Renal Replacement Therapy最新文献

{"title":"Humoral response after BNT162b2 vaccine in Japanese hemodialysis patients.","authors":"Ryoichi Miyazaki,&nbsp;Kyoko Miyagi,&nbsp;Misaki Yoshida,&nbsp;Yasunori Suzuki","doi":"10.1186/s41100-022-00452-1","DOIUrl":"https://doi.org/10.1186/s41100-022-00452-1","url":null,"abstract":"<p><strong>Background: </strong>Hemodialysis patients are more likely to be severely affected if infected by COVID-19. Contributing factors include chronic kidney disease, old age, hypertension, type 2 diabetes, heart disease, and cerebrovascular disease. Therefore, action against COVID-19 for hemodialysis patients is an urgent issue. Vaccines are effective in preventing COVID 19 infection. In hemodialysis patients, however, responses to hepatitis B and influenza vaccines are reportedly weak. The BNT162b2 vaccine has shown an efficacy rate of about 95% in the general population, but as far as we know there are only several reports of efficacy data in hemodialysis patients in Japan.</p><p><strong>Methods: </strong>We assessed serum anti-SARS-CoV-2 IgG antibody (Abbott SARS-CoV-2 IgG II Quan) in 185 hemodialysis patients and 109 health care workers. The exclusion criterion was positivity for SARS-CoV-2 IgG antibody before vaccination. Adverse reactions to BNT162b2 vaccine were evaluated through interviews.</p><p><strong>Results: </strong>Following vaccination, 97.6% of the hemodialysis group and 100% of the control group were positive for the anti-spike antibody. The median level of anti-spike antibody was 2,728.7 AU/mL (IQR, 1,024.2-7,688.2 AU/mL) in the hemodialysis group and 10,500 AU/ml (IQR, 9,346.1-2,4500 AU/mL) in the health care workers group. The factors involved in the low response to the BNT152b2 vaccine included old age, low BMI, low Cr index, low nPCR, low GNRI, low lymphocyte count, steroid administration, and complications related to blood disorders.</p><p><strong>Conclusions: </strong>Humoral responses to BNT162b2 vaccine in hemodialysis patients are weaker than in a healthy control sample. Booster vaccination is necessary for hemodialysis patients, especially those showing a weak or non-response to the two-dose BNT162b2 vaccine.<i>Trial registration</i> UMIN, UMIN000047032. Registered 28 February 2022, https://center6.umin.ac.jp/cgi-bin/ctr/ctr_reg_rec.cgi.</p>","PeriodicalId":21028,"journal":{"name":"Renal Replacement Therapy","volume":"9 1","pages":"13"},"PeriodicalIF":1.2,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9939857/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10782882","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Survey of food offered to United Kingdom haemodialysis patients attending for dialysis sessions in main dialysis centres and satellite units and international comparison.","authors":"Andrew Davenport","doi":"10.1186/s41100-023-00466-3","DOIUrl":"https://doi.org/10.1186/s41100-023-00466-3","url":null,"abstract":"<p><strong>Background: </strong>Haemodialysis (HD) patients are at increased risk of frailty, sarcopenia and protein energy wasting, all associated with increased mortality. Most of the dialysis day is taken up with travelling to and from dialysis centres and dialysis treatment. The International Society of Nutrition and Metabolism (ISNM) recommend that meals or supplements should be part of standard clinical practice when patients attending for dialysis.</p><p><strong>Results: </strong>We surveyed adult UK centres to determine the provision of food to dialysis patients in the United Kingdom (UK). A hot meal was provided by six (8.7%) of the 69 UK adult units, although 16 (23.2%) main centres would potentially provide meals to a restricted number of malnourished patients. Forty-seven (68.1%) centres provided sandwiches, although this was restricted in eight main centres, and 26.2% of units did not provide sandwiches to patients in their satellite dialysis centres. Biscuits were the only nutrition routinely offered in 15 (21.7%) of the main dialysis units, 41.3% of satellite units. Meals were more likely to be offered in Northern Ireland and Scotland compared to England, and 38% of the main dialysis units in England, and 58% of their satellite centres did not routinely offer patients a sandwich compared to none or one centre in Wales, Scotland and Northern Ireland.