Saudi Journal of Medical and Pharmaceutical Sciences最新文献

筛选
英文 中文
Bevacizumab with Paclitaxel and Carboplatin as Neo Adjuvant Chemotherapy for Stage 4 Ovarian Cancer- Case Report 贝伐单抗联合紫杉醇和卡铂作为第 4 期卵巢癌的新辅助化疗--病例报告
Saudi Journal of Medical and Pharmaceutical Sciences Pub Date : 2024-02-16 DOI: 10.36348/sjmps.2024.v10i02.009
Celia Thomas, Abdul Malik
{"title":"Bevacizumab with Paclitaxel and Carboplatin as Neo Adjuvant Chemotherapy for Stage 4 Ovarian Cancer- Case Report","authors":"Celia Thomas, Abdul Malik","doi":"10.36348/sjmps.2024.v10i02.009","DOIUrl":"https://doi.org/10.36348/sjmps.2024.v10i02.009","url":null,"abstract":"Ovarian cancer, the fifth most common neoplasia in women, presents challenges in diagnosis and treatment, often resulting in poor prognosis due to advanced stage at diagnosis and limited treatment options. Platinum-based chemotherapy and surgery have been the mainstay treatments, but efforts to improve outcomes with additional cytotoxic drugs have yielded mixed results. Angiogenesis plays a crucial role in tumor growth and metastasis, leading to the investigation of bevacizumab, a monoclonal antibody targeting vascular endothelial growth factor (VEGF). Clinical trials have demonstrated its efficacy in delaying disease progression in ovarian cancer. This case report illustrates the successful use of neoadjuvant chemotherapy followed by surgery and maintenance therapy with bevacizumab and olaparib in a patient with advanced ovarian cancer, highlighting the potential benefits of this treatment approach in improving survival outcomes.","PeriodicalId":21367,"journal":{"name":"Saudi Journal of Medical and Pharmaceutical Sciences","volume":"84 10","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140454686","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Updates in Oral Management of Dehydration and Electrolyte Disturbance in Infants and Children: A Systematic Review 婴幼儿脱水和电解质紊乱口服治疗的最新进展:系统回顾
Saudi Journal of Medical and Pharmaceutical Sciences Pub Date : 2024-02-12 DOI: 10.36348/sjmps.2024.v10i02.008
Sarah Emad Alsayed
{"title":"Updates in Oral Management of Dehydration and Electrolyte Disturbance in Infants and Children: A Systematic Review","authors":"Sarah Emad Alsayed","doi":"10.36348/sjmps.2024.v10i02.008","DOIUrl":"https://doi.org/10.36348/sjmps.2024.v10i02.008","url":null,"abstract":"Background: The ability of the first responder to identify and effectively treat hypovolemic shock will determine whether or not a child with severe volume depletion survives in the emergency room. Although the fundamentals of fluid and electrolyte therapy have been studied for decades, the issue is still difficult to resolve because there is no universally accepted therapeutic care approach. Objectives: This systematic review aims to study the updated management of dehydration and electrolyte disturbance in children and infants. Methods: PubMed, Science Direct, and Google Scholar were systematically searched for relevant literature. Rayyan QRCI was employed throughout this comprehensive process. Results & interpretation: This review included a total of ten studies with 2285 patients, and 883 (38.6%) were males. According to this comprehensive study, home-based therapy and ORS were successful in straightforward instances. Other methods, such as ORS plus Xyloglucan and ORS with honeybee added, were secure and efficient in reducing the frequency of vomiting and diarrhea. The electrolyte balance and rehydration of the patients were improved by diluted apple juice, rehydration treatments, and preferred fluids. However, gelatin tannate proved ineffective for rehydrating the child, although it advised against ever stopping breastfeeding. Drugs like intravenous Metoclopramide and Domperidone demonstrated efficacy for treating pediatric dehydration in the event that ORS failed.","PeriodicalId":21367,"journal":{"name":"Saudi Journal of Medical and Pharmaceutical Sciences","volume":"175 ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139843244","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Updates in Oral Management of Dehydration and Electrolyte Disturbance in Infants and Children: A Systematic Review 婴幼儿脱水和电解质紊乱口服治疗的最新进展:系统回顾
