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Surface Measurement of the Human Lymphocyte Micro-Nucleus in Image Affected by Alterations 改变后人体淋巴细胞微核图像的表面测量
2007 IEEE International Workshop on Medical Measurement and Applications Pub Date : 2007-05-04 DOI: 10.1109/MEMEA.2007.4285171
D. Grimaldi, F. Lamonaca
{"title":"Surface Measurement of the Human Lymphocyte Micro-Nucleus in Image Affected by Alterations","authors":"D. Grimaldi, F. Lamonaca","doi":"10.1109/MEMEA.2007.4285171","DOIUrl":"https://doi.org/10.1109/MEMEA.2007.4285171","url":null,"abstract":"In order to relieve structural chromosome aberrations, a new architecture of flow cytometer measurement device able to recognize and automatic count the Micro Nucleuses (MNs) on the acquired images of human lymphocytes has been pointed out. The technique adopted to perform the MN detection is based on the pattern matching algorithm. Biologist experts recommend that the correct detection of MN must respect the condition that the MN's surface is in the range off [1/3, 1/16] of the nucleus. The pattern matching algorithm can give only a coarse evaluation of the MN dimension. On the basis of these considerations, the paper proposes to cascade the pattern matching algorithm and the blob analysis in order to achieve the accurate evaluation of the MN surface. In order to evaluate the valid gray level used to threshold the image the pattern matching algorithm furnishes: (i) the coordinate (x, y) and (ii) the parameter about the coarse evaluation of MN dimension. So the blob analysis can be applied and the surfaces of both the MN and the nucleuses are accurately evaluated.","PeriodicalId":211161,"journal":{"name":"2007 IEEE International Workshop on Medical Measurement and Applications","volume":"22 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2007-05-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115424253","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 9
Implementation of SPR-Biosensors for Express-Diagnostics of Acute Viral Infection and Mycotocsicosis spr -生物传感器在急性病毒感染和真菌病快速诊断中的应用
2007 IEEE International Workshop on Medical Measurement and Applications Pub Date : 2007-05-04 DOI: 10.1109/MEMEA.2007.4285150
M. Starodub, V. Romanov, R. Kochan, A. Sachenko, O. Kochan
{"title":"Implementation of SPR-Biosensors for Express-Diagnostics of Acute Viral Infection and Mycotocsicosis","authors":"M. Starodub, V. Romanov, R. Kochan, A. Sachenko, O. Kochan","doi":"10.1109/MEMEA.2007.4285150","DOIUrl":"https://doi.org/10.1109/MEMEA.2007.4285150","url":null,"abstract":"A structure of instrumentation for express-diagnostics of acute viral infection and mycotocsicosis is proposed. It includes an optoelectronic sensor based on surface plasmon resonance and uses artificial neural networks for sensor's signal processing. As result the reliability of diagnostics and resource of developed analytical instrumentation was increased. Using the sensor structures features for saving its parameters allowed to develop the viral-independent measurement transducer.","PeriodicalId":211161,"journal":{"name":"2007 IEEE International Workshop on Medical Measurement and Applications","volume":"116 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2007-05-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124136032","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 7
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