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ECG beat classification using discrete wavelet coefficients 利用离散小波系数进行心电图搏动分类
2010 5th International Symposium on Health Informatics and Bioinformatics Pub Date : 2010-04-20 DOI: 10.1109/HIBIT.2010.5478916
A. Adib, M. Haque
{"title":"ECG beat classification using discrete wavelet coefficients","authors":"A. Adib, M. Haque","doi":"10.1109/HIBIT.2010.5478916","DOIUrl":"https://doi.org/10.1109/HIBIT.2010.5478916","url":null,"abstract":"In this work we have developed a new approach to identify different types of electrocardiogram (ECG) beats using discrete wavelet transform (DWT) coefficients. The purpose of the study is to develop a simple algorithm for the diagnosis of some cardiac abnormalities. Five types of cardiac phenomena are considered and for each of these some particular records from the MIT-BIH Arrhythmia Database are selected. For these records DWT coefficients up to level 4 are calculated in the Matlab 7.4.0 environment, using different types of mother wavelets. The maximum value of the approximation coefficients of level 4 is selected as the indicating parameter, which is used to distinguish between different abnormalities. A comparison is made between the performances of different types of mother wavelets to select the mother wavelet providing the best result.","PeriodicalId":215457,"journal":{"name":"2010 5th International Symposium on Health Informatics and Bioinformatics","volume":"11 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2010-04-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126842525","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 4
Functional near infrared spectroscopy based congitive task classification using support vector machines 基于功能近红外光谱的支持向量机认知任务分类
2010 5th International Symposium on Health Informatics and Bioinformatics Pub Date : 2010-04-20 DOI: 10.1109/HIBIT.2010.5478913
B. Abibullaev, Won-Seok Kang, Seung Hyun Lee, J. An
{"title":"Functional near infrared spectroscopy based congitive task classification using support vector machines","authors":"B. Abibullaev, Won-Seok Kang, Seung Hyun Lee, J. An","doi":"10.1109/HIBIT.2010.5478913","DOIUrl":"https://doi.org/10.1109/HIBIT.2010.5478913","url":null,"abstract":"the present study analyzes brain hemodynamic concentration of frontal cortex during four cognitive mental tasks. The analysis procedure consists of three sequential steps. First, the strong brain activation regions have been investigated thoroughly from all subjects in order to find a proper electrode location that generates important brain stimuli. Second, a feature extraction method that is based on wavelet transforms and denoising technique for extraction of important task-relevant features. Finally, support vector machines have been using in the classification of mental tasks with wavelet input coefficients. By applying the methodology for 4-subjects in average we achieved 92 % classification rates. However, the results depend on the type of the task that subject were performing. It is expect that the proposed method can be a basic technology for brain-computer interface by combining wavelets with support vector machines.","PeriodicalId":215457,"journal":{"name":"2010 5th International Symposium on Health Informatics and Bioinformatics","volume":"11 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2010-04-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129287202","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Structural properties of hub proteins 枢纽蛋白的结构特性
2010 5th International Symposium on Health Informatics and Bioinformatics Pub Date : 2010-04-20 DOI: 10.1109/HIBIT.2010.5478881
Engin Cukuroglu, Elif Ozkirimli, O. Keskin
{"title":"Structural properties of hub proteins","authors":"Engin Cukuroglu, Elif Ozkirimli, O. Keskin","doi":"10.1109/HIBIT.2010.5478881","DOIUrl":"https://doi.org/10.1109/HIBIT.2010.5478881","url":null,"abstract":"Protein-protein interaction networks are scale free networks with a few hub proteins that have many interaction partners in the network. In this work, we examined the flexibility of the hubs by using a structural perspective and compared date hubs, which bind their partners at different times, and party hubs, which bind their partners simultaneously, with non hub proteins. The flexibility of the proteins is evaluated using temperature factors. Party hubs are found to be more flexible than date hubs, which in turn are more flexible than non-hub proteins. These may explain how a hub interacts with its partners specifically.","PeriodicalId":215457,"journal":{"name":"2010 5th International Symposium on Health Informatics and Bioinformatics","volume":"30 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2010-04-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114520624","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