Saudi Journal of Medical and Pharmaceutical Sciences Pub Date : 2024-02-12 DOI: 10.36348/sjmps.2024.v10i02.008
Sarah Emad Alsayed
{"title":"Updates in Oral Management of Dehydration and Electrolyte Disturbance in Infants and Children: A Systematic Review","authors":"Sarah Emad Alsayed","doi":"10.36348/sjmps.2024.v10i02.008","DOIUrl":"https://doi.org/10.36348/sjmps.2024.v10i02.008","url":null,"abstract":"Background: The ability of the first responder to identify and effectively treat hypovolemic shock will determine whether or not a child with severe volume depletion survives in the emergency room. Although the fundamentals of fluid and electrolyte therapy have been studied for decades, the issue is still difficult to resolve because there is no universally accepted therapeutic care approach. Objectives: This systematic review aims to study the updated management of dehydration and electrolyte disturbance in children and infants. Methods: PubMed, Science Direct, and Google Scholar were systematically searched for relevant literature. Rayyan QRCI was employed throughout this comprehensive process. Results & interpretation: This review included a total of ten studies with 2285 patients, and 883 (38.6%) were males. According to this comprehensive study, home-based therapy and ORS were successful in straightforward instances. Other methods, such as ORS plus Xyloglucan and ORS with honeybee added, were secure and efficient in reducing the frequency of vomiting and diarrhea. The electrolyte balance and rehydration of the patients were improved by diluted apple juice, rehydration treatments, and preferred fluids. However, gelatin tannate proved ineffective for rehydrating the child, although it advised against ever stopping breastfeeding. Drugs like intravenous Metoclopramide and Domperidone demonstrated efficacy for treating pediatric dehydration in the event that ORS failed.","PeriodicalId":21367,"journal":{"name":"Saudi Journal of Medical and Pharmaceutical Sciences","volume":"18 13","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139783502","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Child Liver Abcess: Study of 12 Cases in the Pediatric Ward of the District Hospital of Bamako 儿童肝脓肿:对巴马科地区医院儿科病房 12 个病例的研究
Saudi Journal of Medical and Pharmaceutical Sciences Pub Date : 2024-02-06 DOI: 10.36348/sjmps.2024.v10i02.007
K. M, Sylla, F, Beydari, B. H, K. I, T. M, T. Y., Sacko, D, H. M, Bamba, K, S. D, Fané, B, Maïga, L, Kontao, N, Doumbia, A, Fatim, D, Maïga, M, Coulibaly, C, S. K, Sylla, M
{"title":"Child Liver Abcess: Study of 12 Cases in the Pediatric Ward of the District Hospital of Bamako","authors":"K. M, Sylla, F, Beydari, B. H, K. I, T. M, T. Y., Sacko, D, H. M, Bamba, K, S. D, Fané, B, Maïga, L, Kontao, N, Doumbia, A, Fatim, D, Maïga, M, Coulibaly, C, S. K, Sylla, M","doi":"10.36348/sjmps.2024.v10i02.007","DOIUrl":"https://doi.org/10.36348/sjmps.2024.v10i02.007","url":null,"abstract":"Hepatic abscess is a suppurative collection developed in a neoformed hepatic cavity as a result of the invasion and multiplication of micro-organisms. The prognosis depends on early diagnosis and rapid treatment. The aim of the study was to determine the clinical, biological, ultrasound and therapeutic characteristics of liver abscesses in children aged between 1 month and 15 years hospitalised in the Paediatrics Ward of the District Hospital in Commune V, Bamako. This was a retrospective descriptive study which took place from January 2017 to December 2020, i.e. a period of 4 years, and a prospective study from January 2019 to December 2020, including all children aged between 1 and 15 years in whom the diagnosis of liver abscess had been confirmed by liver ultrasound. Out