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Scandinavian journal of respiratory diseases. Supplementum最新文献

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Bronchial carcinoma. III. Quantitative measurements of the quality of survival. A prospective randomized study of the result of therapy in inoperable patients with localized disease. 支气管癌。3生存质量的定量测量。一项前瞻性随机研究对不能手术的局限性疾病患者的治疗结果。
Scandinavian journal of respiratory diseases. Supplementum Pub Date : 1979-01-01
E Nõu
{"title":"Bronchial carcinoma. III. Quantitative measurements of the quality of survival. A prospective randomized study of the result of therapy in inoperable patients with localized disease.","authors":"E Nõu","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Fifty-four bronchial carcinoma patients in clinico-anatomical stages 1-3 of the disease (localized disease) were randomly assigned to groups for radiotherapy, cyclophosphamide and placebo treatment, respectively. The results were assessed by the survival time and the quality of survival. The median survival time was 6.7 months for radiotherapy, 12.4 months for cyclophosphamide and 11.3 months for placebo. The median total sum of vitagram points was 44.5 for radiotherapy, 90.2 for cyclophosphamide and 81.8 for placebo. When calculated per month, the median sum of vitagram points was 6.2 for radiotherapy, 6.6 for cyclophosphamide and 7.0 for placebo. No significant differences were found between the treatment groups with respect to average survival time and and average vitagram point sums.</p>","PeriodicalId":21458,"journal":{"name":"Scandinavian journal of respiratory diseases. Supplementum","volume":"104 ","pages":"107-30"},"PeriodicalIF":0.0,"publicationDate":"1979-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"11592439","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Chromosome analysis of malignant human effusions in vivo. 人体内恶性积液的染色体分析。
Scandinavian journal of respiratory diseases. Supplementum Pub Date : 1979-01-01
R Korsgaard
{"title":"Chromosome analysis of malignant human effusions in vivo.","authors":"R Korsgaard","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":21458,"journal":{"name":"Scandinavian journal of respiratory diseases. Supplementum","volume":"105 ","pages":"1-100"},"PeriodicalIF":0.0,"publicationDate":"1979-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"11309593","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Fenoterol and post-exercise treatment of exercise-induced asthma [proceedings]. 非诺特罗和运动后治疗运动性哮喘[j]。
Scandinavian journal of respiratory diseases. Supplementum Pub Date : 1979-01-01
R C Borthwick
{"title":"Fenoterol and post-exercise treatment of exercise-induced asthma [proceedings].","authors":"R C Borthwick","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":21458,"journal":{"name":"Scandinavian journal of respiratory diseases. Supplementum","volume":"103 ","pages":"214"},"PeriodicalIF":0.0,"publicationDate":"1979-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"11499664","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The effects of ipratropium bromide on the histamine inhalation challenge in asthmatic and bronchitic patients. 异丙托溴铵对哮喘和支气管炎患者组胺吸入的影响。
Scandinavian journal of respiratory diseases. Supplementum Pub Date : 1979-01-01
L A Laitinen, A A Viljanen, B C Viljanen
{"title":"The effects of ipratropium bromide on the histamine inhalation challenge in asthmatic and bronchitic patients.","authors":"L A Laitinen,&nbsp;A A Viljanen,&nbsp;B C Viljanen","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":21458,"journal":{"name":"Scandinavian journal of respiratory diseases. Supplementum","volume":"103 ","pages":"215-8"},"PeriodicalIF":0.0,"publicationDate":"1979-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"11373782","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Pharmacology and toxicology of Atrovent. Atrovent的药理学和毒理学研究。
Scandinavian journal of respiratory diseases. Supplementum Pub Date : 1979-01-01
A Engelhardt
{"title":"Pharmacology and toxicology of Atrovent.","authors":"A Engelhardt","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The anticholinergic drug ipratropium bromide (Atrovent) can be described as having pharmacologically a high degree of activity and a certain bronchoselectivity when administered intravenously. Inhalation studies, however, indicate that this is the most suitable route of administration. Inhalation provides with small doses the most effective concentration locally at the smooth muscle of the airways without producing anticholinergic side effects due to absorption from the airways or from the gastrointestinal tract. In certain experimental models of allergic asthma, ipratropium bromide was shown to be capable of influencing favourably bronchoconstriction and mediator release. Extensive toxicological examinations revealed with high doses all typical symptoms of overdosing an anticholinergic drug, like mydriasis, dryness of the mucosae and meteorism with coprostasis. Acute and long term inhalation studies gave no evidence for a functional and morphological impairment of the lungs and airways.</p>","PeriodicalId":21458,"journal":{"name":"Scandinavian journal of respiratory diseases. Supplementum","volume":"103 ","pages":"110-5"},"PeriodicalIF":0.0,"publicationDate":"1979-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"11373907","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A double blind cross-over study of maximal expiratory flows and arterial blood gas tensions in normals, asthmatics and bronchitics after salbutamol and ipratropin. 沙丁胺醇和异丙托品对正常人、哮喘患者和支气管炎患者最大呼气流量和动脉血气张力的双盲交叉研究。
