Schmerz最新文献 - Book学术

[Opioid analgesia with oxycodone at the superior cervical ganglion in trigeminal neuralgia]. [三叉神经痛的颈上神经节羟考酮阿片类镇痛]。

IF 0.6 4区医学

Schmerz Pub Date : 2026-05-04 DOI: 10.1007/s00482-026-00938-5

Johannes Westhofen, Habib Bendella, Verena Grüber, Pascal Kowark, Stefan Wirz

引用次数: 0

[Central invasive neuromodulation for the treatment of chronic pain : Epidural motor cortex stimulation and deep brain stimulation]. [中枢侵入性神经调节治疗慢性疼痛：硬膜外运动皮层刺激和深部脑刺激]。

IF 0.6 4区医学

Schmerz Pub Date : 2026-04-30 DOI: 10.1007/s00482-026-00942-9

Volker M Tronnier, Dirk Rasche

{"title":"[Central invasive neuromodulation for the treatment of chronic pain : Epidural motor cortex stimulation and deep brain stimulation].","authors":"Volker M Tronnier, Dirk Rasche","doi":"10.1007/s00482-026-00942-9","DOIUrl":"https://doi.org/10.1007/s00482-026-00942-9","url":null,"abstract":"Background: Treatment of central neuropathic pain, such as pain after plexus avulsion, stroke or cerebral hemorrhage (central post-stroke pain; CPSP) or trigeminal neuropathies, is generally not possible with neuromodulation methods that are carried out further peripherally. Non-invasive neuromodulation methods only have a temporary effect. Permanently implanted electrodes subcortically (deep brain stimulation; DBS) or epi- or subdurally over the motor cortex (\"motor cortex stimulation\", MCS) can lead to pain relief in about 50-70% of patients with central neuropathic pain.Objectives: To present the main indications for DBS and MCS according to the literature.Material and methods: Both procedures, DBS and MCS, are not approved for the treatment of chronic pain, but decades of clinical experiences exist. The results of meaningful studies and clinical series are presented on the basis of a literature search and recommendations for specific indications are developed.Results: Patients with CPSP benefit significantly more from MCS than from DBS, and better results are also achieved with MCS in patients with neuropathic pain after spinal cord injury. Patients with pain after plexus avulsion or phantom pain can be treated better with DBS. The best results are achieved with both procedures in patients with trigeminal neuropathy. We prefer MCS as it is less invasive. The results from both stimulation therapies for postherpetic neuralgia are disappointing.Conclusions: DBS and MCS can be used to treat chronic neuropathic pain when conservative or less invasive measures have failed. Depending on the cause and localization of the pain, DBS or MCS may have better long-term results. However, neither procedure is a \"stand-alone\" therapy; they are additive and must be accompanied by medication and behavioral therapy.","PeriodicalId":21572,"journal":{"name":"Schmerz","volume":" ","pages":""},"PeriodicalIF":0.6,"publicationDate":"2026-04-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147779893","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[Structural and process parameters of interdisciplinary multimodal pain therapy in Germany-an update]. [德国跨学科多模式疼痛治疗的结构和过程参数-更新]。

IF 0.6 4区医学

Schmerz Pub Date : 2026-04-30 DOI: 10.1007/s00482-026-00944-7

R Sabatowski, A Böger, J Lutz, R Scharnagel, B Schönbach

引用次数: 0

[Nocebo effects in the context of visceral pain]. [反安慰剂对内脏疼痛的影响]。

IF 0.6 4区医学

Schmerz Pub Date : 2026-04-20 DOI: 10.1007/s00482-026-00940-x

Karla Großek, Marion Bachmann

引用次数: 0

[Migraine in men: biological, psychosocial and clinical characteristics]. 男性偏头痛：生物学、社会心理和临床特征。

