RespirationPub Date : 2025-06-13DOI: 10.1159/000546843
Sarah Bettina Stanzel, Jens Spiesshoefer, Franziska C Trudzinski, Christian G Cornelissen, Hans-Joachim Kabitz, Hans Fuchs, Matthias Boentert, Tim Mathes, Andrej Michalsen, Sven Hirschfeld, Michael Dreher, Wolfram Windisch, Stephan Walterspacher
{"title":"German National Guideline for Treating Chronic Respiratory Failure with Non-Invasive Ventilation.","authors":"Sarah Bettina Stanzel, Jens Spiesshoefer, Franziska C Trudzinski, Christian G Cornelissen, Hans-Joachim Kabitz, Hans Fuchs, Matthias Boentert, Tim Mathes, Andrej Michalsen, Sven Hirschfeld, Michael Dreher, Wolfram Windisch, Stephan Walterspacher","doi":"10.1159/000546843","DOIUrl":"https://doi.org/10.1159/000546843","url":null,"abstract":"<p><p>The german guideline on non-invasive ventilation offers comprehensive recommendations for the treatment of chronic respiratory failure in various underlying conditions, such as COPD, thoraco-restrictive diseases, obesity-hypoventilation syndrome, and neuromuscular diseases. The aim of the guideline is to improve the treatment of patients with chronic respiratory insufficiency using non-invasive ventilation and to make the indications and therapy recommendations accessible to all involved in the treatment process. It is based on the latest scientific evidence and replaces the previous guideline from 2017. This revised guideline provides detailed recommendations on the application of non-invasive ventilation, ventilation settings, and the subsequent follow-up of treatment. In addition to the updated evidence, important new features of this guideline include new recommendations on patient care and numerous detailed treatment pathways that make the guideline more user-friendly. Furthermore, a completely revised section is dedicated to ethical issues and offers recommendations for end-of-life care. This guideline is an important tool for physicians and other healthcare professionals to optimize the care of patients with chronic respiratory failure.</p>","PeriodicalId":21048,"journal":{"name":"Respiration","volume":" ","pages":"1-100"},"PeriodicalIF":3.5,"publicationDate":"2025-06-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144302762","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"r-EBUS sign and cryo-extraction of a pulmonary hydatid cyst.","authors":"Evangelia Koukaki, Nektarios Anagnostopoulos, Ilias C Papanikolaou, Agamemnon Bakakos, Stavroula Zaneli, Grigoris Stratakos","doi":"10.1159/000546841","DOIUrl":"https://doi.org/10.1159/000546841","url":null,"abstract":"<p><p>A 36-year-old female, never smoker, presented with 8-month history of persistent cough reporting no allergies, occupational or environmental exposures. Routine lab-tests were unremarkable. A non-contrast CT and PET-CT revealed an FDG avid (SUVmax 3.8), 3.5x2.8cm solid lesion adjacent to the major fissure of the right lung with no other findings reported (Fig.1). She was referred to our IP Unit after non-diagnostic bronchoscopy and CT-guided FNB. Following virtual segmentation and pathway analysis of the lesion, bronchoscopy with a 4.9mm outer diameter bronchoscope, revealed a whitish lesion obstructing a sub-sub-segmental orifice of RB8 (Fig.2). Forceps biopsies yielded acellular, non-diagnostic material by rapid-on-site-evaluation (ROSE). Radial endobronchial ultrasound (rEBUS) probe was inserted beneath the lesion to appreciate the presence of vessels prior to cryo-debulking. Interestingly, rEBUS revealed an unusual pattern of concentrical folds indicating walls of a ruptured cyst (Fig.3). Using a 1.1mm cryoprobe, the lesion was successfully removed at first attempt (5 sec freezing time) without complications apart from self-limited bleeding with no need for bronchial blocker(Fig.4). The extracted white membranes were consistent with hydatid cysts. Prophylactic corticosteroids and antihistamines were administered. Pulmonary echinococcosis was confirmed by pathology, positive serum Echinococcus IgG and presence of hooklets in bronchial washing. Patient was discharged on albendazole. Post-bronchoscopy x-ray and chest CT showed radiologic improvement (Fig.5,6). While hydatid cysts have been previously observed and removed bronchoscopically, this is the first report of rEBUS guided cryo-debulking [1,2]. rEBUS sign of concentric cystic walls may aid diagnosis, exclude presence of large vascular structures and ensure a safe cryo-extraction.