Sleep Science and Practice最新文献

{"title":"Comparison of the clinical and electrophysiological characteristics between type 1 and type 2 narcolepsy: a cross-sectional study","authors":"Kuniyuki Niijima, Masakazu Wakai","doi":"10.1186/s41606-023-00091-3","DOIUrl":"https://doi.org/10.1186/s41606-023-00091-3","url":null,"abstract":"Abstract Introduction Narcolepsy is a chronic brain disease characterized by excessive sleepiness and classified into two types based on the presence of cataplexy or reduced level of cerebrospinal fluid orexin-A (hypocretine-1): narcolepsy type 1 (NT1) and narcolepsy type 2 (NT2). These two types differ in symptoms other than cataplexy, as well as in certain examination findings. The present study aimed to investigate the clinical and electrophysiological characteristics of NT1 by comparing its features with those of NT2. Methods Subjects were 118 first diagnosed and untreated patients with narcolepsy. They underwent both polysomnography (PSG) and multiple sleep latency test (MSLT) as a sleep test. Diagnosis was established in accordance with International Classification of Sleep Disorders, Third Edition, and the type of narcolepsy was determined by the presence or absence of cataplexy, patients with cataplexy were diagnosed with NT1, and without cataplexy were diagnosed with NT2. We investigated characteristics of the patients, PSG and MSLT outcomes, and applied a suite of duly statistical analysis to account for each parameter. Results Among the 118 subjects, 35 patients (29.7%) were NT1, and 83 patients (70.3%) were NT2. Excessive daytime sleepiness which was measured by Japanese version of Epworth sleepiness scale (JESS) was significantly higher in NT1 than NT2. Furthermore, the presence of sleep hallucination ( n = 29, 82.9%), sleep paralysis ( n = 18, 51.4%), difficult maintaining sleep ( n = 22, 62.9%), and sleep related movement and behavior disorders ( n = 7, 20.0%) were significantly higher in NT1 than those in NT2. Additionally, parameters indicative of sleep fragmentation, such as the arousal index and wake time after sleep onset measured in PSG, exhibited a statistically significant increase in NT1 when contrasted with NT2. Conclusions Fragmentation of nocturnal sleep which is explained by the high arousal index and the long wake time after sleep onset on PSG was considered a characteristic finding of NT1 compared with NT2, and the patients with NT1 experienced greater difficulty of maintaining sleep. Concomitantly, the prevalence of NT1 in this study may be a representative value of the prevalence of NT1 among the patients with narcolepsy in Japan.","PeriodicalId":21632,"journal":{"name":"Sleep Science and Practice","volume":"99 24","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-11-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135092036","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The effect of nutrition and physical activity on sleep quality among adults: a scoping review","authors":"Nawaf W. Alruwaili, Nasser Alqahtani, Maryam H. Alanazi, Bushra S. Alanazi, Meznah S. Aljrbua, Othman M. Gatar","doi":"10.1186/s41606-023-00090-4","DOIUrl":"https://doi.org/10.1186/s41606-023-00090-4","url":null,"abstract":"Abstract Sleep quality and its effects have become a public concern over the last few years. While the prevalence of sleep disorders was increasing, several studies have linked diet and physical activity as a cause of it. Indeed, many people complain about their sleeping problems without considering their lifestyle as a cause. This leads the efforts to focus on these principal factors and find their specific effect. The study aims to map out the research on the effect of nutrition and physical activity on sleep quality. The literature search was conducted in electronic libraries and databases related to nutrition and medical literature – Google Scholar, PubMed, and ScienceDirect– using relevant selected keywords. Article inclusion and selection were made by excluding duplicates, analyzing titles and abstracts, and reviewing the articles’ full text. This review included 61 articles. This literature study reinforces the importance of researching sleep and the lifestyle contributors to poor sleep, such as physical activity and nutrition.","PeriodicalId":21632,"journal":{"name":"Sleep Science and Practice","volume":"67 7","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135510789","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Understanding daytime functioning in insomnia: responder and correlation analyses in patients treated with daridorexant","authors":"Pierre-Philippe Luyet, Antonio Olivieri, Guy