of 2756 children hospitalised during the study period from January 2017 to December 2020, i.e. a période of 4 years, 12 patients were diagnosed with liver abscess, i.e. a frequency of 0.43% or 4 cases/1000 admissions, with a female predominance of 58.3%, i.e. a sex ratio of 0.7. The mean age was 57 ± 34 months, with extremes of 16 and 120 months. The main reason for consultation was abdominal pain associated with fever, accounting for 75% of patients. Pus culture was positive for Staphylococcus Aureus in one patient (8%). Amebic serology was positive in 33% of patients. Ultrasound revealed a predominance of single abscesses located in the right lobe of the liver in 42% of patients. However, 92% of patients were cured, with an average hospital stay of 12 days, ranging from 2 to 19 days. Liver abscesses uncommon in our context, an early diagnosis and management can improve the prognosis.","PeriodicalId":21367,"journal":{"name":"Saudi Journal of Medical and Pharmaceutical Sciences","volume":"254 3","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139858350","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Child Liver Abcess: Study of 12 Cases in the Pediatric Ward of the District Hospital of Bamako 儿童肝脓肿:对巴马科地区医院儿科病房 12 个病例的研究
Saudi Journal of Medical and Pharmaceutical Sciences Pub Date : 2024-02-06 DOI: 10.36348/sjmps.2024.v10i02.007
K. M, Sylla, F, Beydari, B. H, K. I, T. M, T. Y., Sacko, D, H. M, Bamba, K, S. D, Fané, B, Maïga, L, Kontao, N, Doumbia, A, Fatim, D, Maïga, M, Coulibaly, C, S. K, Sylla, M
{"title":"Child Liver Abcess: Study of 12 Cases in the Pediatric Ward of the District Hospital of Bamako","authors":"K. M, Sylla, F, Beydari, B. H, K. I, T. M, T. Y., Sacko, D, H. M, Bamba, K, S. D, Fané, B, Maïga, L, Kontao, N, Doumbia, A, Fatim, D, Maïga, M, Coulibaly, C, S. K, Sylla, M","doi":"10.36348/sjmps.2024.v10i02.007","DOIUrl":"https://doi.org/10.36348/sjmps.2024.v10i02.007","url":null,"abstract":"Hepatic abscess is a suppurative collection developed in a neoformed hepatic cavity as a result of the invasion and multiplication of micro-organisms. The prognosis depends on early diagnosis and rapid treatment. The aim of the study was to determine the clinical, biological, ultrasound and therapeutic characteristics of liver abscesses in children aged between 1 month and 15 years hospitalised in the Paediatrics Ward of the District Hospital in Commune V, Bamako. This was a retrospective descriptive study which took place from January 2017 to December 2020, i.e. a period of 4 years, and a prospective study from January 2019 to December 2020, including all children aged between 1 and 15 years in whom the diagnosis of liver abscess had been confirmed by liver ultrasound. Out of 2756 children hospitalised during the study period from January 2017 to December 2020, i.e. a période of 4 years, 12 patients were diagnosed with liver abscess, i.e. a frequency of 0.43% or 4 cases/1000 admissions, with a female predominance of 58.3%, i.e. a sex ratio of 0.7. The mean age was 57 ± 34 months, with extremes of 16 and 120 months. The main reason for consultation was abdominal pain associated with fever, accounting for 75% of patients. Pus culture was positive for Staphylococcus Aureus in one patient (8%). Amebic serology was positive in 33% of patients. Ultrasound revealed a predominance of single abscesses located in the right lobe of the liver in 42% of patients. However, 92% of patients were cured, with an average hospital stay of 12 days, ranging from 2 to 19 days. Liver abscesses uncommon in our context, an early diagnosis and management can improve the prognosis.","PeriodicalId":21367,"journal":{"name":"Saudi Journal of Medical and Pharmaceutical Sciences","volume":"6 11","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139798690","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Post Appendicectomy Fistula: A Review of Its Management in 50 Cases 阑尾切除术后瘘管:50 例治疗回顾
