Rossiyskiy Vestnik Perinatologii i Pediatrii (Russian Bulletin of Perinatology and Pediatrics)最新文献_第6页

Features of dental status in children with autistic disorders 自闭症儿童牙齿状况的特点

Rossiyskiy Vestnik Perinatologii i Pediatrii (Russian Bulletin of Perinatology and Pediatrics) Pub Date : 2024-01-12 DOI: 10.21508/1027-4065-2023-68-6-61-66

A. I. Krapivkin, E. E. Yatskevich, K. V. Osipova

{"title":"Features of dental status in children with autistic disorders","authors":"A. I. Krapivkin, E. E. Yatskevich, K. V. Osipova","doi":"10.21508/1027-4065-2023-68-6-61-66","DOIUrl":"https://doi.org/10.21508/1027-4065-2023-68-6-61-66","url":null,"abstract":"Purpose. The purpose of the publication was to conduct an epidemiological survey for a comprehensive study of the dental status in children with autism spectrum disorder to clarify the areas of medical and social work and the potential scope of dental intervention.Materials and Methods. We examined 98 children with autism spectrum disorders aged 3 to 7 years, 69 of them with temporary and 29 with mixed occlusion. A dental examination of patients was carried out, the state of oral hygiene, carious defects of the teeth, and the state of periodontal tissues were assessed. Results. It is shown that the state of oral hygiene in children with autism spectrum disorder is unsatisfactory. The need for dental care in 85±5.6% of patients was diagnosed; there was a high prevalence (78.6%) of caries of primary teeth against the background of a significant intensity of caries pathology (the share of the “D” component in the overall structure of caries intensity is 81±3.11%); The prevalence of gingivitis was 61%, and the proportion of children with healthy parodontium was 7.14%.Conclusion. The results of the study determine the need to provide children with autism spectrum disorders with qualified dental care and its significant volumes. A set of recommended therapeutic and preventive measures has been proposed, including strengthening oral hygiene with particular regard to the specific characteristics of the underlying disease (emphasis on the motivational factor, transferring manual actions to a game format, using gadgets), strengthening pathogenetic therapy with the daily use of remineralizing drugs, the use of special physical therapeutic techniques (programs) in combination with regular examinations at the dentist and an increase in the intensity of preventive measures.","PeriodicalId":21550,"journal":{"name":"Rossiyskiy Vestnik Perinatologii i Pediatrii (Russian Bulletin of Perinatology and Pediatrics)","volume":"56 28","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-01-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139533098","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Anti-relapse therapy in children with chronic secondary pyelonephritis: evaluation of effectiveness and rationale for a differentiated approach 慢性继发性肾盂肾炎患儿的抗复发治疗：疗效评估和采用不同方法的理由

Rossiyskiy Vestnik Perinatologii i Pediatrii (Russian Bulletin of Perinatology and Pediatrics) Pub Date : 2024-01-12 DOI: 10.21508/1027-4065-2023-68-6-41-49

A. Eremeeva, V. Dlin

{"title":"Anti-relapse therapy in children with chronic secondary pyelonephritis: evaluation of effectiveness and rationale for a differentiated approach","authors":"A. Eremeeva, V. Dlin","doi":"10.21508/1027-4065-2023-68-6-41-49","DOIUrl":"https://doi.org/10.21508/1027-4065-2023-68-6-41-49","url":null,"abstract":"Currently, there is no unified system of anti-relapse treatment of pyelonephritis in children.Purpose. To assess the feasibility of prescribing and effectiveness of various anti-relapse therapy regimens to prevent exacerbations of the disease in children with chronic secondary pyelonephritis.Materials and Methods. The study involved 158 children with chronic secondary pyelonephritis aged 2 to 14 years, including 130 (82.3%) girls and 28 boys (17.7%). The children were divided into the following groups: Group A (n=32) — furazidine — 14 days, anti-relapse therapy after 12 months; Group B (n=34) — furazidine — 14 days, then — Canephron 1 month, anti–relapse therapy after 12 months; Group C (n=34) — Canephron 3 months, anti-relapse therapy after 12 months; Group D (n=30) — furazidine — 14 days, then — Canephron 1 month of anti–relapse therapy after 6 months; Group E (n=28) — furazidine — 14 days of anti-relapse therapy was not performed. Results. It was found that the recurrence rate of chronic secondary pyelonephritis for a 24-month follow-up in Group A was 28.1% (n=9), in Group B, 14.7% (n=5), in Group C, 20.5% (n=7), in Group D, 10% (n=3), in Group E, 42.9% (n=12). The timing of relapse of chronic secondary pyelonephritis was different, with the largest increase in the proportion of patients with exacerbations in the period from 6 to 12 months. The average recurrence rate per year in the catamnesis in all children (n=158) was 1.4 [1.2–1.6], during the prospective follow-up, a statistically significant (p=0.001) decrease in the recurrence rate to 0.36 [0.2–0.79] was noted. Conclusion. The data obtained confirm the feasibility of anti-relapse therapy in children with chronic secondary pyelonephritis.","PeriodicalId":21550,"journal":{"name":"Rossiyskiy Vestnik Perinatologii i Pediatrii (Russian Bulletin of Perinatology and Pediatrics)","volume":"5 12","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-01-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139532511","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Early diagnosis of acute kidney injury in children with poisoning of chemical etiology 儿童化学中毒急性肾损伤的早期诊断