Braunstein","doi":"10.1186/s41606-023-00089-x","DOIUrl":"https://doi.org/10.1186/s41606-023-00089-x","url":null,"abstract":"Abstract Background Improving daytime functioning is a key treatment goal for patients with insomnia disorder. In a phase 3 study, using the Insomnia Daytime Symptoms and Impacts Questionnaire (IDSIQ), daridorexant 50 mg significantly improved daytime functioning in adults with insomnia, as well as sleep parameters. These data are further analyzed to evaluate the clinically meaningful changes in IDSIQ scores at weekly intervals and investigate the correlation between the effects of daridorexant on daytime functioning and on sleep quality and quantity. Methods Nine hundred thirty patients with insomnia randomized to daridorexant 25 mg ( n = 310), 50 mg ( n = 310) or placebo ( n = 310) for 12 weeks were analyzed, with focus on daridorexant 50 mg and placebo. Patients recorded daily their daytime functioning using the IDSIQ and their self-reported total sleep time (sTST) and sleep quality using a sleep diary questionnaire; weekly mean changes from baseline were calculated. A clinically meaningful improvement (‘response’) at a given week was defined as a ≥ 20-point decrease in IDSIQ total score from baseline. Results Weekly responder rates increased over time in both groups but were consistently higher each week with daridorexant. Overall, 53% ( n = 165/310) of patients in the daridorexant 50 mg group perceived a response for ≥ 1 week versus 41% in the placebo group ( n = 126/310). This response, which could be achieved at any time during the 12 weeks of the study, was more often continuous on daridorexant and more often intermittent on placebo. Time-to-first response was significantly different between daridorexant and placebo (hazard ratio 1.55; 95% confidence intervals [CI] 1.22, 1.97; p = 0.0003) with shorter time observed in daridorexant. Patient perception of the response also lasted longer on daridorexant than placebo (mean number of continuous responder weeks; 9.2 vs. 7.9 respectively). A decrease in IDSIQ total score was correlated with an increase in sTST and sleep quality and a decrease in morning sleepiness, from Week 1 onwards. Conclusion Patients with insomnia are more likely to perceive a clinically meaningful improvement in their daytime functioning each week with daridorexant 50 mg than placebo. The response, which can fluctuate over time, is also perceived earlier and sustained for longer than placebo. The correlations between improved daytime functioning and improved sleep quantity and quality support the benefits of daridorexant on both the night and daytime symptoms in patients with insomnia disorder. Trial registration ClinicalTrials.gov: NCT03545191.","PeriodicalId":21632,"journal":{"name":"Sleep Science and Practice","volume":"47 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135014223","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Gender differences in obstructive sleep apnea with comorbid treatment-resistant depression","authors":"Emily Kasurak, E. Hawken, D. Kolar, R. Jokic","doi":"10.1186/s41606-023-00087-z","DOIUrl":"https://doi.org/10.1186/s41606-023-00087-z","url":null,"abstract":"","PeriodicalId":21632,"journal":{"name":"Sleep Science and Practice","volume":"24 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-06-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81524273","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Impairment in sleep health in young adults with chronic pain: a modifiable risk factor","authors":"M. Eissa, A. Bhatia, S. Bansal, T. Renna, M. McLoone, J. Stinson, F. Campbell, Stephen D Brown, Sarah Sheffe, Yen Shuang Law, Kawalpreet Singh, Rachael Bosma, Mandeep Singh","doi":"10.1186/s41606-023-00086-0","DOIUrl":"https://doi.org/10.1186/s41606-023-00086-0","url":null,"abstract":"","PeriodicalId":21632,"journal":{"name":"Sleep Science and Practice","volume":"20 1","pages":"1-14"},"PeriodicalIF":0.0,"publicationDate":"2023-05-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80892537","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Sleep as a vital sign","authors":"Matthew E. Hirschtritt, Matthew P. Walker, A. Krystal","doi":"10.1186/s41606-023-00085-1","DOIUrl":"https://doi.org/10.1186/s41606-023-00085-1","url":null,"abstract":"","PeriodicalId":21632,"journal":{"name":"Sleep Science and Practice","volume":"12 1","pages":"1-5"},"PeriodicalIF":0.0,"publicationDate":"2023-04-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73221579","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Clinical application of headache impact test (HIT)-6 and epworth sleepiness scale (ESS) for sleep apnea headache","authors":"Hiromitsu