Turkish Aeromedical Center 土耳其航空医疗中心
2010 5th International Symposium on Health Informatics and Bioinformatics Pub Date : 2010-04-20 DOI: 10.1109/HIBIT.2010.5478905
Erdinç Ercan, N. Ata, Zeki Dulkadir, Yusuf Ersal, A. Akın
{"title":"Turkish Aeromedical Center","authors":"Erdinç Ercan, N. Ata, Zeki Dulkadir, Yusuf Ersal, A. Akın","doi":"10.1109/HIBIT.2010.5478905","DOIUrl":"https://doi.org/10.1109/HIBIT.2010.5478905","url":null,"abstract":"Eskisehir Military Hospital makes aircrew's periodic health examinations annually and five yearly. And Aircrew's Health Research and Training Center give physiological trainings to aircrew five yearly. Physiological Training is necessary, because; pilots who are knowledgeable about physiological phenomena encountered in the aviation environment are better prepared to deal with such potentially fatal in-flight events. In our center we have six physiological training devices; Hypobaric Chamber (Altitude Chamber), Spatial Disorientation Training Device, Human Centrifuge, Night Vision Trainer, Ejection Seat Trainer, Hyperbaric Chamber. Turkish Aeromedical Center's goal is to achieve an advanced level in physiological training of aircrew and to keep this acquired behavior for future flight safety. Our objectives are; to keep the details of academical training up to date and to upgrade the physiological training devices according to the need of aviation and changing technology.","PeriodicalId":215457,"journal":{"name":"2010 5th International Symposium on Health Informatics and Bioinformatics","volume":"41 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2010-04-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133521105","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Computational analysis of the binding free energy of H3K9me3 peptide to the tandem tudor domains of JMJD2A H3K9me3肽与JMJD2A串联tudor结构域结合自由能的计算分析
2010 5th International Symposium on Health Informatics and Bioinformatics Pub Date : 2010-04-20 DOI: 10.1109/HIBIT.2010.5478901
Musa Ozboyaci, O. Keskin, B. Erman, A. Gursoy
{"title":"Computational analysis of the binding free energy of H3K9me3 peptide to the tandem tudor domains of JMJD2A","authors":"Musa Ozboyaci, O. Keskin, B. Erman, A. Gursoy","doi":"10.1109/HIBIT.2010.5478901","DOIUrl":"https://doi.org/10.1109/HIBIT.2010.5478901","url":null,"abstract":"JMJD2A is a histone lysine demethylase enzyme which plays a prominent role in the development of prostate and esophageal squamous cancers. Consisting of a JmjC, a JmjN, two PHD and two tandem tudor domains, JMJD2A recognizes and binds to four different methylated histone peptides: H3K4me3, H4K20me3, H4K20me2 and H3K9me3, via its tudor domains. Of the four histone peptides, only recognition of the H3K4me3 and H4K20me3 by JMJD2A-tudor has been identified. In this study, we investigated the recognition of trimethylated H3K9 by the tandem tudor domains of JMJD2A. Using the molecular dynamics simulations, we performed normal mode and molecular mechanics - Poisson Boltzmann / generalized born - surface area (MM-PB/GB-SA) analysis to find the entropic and enthalpic contributions to binding free energy respectively. We showed that binding of the ligand is mainly driven by favorable van der Waals interactions made after complexation. Our findings suggest that, upon complex formation, H3K9me3 peptide adopts a similar binding mode and the same orientation with H3K4me3 peptide.","PeriodicalId":215457,"journal":{"name":"2010 5th International Symposium on Health Informatics and Bioinformatics","volume":"17 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2010-04-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130097973","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Interpolation approaches and spline based resampling for MR images 磁共振图像的插值方法和基于样条的重采样