Saudi Journal of Medical and Pharmaceutical Sciences Pub Date : 2024-02-01 DOI: 10.36348/sjmps.2024.v10i02.004
Kazi Sohel Iqbal, Riditta Mustika, Sourov Hossain, Ruksana Parveen, Md. Alfazzaman Md. Alfazzaman, Md. Jamaluddin Md. Jamaluddin, Tanvir Ahmed Shohan, A. M. K. Hasan
{"title":"Post Appendicectomy Fistula: A Review of Its Management in 50 Cases","authors":"Kazi Sohel Iqbal, Riditta Mustika, Sourov Hossain, Ruksana Parveen, Md. Alfazzaman Md. Alfazzaman, Md. Jamaluddin Md. Jamaluddin, Tanvir Ahmed Shohan, A. M. K. Hasan","doi":"10.36348/sjmps.2024.v10i02.004","DOIUrl":"https://doi.org/10.36348/sjmps.2024.v10i02.004","url":null,"abstract":"Introduction: Open appendectomy (OA) and laparoscopic appendectomy (LA) are the choices of treatment for acute appendicitis. However, laparoscopic approach is emerging for the benefits it provides, but it also sometimes may has some drawbacks like OA including fistula. Objective: This retrospective study aims to investigate the management of fistula in 50 post appendicectomy fistula patients. Methods: A retrospective study was done at MH Samorita Medical College & Hospital, Hi-Tech Surgicare Hospital & Piles Centre, Savar Specialized Hospital and Lab Zone Hospital Savar, Bangladesh during January 2019 to December 2023 from January 2019 to December 2023, among the patients who had underwent laparoscopic appendicectomy and open appendicectomy. The total study population was 50, among which 33 (66%) patients were in open appendectomy and 17 (34%) were in laparoscopic appendectomy. The patients’ age group included 10 years to 50 years of both male and female patients. P< 0.005 was considered significant in this study. Results: Out of total study population, 33 were from OA (66%) and 17 were from LA (34%) group. Most of the study patients were male, aged 21-30 years age group. Fistulogram found to be the commonly use method to diagnose fistula. Tuberculosis was found to be the frequent cause of post appendicectomy fistula. Conclusion: Post appendicectomy seems to have different outcomes with some adverse impact, fistula is one of them. The present study finds that the chances of post appendicectomy fistula is less in LA group compared to OA. Proper study and better investigation may bring this to null with time.","PeriodicalId":21367,"journal":{"name":"Saudi Journal of Medical and Pharmaceutical Sciences","volume":"17 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139889616","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Atypical Presentation of a Pilocytic Astrocytoma at the Regional Hospital of Ségou in Mali country 马里塞古地区医院出现的非典型嗜酸性星形细胞瘤
Saudi Journal of Medical and Pharmaceutical Sciences Pub Date : 2024-02-01 DOI: 10.36348/sjmps.2024.v10i02.001
S. A, Coulibaly, O. S, Beydari, B. H, K. A, D. M, T. B, T. H, Kané, M, K. M, Diallo, O, Dama, M, C. O, Touré, A, Mounkoro, M, Kanikomo, D
{"title":"Atypical Presentation of a Pilocytic Astrocytoma at the Regional Hospital of Ségou in Mali country","authors":"S. A, Coulibaly, O. S, Beydari, B. H, K. A, D. M, T. B, T. H, Kané, M, K. M, Diallo, O, Dama, M, C. O, Touré, A, Mounkoro, M, Kanikomo, D","doi":"10.36348/sjmps.2024.v10i02.001","DOIUrl":"https://doi.org/10.36348/sjmps.2024.v10i02.001","url":null,"abstract":"Introduction: Pilocytic astrocytoma is the most common cerebral glioma in pediatric age, preferentially located in the posterior cerebral fossa. Atypical presentations have rarely been described in the literature. Clinical Case: We report a case of pilocytic astrocytoma whose appearance on CT scan is unusual. It concerns a young boy of 9 years old, who presented convulsive seizures since the age of 6 years old, followed by general practitioners with irregular treatment based on gardenal. 