Rossiyskiy Vestnik Perinatologii i Pediatrii (Russian Bulletin of Perinatology and Pediatrics) Pub Date : 2024-01-12 DOI: 10.21508/1027-4065-2023-68-6-50-60

O. Chugunova, S. B. Amergulova, L. A. Kovalenko, L. A. Sukhodolova, O. I. Yaroshevskaya, V. Dlin, P. Shumilov

{"title":"Early diagnosis of acute kidney injury in children with poisoning of chemical etiology","authors":"O. Chugunova, S. B. Amergulova, L. A. Kovalenko, L. A. Sukhodolova, O. I. Yaroshevskaya, V. Dlin, P. Shumilov","doi":"10.21508/1027-4065-2023-68-6-50-60","DOIUrl":"https://doi.org/10.21508/1027-4065-2023-68-6-50-60","url":null,"abstract":"Purpose. The study aims at optimizing the diagnosis of acute kidney injury in children with poisoning of chemical etiology based on the use of early markers of kidney damage.Materials and Methods. The study enrolled 120 patients aged 1–18 years with poisoning of chemical etiology. Routine methods of kidney function estimation were supplemented by an investigation of urinary concentration of acute kidney injury early markers: lipocalin-2, kidney injury molecule-1. All children were hospitalized in a toxicology unit on the 1st day after exposure to toxic substance. Twenty practically healthy children aged 1–18 years were examined as control group.Results. Only one patient (0.8%) had acute kidney injury determined as increased serum creatinine at the time of admission, but at the same time 35 children (29.2%) had increased levels of one or more urinary markers. By the 3rd day 32 of those 35 children with increased urinary markers developed acute kidney injury stages 1 or 2, determined as significant rise of serum creatinine and decrease of renal blood flow according to Doppler ultrasound. On the contrary, no patient with initially normal level of urinary markers developed acute kidney injury. Thus, 32/120 patients hospitalized with poisoning of chemical etiology, developed acute kidney injury (26.7%).Conclusion. Increased urinary excretion of lipocalin-2 and kidney injury molecule-1 at the first day of acute chemical poisoning can be estimated as predictive marker of acute kidney injury development.","PeriodicalId":21550,"journal":{"name":"Rossiyskiy Vestnik Perinatologii i Pediatrii (Russian Bulletin of Perinatology and Pediatrics)","volume":"19 9","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-01-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139532616","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Tolerance and taste perception of goat milk-based original complementary food products: results of a multicenter clinical study 对羊奶原辅食品的耐受性和味觉感知：一项多中心临床研究的结果

Rossiyskiy Vestnik Perinatologii i Pediatrii (Russian Bulletin of Perinatology and Pediatrics) Pub Date : 2024-01-12 DOI: 10.21508/1027-4065-2023-68-6-75-84

