivariable Cox proportional hazards model was used to estimate hazard ratios (HRs) and 95% CIs, adjusting for major known risk factors for stroke.</p><p><strong>Results: </strong>A total of 1495 incident stroke cases were identified among 41 143 Black women from 1995 until 2021 (881 505 person-years of follow-up). Black women with a history of GDM had a consistent 1.4-fold increased risk of stroke compared with those with a healthy pregnancy (age-adjusted HR, 1.44 [95% CI, 1.14-1.82]; multivariable HR, 1.41 [95% CI, 1.11-1.79]). Compared with healthy parous women with neither GDM nor type 2 diabetes, women with a history of both had a 2.6-fold increased stroke risk (multivariable HR, 2.59 [95% CI, 1.88-3.57]); women with only type 2 diabetes have 2-fold increased stroke risk (multivariable HR, 2.04 [95% CI, 1.79-2.32]); women with a history of GDM but no progression to type 2 diabetes do not have an increased risk of stroke (multivariable HR, 1.22 [95% CI, 0.86-1.73]).</p><p><strong>Conclusions: </strong>In this large prospective study of Black women, a vulnerable population at high risk for stroke, a history of GDM increased stroke incidence by 41%. There was no elevated risk of stroke for Black women with a history of GDM and no progression to type 2 diabetes, while the stroke risk increased by 2.6-fold for Black women with GDM and progression to type 2 diabetes. Our results highlight the importance of consideration of history of GDM for stroke early prevention, especially Black women with progression to T2DM after GDM.</p>","PeriodicalId":21989,"journal":{"name":"Stroke","volume":" ","pages":"1779-1785"},"PeriodicalIF":7.8,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12187534/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144027211","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Endovascular Therapy for Late-Window M2-Segment Middle Cerebral Artery Occlusion: Analysis of the CLEAR Study.","authors":"Simon Winzer, Daniel P O Kaiser, Muhammad M Qureshi, Alicia C Castonguay, Daniel Strbian, Raul G Nogueira, Simon Nagel, Jean Raymond, Mohamad Abdalkader, Jelle Demeestere, João Pedro Marto, Hiroshi Yamagami, Kanta Tanaka, Sunil A Sheth, Anne Dusart, Patrik Michel, Marta Olive Gadea, Marc Ribo, Osama O Zaidat, Diogo C Haussen, Hilde Henon, Mahmoud H Mohammaden, Markus A Möhlenbruch, James E Siegler, Ajit S Puri, Johannes Kaesmacher, Piers Klein, Liisa Tomppo, Francois Caparros, João Nuno Ramos, Mouhammad Jumaa, Syed Zaidi, Nicolas Martinez-Majander, Stefania Nannoni, Lieselotte Vandewalle, Flavio Bellante, Milagros Galecio-Castillo, Sergio Salazar-Marioni, Pekka Virtanen, Anke Wouters, Rita Ventura, Jessica Jesser, Adnan Mujanovic, Liqi Shu, Abiya Qureshi, Zhongming Qiu, Hesham E Masoud, Manuel Requena, Mikko Sillanpää, Wei Hu, Eugene Lin, Charlotte Cordonnier, Daniel Roy, Shadi Yaghi, Davide Strambo, Urs Fischer, Santiago Ortega-Gutierrez, Robin Lemmens, Peter A Ringleb, Thanh N Nguyen, Volker Puetz","doi":"10.1161/STROKEAHA.124.048840","DOIUrl":"10.1161/STROKEAHA.124.048840","url":null,"abstract":"<p><strong>Background: </strong>There is uncertainty about whether patients with M2 occlusion benefit from endovascular therapy (EVT) in the late (6-24-hour) time window. We evaluated the clinical outcomes of patients with M2 occlusion selected for EVT compared with those who received medical management (MM) in the late window.</p><p><strong>Methods: </strong>This multinational cohort study was conducted at 66 sites across 10 countries (January 2014 to May 2022). We included consecutive patients with late-window stroke due to M2 occlusion, baseline National Institutes of Health Stroke Scale score of ≥5, and premorbid modified Rankin Scale score of ≤2 who received EVT or MM alone. The primary end point was 90-day ordinal shift in the modified Rankin Scale score. Safety end points were symptomatic intracranial hemorrhage and 90-day mortality. Differences in outcomes were determined using inverse probability of treatment weighting-adjusted logistic regression models.</p><p><strong>Results: </strong>Among 5098 patients, 496 met inclusion criteria (median [interquartile range] age, 74 years [62-81 years]; baseline National Institutes of Health Stroke Scale score, 12 [8-17]), of whom 394 (79.4%) received EVT and 102 (20.6%) MM. In inverse probability of treatment weighting adjusted analyses, there was no favorable 90-day ordinal modified Rankin Scale shift (odds ratio, 1.39 [95% CI, 0.92-2.12]) and no difference of functional independence rates (modified Rankin Scale score of 0-2; odds ratio, 1.72 [95% CI, 0.93-3.15]) with EVT compared with MM. Moreover, symptomatic intracranial hemorrhage risk (odds ratio, 3.46 [95% CI, 0.50-23.92]) and 90-day mortality (odds ratio, 1.11 [95% CI, 0.66-1.87]) were not statistically different between treatment groups.