</p>","PeriodicalId":21048,"journal":{"name":"Respiration","volume":" ","pages":"1-10"},"PeriodicalIF":3.5,"publicationDate":"2025-06-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144286349","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
RespirationPub Date : 2025-06-12DOI: 10.1159/000546873
Eveline C F Gerretsen, Herman E Popeijus, Jouke T Annema, Paul F Clementsen, Lorenzo Corbetta, Daniela Gompelmann, Erik H F M van der Heijden, Birgitta I Hiddinga, Walther N K A van Mook, Mohammed Munavvar, Frank W J M Smeenk, Marleen Groenier
{"title":"Development and validation of two bronchoscopy knowledge assessments.","authors":"Eveline C F Gerretsen, Herman E Popeijus, Jouke T Annema, Paul F Clementsen, Lorenzo Corbetta, Daniela Gompelmann, Erik H F M van der Heijden, Birgitta I Hiddinga, Walther N K A van Mook, Mohammed Munavvar, Frank W J M Smeenk, Marleen Groenier","doi":"10.1159/000546873","DOIUrl":"https://doi.org/10.1159/000546873","url":null,"abstract":"<p><strong>Introduction: </strong>Simulation-based training (SBT) is a key method for teaching bronchoscopy skills to pulmonology residents. A theoretical foundation can enhance SBT efficiency. This study developed and evaluated the validity of an anatomy and theoretical bronchoscopy exam using Kane's validity framework.</p><p><strong>Methods: </strong>19 anatomy and 58 theoretical exam questions, developed by pulmonology experts, were assessed through two Delphi rounds. Both exams were then taken by 53 prepared pulmonology residents. The theoretical exam was also taken by three unprepared groups: novices, intermediates and experts. Using the residents' data, scoring evidence for the theoretical exam was evaluated using item difficulty and item discrimination indices, and generalization evidence was assessed using Cronbach's alpha. Extrapolation evidence was obtained by comparing theoretical exam scores across the different groups. Implications evidence for both exams was gathered by evaluating residents' preparedness, based on exam performance and instructor feedback.</p><p><strong>Results: </strong>The Delphi procedure resulted in 19 anatomy and 31 theoretical questions. Item difficulty values predominantly ranged from 0.85-1.0, item discrimination indices mostly ranged from 0.0-0.25. Cronbach's alpha was 0.55. While scores appeared to correlate with experience, no significant differences were observed between the four groups. Most residents passed both exams on their first attempt, and instructors rated their anatomical knowledge as good.</p><p><strong>Conclusion: </strong>Expert involvement and acceptable item difficulty, item discrimination and internal consistency supported the exams' validity. The exams also effectively motivated residents to prepare for SBT. These findings highlight the value of pre-SBT exams in enhancing residents' preparation, allowing more time to focus on mastering procedural skills.</p>","PeriodicalId":21048,"journal":{"name":"Respiration","volume":" ","pages":"1-19"},"PeriodicalIF":3.5,"publicationDate":"2025-06-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144286348","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
RespirationPub Date : 2025-06-10DOI: 10.1159/000546827
Peizhu Su, Yueming Liang, Yongqi Liang, Qingsen Zhang, Huixin He, Lars Konge, Kristoffer Mazanti Cold, Jieming He, Weijun Huang