IF 0.6 4区医学

Schmerz Pub Date : 2026-04-17 DOI: 10.1007/s00482-026-00935-8

Carolin Luisa Hoehne, Wiebke Andersen, Bianca Raffaelli

{"title":"[Migraine in men: biological, psychosocial and clinical characteristics].","authors":"Carolin Luisa Hoehne, Wiebke Andersen, Bianca Raffaelli","doi":"10.1007/s00482-026-00935-8","DOIUrl":"https://doi.org/10.1007/s00482-026-00935-8","url":null,"abstract":"Background: Migraine affects 15% of the global population, with men being 2-3 times less frequently affected than women and are markedly underrepresented in research and clinical care. The condition is frequently underdiagnosed in men.Objective: The aim of this work is to describe the biological and psychosocial characteristics of migraine in men in order to improve the understanding of sex-related differences and to enhance the diagnostic precision and treatment for men.Material and methods: This article is a narrative review based on a structured literature search in PubMed using relevant search terms related to migraine and sex differences.Results: Biologically, men differ from women through hormonal influences on the calcitonin gene-related peptide (CGRP), pituitary adenylate cyclase-activating polypeptide (PACAP) and transient receptor potential (TRP) signaling pathways, which modulate pain processing. Clinically, men exhibit on average shorter attacks, lower intensity, more frequently dull-pressing pain and fewer vegetative accompanying symptoms. This presentation often leads to misdiagnosis. Additionally, role expectations, stigma and lower help-seeking behavior contribute to symptoms being reported later and underestimated more often. Although modern therapies are similarly effective in both sexes, men receive prophylactic treatment less frequently.Conclusion: The sex-specific biological and psychosocial differences demonstrate that men present with a distinct clinical phenotype of migraine. Greater awareness with respect to these characteristics could enhance the diagnostic accuracy and support more individualized treatment.","PeriodicalId":21572,"journal":{"name":"Schmerz","volume":" ","pages":""},"PeriodicalIF":0.6,"publicationDate":"2026-04-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147717891","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[Pain and fatigue therapy in children and adolescents (SHARK): care model and initial evaluation results]. 儿童和青少年疼痛和疲劳治疗（SHARK）：护理模式和初步评价结果。

IF 0.6 4区医学

Schmerz Pub Date : 2026-04-15 DOI: 10.1007/s00482-026-00937-6

Lea Höfel, B Lampert, J-P Haas

引用次数: 0

[Peripheral nerve stimulation-A new perspective in surgical pain treatment]. 外周神经刺激——外科疼痛治疗的新视角。

IF 0.6 4区医学

Schmerz Pub Date : 2026-04-02 DOI: 10.1007/s00482-026-00933-w

Ute Bäzner, Rezvan Ahmadi

{"title":"[Peripheral nerve stimulation-A new perspective in surgical pain treatment].","authors":"Ute Bäzner, Rezvan Ahmadi","doi":"10.1007/s00482-026-00933-w","DOIUrl":"https://doi.org/10.1007/s00482-026-00933-w","url":null,"abstract":"Background: Peripheral nerve stimulation (PNS) has been a part of neuromodulation for decades. New systems and advancements have the potential to bring renewed focus to this subfield and alter the risk profile for patients.Objective: To illustrate the mechanism of action, present stimulation options and areas of application and explore future perspectives.Material and methods: Description and discussion of current options and systems for PNS based on the literature.Results: The PNS is a targeted and straightforward method for treating certain pain syndromes. New stimulation parameters and modalities as well as the use of newly developed wireless systems or specially designed devices with very small pulse generators offer new possibilities in this area.Conclusion: Direct stimulation of the affected nerve can provide an individually tailored solution for patients. New systems and stimulation modalities constitute a milestone in this subfield of neuromodulation. Overcoming the limitations of older technologies leads to improved patient safety and comfort. As such, PNS can become an important cornerstone in the treatment of chronic pain.","PeriodicalId":21572,"journal":{"name":"Schmerz","volume":" ","pages":""},"PeriodicalIF":0.6,"publicationDate":"2026-04-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147594428","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[Impulse for a sustainable pain treatment: think interprofessionally, make the next generation visible]. [推动可持续的疼痛治疗：跨专业思考，让下一代可见]。

IF 0.6 4区医学

Schmerz Pub Date : 2026-04-01 Epub Date: 2026-03-20 DOI: 10.1007/s00482-026-00927-8

Sebastian Pantke, Nils Reiter, Melina Hendlmeier

引用次数: 0

[The implementation of an adaptive multimodal interdisciplinary pain therapy exemplified by a medical care center (MVZ) structure in Dresden]. [以德累斯顿医疗中心（MVZ）结构为例，实施适应性多模式跨学科疼痛治疗]。