2 months ago the seizures became more frequent and this prompted a specialist consultation with the neurologist, after a brain scan he referred the patient to us. The neurological examination was unremarkable today. Brain CT with contrast showed a right parietal lesion. It was a lesion with a double cystic and fleshy component associated with calcifications with heterogeneous enhancement which amputated the posterior horn of the lateral ventricle. The radiological appearance was in favor of a low-grade oligodendroglioma. The patient underwent surgery with complete macroscopic excision of the lesion. Histological examination revealed a pilocytic astrocytoma (grade I). Conclusion: The usual radiological appearance of pilocytic astrocytoma combines a cystic part and a highly contrasting mural nodule. It rarely presents in the form of a supratentorial lesion with calcifications. This form of presentation is rare and can lead to confusion with other gliomas. We can achieve healing for the patient with total excision.","PeriodicalId":21367,"journal":{"name":"Saudi Journal of Medical and Pharmaceutical Sciences","volume":"175 ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139825282","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Post Appendicectomy Fistula: A Review of Its Management in 50 Cases 阑尾切除术后瘘管:50 例治疗回顾
Saudi Journal of Medical and Pharmaceutical Sciences Pub Date : 2024-02-01 DOI: 10.36348/sjmps.2024.v10i02.004
Kazi Sohel Iqbal, Riditta Mustika, Sourov Hossain, Ruksana Parveen, Md. Alfazzaman Md. Alfazzaman, Md. Jamaluddin Md. Jamaluddin, Tanvir Ahmed Shohan, A. M. K. Hasan
{"title":"Post Appendicectomy Fistula: A Review of Its Management in 50 Cases","authors":"Kazi Sohel Iqbal, Riditta Mustika, Sourov Hossain, Ruksana Parveen, Md. Alfazzaman Md. Alfazzaman, Md. Jamaluddin Md. Jamaluddin, Tanvir Ahmed Shohan, A. M. K. Hasan","doi":"10.36348/sjmps.2024.v10i02.004","DOIUrl":"https://doi.org/10.36348/sjmps.2024.v10i02.004","url":null,"abstract":"Introduction: Open appendectomy (OA) and laparoscopic appendectomy (LA) are the choices of treatment for acute appendicitis. However, laparoscopic approach is emerging for the benefits it provides, but it also sometimes may has some drawbacks like OA including fistula. Objective: This retrospective study aims to investigate the management of fistula in 50 post appendicectomy fistula patients. Methods: A retrospective study was done at MH Samorita Medical College & Hospital, Hi-Tech Surgicare Hospital & Piles Centre, Savar Specialized Hospital and Lab Zone Hospital Savar, Bangladesh during January 2019 to December 2023 from January 2019 to December 2023, among the patients who had underwent laparoscopic appendicectomy and open appendicectomy. The total study population was 50, among which 33 (66%) patients were in open appendectomy and 17 (34%) were in laparoscopic appendectomy. The patients’ age group included 10 years to 50 years of both male and female patients. P< 0.005 was considered significant in this study. Results: Out of total study population, 33 were from OA (66%) and 17 were from LA (34%) group. Most of the study patients were male, aged 21-30 years age group. Fistulogram found to be the commonly use method to diagnose fistula. Tuberculosis was found to be the frequent cause of post appendicectomy fistula. Conclusion: Post appendicectomy seems to have different outcomes with some adverse impact, fistula is one of them. The present study finds that the chances of post appendicectomy fistula is less in LA group compared to OA. Proper study and better investigation may bring this to null with time.","PeriodicalId":21367,"journal":{"name":"Saudi Journal of Medical and Pharmaceutical Sciences","volume":"58 ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139829604","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Apoplexy of Microprolactinoma after Cabergoline Therapy: Rare Situation but Big Emergency 卡麦角林治疗后的微泌乳素瘤中风:情况罕见但十分紧急
Saudi Journal of Medical and Pharmaceutical Sciences Pub Date : 2024-02-01 DOI: 10.36348/sjmps.2024.v10i02.003
Hamza El Jadi, Zakaria Toufga, Imane Moustaghit