</p><p><strong>Conclusions: </strong>In patients with M2 occlusion in the 6- to 24-hour time window, there was no difference in disability outcomes or symptomatic intracranial hemorrhage risk between patients treated with EVT compared with MM. Results of ongoing randomized trials will provide further insight.</p><p><strong>Registration: </strong>URL: https://www.clinicaltrials.gov; Unique identifier: NCT04096248.</p>","PeriodicalId":21989,"journal":{"name":"Stroke","volume":" ","pages":"1671-1680"},"PeriodicalIF":7.8,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144128715","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Blood-Brain Barrier Leakage in the Penumbra Is Associated With Infarction on Follow-Up Imaging in Acute Ischemic Stroke.","authors":"Felix L Nägele, Lauranne Scheldeman, Anke Wouters, Marlene Heinze, Marvin Petersen, Eckhard Schlemm, Maximilian Schell, Martin Ebinger, Matthias Endres, Jochen B Fiebach, Jens Fiehler, Ivana Galinovic, Robin Lemmens, Keith W Muir, Norbert Nighoghossian, Salvador Pedraza, Josep Puig, Claus Z Simonsen, Vincent Thijs, Götz Thomalla, Bastian Cheng","doi":"10.1161/STROKEAHA.124.050171","DOIUrl":"10.1161/STROKEAHA.124.050171","url":null,"abstract":"<p><strong>Background: </strong>Blood-brain barrier (BBB) leakage measured with dynamic susceptibility contrast-enhanced magnetic resonance imaging (MRI) has been associated with hemorrhagic transformation in acute ischemic stroke. However, the influence of prethrombolysis BBB leakage on infarct growth has not been studied. Therefore, we aimed to characterize BBB integrity according to tissue state at admission and tissue fate on follow-up MRI.</p><p><strong>Methods: </strong>This is a post hoc analysis of the WAKE-UP trial (Efficacy and Safety of MRI-Based Thrombolysis in Wake-Up Stroke). Ischemic cores were segmented on diffusion-weighted imaging at baseline and on fluid-attenuated inversion recovery images at follow-up (22-36 hours). Dynamic susceptibility contrast-enhanced-MRI provided penumbra masks (time to maximum of the tissue residue function >6 s minus ischemic core) and BBB leakage (extraction fraction [EF], <i>Z</i> scored) maps via automated analysis. EF was averaged within the ischemic core, total penumbra, 2 penumbra subtypes (salvaged/infarcted penumbra), and normal tissue. Adjusted linear mixed-effects models tested for differences between tissue types and associations of EF with clinical/imaging outcomes. Complementary voxel-wise analyses were performed.</p><p><strong>Results: </strong>Of 503 patients enrolled in the trial, 165 with suitable dynamic susceptibility contrast-enhanced-MRI data were included in this analysis (mean age 66 years, 38% women, median National Institutes of Health Stroke Scale score of 6; 53% receiving alteplase). EF was significantly increased in the ischemic core and penumbra relative to normally perfused tissue, while differences between total penumbra and ischemic core were statistically nonsignificant. Infarcted penumbra exhibited higher EF than salvaged penumbra, even after adjusting for hypoperfusion severity (<i>P</i><0.001, n=79 with baseline penumbral tissue and follow-up MRI). Voxel-wise analyses showed a significant association between EF and voxel-level infarction in the placebo group only. EF did not predict hemorrhagic transformation or functional outcomes.</p><p><strong>Conclusions: </strong>Penumbral BBB leakage may identify tissue at increased risk of infarction. Larger, prospective studies are needed to determine the clinical relevance of BBB leakage as an imaging marker of tissue fate.</p><p><strong>Registration: </strong>URL: https://www.clinicaltrials.gov; Unique identifier: NCT01525290. URL: https://eudract.ema.europa.eu/; Unique identifier: 2011-005906-32.