IF 0.6 4区医学

Schmerz Pub Date : 2026-04-01 DOI: 10.1007/s00482-026-00936-7

B Schönbach, T Kupke, U Ludwig, R Scharnagel, R Sabatowski

{"title":"[The implementation of an adaptive multimodal interdisciplinary pain therapy exemplified by a medical care center (MVZ) structure in Dresden].","authors":"B Schönbach, T Kupke, U Ludwig, R Scharnagel, R Sabatowski","doi":"10.1007/s00482-026-00936-7","DOIUrl":"https://doi.org/10.1007/s00482-026-00936-7","url":null,"abstract":"Chronic pain is characterized by high and increasing prevalences and is associated with significant functional impairments and substantial healthcare costs. Qualitative and quantitative gaps in patient care are manifested as patient dissatisfaction, increased follow-up costs and the promotion of further chronification processes. Interdisciplinary multimodal pain therapy considers the underlying biopsychosocial factors of chronic pain conditions and is considered the evidence-based gold standard of treatment. Corresponding treatment approaches are time-consuming and personnel-intensive and are predominantly available in (partial) inpatient settings within standard care. Therefore, suitable care structures are needed for outpatient care that are based on the concept of interdisciplinary multimodal pain therapy and enable targeted treatment. To date, such approaches have primarily been implemented within the framework of pilot projects and selective contracts. Significant obstacles include inadequate reimbursement and billing options within the standardized fee schedule, which do not adequately reflect interdisciplinary collaboration. Using the example of a medical care center (MVZ) structure, a model for adaptive, multimodal, interdisciplinary pain therapy is presented. This model addresses the complex treatment requirements of chronic pain patients, enables the needs-based allocation of personnel resources and promotes structured collaboration among the participating medical disciplines. A central element is a diagnostic and therapeutic process that is continuously optimized through feedback loops, in which multimodal therapy elements are coordinated across disciplines and linked via shared digital files and case discussions.","PeriodicalId":21572,"journal":{"name":"Schmerz","volume":" ","pages":""},"PeriodicalIF":0.6,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147594480","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[The Cluster Headache Impact Questionnaire : Measuring headache-related impairment in cluster headache patients]. 丛集性头痛影响问卷：测量丛集性头痛患者的头痛相关损害。

IF 0.6 4区医学

Schmerz Pub Date : 2026-04-01 Epub Date: 2025-01-23 DOI: 10.1007/s00482-024-00859-1

Katharina Kamm, Andreas Straube, Ruth Ruscheweyh

{"title":"[The Cluster Headache Impact Questionnaire : Measuring headache-related impairment in cluster headache patients].","authors":"Katharina Kamm, Andreas Straube, Ruth Ruscheweyh","doi":"10.1007/s00482-024-00859-1","DOIUrl":"10.1007/s00482-024-00859-1","url":null,"abstract":"Cluster headache is a severe primary headache disorder, which can be associated with a substantial impairment for sufferers. The Cluster Headache Impact Questionnaire (CHIQ) is a short questionnaire for measuring the cluster headache-specific impairment. A 5-stage severity grading from \"no to low impairment\" to \"'extreme impairment\" was established based on the results of an English-speaking patient collective. The present article tested whether the severity classification can be transferred to a German patient group. Data from 196 patients with episodic and chronic cluster headache were examined during an active episode. The severity grading classification of the CHIQ also showed clinically relevant results in the German collective, i.e., the five degrees of severity showed significant differences with respect to attack frequency, intake of acute medication and unspecific headache-related impairment (HIT-6) and quality of life (SF-12v2). Interestingly, 32 out of 52 patients with episodic cluster headache outside the active epísode suffered an impairment above the lowest severity grade, i.e., at least a moderate impairment. In conclusion, the CHIQ provides a short instrument to document the current impairment in cluster headache patients. The severity grading classification presented here facilitates the clinical interpretation.","PeriodicalId":21572,"journal":{"name":"Schmerz","volume":" ","pages":"96-104"},"PeriodicalIF":0.6,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13004745/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143024682","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0