Tabata, M. Kinoshita, M. Taniguchi, Motoharu Ooi","doi":"10.1186/s41606-023-00084-2","DOIUrl":"https://doi.org/10.1186/s41606-023-00084-2","url":null,"abstract":"","PeriodicalId":21632,"journal":{"name":"Sleep Science and Practice","volume":"5 1","pages":"1-9"},"PeriodicalIF":0.0,"publicationDate":"2023-02-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74250688","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"From good sleep to health and to quality of life – a path analysis of determinants of sleep quality of working adults in Abu Dhabi","authors":"M. Badri, Mugheer Alkhaili, Hamad Aldhaheri, Guang Yang, Muna Albahar, Asma Alrashdi","doi":"10.1186/s41606-023-00083-3","DOIUrl":"https://doi.org/10.1186/s41606-023-00083-3","url":null,"abstract":"","PeriodicalId":21632,"journal":{"name":"Sleep Science and Practice","volume":"53 1","pages":"1-13"},"PeriodicalIF":0.0,"publicationDate":"2023-02-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"91358589","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Hyperactivity in patients with narcolepsy and idiopathic hypersomnia: an exploratory study.","authors":"Caroline Dodson,&nbsp;Karen Spruyt,&nbsp;Ciaran Considine,&nbsp;Emily Thompson,&nbsp;Osman S Ipsiroglu,&nbsp;Kanika Bagai,&nbsp;Rosalia Silvestri,&nbsp;Barbara Couvadelli,&nbsp;Arthur S Walters","doi":"10.1186/s41606-023-00088-y","DOIUrl":"https://doi.org/10.1186/s41606-023-00088-y","url":null,"abstract":"<p><strong>Introduction: </strong>Patients with either Idiopathic Hypersomnia or Narcolepsy demonstrate excessive daytime somnolence (EDS) with resultant inattention mimicking Attention Deficit Hyperactivity Disorder (ADHD). Patients with ADHD also often express sleep problems including EDS. Thus, patients with ADHD and patients with idiopathic hypersomnia or narcolepsy may share inattention and daytime drowsiness as common features. However, it is not known whether EDS patients with idiopathic hypersomnia or narcolepsy also have increased movement (hyperactivity) like ADHD patients, the determination of which is the purpose of this study.</p><p><strong>Methods: </strong>We studied 12 patients (7 Narcolepsy type 2 and 5 Idiopathic Hypersomnia) with EDS as shown by Multiple Sleep Latency Test which served as the gold standard for entry into the study. Twelve subjects without symptoms of EDS served as the control group. None of the participants had a previous history of ADHD. Each participant underwent a one-hour session laying at 45 degrees with surveys about the need to move and actigraphy as an objective measure of movement.</p><p><strong>Results: </strong>Sleep-disordered patients with EDS reported more symptoms of inattention and hyperactivity on the ADHD Self-Report Scale. At each of the time points patients with EDS had a clear trend to express the need to move more than controls on the Suggested Immobilization Test (SIT). For the total 60 minutes, a large effect size for the need to move during the SIT test was found between patients and controls (Cohen's <i>d</i> = 0.61, p=0.01). Patients with EDS did not express a need to move more to combat drowsiness than controls, nor did actigraphy show any difference in objective movement between patients and controls during the SIT.</p><p><strong>Conclusion: </strong>Patients with EDS express inattention and a need to move more than controls. However, hyperactivity was not verified by objective measurement, nor did the EDS patients express a need to move to combat drowsiness more than controls. Thus, a hypothesis to be further tested, is whether narcolepsy and idiopathic hypersomnia may be more a model of the inattentive form of ADHD rather than the combined or inattentive/hyperactive form of ADHD. Further studies are needed to explore the relationship between EDS and hyperactivity.</p>","PeriodicalId":21632,"journal":{"name":"Sleep Science and Practice","volume":"7 ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10494784/pdf/nihms-1920946.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10608367","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The relationship between perinatal circadian rhythm and postnatal depression: an overview, hypothesis, and recommendations for practice","authors":"Katherine Hall, Ritaben Patel, J. Evans, R. Greenwood, J. Hicks","doi":"10.1186/s41606-022-00081-x","DOIUrl":"https://doi.org/10.1186/s41606-022-00081-x","url":null,"abstract":"","PeriodicalId":21632,"journal":{"name":"Sleep Science and Practice","volume":"54 1","pages":"1-11"},"PeriodicalIF":0.0,"publicationDate":"2022-12-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90633208","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}