{"title":"Tropicamide晶型的研究:制备、表征及溶出谱","authors":"","doi":"10.46610/rrddd.2022.v04i02.001","DOIUrl":null,"url":null,"abstract":"Tropicamide is an anticholinergic drug which is used in the treatment of glaucoma. Polymorphic study of tropicamide is done by using solvents viz Chloroform, Dichloromethane, Isopropanol, Benzene, Acetone, Ethanol, Methanol, Tween 80, Povidone K30, PEG 4000 and Phosphate Buffer. Crystals of all the solvents were made with tropicamide out of which best stability of the compound was found with benzene, acetone, ethanol and methanol. Crystals were compared using various methods like Dissolution, DSC, XRD, and IR spectroscopic.","PeriodicalId":217291,"journal":{"name":"Research & Review: Drugs and Drugs Development","volume":"163 1","pages":"0"},"PeriodicalIF":0.0000,"publicationDate":"2022-07-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Studies on the Crystal Forms of Tropicamide: Preparation, Characterization and Dissolution Profile\",\"authors\":\"\",\"doi\":\"10.46610/rrddd.2022.v04i02.001\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Tropicamide is an anticholinergic drug which is used in the treatment of glaucoma. Polymorphic study of tropicamide is done by using solvents viz Chloroform, Dichloromethane, Isopropanol, Benzene, Acetone, Ethanol, Methanol, Tween 80, Povidone K30, PEG 4000 and Phosphate Buffer. Crystals of all the solvents were made with tropicamide out of which best stability of the compound was found with benzene, acetone, ethanol and methanol. Crystals were compared using various methods like Dissolution, DSC, XRD, and IR spectroscopic.\",\"PeriodicalId\":217291,\"journal\":{\"name\":\"Research & Review: Drugs and Drugs Development\",\"volume\":\"163 1\",\"pages\":\"0\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2022-07-19\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Research & Review: Drugs and Drugs Development\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.46610/rrddd.2022.v04i02.001\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Research & Review: Drugs and Drugs Development","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.46610/rrddd.2022.v04i02.001","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Studies on the Crystal Forms of Tropicamide: Preparation, Characterization and Dissolution Profile
Tropicamide is an anticholinergic drug which is used in the treatment of glaucoma. Polymorphic study of tropicamide is done by using solvents viz Chloroform, Dichloromethane, Isopropanol, Benzene, Acetone, Ethanol, Methanol, Tween 80, Povidone K30, PEG 4000 and Phosphate Buffer. Crystals of all the solvents were made with tropicamide out of which best stability of the compound was found with benzene, acetone, ethanol and methanol. Crystals were compared using various methods like Dissolution, DSC, XRD, and IR spectroscopic.
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