V. P. Novikova, A. N. Zavyalova, A. L. Balashov, T. Malanicheva, I. Churakova, S. B. Samigullina

{"title":"Tolerance and taste perception of goat milk-based original complementary food products: results of a multicenter clinical study","authors":"V. P. Novikova, A. N. Zavyalova, A. L. Balashov, T. Malanicheva, I. Churakova, S. B. Samigullina","doi":"10.21508/1027-4065-2023-68-6-75-84","DOIUrl":"https://doi.org/10.21508/1027-4065-2023-68-6-75-84","url":null,"abstract":"The formation of taste preferences and diversity of a child’s diet, as well as the prevention of neophobia, are relevant and discussed issues in clinical practice and scientific literature. A group of authors from St. Petersburg and Kazan conducted a multicenter clinical study to study both food tolerance and taste perception of two complementary feeding products based on goat milk (vegetable and vegetable-grain). We studied eating behavior using a questionnaire and physical development in 92 healthy children aged 8 to 11 months. Statistical processing of the material was carried out using the IBM Stata 12 application package. The assessment of food tolerance showed good results for all products studied. The physical development of children in both regions met the standards both at the beginning of testing and at the end. At the same time, taste perception had regional characteristics, depended on the place of residence of the children and, probably, on the mother’s food preferences during pregnancy for a variety of vegetable and vegetable-grain components of dishes. It should be taken into account when expanding the infant’s diet.","PeriodicalId":21550,"journal":{"name":"Rossiyskiy Vestnik Perinatologii i Pediatrii (Russian Bulletin of Perinatology and Pediatrics)","volume":"20 9","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-01-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139532606","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Genetic aspects of the development of congenital anomalies of the kidney and urinary tract 肾脏和泌尿道先天性异常发育的遗传因素

Rossiyskiy Vestnik Perinatologii i Pediatrii (Russian Bulletin of Perinatology and Pediatrics) Pub Date : 2024-01-10 DOI: 10.21508/1027-4065-2023-68-6-15-23

T. S. Kursova, S. L. Morozov, S. V. Baiko, V. Dlin

{"title":"Genetic aspects of the development of congenital anomalies of the kidney and urinary tract","authors":"T. S. Kursova, S. L. Morozov, S. V. Baiko, V. Dlin","doi":"10.21508/1027-4065-2023-68-6-15-23","DOIUrl":"https://doi.org/10.21508/1027-4065-2023-68-6-15-23","url":null,"abstract":"Congenital anomalies of the kidney and urinary tract (CAKUT) include a wide range of structural anomalies that develop as a result of impaired morphogenesis of the kidneys and/or urinary tract. CAKUT accounts for about 40–50% of patients under 21 with chronic kidney disease worldwide. Most congenital anomalies of the urinary system are diagnosed in utero or during the first months of a child’s life, which determines further tactics for managing a child, depending on the severity of CAKUT and the degree of decrease in the filtration function of the kidneys. The article provides modern data on the causes of the development of anomalies of the urinary system, provides examples of the development of scientific areas that will be aimed at predicting the occurrence of malformations. In addition, early markers of the disease are considered. Thus, the problem of anomalies of the urinary system remains relevant to the present despite the significant contribution of genetics to understanding the pathogenesis and predicting the development of CAKUT.","PeriodicalId":21550,"journal":{"name":"Rossiyskiy Vestnik Perinatologii i Pediatrii (Russian Bulletin of Perinatology and Pediatrics)","volume":"60 42","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-01-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139534870","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Autoimmune gastritis in children 儿童自身免疫性胃炎

Rossiyskiy Vestnik Perinatologii i Pediatrii (Russian Bulletin of Perinatology and Pediatrics) Pub Date : 2024-01-10 DOI: 10.21508/1027-4065-2023-68-6-5-14

G. Volynets, A. I. Khavkin, A. Potapov, A. Nikitin

{"title":"Autoimmune gastritis in children","authors":"G. Volynets, A. I. Khavkin, A. Potapov, A. Nikitin","doi":"10.21508/1027-4065-2023-68-6-5-14","DOIUrl":"https://doi.org/10.21508/1027-4065-2023-68-6-5-14","url":null,"abstract":"Etiology of autoimmune gastritis, particularly in children, is still unknown. However, the role of Helicobacter pylori and Epstein–Barr virus in the development of autoimmune gastritis is being considered. The formation of autoimmune gastritis is based on an autoimmune reaction mediated by CD4+ T-lymphocytes and the formation of antibodies to gastric parietal cells, the target of which is gastric Н+/К+-АТPase, with subsequent destruction of parietal cells and the development of mucosal atrophy. Autoimmune gastritis is considered a precancerous condition. The clinical picture of autoimmune gastritis in children is not associated with any specific symptoms of the digestive organs. Abdominal pain is uncommon. Specific manifestations of a dyspeptic nature are rare. Often there is a syndrome of chronic nonspecific intoxication. Red blood counts in most children with autoimmune gastritis are within the age norm. Iron deficiency anemia occurs in 13.8% of patients. Vitamin B12 deficiency anemia does not occur in children. Autoantibodies to the parietal cells of the stomach are considered to be a serum marker and diagnostic criterion for autoimmune gastritis in children. Treatment of autoimmune gastritis is aimed at preventing iron and/or vitamin B12 deficiency. No specific methods of treatment have been developed so far. Conclusion. The incidence of autoimmune gastritis in children is underestimated. The role of Helicobacter pylori in autoimmune gastritis has not been confirmed. There is a close correlation of antibodies to gastric parietal cells with Epstein–Barr viral DNA. Due to adverse outcomes and the risk of malignancy, early diagnosis of the disease is important. Atrophic gastritis and intestinal metaplasia are precancerous conditions, although extremely rare in childhood, they should not be neglected.","PeriodicalId":21550,"journal":{"name":"Rossiyskiy Vestnik Perinatologii i Pediatrii (Russian Bulletin of Perinatology and Pediatrics)","volume":"59 10","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-01-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139534931","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Recurrent eosinophilic esophagitis in an adolescent patient 一名青少年患者的复发性嗜酸性粒细胞食管炎

