Research & Review: Drugs and Drugs Development最新文献

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Review on Hematinic Formulations Used in Anaemia Deficiency Disorders 血液学制剂在贫血缺乏性疾病中的应用综述
Research & Review: Drugs and Drugs Development Pub Date : 2023-06-05 DOI: 10.46610/rrddd.2023.v05i02.001
Vishal Bodke, Ruchita Badekar, P. Dhoble, Swati Yadav, Prajval Birajdar, Mangesh Dagle
{"title":"Review on Hematinic Formulations Used in Anaemia Deficiency Disorders","authors":"Vishal Bodke, Ruchita Badekar, P. Dhoble, Swati Yadav, Prajval Birajdar, Mangesh Dagle","doi":"10.46610/rrddd.2023.v05i02.001","DOIUrl":"https://doi.org/10.46610/rrddd.2023.v05i02.001","url":null,"abstract":"Whenever the body has inadequate amounts of healthy red blood cells that supply oxygen to the body's organs, anaemia develops. Anaemia patients experience coldness, fatigue, and weakness. Iron deficiency anaemia is the most prevalent kind of anaemia. Red blood cells use a protein called haemoglobin, which iron creates, to deliver oxygen. Iron can be added to food to ease it. Anaemia brought on by inflammations brought on by infections, autoimmune disorders, cancer, and chronic kidney diseases is the second most common type of anaemia. In this type of anaemia, the blood iron level is low despite the body having a normal or even increasing quantity of iron stored in body tissues. One of the most common dangerous diseases, especially in women, pregnant women, children, and adults, is anaemia deficiency. According to the World Health Organisation (2007), anaemia affects 30% to 50% of children and other groups as a result of iron deficiency. Out of the worldwide 1.6 billion anaemic populations, several hundred million suffer from iron deficiency anaemia. Therefore, iron deficiency is the main contributing factor to anaemia worldwide. Iron deficiency anaemia affects a part of the two billion persons who are iron nutritionally deficient globally. This hematinic medication, such as (Dexorange, Orofer XT and Feronia XT) is a form of iron supplement used for the treatment or prevention of low iron levels in the blood, which can occur due to anaemia or pregnancy. For the body to create red blood cells and sustain its health, iron is a crucial mineral.","PeriodicalId":217291,"journal":{"name":"Research & Review: Drugs and Drugs Development","volume":"125 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-06-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116280429","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Studies on the Crystal Forms of Tropicamide: Preparation, Characterization and Dissolution Profile Tropicamide晶型的研究:制备、表征及溶出谱
Research & Review: Drugs and Drugs Development Pub Date : 2022-07-19 DOI: 10.46610/rrddd.2022.v04i02.001
{"title":"Studies on the Crystal Forms of Tropicamide: Preparation, Characterization and Dissolution Profile","authors":"","doi":"10.46610/rrddd.2022.v04i02.001","DOIUrl":"https://doi.org/10.46610/rrddd.2022.v04i02.001","url":null,"abstract":"Tropicamide is an anticholinergic drug which is used in the treatment of glaucoma. Polymorphic study of tropicamide is done by using solvents viz Chloroform, Dichloromethane, Isopropanol, Benzene, Acetone, Ethanol, Methanol, Tween 80, Povidone K30, PEG 4000 and Phosphate Buffer. Crystals of all the solvents were made with tropicamide out of which best stability of the compound was found with benzene, acetone, ethanol and methanol. Crystals were compared using various methods like Dissolution, DSC, XRD, and IR spectroscopic.","PeriodicalId":217291,"journal":{"name":"Research & Review: Drugs and Drugs Development","volume":"163 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-07-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125907426","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Botanical, Ethnopharmacological, Phytochemical & Pharmacological Standards of Plant Ichnocarpus frutescens 石竹植物植物学、民族药理学、植物化学和药理学标准
Research & Review: Drugs and Drugs Development Pub Date : 2022-02-19 DOI: 10.46610/rrddd.2022.v04i01.001
Mohsina F.P, A. Quazi, Faheem I. P., A. M., M. Mukim, Abhinandan H. Patil
{"title":"Botanical, Ethnopharmacological, Phytochemical & Pharmacological Standards of Plant Ichnocarpus frutescens","authors":"Mohsina F.P, A. Quazi, Faheem I. P., A. M., M. Mukim, Abhinandan H. Patil","doi":"10.46610/rrddd.2022.v04i01.001","DOIUrl":"https://doi.org/10.46610/rrddd.2022.v04i01.001","url":null,"abstract":"The plant Ichnocarpus frutescens belongs to family Apocynaceae, commonly known as ‘Black creeper’ (In Odia: Syamolota; Hindi: Kali-dudhi, Krishna sariva; Sanskrit: Syamalata, Sariva). It is native to India, China, Java, Ceylon, Southeast Asia, and northern Australia. It is a large, evergreen, woody climbing plant. In India, tribes used this plant as a substitute of Indian Sersaparilla (Hemidesmus indicus). Phytochemical investigation indicates that plant belong to various category viz. phytosterol, triterpenes, flavonoids and various other phenolic compounds. Pharmacological activities of different parts of the plant reported include anti-urolithiasis, hepatoprotective, antioxidant, analgesic, antipyretic, anti-inflammatory, antidiabetic, antihyperlipidemic and antitumor activity etc. The presented review article aims to highlight a brief and comparative data on botanical, ethnopharmacological, phytochemical & pharmacological standards of plant Ichnocarpus frutescens.","PeriodicalId":217291,"journal":{"name":"Research & Review: Drugs and Drugs Development","volume":"39 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-02-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131722003","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 3
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