{"title":"Feedback from human instructors is superior to guidance by a virtual reality simulator when learning flexible bronchoscopy - a randomized controlled trial.","authors":"Peizhu Su, Yueming Liang, Yongqi Liang, Qingsen Zhang, Huixin He, Lars Konge, Kristoffer Mazanti Cold, Jieming He, Weijun Huang","doi":"10.1159/000546827","DOIUrl":"https://doi.org/10.1159/000546827","url":null,"abstract":"<p><p>[Background] Virtual reality (VR) simulators have been applied to bronchoscopy training, providing trainees with useful live feedback and guidance. Therefore, VR guidance could be superior to expert guidance in simulation-based. [Research Question] Does VR simulator guidance outperform guidance from expert instructors for novices navigating the bronchial tree? [Study Design and Methods] A randomized controlled trial was conducted with 36 residents using the EndoSim simulator. The trainees were divided into three groups: VR-guidance group, tutor-guidance group, and control group. They performed for 12 consecutive practice sessions, conducting a full, structured inspection of the bronchial tree, and were evaluated according to: Structured Progress (SP), Diagnostic Completeness (DC), procedure time (PT), and National Aeronautics and Space Administration Task Load Index (NASA-TLX index). [Results] All three groups showed an improvement in SP, DC, PT and NASA-TLX during their 12 procedures (P<.05), without a decrease in performance three weeks later (P>0.05). SP was the only distinguished metric among the three groups. Tutor guidance had a significantly better impact on the novices` SP compared to both VR-guidance (18±0 VS 15.0±5.3, P=.026) and the control group (18±0 VS 15.5±4.5, P=.017 ). Participants in the VR guidance group did not outperform the control group (P=1.00). [Interpretation] Tutor feedback is superior to VR guidance feedback and no feedback. uman supervisor guidance, enhances bronchoscopy quality, and structured progress offers a more nuanced assessment of bronchoscopic navigational skills than diagnostic completeness.</p>","PeriodicalId":21048,"journal":{"name":"Respiration","volume":" ","pages":"1-16"},"PeriodicalIF":3.5,"publicationDate":"2025-06-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144267206","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
RespirationPub Date : 2025-05-30DOI: 10.1159/000546433
Hayoung Seong, Soo Han Kim, Jeongha Mok, Mi-Hyun Kim, Min Ki Lee, Kyungbin Kim, Jung Seop Eom
{"title":"Cryobiopsy-Based Tri-Modality Sampling Using an Ultrathin Bronchoscope for the Diagnosis of Peripheral Lung Lesions: A Prospective Observational Study.","authors":"Hayoung Seong, Soo Han Kim, Jeongha Mok, Mi-Hyun Kim, Min Ki Lee, Kyungbin Kim, Jung Seop Eom","doi":"10.1159/000546433","DOIUrl":"10.1159/000546433","url":null,"abstract":"<p><strong>Introduction: </strong>Transbronchial lung biopsy using radial probe endobronchial ultrasound (RP-EBUS) is an important modality for diagnosing peripheral lung lesions (PLLs), but unmet needs remain. This study evaluates the diagnostic yields and safety of cryobiopsy-based tri-modality sampling using an ultrathin bronchoscope (UTB) with RP-EBUS for diagnosing PLLs.</p><p><strong>Methods: </strong>This prospective observational pilot study was conducted from November 2023 to January 2024, and included patients with PLLs ≤30 mm in diameter. Bronchoscopic procedures were performed using a UTB guided by RP-EBUS. Tri-modality sampling was sequentially conducted using cryobiopsy, forceps biopsy, and transbronchial needle aspiration (TBNA). The primary outcome was cumulative diagnostic yield, and secondary outcomes included the diagnostic yield of each modality and adverse events.</p><p><strong>Results: </strong>Fifty patients with PLLs, with a median diameter of 20.3 mm, were included. A bronchus sign was present in 66% of cases, and lesions were invisible on RP-EBUS in three instances. The overall cumulative diagnostic yield was 78%. The diagnostic yields were 78.7%, 66.7%, and 54.2% for cryobiopsy, forceps biopsy, and TBNA, respectively. Adding forceps biopsy to cryobiopsy improved the diagnostic yield by 4%, from 74% to 78%, and increased sensitivity for malignancy by 5.1%, from 84.6% to 89.7%. TBNA did not provide any additional improvement in diagnostic yield or sensitivity to malignancy. Bleeding occurred in 68% of the patients, with 28% experiencing grade 3 bleeding, all managed without life-threatening complications.