Rossiyskiy Vestnik Perinatologii i Pediatrii (Russian Bulletin of Perinatology and Pediatrics) Pub Date : 2023-11-16 DOI: 10.21508/1027-4065-2023-68-5-126-130

R. Khakimova, A. Kamalova, Yu. M. Akhmatova, D. E. Tarasova, N. S. Poliakov, A. R. Khabibullina, A. G. Kuznetsova

引用次数: 0

Sarcopenic obesity in a child with type IXa glycogenosis in combination with eosinophilic esophagitis and Legg–Calvé–Perthes disease 一名 IXa 型糖原中毒合并嗜酸性粒细胞食管炎和莱格-卡尔维-珀特氏病的患儿出现肉质疏松性肥胖症

Rossiyskiy Vestnik Perinatologii i Pediatrii (Russian Bulletin of Perinatology and Pediatrics) Pub Date : 2023-11-16 DOI: 10.21508/1027-4065-2023-68-5-89-94

A. V. Ishbuldina, R. Rakhmaeva, A. Kamalova, D. V. Usova, A. M. Khazieva, A. M. Nigmatullina, M. S. Zainetdinova

引用次数: 0

Fecal calprotectin as a marker of inflammatory bowel diseases 作为炎症性肠病标志物的粪便钙蛋白

Rossiyskiy Vestnik Perinatologii i Pediatrii (Russian Bulletin of Perinatology and Pediatrics) Pub Date : 2023-11-16 DOI: 10.21508/1027-4065-2023-68-5-138-143

A. Kamalova, G. A. Garina, I. K. Valeeva, A. Gaifutdinova

{"title":"Fecal calprotectin as a marker of inflammatory bowel diseases","authors":"A. Kamalova, G. A. Garina, I. K. Valeeva, A. Gaifutdinova","doi":"10.21508/1027-4065-2023-68-5-138-143","DOIUrl":"https://doi.org/10.21508/1027-4065-2023-68-5-138-143","url":null,"abstract":"Calprotectin is a calcium- and zinc-binding protein belonging to the S100 protein family. This protein is found mainly in the cytoplasm of neutrophils, and, to a lesser extent, in monocytes and macrophages, which can be found in any human organs, but mainly in blood, cerebrospinal fluid, feces, saliva, and synovial fluid. Calprotectin is an effective tool forthe differential diagnosis of inflammatory bowel disease (IBD) and irritable bowel syndrome (IBS). There is a connection of fecal calprotectin (FC) with the endoscopic activity of IBD, however, the available literature shows significant differences in the sensitivity and specificity of FC for predicting the endoscopic activity of the disease. In addition, FC can be considered as a predictor of histological mucosal healing and as a marker for assessing the response to treatment, including surgical, but there is still no consensus on the threshold value of a biomarker for these purposes. Conflicting data are presented in reports on FC as a predictor of IBD recurrence. FC seems to be effective for detecting relapse, however, there is no specific threshold value, therefore, the marker cannot completely replace endoscopic examination methods. In addition, there is intraindividual variability in the concentration of FC in patients, depending on age, type of feeding in the first year of life, taking medications, which significantly complicates the interpretation of the results.","PeriodicalId":21550,"journal":{"name":"Rossiyskiy Vestnik Perinatologii i Pediatrii (Russian Bulletin of Perinatology and Pediatrics)","volume":"89 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-11-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139270513","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Diagnostic problems in pediatrics on the example of a clinical case of neuroblastoma 以神经母细胞瘤临床病例为例分析儿科诊断问题

Rossiyskiy Vestnik Perinatologii i Pediatrii (Russian Bulletin of Perinatology and Pediatrics) Pub Date : 2023-11-16 DOI: 10.21508/1027-4065-2023-68-5-131-134

E. A. Kurmaeva, G. A. Kulakova, N. A. Solovieva, S. Y. Volgina, R. V. Ivanov

引用次数: 0