Revista do Instituto de Medicina Tropical de São Paulo最新文献_第2页

First occurrence of feline sporotrichosis in a metropolitan area of Central-West Brazil 巴西中西部城市地区首次出现猫孢子丝虫病

Revista do Instituto de Medicina Tropical de São Paulo Pub Date : 2024-04-05 DOI: 10.1590/S1678-9946202466019

Mariana Almeida Ferreira, Allana de Paula Castilho, Gabrielle Silveira Vargas, Bruna Elisa Patini, André Luís Elias Moreira, JA Santos, Roseli Santos de Freitas Xavier, Gilda Maria Barbaro Del Negro, Carlos Pelleschi Taborda, Isabella Dib Gremião, Álvaro Ferreira Júnior

{"title":"First occurrence of feline sporotrichosis in a metropolitan area of Central-West Brazil","authors":"Mariana Almeida Ferreira, Allana de Paula Castilho, Gabrielle Silveira Vargas, Bruna Elisa Patini, André Luís Elias Moreira, JA Santos, Roseli Santos de Freitas Xavier, Gilda Maria Barbaro Del Negro, Carlos Pelleschi Taborda, Isabella Dib Gremião, Álvaro Ferreira Júnior","doi":"10.1590/S1678-9946202466019","DOIUrl":"https://doi.org/10.1590/S1678-9946202466019","url":null,"abstract":"ABSTRACT Sporotrichosis is a neglected mycosis that affects human and animal hosts, including domestic cats. In Brazil, its most frequently diagnosed etiological agent is Sporothrix brasiliensis. Zoonotic transmission of S. brasiliensis occurs via direct contact between an infected cat and a susceptible human host. Notification of confirmed cases of feline sporotrichosis is not mandatory in Brazil. The metropolitan area of Goiania city can be considered a silent area for the occurrence of feline sporotrichosis. In this context, voluntary reporting of feline sporotrichosis cases is recommended for all healthcare professionals. This study aimed to report the first occurrence of S. brasiliensis in a cat from the metropolitan area of Goiania city. Cytopathology, mycology, thermal dimorphism and calmodulin gene amplification tests were performed. The mycological and molecular biological diagnoses corresponded to S. brasiliensis. The etiological agent of zoonotic sporotrichosis was detected in the metropolitan area of Goiania city, and therefore there is a risk of the emergence of new cases of cats infected with S. brasiliensis and the occurrence of zoonotic transmission of this fungus.","PeriodicalId":21231,"journal":{"name":"Revista do Instituto de Medicina Tropical de São Paulo","volume":"14 S1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-04-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140737348","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Can COVID-19 impact the natural history of paracoccidioidomycosis? Insights from an atypical chronic form of the mycosis COVID-19会影响副球孢子菌病的自然史吗？非典型慢性真菌病的启示

Revista do Instituto de Medicina Tropical de São Paulo Pub Date : 2024-01-05 DOI: 10.1590/s1678-9946202466057err

引用次数: 0

Post-discharge all-cause mortality in COVID-19 recovered patients hospitalized in 2020: the impact of chronic kidney disease 2020年住院的COVID-19康复患者出院后的全因死亡率：慢性肾病的影响

Revista do Instituto de Medicina Tropical de São Paulo Pub Date : 2024-01-05 DOI: 10.1590/S1678-9946202466001

Guilherme Schittine Bezerra Lomba, Pedro Henrique Abreu da Silva, N. F. Rosário, Thalia Medeiros, L. Alves, Andrea Alice Silva, Jorge Reis Almeida, J. Lugon

{"title":"Post-discharge all-cause mortality in COVID-19 recovered patients hospitalized in 2020: the impact of chronic kidney disease","authors":"Guilherme Schittine Bezerra Lomba, Pedro Henrique Abreu da Silva, N. F. Rosário, Thalia Medeiros, L. Alves, Andrea Alice Silva, Jorge Reis Almeida, J. Lugon","doi":"10.1590/S1678-9946202466001","DOIUrl":"https://doi.org/10.1590/S1678-9946202466001","url":null,"abstract":"ABSTRACT In Brazil, the COVID-19 burden was substantial, and risk factors associated with higher in-hospital mortality rates have been extensively studied. However, information on short-term all-cause mortality and the factors associated with death in patients who survived the hospitalization period of acute SARS-CoV-2 infection is limited. We analyzed the six-month post-hospitalization mortality rate and possible risk factors of COVID-19 patients in a single center in Brazil. This is a retrospective cohort study focused on a six-month follow-up. The exclusion criteria were death during hospitalization, transference to another hospital, and age under 18. We collected data from the charts of all hospitalized patients from March 2020 to December 2020 with a positive RT-PCR test for SARS-CoV-2, resulting in a sample size of 106 patients. The main outcome was death after hospitalization, whereas comorbidities and demographics were evaluated as risk factors. The crude post-hospitalization death rate was 16%. The first 30 days of follow-up had the highest mortality rate. In a Cox regression model for post-hospitalization mortality, previous chronic kidney disease (HR, 4.06, 95%CI 1.46 – 11.30) and longer hospital stay (HR 1.01, 95%CI 1.00 – 1.02) were the only factors statistically associated with death. In conclusion, a high six-month all-cause mortality was observed. Within the six-month follow-up, a higher risk of death was observed for patients who had prior CKD and longer hospital stay. These findings highlight the importance of more intensive medical surveillance during this period.","PeriodicalId":21231,"journal":{"name":"Revista do Instituto de Medicina Tropical de São Paulo","volume":"2 12","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-01-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139380959","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Severe esophagitis induced by antituberculosis drugs: a case report 抗结核药物诱发的严重食管炎：一份病例报告

