Alexandria Journal of Science and Technology最新文献

Geochronology and petrogenesis of the Cryogenian Sukari granite intrusion, Central Eastern Desert, Egypt: Inferences from whole rock geochemistry, zircon U-Pb-Hf isotopes and trace elements 埃及东部沙漠中部低碳苏卡里花岗岩侵入体的地质年代和岩石成因：全岩地球化学、锆石 U-Pb-Hf 同位素和微量元素推论

Alexandria Journal of Science and Technology Pub Date : 2024-07-06 DOI: 10.21608/ajst.2024.288041.1031

Aya Fawzy Harhash, Ahmed Ali Kamal El Deen, Khalil Ishaq Khalil, Abdel-Kader Mohamed Moghazi

引用次数: 0

In vitro and in silico antioxidant and antidiabetic properties of zinc oxide-chlorogenic acid nanoparticles composite 氧化锌-绿原酸复合纳米粒子的体外和硅学抗氧化和抗糖尿病特性

Alexandria Journal of Science and Technology Pub Date : 2024-02-08 DOI: 10.21608/ajst.2024.261549.1026

Aisha Albadawi, Amany Elkashef, Mohammed Nofel, Maysara El-Salakawy, Sofia Khalil, Shaymaa A. Abdulmalek, Doaa Ghareeb

引用次数: 0

In vitro and in silico antioxidant and antidiabetic properties of zinc oxide-chlorogenic acid nanoparticles composite 氧化锌-绿原酸复合纳米粒子的体外和硅学抗氧化和抗糖尿病特性

Alexandria Journal of Science and Technology Pub Date : 2024-02-08 DOI: 10.21608/ajst.2024.261549.1026

Aisha Albadawi, Amany Elkashef, Mohammed Nofel, Maysara El-Salakawy, Sofia Khalil, Shaymaa A. Abdulmalek, Doaa Ghareeb

引用次数: 0

Signature Verification Based on Deep Learning 基于深度学习的签名验证

Alexandria Journal of Science and Technology Pub Date : 2023-12-07 DOI: 10.21608/ajst.2023.236375.1016

Wessam Salama

{"title":"Signature Verification Based on Deep Learning","authors":"Wessam Salama","doi":"10.21608/ajst.2023.236375.1016","DOIUrl":"https://doi.org/10.21608/ajst.2023.236375.1016","url":null,"abstract":": Signature verification is considered one of the main features in determining the person identity. Our proposed framework emphasizes the potential of Deep Learning Models (DLMs) in revolutionizing signature verification techniques and underscores the need for continuous exploration and advancement in the realm of automated signature authentication. Therefore, five pre-trained DLMs, ResNet50, DenseNet121, MobileNetV3, InceptionV3, and VGG16, based on four different datasets, CEDAR, BH-Sig260 Bengali, BHSig260 Hindi, and ICDAR 2011(Dutch),are introduced in this paper to verify the person identity. Furthermore, data augmentation techniques are applied to overcome dataset limitations and increase the framework's performance. Additionally, transfer learning and fine-tuning techniques are performed to reduce computational time and memory usage. It is observed that the InceptionV3 DLM based on the ICDAR 2011 (Dutch) achieved the best performance of 100% accuracy, 100% AUC and 100% sensitivity. While, CEDAR Dataset achieves performance with an accuracy of 99.76%, an AUC of 99.94%, sensitivity of 99.76%, precision of 99.76%, an F1-score of 99.71%, score, and a computational time of 13.627s.","PeriodicalId":211963,"journal":{"name":"Alexandria Journal of Science and Technology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-12-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139011901","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Molecular mechanisms associated with ferroptosis during various pulmonary disorders and the possible therapeutic regimens for lung cancer. 各种肺部疾病中与铁下垂相关的分子机制以及肺癌可能的治疗方案。

Alexandria Journal of Science and Technology Pub Date : 2023-08-22 DOI: 10.21608/ajst.2023.215256.1011

Doaa Ghareeb, Maysara El-Salakawy

引用次数: 0

Conversion of bare corn cobs waste into sustainable and ecofriendly nanobiosorbent for effective removal of cationic basic fuchsin and methylene blue dyes from water 光秃秃的玉米芯废物转化为可持续和环保的纳米生物吸附剂，有效去除水中的阳离子碱性紫红和亚甲基蓝染料

Alexandria Journal of Science and Technology Pub Date : 2023-08-17 DOI: 10.21608/ajst.2023.216152.1013

M. Mahmoud, G. Nabil, Rana M. Tharwat, Amir M. Abdelfattah

引用次数: 0

Protein and Peptide-based Nanoparticles as an emerging strategy to tackle cancer drug resistance 基于蛋白质和肽的纳米颗粒作为解决癌症耐药的新兴策略

Alexandria Journal of Science and Technology Pub Date : 2023-08-10 DOI: 10.21608/ajst.2023.206740.1008

M. Abdellatif, Islam A Hassanin, Yosra H. Mahmoud, M. Teleb, A. Bekhit, Sherine N. Khattab

{"title":"Protein and Peptide-based Nanoparticles as an emerging strategy to tackle cancer drug resistance","authors":"M. Abdellatif, Islam A Hassanin, Yosra H. Mahmoud, M. Teleb, A. Bekhit, Sherine N. Khattab","doi":"10.21608/ajst.2023.206740.1008","DOIUrl":"https://doi.org/10.21608/ajst.2023.206740.1008","url":null,"abstract":": Cancer treatment has been confronted with serious challenges. These challenges stemmed from the heterogeneity of tumor microenvironment, as well as genetic and epigenetic factors related to cancer cells. The changes imposed by the tumor lead to the development of acquired resistance. Drug efflux, inhibition of apoptosis and immunosuppression are examples of resistance mechanisms imposed by cancer cells. Nanotechnology has sought to overcome these resistance mechanisms through enhanced cellular uptake, activation of alternative pathways by combined drug delivery, or targeting immune cells leading to their activation and proliferation. Several types of nanomedicine-based systems were implemented; however, protein and peptide nanoparticles remain one versatile tool in drug delivery, providing preferable physicochemical and biological implications. Notably, protein and peptide nanocarriers can also exhibit enhanced cellular uptake, the possibility of tuned drug release, and hence, better tumor targetability. Here, we present the methods of fabrication, physicochemical characteristics, biological mplications, and future perspectives, focusing on overcoming cancer drug resistance","PeriodicalId":211963,"journal":{"name":"Alexandria Journal of Science and Technology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-08-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116365292","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0