2010 5th International Symposium on Health Informatics and Bioinformatics Pub Date : 2010-04-20 DOI: 10.1109/HIBIT.2010.5478891
Evgin Göçeri, N. Loménie
{"title":"Interpolation approaches and spline based resampling for MR images","authors":"Evgin Göçeri, N. Loménie","doi":"10.1109/HIBIT.2010.5478891","DOIUrl":"https://doi.org/10.1109/HIBIT.2010.5478891","url":null,"abstract":"2D or 3D dataset transformations, interpolations and resampling operations are essential techniques that are able to display graphical models in several fields such as medical visualization and engineering. In this study, an overview of interpolation approaches of the last ten years was given and a resampling application for magnetic resonance images was implemented using free form cubic b-spline deformation model based transformed images. In addition, the registration error was shown as a grid view for the 2D nonrigid registration.","PeriodicalId":215457,"journal":{"name":"2010 5th International Symposium on Health Informatics and Bioinformatics","volume":"20 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2010-04-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125628333","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 4
Classification of EEG signals in four groups, including healthy subjects with open/closed eyes and epilepsy subjects with/without seizure by PSD estimate (using the multitaper method) and ANN 采用PSD估计(多锥度法)和人工神经网络对健康睁眼/闭眼者和癫痫发作/不发作者的脑电图信号进行分类
2010 5th International Symposium on Health Informatics and Bioinformatics Pub Date : 2010-04-20 DOI: 10.1109/HIBIT.2010.5478900
Masoud Alipoor, M. Pooyan, A. Suratgar
{"title":"Classification of EEG signals in four groups, including healthy subjects with open/closed eyes and epilepsy subjects with/without seizure by PSD estimate (using the multitaper method) and ANN","authors":"Masoud Alipoor, M. Pooyan, A. Suratgar","doi":"10.1109/HIBIT.2010.5478900","DOIUrl":"https://doi.org/10.1109/HIBIT.2010.5478900","url":null,"abstract":"Electroencephalography (EEG) analysis by physicians is intricate, time consuming and needs to experience. Therefore automated systems for EEG analysis and classification are able to help physician. EEG signal in the field of time is raw and complex so it's not suitable for automated system. Therefore appropriate features of EEG signal becomes extraction using signal processing methods (in this paper used Thomson multi taper method's (MTM)), then these features becomes classification by ANN. Also we have to correct the ANN outputs by a threshold function. In this study, EEG signals are classified in three groups (including epileptic patients with seizure or without seizure and healthy volunteers) with 98.02% accuracy and in two groups (healthy with closed or open eyes) with 97.7% accuracy.","PeriodicalId":215457,"journal":{"name":"2010 5th International Symposium on Health Informatics and Bioinformatics","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2010-04-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131864144","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 14
Systematic computational analysis of potential RNAi regulation in Toxoplasma gondii 刚地弓形虫潜在RNAi调控的系统计算分析
2010 5th International Symposium on Health Informatics and Bioinformatics Pub Date : 2010-04-20 DOI: 10.1109/HIBIT.2010.5478909
M. V. Çakir, J. Allmer
{"title":"Systematic computational analysis of potential RNAi regulation in Toxoplasma gondii","authors":"M. V. Çakir, J. Allmer","doi":"10.1109/HIBIT.2010.5478909","DOIUrl":"https://doi.org/10.1109/HIBIT.2010.5478909","url":null,"abstract":"RNA interference (RNAi) is the mechanism through which RNA interferes with the production of other RNAs in a sequence specific manner. Micro RNA (miRNA) is a type of RNA which is transcribed as pri-miRNAs and processed to pre-miRNAs in the nucleus. These pre-miRNAs are then exported from the nucleus and processed in the cytoplasm to double stranded RNA with one strand providing target specificity..Toxoplasma gondii is a parasitic apicomplexan which causes several diseases. T. gondii is a good candidate for computational efforts with its small and publicly available genome files and extensive information about its gene structure. Although the existence of RNA interference in T. gondii is being debated, establishment of its complete potential RNAi regulatory network may be beneficial for further investigations into the topic.","PeriodicalId":215457,"journal":{"name":"2010 5th International Symposium on Health Informatics and Bioinformatics","volume":"26 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2010-04-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129216711","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 25