</p><p><strong>Conclusions: </strong>Despite an increasing older, more frail dialysis population in the UK, food provision for dialysis patients has reduced, particularly in England, with < 10% of centres routinely offering hot food, and > 50% of dialysis units now only offering biscuits to their satellite dialysis patients.</p>","PeriodicalId":21028,"journal":{"name":"Renal Replacement Therapy","volume":"9 1","pages":"10"},"PeriodicalIF":1.2,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9900543/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10707871","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Changes in body composition of patients undergoing hemodialysis during the coronavirus disease 2019 pandemic: a retrospective longitudinal study.","authors":"Narumi Fukuzaki,&nbsp;Yuta Suzuki,&nbsp;Juri Uchida,&nbsp;Takuya Nakajima,&nbsp;Shohei Yamamoto,&nbsp;Keigo Imamura,&nbsp;Shun Yoshikoshi,&nbsp;Manae Harada,&nbsp;Ryota Matsuzawa,&nbsp;Kentaro Kamiya,&nbsp;Atsuhiko Matsunaga","doi":"10.1186/s41100-023-00465-4","DOIUrl":"https://doi.org/10.1186/s41100-023-00465-4","url":null,"abstract":"<p><strong>Background: </strong>The spread of coronavirus disease 2019 (COVID-19) has dramatically altered the lifestyles of many people worldwide. Several studies reported that body weight of young adults increased during the COVID-19 pandemic; however, weight loss has been observed in the elderly population. Therefore, trends in body composition due to the COVID-19 pandemic may vary depending on the characteristics of the population. This study aimed to investigate the changes in body mass index (BMI), muscle mass, and fat mass before and during the COVID-19 pandemic among patients undergoing hemodialysis.</p><p><strong>Methods: </strong>In this retrospective longitudinal study, we enrolled 115 clinically stable outpatients (mean age: 65.7 ± 11.2 years, 62.6% men) who underwent hemodialysis thrice a week. Baseline data were collected between April 2019 and March 2020, before the declaration of the COVID-19 emergency by the Japanese government. The follow-up measurements were performed between July 2020 and March 2021 during the COVID-19 pandemic. Patient characteristics, laboratory data, and BMI measurements were collected from the medical records. Muscle mass and fat mass were measured using bioelectrical impedance analysis.</p><p><strong>Results: </strong>BMI and fat mass among the study participants were significantly higher during the COVID-19 pandemic than before the pandemic (<i>p</i> < 0.01), but no significant change in muscle mass was observed. A restricted cubic spline function showed that the increase in BMI appeared to correlate well with fat mass, but not with muscle mass.</p><p><strong>Conclusions: </strong>BMI and fat mass of patients on hemodialysis significantly increased due to preventive measures against the COVID-19 pandemic in Japan. These findings may provide useful information in making nutritional management decisions for patients undergoing hemodialysis during and after the COVID-19 pandemic.</p>","PeriodicalId":21028,"journal":{"name":"Renal Replacement Therapy","volume":"9 1","pages":"12"},"PeriodicalIF":1.2,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9912208/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10752181","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cardiovascular events by different target hemoglobin levels in ESA-hyporesponsive hemodialysis patients: a multicenter, open-label, randomized controlled study","authors":"K. Nitta, T. Kuragano, N. Joki, K. Tsuruya, H. Honda, T. Hamano, Hideki Fujii, Y. Uemura, K. Tsuchiya, Therapies Study Investigators","doi":"10.1186/s41100-022-00450-3","DOIUrl":"https://doi.org/10.1186/s41100-022-00450-3","url":null,"abstract":"","PeriodicalId":21028,"journal":{"name":"Renal