</p><p><strong>Conclusion: </strong>Cryobiopsy-based combination sampling modality using UTB is feasible and safe for diagnosing PLLs, offering high diagnostic yield and improved sensitivity for malignancy.</p>","PeriodicalId":21048,"journal":{"name":"Respiration","volume":" ","pages":"1-12"},"PeriodicalIF":3.5,"publicationDate":"2025-05-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12176350/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144199947","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
RespirationPub Date : 2025-05-28DOI: 10.1159/000546341
Richard Westley, Avinash Aujayeb, Rahul Bhatnagar, Duneesha De Fonseka
{"title":"Local anaesthetic thoracoscopy practice in the United Kingdom in 2024 - a snapshot survey.","authors":"Richard Westley, Avinash Aujayeb, Rahul Bhatnagar, Duneesha De Fonseka","doi":"10.1159/000546341","DOIUrl":"https://doi.org/10.1159/000546341","url":null,"abstract":"<p><strong>Introduction: </strong>Local anaesthetic thoracoscopy (LAT) is widely available in the United Kingdom (UK). It is often the investigation of choice for unexplained exudative pleural effusions. There are no agreed national standards regarding LAT, with many sites following locally developed guidelines. The last survey of UK practice was in 2017.</p><p><strong>Methods: </strong>An electronic survey was circulated to UK Pleural Society (UKPS) members and through direct communication with centres known to be undertaking LAT. Invited centres were requested to distribute the survey further.</p><p><strong>Results: </strong>37 responses were included. LAT remains the preferred investigation for an undiagnosed exudative pleural effusion (32/37, 87%). The number of trained thoracoscopists ranged from 1 to 6. Thirty centres (81%) had dedicated thoracoscopy lists with varying frequency. Nineteen (51%) centres routinely admitted patients post thoracoscopy (compared to 76% in 2017). Thirty centres (81%) did not routinely administer antibiotics. Thirty-five centres (95%) routinely used sedation, the commonest agent being midazolam, typically in combination with an opiate. Eleven centres (30%) utilised other pre-medications, whilst 8/37 (22%) of centres administered intravenous fluids. Where a minimal effusion is present 27/37 (73%) would induce a pneumothorax. Eleven (29%) centres would perform LAT for pleural infection. Only 11/37 (30%) of centres have on-site thoracic surgical support.</p><p><strong>Conclusions: </strong>There is wide variation in LAT practice amongst UK centres. These results support the need for identifying best practice and standardisation of LAT practices, with outcome reporting. These survey results will form the basis of applications to the national and international respiratory societies to develop relevant standards.</p>","PeriodicalId":21048,"journal":{"name":"Respiration","volume":" ","pages":"1-13"},"PeriodicalIF":3.5,"publicationDate":"2025-05-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144174681","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
RespirationPub Date : 2025-05-26DOI: 10.1159/000546043
Thomas Fleischhauer, Elena Biehler, Julia Dorothea Michels-Zetsche, Franziska C Trudzinski, Janina Schubert-Haack, Johanna Forstner, Armin Schneider, Axel Kempa, Biljana Joves, Claus Neurohr, Felix Jf Herth, Joachim Szecsenyi, Michel Wensing