Revista do Instituto de Medicina Tropical de São Paulo Pub Date : 2024-01-05 DOI: 10.1590/S1678-9946202466002

Roxana Flores Mamani, Franciele Moreira Silva, Marcos Vidal de Lima-Júnior, Juliana Paitach de Oliveira Lima, Vitor Montez Vianna, Rivelino Trindade de Azevedo, B. McBenedict, E. Martins

引用次数: 0

The decline of measles antibody titers in previously vaccinated adults: a cross-sectional analysis 曾接种过疫苗的成年人麻疹抗体滴度的下降：横断面分析

Revista do Instituto de Medicina Tropical de São Paulo Pub Date : 2024-01-05 DOI: 10.1590/S1678-9946202466004

A. P. Castiñeiras, A. Sales, C. M. Picone, Constância Lima Diogo, Á. D. Rossi, R. Galliez, Orlando da Costa Ferreira Jr, T. M. Castineiras, Marta Heloísa Lopes, Ana Marli Christovam Sartori

{"title":"The decline of measles antibody titers in previously vaccinated adults: a cross-sectional analysis","authors":"A. P. Castiñeiras, A. Sales, C. M. Picone, Constância Lima Diogo, Á. D. Rossi, R. Galliez, Orlando da Costa Ferreira Jr, T. M. Castineiras, Marta Heloísa Lopes, Ana Marli Christovam Sartori","doi":"10.1590/S1678-9946202466004","DOIUrl":"https://doi.org/10.1590/S1678-9946202466004","url":null,"abstract":"ABSTRACT The global reemergence of measles in 2018–2019 reinforces the relevance of high-coverage immunization to maintain the disease elimination. During an outbreak in the Sao Paulo State in 2019, several measles cases were reported in individuals who were adequately vaccinated according to the current immunization schedule recommends. This study aimed to assess measles IgG antibody seropositivity and titers in previously vaccinated adults. A cross-sectional study was conducted at CRIE-HC-FMUSP (Sao Paulo, Brazil) in 2019. It included healthy adults who had received two or more Measles-Mumps-Rubella vaccines (MMR) and excluded individuals with immunocompromising conditions. Measles IgG antibodies were measured and compared by ELISA (Euroimmun®) and chemiluminescence (LIASON®). The association of seropositivity and titers with variables of interest (age, sex, profession, previous measles, number of measles-containing vaccine doses, interval between MMR doses, and time elapsed since the last MMR dose) was analyzed. A total of 162 participants were evaluated, predominantly young (median age 30 years), women (69.8%) and healthcare professionals (61.7%). The median interval between MMR doses was 13.2 years, and the median time since the last dose was 10.4 years. The seropositivity rate was 32.7% by ELISA and 75.3% by CLIA, and a strong positive correlation was found between the tests. Multivariate analyses revealed that age and time since the last dose were independently associated with positivity. Despite being a single-center evaluation, our results suggest that measles seropositivity may be lower than expected in adequately immunized adults. Seropositivity was higher among older individuals and those with a shorter time since the last MMR vaccine dose.","PeriodicalId":21231,"journal":{"name":"Revista do Instituto de Medicina Tropical de São Paulo","volume":"53 12","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-01-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139381793","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Evaluation of larval surface antigens from infective larvae of Strongyloides venezuelensis for the serodiagnosis of human strongyloidiasis 评估用于人类强直性脊柱炎血清诊断的委内瑞拉强直性脊柱炎感染性幼虫表面抗原

Revista do Instituto de Medicina Tropical de São Paulo Pub Date : 2024-01-05 DOI: 10.1590/S1678-9946202466001err

引用次数: 0