Investigation of TEM-1 and SHV-1 beta-lactamase ligand binding TEM-1与SHV-1 β -内酰胺酶配体结合的研究
2010 5th International Symposium on Health Informatics and Bioinformatics Pub Date : 2010-04-20 DOI: 10.1109/HIBIT.2010.5478885
Pinar Kanlikilicer, Elif Özkirimli Ölmez, Nilay Büdeyri̇, B. S. Akbulut
{"title":"Investigation of TEM-1 and SHV-1 beta-lactamase ligand binding","authors":"Pinar Kanlikilicer, Elif Özkirimli Ölmez, Nilay Büdeyri̇, B. S. Akbulut","doi":"10.1109/HIBIT.2010.5478885","DOIUrl":"https://doi.org/10.1109/HIBIT.2010.5478885","url":null,"abstract":"The abuse, overuse and misuse of beta-lactam antibiotics in treating bacterial infections have caused bacteria to develop resistance against them. One common antibiotic resistance mechanism utilized by bacteria is the production of beta-lactamase enzymes that cleave the amide bond in beta-lactam ring rendering the antibiotic ineffective. One way to combat this problem is to use beta-lactamase inhibitors in combination with beta-lactam antibiotics. Beta-lactamase inhibitor protein (BLIP) is an effective inhibitor of class A beta-lactamases such as TEM-1 and SHV-1. In the current research, the binding of BLIP to TEM-1 and to SHV-1 beta lactamase was investigated using molecular dynamics simulations. The binding free energies of BLIP complex with TEM-1 and SHV-1 betalactamases were calculated using Molecular Mechanic Poisson Bolztmann Surface Area (MM-PBSA) methodology. It was found that BLIP has significant differences in binding affinities toward TEM-1 and SHV-1 beta-lactamases.","PeriodicalId":215457,"journal":{"name":"2010 5th International Symposium on Health Informatics and Bioinformatics","volume":"2020 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2010-04-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126839158","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 4
Behavioural intension analysis of Avicenna® Hospital Information System Avicenna®医院信息系统的行为强度分析
2010 5th International Symposium on Health Informatics and Bioinformatics Pub Date : 2010-04-20 DOI: 10.1109/HIBIT.2010.5478906
Atife Z Enkal, Sevgi Özkan
{"title":"Behavioural intension analysis of Avicenna® Hospital Information System","authors":"Atife Z Enkal, Sevgi Özkan","doi":"10.1109/HIBIT.2010.5478906","DOIUrl":"https://doi.org/10.1109/HIBIT.2010.5478906","url":null,"abstract":"\"Hospital Information Systems\" are designed for improving the health quality of people and for the management of all the hospital's medical and administrative information in order to enable health professionals to perform their jobs effectively and efficiency. However the main problem has been raising that is whether hospital personnel want to use these systems while performing their tasks. This study tests an extended model by adding some factors to the original model that is based on the literature: technology acceptance model (TAM), to analyze the health professionals' behavioral intention to use hospital information system Avicenna®. The research is tested on the users who are able to use \"Hospital Information System\" of Yüksek İhtisas Hospital is located in Ankara, Turkey. Data is collected from 52 subjects who are health professionals (doctors, nurses, technical staff etc.) in hospital. Also correlation, explanatory and confirmation factor analysis was performed to test the reliability and validity of the questionnaire method. The structural equation modeling (SEM) technique has also been used to evaluate the models.","PeriodicalId":215457,"journal":{"name":"2010 5th International Symposium on Health Informatics and Bioinformatics","volume":"20 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2010-04-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126932078","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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