{"title":"Apoplexy of Microprolactinoma after Cabergoline Therapy: Rare Situation but Big Emergency","authors":"Hamza El Jadi, Zakaria Toufga, Imane Moustaghit","doi":"10.36348/sjmps.2024.v10i02.003","DOIUrl":"https://doi.org/10.36348/sjmps.2024.v10i02.003","url":null,"abstract":"Pituitary apoplexy (PA) is a rare clinical situation caused by pituitary infarction with or without haemorrhage. Although it is usually spontaneous, dopaminergic agonists (DA) are known to be predisposing factors, particularly Bromocriptine, more rarely Cabergoline. We report the case of a 31-years-old patient with a microprolactinoma who developed acute visual acuity loss due to pituitary apoplexy 5 months after taking Cabergoline. The evolution was marked by a considerable improvement of the visual state. Pituitary apoplexy is a rare situation. Often reported with Bromocriptine, PA can also occur with Cabergoline. Due to the high mortality and morbidity of apoplexy, it should be borne in mind that close monitoring is necessary when treatment with DA is prescribed and the patient should be informed of this risk. Although DA precipitate risk, treatment can be continued for hormonal and anti-tumour remission.","PeriodicalId":21367,"journal":{"name":"Saudi Journal of Medical and Pharmaceutical Sciences","volume":"354 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139830873","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Atypical Presentation of a Pilocytic Astrocytoma at the Regional Hospital of Ségou in Mali country 马里塞古地区医院出现的非典型嗜酸性星形细胞瘤
Saudi Journal of Medical and Pharmaceutical Sciences Pub Date : 2024-02-01 DOI: 10.36348/sjmps.2024.v10i02.001
S. A, Coulibaly, O. S, Beydari, B. H, K. A, D. M, T. B, T. H, Kané, M, K. M, Diallo, O, Dama, M, C. O, Touré, A, Mounkoro, M, Kanikomo, D
{"title":"Atypical Presentation of a Pilocytic Astrocytoma at the Regional Hospital of Ségou in Mali country","authors":"S. A, Coulibaly, O. S, Beydari, B. H, K. A, D. M, T. B, T. H, Kané, M, K. M, Diallo, O, Dama, M, C. O, Touré, A, Mounkoro, M, Kanikomo, D","doi":"10.36348/sjmps.2024.v10i02.001","DOIUrl":"https://doi.org/10.36348/sjmps.2024.v10i02.001","url":null,"abstract":"Introduction: Pilocytic astrocytoma is the most common cerebral glioma in pediatric age, preferentially located in the posterior cerebral fossa. Atypical presentations have rarely been described in the literature. Clinical Case: We report a case of pilocytic astrocytoma whose appearance on CT scan is unusual. It concerns a young boy of 9 years old, who presented convulsive seizures since the age of 6 years old, followed by general practitioners with irregular treatment based on gardenal. 2 months ago the seizures became more frequent and this prompted a specialist consultation with the neurologist, after a brain scan he referred the patient to us. The neurological examination was unremarkable today. Brain CT with contrast showed a right parietal lesion. It was a lesion with a double cystic and fleshy component associated with calcifications with heterogeneous enhancement which amputated the posterior horn of the lateral ventricle. The radiological appearance was in favor of a low-grade oligodendroglioma. The patient underwent surgery with complete macroscopic excision of the lesion. Histological examination revealed a pilocytic astrocytoma (grade I). Conclusion: The usual radiological appearance of pilocytic astrocytoma combines a cystic part and a highly contrasting mural nodule. It rarely presents in the form of a supratentorial lesion with calcifications. This form of presentation is rare and can lead to confusion with other gliomas. We can achieve healing for the patient with total excision.","PeriodicalId":21367,"journal":{"name":"Saudi Journal of Medical and Pharmaceutical Sciences","volume":"57 2","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139885215","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
0
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
相关产品
×
本文献相关产品
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术官方微信