{"title":"Interprofessional collaboration and job satisfaction in German intensive care units - a cross-sectional survey within the PRiVENT project.","authors":"Thomas Fleischhauer, Elena Biehler, Julia Dorothea Michels-Zetsche, Franziska C Trudzinski, Janina Schubert-Haack, Johanna Forstner, Armin Schneider, Axel Kempa, Biljana Joves, Claus Neurohr, Felix Jf Herth, Joachim Szecsenyi, Michel Wensing","doi":"10.1159/000546043","DOIUrl":"https://doi.org/10.1159/000546043","url":null,"abstract":"<p><strong>Background: </strong>The multicentre cluster-randomized PRiVENT study aims to improve weaning of long-term ventilated patients in German intensive care units via a complex interprofessional intervention. To assess perceptions on interprofessional collaboration and job satisfaction among different health professions, a survey was conducted in four clusters, each comprising one weaning centre and 7-12 cooperation hospitals.</p><p><strong>Methods: </strong>Three validated questionnaires were used to measure a) interprofessional socialization (7-level Likert scale), b) interprofessional collaboration (5-level) and c) job satisfaction (7-level). Alongside a descriptive analysis, a subgroup analysis was performed comparing mean scores between physicians and non-physicians and the four clusters. Correlation coefficients were calculated to check for correlations of age group and work experience with interprofessional collaboration and job satisfaction.</p><p><strong>Results: </strong>62 questionnaires were returned by health workers of the intensive care units, corresponding to a response rate of 47%. Respondents rated interprofessional socialization (5.7 ± 0.6 ) and collaboration (3.8 ± 0.6) as good. Job satisfaction was high (5.1 ± 1.0), particularly regarding the collegial environment and variety of work tasks. Satisfaction with physical workload, income, and working hours was lower. Compared to physicians, overall ratings of non-physicians were lower, although the differences were not statistically significant, as were those between clusters. There was a statistically significant positive correlation of age group and work experience with overall job satisfaction.</p><p><strong>Conclusions: </strong>Health workers within PRiVENT are satisfied with their workplace conditions and rate interprofessional collaboration as good. Follow-up surveys will provide insights into the impact of PRiVENT on interprofessional cooperation and job satisfaction.</p>","PeriodicalId":21048,"journal":{"name":"Respiration","volume":" ","pages":"1-18"},"PeriodicalIF":3.5,"publicationDate":"2025-05-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144151546","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
RespirationPub Date : 2025-05-23DOI: 10.1159/000546340
Ju Zou, Jie Li, Xiaoxu Wang, Min Liu, Jiawang Chen, Ling Wang, Yongguo Du, Ruochan Chen
{"title":"Case Report Series and Mini Review on Tuberculosis in IVF-ET Pregnancies: A Call for Vigilant Monitoring and Early Intervention.","authors":"Ju Zou, Jie Li, Xiaoxu Wang, Min Liu, Jiawang Chen, Ling Wang, Yongguo Du, Ruochan Chen","doi":"10.1159/000546340","DOIUrl":"https://doi.org/10.1159/000546340","url":null,"abstract":"<p><strong>Background: </strong>The risk of tuberculosis during pregnancy is significantly increased, and untimely Mycobacterium tuberculosis (M. tuberculosis) treatment during pregnancy increases the risk of perinatal complications and poor fetal prognosis. Hormonal use in vitro fertilization and embryo transfer (IVF-ET) promotes the growth of M. tuberculosis, leading to more severe disease and adverse pregnancy outcomes. However, its clinical characteristics and possible mechanisms of TB infection in pregnant women who conceive by IVF-ET remain unclear. Therefore, we report three cases of young pregnant women diagnosed with TB after IVF-ET and describe their diagnosis and treatment.</p><p><strong>Case presentation: </strong>Three young women (age: 26-31 years) diagnosed with primary infertility underwent IVF-ET treatment. They lacked a history of TB or manifestations of activated TB before transplantation. After presenting with fever, cough, and headache at 5-12 weeks of pregnancy, they were diagnosed with miliary TB, disseminated TB, and tuberculous meningitis, respectively. Initially, the patients were on a daily fixed-dose combination of first-line anti-TB treatment (ATT), which comprised rifampicin, isoniazid, pyrazinamide, and ethambutol, followed by medication adjustment during treatment for 6-12 months. Although all fetuses were lost, the patients achieved optimal outcomes after timely ATT.