</p>","PeriodicalId":21989,"journal":{"name":"Stroke","volume":" ","pages":"1832-1842"},"PeriodicalIF":7.8,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12180707/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144023784","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Quantitative Ischemic Lesions of Portable Low-Field Strength MRI Using Deep Learning-Based Super-Resolution.","authors":"Yueyan Bian, Long Wang, Jin Li, Xiaoxu Yang, Erling Wang, Yingying Li, Yuehong Liu, Lei Xiang, Qi Yang","doi":"10.1161/STROKEAHA.124.050540","DOIUrl":"10.1161/STROKEAHA.124.050540","url":null,"abstract":"<p><strong>Background: </strong>Deep learning-based synthetic super-resolution magnetic resonance imaging (SynthMRI) may improve the quantitative lesion performance of portable low-field strength magnetic resonance imaging (LF-MRI). The aim of this study is to evaluate whether SynthMRI improves the diagnostic performance of LF-MRI in assessing ischemic lesions.</p><p><strong>Methods: </strong>We retrospectively included 178 stroke patients and 104 healthy controls with both LF-MRI and high-field strength magnetic resonance imaging (HF-MRI) examinations. Using HF-MRI as the ground truth, the deep learning-based super-resolution framework (SCUNet [Swin-Conv-UNet]) was pretrained using large-scale open-source data sets to generate SynthMRI images from LF-MRI images. Participants were split into a training set (64.2%) to fine-tune the pretrained SCUNet, and a testing set (35.8%) to evaluate the performance of SynthMRI. Sensitivity and specificity of LF-MRI and SynthMRI were assessed. Agreement with HF-MRI for Alberta Stroke Program Early CT Score in the anterior and posterior circulation (diffusion-weighted imaging-Alberta Stroke Program Early CT Score and diffusion-weighted imaging-posterior circulation Alberta Stroke Program Early CT Score) was evaluated using intraclass correlation coefficients (ICCs). Agreement with HF-MRI for lesion volume and mean apparent diffusion coefficient (ADC) within lesions was assessed using both ICCs and Pearson correlation coefficients.</p><p><strong>Results: </strong>SynthMRI demonstrated significantly higher sensitivity and specificity than LF-MRI (89.0% [83.3%-94.6%] versus 77.1% [69.5%-84.7%]; <i>P</i><0.001 and 91.3% [84.7%-98.0%] versus 71.0% [60.3%-81.7%]; <i>P</i><0.001, respectively). The ICCs of diffusion-weighted imaging-Alberta Stroke Program Early CT Score between SynthMRI and HF-MRI were also better than that between LF-MRI and HF-MRI (0.952 [0.920-0.972] versus 0.797 [0.678-0.876], <i>P</i><0.001). For lesion volume and mean apparent diffusion coefficient within lesions, SynthMRI showed significantly higher agreement (<i>P</i><0.001) with HF-MRI (ICC>0.85, <i>r</i>>0.78) than LF-MRI (ICC>0.45, <i>r</i>>0.35). Furthermore, for lesions during various poststroke phases, SynthMRI exhibited significantly higher agreement with HF-MRI than LF-MRI during the early hyperacute and subacute phases.</p><p><strong>Conclusions: </strong>SynthMRI demonstrates high agreement with HF-MRI in detecting and quantifying ischemic lesions and is better than LF-MRI, particularly for lesions during the early hyperacute and subacute phases.</p>","PeriodicalId":21989,"journal":{"name":"Stroke","volume":" ","pages":"1843-1852"},"PeriodicalIF":7.8,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144039245","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Poverty and Stroke: The Need for Socioeconomic Data in Hyperacute Care.","authors":"Mayank Goyal, Michael D Hill, Jeffery L Saver, Nishita Singh","doi":"10.1161/STROKEAHA.125.050669","DOIUrl":"https://doi.org/10.1161/STROKEAHA.125.050669","url":null,"abstract":"<p><p>Poverty profoundly influences stroke risk, access to care, and recovery, yet remains largely invisible in hyperacute stroke trials. Despite growing awareness of health inequities, current research and clinical frameworks rarely capture socioeconomic data at the point of care-particularly during the hyperacute phase, when decisions are time sensitive. This commentary highlights the urgent need to incorporate measures of poverty and social vulnerability into hyperacute stroke care and research. We briefly review existing evidence on the relationship between socioeconomic status and acute stroke outcomes, identify gaps in current data collection practices, and explore why capturing such information has remained a challenge. To address this gap, we propose a practical, rapid-assessment approach using brief, validated tools to measure economic strain in emergency or prehospital settings. These tools can be embedded into clinical workflows with minimal disruption while providing critical context for interpreting outcomes and guiding resource allocation. We envision incorporating such tools into future randomized controlled trials to ensure that socioeconomic factors are systematically captured and analyzed-ultimately enabling more inclusive trial designs, equitable care delivery, and data-driven policy change.