Scandinavian journal of respiratory diseases. Supplementum Pub Date : 1979-01-01
B Thiessen, O F Pedersen
{"title":"A double blind cross-over study of maximal expiratory flows and arterial blood gas tensions in normals, asthmatics and bronchitics after salbutamol and ipratropin.","authors":"B Thiessen,&nbsp;O F Pedersen","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>8 normals, 8 asthmatics and 8 bronchitics inhaled comparable doses of ipratropin and salbutamol. Five different flow-volume parameters were measured before and at intervals from 3 to 360 minutes after inhalation, on a total number of 2880 maximal effort expiratory flow-volume curves. Arterial blood gas tensions were measured before and 60 minutes after inhalation. In all parameters a significant larger effect (p less than 0.05) of ipratropin was found in normals, but in different time intervals. The parameter FEV1 and MEF at 50% of FVC showed the largest effect of salbutamol during the interval from 3 to 60 minutes in the asthma patients. None of the parameters showed significant difference in drug effects in the bronchitis patients. The findings suggested a more peripheral action of ipratropin than of salbutamol in the normals. No significant change in gas tensions were found after inhalation in any of the three groups.</p>","PeriodicalId":21458,"journal":{"name":"Scandinavian journal of respiratory diseases. Supplementum","volume":"103 ","pages":"170-7"},"PeriodicalIF":0.0,"publicationDate":"1979-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"11373916","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Mucociliary clearance in anti-asthmatic drug evaluation. 抗哮喘药物的纤毛粘膜清除率评价。
Scandinavian journal of respiratory diseases. Supplementum Pub Date : 1979-01-01
B Mossberg
{"title":"Mucociliary clearance in anti-asthmatic drug evaluation.","authors":"B Mossberg","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":21458,"journal":{"name":"Scandinavian journal of respiratory diseases. Supplementum","volume":"103 ","pages":"96-101"},"PeriodicalIF":0.0,"publicationDate":"1979-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"11499669","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The efficacy of terbutaline and fenoterol aerosols on adult exercise-induced asthma [proceedings]. 特布他林和非诺特罗气雾剂治疗成人运动性哮喘的疗效[论文集]。
Scandinavian journal of respiratory diseases. Supplementum Pub Date : 1979-01-01
R Tammivaara
{"title":"The efficacy of terbutaline and fenoterol aerosols on adult exercise-induced asthma [proceedings].","authors":"R Tammivaara","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":21458,"journal":{"name":"Scandinavian journal of respiratory diseases. Supplementum","volume":"103 ","pages":"212-3"},"PeriodicalIF":0.0,"publicationDate":"1979-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"11582382","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Smooth muscle constriction and mechanisms of gas trapping. 平滑肌收缩和气体捕获机制。
Scandinavian journal of respiratory diseases. Supplementum Pub Date : 1979-01-01
R Amyot, R Sergysels, L Delaunois, R Boileau, P T Macklem, R R Martin
{"title":"Smooth muscle constriction and mechanisms of gas trapping.","authors":"R Amyot,&nbsp;R Sergysels,&nbsp;L Delaunois,&nbsp;R Boileau,&nbsp;P T Macklem,&nbsp;R R Martin","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":21458,"journal":{"name":"Scandinavian journal of respiratory diseases. Supplementum","volume":"103 ","pages":"19-24"},"PeriodicalIF":0.0,"publicationDate":"1979-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"11499663","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Inhalative provocation test. When is it positive? 吸入激发试验。什么时候是正的?
Scandinavian journal of respiratory diseases. Supplementum Pub Date : 1979-01-01
H Matthys
{"title":"Inhalative provocation test. When is it positive?","authors":"H Matthys","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>A range for the airway resistance (R), reference resistance (Rref), quotient (R/Rref) measured by whole body plethysmography is given for unspecific inhalative provocation in asthmatic patients. 1. In patients with an initial R/Rref value less than 2 (R about 0,6 kPa/l/s) the non allergic reaction did not exceed an R/Rref quotient of 2,7. 2. Those patients with an initial R/Rref quotient greater than 2 but less than 5 reached an R/Rref value of 8.5 after non allergic provocation, which equals an R of about 1,75 kPa/l/s. It is recommended to provoke only those patients in whom the initial R/Rref quotient is in the beginning smaller than 2; because it is otherwise difficult to separate allergic from non allergic reactions and the necessary allergen induced bronchospasm might be harmful. Reference values for specific airway resistance have the advantage that we do not need a panting manouvre against a closed shutter which is often difficult to achieve especially with children during an asthmatic attack.</p>","PeriodicalId":21458,"journal":{"name":"Scandinavian journal of respiratory diseases. Supplementum","volume":"103 ","pages":"208-11"},"PeriodicalIF":0.0,"publicationDate":"1979-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"11512595","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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