</p><p><strong>Conclusions: </strong>This report demonstrates the increased risk of TB in pregnant women who conceive by IVF-ET. Therefore, it is important to carefully monitor these women even if they lack a history of or exposure to TB. Accordingly, prompt diagnosis and treatment of TB in these patients is necessary to optimize patient outcomes.</p>","PeriodicalId":21048,"journal":{"name":"Respiration","volume":" ","pages":"1-20"},"PeriodicalIF":3.5,"publicationDate":"2025-05-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144143420","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
RespirationPub Date : 2025-04-29DOI: 10.1159/000546088
Javier Flandes, Lina V Cerchiaro-Torrado, Carlos Disdier, Javier Alfayate, Iker Fernandez-Navamuel, Carlos Augustí, Carmen M Lucena, Francisco Martinez-Muñiz, Virginia Pajares, Felipe Andreo, Carmen Centeno, Carmen Montero, Miguel Ariza, Eduardo Tuta-Quintero, Rocio Gallego, Alfons Torregó, Héctor González, Rosa Cordovilla, Blanca de Vega-Sanchez, Juan Cascón, J Javier García-López, Cristina L García-Gallo, Prudencio Díaz-Agero, Estefanía Luque-Crespo, María Pavón-Masa, Enrique Cases, José Robles, Ana María Uribe-Hernández, Luis F Giraldo-Cadavid
{"title":"Development and Validation of the BQQ Questionnaire for Assessing Bronchoscopists' Perception of Single-use Flexible Bronchoscope Quality.","authors":"Javier Flandes, Lina V Cerchiaro-Torrado, Carlos Disdier, Javier Alfayate, Iker Fernandez-Navamuel, Carlos Augustí, Carmen M Lucena, Francisco Martinez-Muñiz, Virginia Pajares, Felipe Andreo, Carmen Centeno, Carmen Montero, Miguel Ariza, Eduardo Tuta-Quintero, Rocio Gallego, Alfons Torregó, Héctor González, Rosa Cordovilla, Blanca de Vega-Sanchez, Juan Cascón, J Javier García-López, Cristina L García-Gallo, Prudencio Díaz-Agero, Estefanía Luque-Crespo, María Pavón-Masa, Enrique Cases, José Robles, Ana María Uribe-Hernández, Luis F Giraldo-Cadavid","doi":"10.1159/000546088","DOIUrl":"https://doi.org/10.1159/000546088","url":null,"abstract":"<p><strong>Background: </strong>The risk of cross-infections (including SARS-Cov-2) and damage to the flexible bronchoscope has led to the development of single-use flexible bronchoscopes as a cost-effective alternative. It is necessary for the bronchoscopist to evaluate the perception of the quality of these devices to determine if their quality is satisfactory for the user.</p><p><strong>Objective: </strong>Construction and validation of a Bronchoscope Quality Questionnaire (BQQ) to evaluate the quality of the flexible bronchoscope perceived by the bronchoscopist.</p><p><strong>Methods: </strong>We conducted a cross-sectional study in 21 pulmonology centres in Spain. A first version of the BQQ was carried out by a group of experts, the construct validity was evaluated, and a factor analysis reduced the number of items. Feasibility of the BQQ was assessed by a questionnaire, internal consistency by the Cronbach's alpha coefficient and intra- and interrater reliability by the intraclass correlation coefficient (ICC).</p><p><strong>Results: </strong>The final version of the BQQ was composed of six domains and 18 items. The median completion time was five minutes, and it was not difficult to understand the items. Cronbach's alpha was 0.89, the intrarater ICC was 0.70 (95% CI 0.56 to 0.79), and the interrater ICC was 0.64 (95% CI: 0.47 to 0.76).</p><p><strong>Conclusion: </strong>The BQQ showed good feasibility, internal consistency and intra- and interrater reliability, which makes it suitable for evaluating the quality of flexible bronchoscopes perceived by the bronchoscopist.</p>","PeriodicalId":21048,"journal":{"name":"Respiration","volume":" ","pages":"1-15"},"PeriodicalIF":3.5,"publicationDate":"2025-04-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144034575","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}