</p>","PeriodicalId":21989,"journal":{"name":"Stroke","volume":"56 7","pages":"1965-1968"},"PeriodicalIF":7.8,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144476689","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Recent Advances in Stroke Surgery.","authors":"Johanna M Ospel, Giuseppe Lanzino","doi":"10.1161/STROKEAHA.124.049885","DOIUrl":"https://doi.org/10.1161/STROKEAHA.124.049885","url":null,"abstract":"","PeriodicalId":21989,"journal":{"name":"Stroke","volume":"56 7","pages":"1914-1916"},"PeriodicalIF":7.8,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144476690","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Does Vessel Occlusion Drive the Harmful Effect of Very Early Mobilization in Patients With Ischemic Stroke?: A Post Hoc Analysis of AVERT.","authors":"Tina Kaffenberger, Julie Bernhardt, Vincent N Thijs, Leonid Churilov, Hannah Johns, Gagan Sharma, Bruce C V Campbell, Nawaf Yassi","doi":"10.1161/STROKEAHA.124.047349","DOIUrl":"10.1161/STROKEAHA.124.047349","url":null,"abstract":"<p><strong>Background: </strong>The international trial AVERT (A Very Early Rehabilitation Trial) found that very early mobilization (VEM; commenced <24 hours after stroke) negatively affected functional outcome (modified Rankin Scale [mRS]). The drivers of this effect remain unclear. One plausible mechanism is that high-dose upright activity worsens cerebral perfusion in patients with cerebral large vessel occlusion (LVO). For this retrospective AVERT substudy, we collected brain imaging from participants from 8 AVERT sites (n=910) to explore the potential relationship between LVO, VEM, and mRS in ischemic stroke. We hypothesized that patients with evidence of LVO would be adversely affected by VEM compared with non-LVO patients.</p><p><strong>Methods: </strong>In this post hoc analysis of a randomized controlled trial, 2 neurologists independently classified patients with ischemic stroke as having LVO via direct (vessel truncation on computed tomography/magnetic resonance imaging angiography) or indirect evidence (hyperdense artery sign or established infarction of >2/3 of an arterial territory) from brain imaging obtained ≤7 days poststroke. The associations between LVO, VEM, and 3- and 12-month mRS was tested using logistic regression, adjusted for age, treatment with thrombolysis, and baseline National Institutes of Health Stroke Scale.</p><p><strong>Results: </strong>Interrater reliability for LVO signs was high (weighted κ, 0.842 [95% CI, 0.631-0.969]). Of 689 participants (37.2% female; median age, 74.5 [interquartile range, 65.0-81.2] years) included in the primary analysis, 192 (28%) showed direct or indirect evidence of LVO. Computed tomography/magnetic resonance imaging angiography were available in 179 (26%) of those 689 participants. While LVO was associated with poor mRS (>2) at 3 months (adjusted odds ratio, 2.15 [95% CI, 1.29-3.64]) and 12 months (adjusted odds ratio, 1.76 [95% CI, 1.1-2.84]; <i>P</i>=0.02), there was no significant interaction between VEM, LVO, and mRS (<i>P</i>=0.16).</p><p><strong>Conclusions: </strong>We found no evidence that VEM was specifically harmful in patients with LVO. However, as arterial imaging was not consistently obtained before first mobilization, larger prospective studies with standardized measures of LVO are needed to fully address this question.</p><p><strong>Registration: </strong>URL: https://anzctr.org.au/Trial/Registration/TrialReview.aspx?id=1266&isReview=true; Unique identifier: ACTRN12606000185561.</p>","PeriodicalId":21989,"journal":{"name":"Stroke","volume":" ","pages":"1689-1692"},"PeriodicalIF":7.8,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143982737","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Advice and Tips for Achieving Work-Life Balance for Early Career Researchers.","authors":"Muyassar Mamtilahun, Mian Wang, Wanlu Li","doi":"10.1161/STROKEAHA.124.047081","DOIUrl":"https://doi.org/10.1161/STROKEAHA.124.047081","url":null,"abstract":"","PeriodicalId":21989,"journal":{"name":"Stroke","volume":"56 7","pages":"e174-e177"},"PeriodicalIF":7.8,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144476685","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}