Replacement Therapy","volume":" ","pages":"1-10"},"PeriodicalIF":1.2,"publicationDate":"2022-12-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46785880","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effects of ferric citrate hydrate in patients with chronic kidney disease and heart failure: subgroup analysis of a long-term, real-world, post-marketing surveillance study","authors":"Kyoko Ito, Kenjiro Murakami, Ryoichi Yamada, Hiroyuki Susai, Noriaki Nishino","doi":"10.1186/s41100-022-00454-z","DOIUrl":"https://doi.org/10.1186/s41100-022-00454-z","url":null,"abstract":"","PeriodicalId":21028,"journal":{"name":"Renal Replacement Therapy","volume":"8 1","pages":"1-18"},"PeriodicalIF":1.2,"publicationDate":"2022-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43417522","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Invasive aspergillosis in the patient with focal segmental glomerulosclerosis initiating hemodialysis: a case report and mini-review","authors":"Noriaki Sato, H. Yokoi, Mitsuhiro Ichioka, Akira Ishii, T. Matsubara, M. Yanagita","doi":"10.1186/s41100-022-00455-y","DOIUrl":"https://doi.org/10.1186/s41100-022-00455-y","url":null,"abstract":"","PeriodicalId":21028,"journal":{"name":"Renal Replacement Therapy","volume":" ","pages":"1-9"},"PeriodicalIF":1.2,"publicationDate":"2022-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42431795","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"High-flow continuous hemodiafiltration successfully decreased blood pregabalin levels in a patient with severe pregabalin intoxication: a case report","authors":"Takashi Shimazui, N. Kitamura, Kuniyuki Kako, Shinya Iwase, Toshinao Suzuki, S. Hoshino, Hiromi Futagami, K. Kibayashi, Ken‐ichiro Nakao","doi":"10.1186/s41100-022-00449-w","DOIUrl":"https://doi.org/10.1186/s41100-022-00449-w","url":null,"abstract":"","PeriodicalId":21028,"journal":{"name":"Renal Replacement Therapy","volume":" ","pages":"1-5"},"PeriodicalIF":1.2,"publicationDate":"2022-11-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46871206","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Research on the relationship between serum indoxyl sulfate concentration and iron dynamics index in patients with end-stage kidney disease: a cross-sectional study","authors":"Takuya Yoshida, M. Tsujimoto, Sachiyo Kawakami, H. Fujioka, Yuko Irie, Saki Nakatani, A. Iso, Ayaka Sugiyama, Mizuho Miyake, Kazumi Hirato, Rie Tanaka, Tomoko Oda, T. Furukubo, S. Izumi, T. Yamakawa, T. Minegaki, K. Nishiguchi","doi":"10.1186/s41100-022-00444-1","DOIUrl":"https://doi.org/10.1186/s41100-022-00444-1","url":null,"abstract":"","PeriodicalId":21028,"journal":{"name":"Renal Replacement Therapy","volume":" ","pages":"1-8"},"PeriodicalIF":1.2,"publicationDate":"2022-11-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46857416","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Long-term body composition changes in patients undergoing hemodialysis: a single-center retrospective study","authors":"Yumi Seto, Mina Kimura, Tomohito Matsunaga, Eishi Miyasita, Y. Kanno","doi":"10.1186/s41100-022-00448-x","DOIUrl":"https://doi.org/10.1186/s41100-022-00448-x","url":null,"abstract":"","PeriodicalId":21028,"journal":{"name":"Renal Replacement Therapy","volume":" ","pages":"1-8"},"PeriodicalIF":1.2,"publicationDate":"2022-11-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43805528","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Relationship between resistance index and recirculation rate in vascular access","authors":"Katsuyuki Umei, Naohiro Toda, Juri Izumi, Yuriko Umeda, Mari Iwata, Kazuhide Nakanishi, T. Komiya","doi":"10.1186/s41100-022-00446-z","DOIUrl":"https://doi.org/10.1186/s41100-022-00446-z","url":null,"abstract":"","PeriodicalId":21028,"journal":{"name":"Renal Replacement Therapy","volume":" ","pages":"1-7"},"PeriodicalIF":1.2,"publicationDate":"2022-11-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46586037","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}