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Quarterly journal of experimental physiology and cognate medical sciences最新文献

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Secretory, motor and vascular effects in the sublingual gland of the rat caused by autonomic nerve stimulation. 自主神经刺激对大鼠舌下腺分泌、运动和血管的影响。
Quarterly journal of experimental physiology and cognate medical sciences Pub Date : 1978-01-01 DOI: 10.1113/expphysiol.1978.sp002415
D Templeton, A Thulin
{"title":"Secretory, motor and vascular effects in the sublingual gland of the rat caused by autonomic nerve stimulation.","authors":"D Templeton,&nbsp;A Thulin","doi":"10.1113/expphysiol.1978.sp002415","DOIUrl":"https://doi.org/10.1113/expphysiol.1978.sp002415","url":null,"abstract":"<p><p>The influence of the autonomic nerves on sublingual glands of rats was studied. Stimulation of the chorda-lingual nerve evoked a lively flow of saliva and was also thought to contract the myoepithelial cells in the gland. Sympathetic nerve stimulation, on the other hand, usually evoked no secretion and did not cause any motor responses in the sublingual gland. The glandular blood flow was increased by chorda-lingual nerve stimulation, and this vasodilatation persisted also when atropine had been administered. Sympathetic nerve stimulation decreased the sublingual blood flow; this vasoconstrictor effect was mediated via activation of alpha-adrenoceptors.</p>","PeriodicalId":20764,"journal":{"name":"Quarterly journal of experimental physiology and cognate medical sciences","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"1978-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1113/expphysiol.1978.sp002415","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"11456906","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 29
The absorptive viability of isolated intestine prepared from dead animals. 动物死亡制备的离体肠的吸收能力。
Quarterly journal of experimental physiology and cognate medical sciences Pub Date : 1978-01-01 DOI: 10.1113/expphysiol.1978.sp002420
M L Gardner
{"title":"The absorptive viability of isolated intestine prepared from dead animals.","authors":"M L Gardner","doi":"10.1113/expphysiol.1978.sp002420","DOIUrl":"https://doi.org/10.1113/expphysiol.1978.sp002420","url":null,"abstract":"<p><p>Glucose and water absorption rates are much lower (50%) in isolated perfused rat small intestine when the animals are killed by stunning or ether before removal of the intestine than when the animal is maintained alive under light ether anaesthesia throughout the setting-up procedure.</p>","PeriodicalId":20764,"journal":{"name":"Quarterly journal of experimental physiology and cognate medical sciences","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"1978-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1113/expphysiol.1978.sp002420","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"11456632","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 16
Effect of high fluoride intake on haematological aspects of the mouse. 高氟摄入对小鼠血液学方面的影响。
Quarterly journal of experimental physiology and cognate medical sciences Pub Date : 1978-01-01 DOI: 10.1113/expphysiol.1978.sp002418
A W Mehdi, M T Ridha, A A Al-Kafawi, M H Injidi
{"title":"Effect of high fluoride intake on haematological aspects of the mouse.","authors":"A W Mehdi,&nbsp;M T Ridha,&nbsp;A A Al-Kafawi,&nbsp;M H Injidi","doi":"10.1113/expphysiol.1978.sp002418","DOIUrl":"https://doi.org/10.1113/expphysiol.1978.sp002418","url":null,"abstract":"<p><p>The effect of feeding adult Swiss albino mice of both sexes a diet supplemented with 0, 125, 250 and 500 parts/10(6) of fluoride for four and eight week periods on haemoglobin concentration (Hb), packed cell volume (PCV) and mean corpuscular haemoglobin concentration (MCHC) was investigated. Values of the three parameters were significantly lowered at both periods in the treated groups as compared with the controls. The extent of reduction in these values was, in general, dependent on the dose of supplemented dietary fluoride. Clinical symptoms were not observed before the end of the sixth week. However, appearance of the symptoms did not change the trend of variations in Hb, PCV and MCHC values. The reduced values could be the result of lowered haemoglobin synthesis and erythropoiesis. It was suggested that these haematological indices could serve to detect preclinical effects of high fluoride intake with an added dose of as low as 125 parts/10(6), or even less, for a period of four weeks or probably earlier.</p>","PeriodicalId":20764,"journal":{"name":"Quarterly journal of experimental physiology and cognate medical sciences","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"1978-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1113/expphysiol.1978.sp002418","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"11456630","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 4
Effect of sub-diaphragmatic vagotomy on gastric mucosal mast cell population in pylorus ligated rats. 膈下迷走神经切开术对幽门结扎大鼠胃粘膜肥大细胞群的影响。
Quarterly journal of experimental physiology and cognate medical sciences Pub Date : 1978-01-01 DOI: 10.1113/expphysiol.1978.sp002419
A K Ganguly, S S Sathiamoorthy, O P Bhatnagar
{"title":"Effect of sub-diaphragmatic vagotomy on gastric mucosal mast cell population in pylorus ligated rats.","authors":"A K Ganguly,&nbsp;S S Sathiamoorthy,&nbsp;O P Bhatnagar","doi":"10.1113/expphysiol.1978.sp002419","DOIUrl":"https://doi.org/10.1113/expphysiol.1978.sp002419","url":null,"abstract":"<p><p>Gastric mucosal mast cell population was studied following sub-diaphragmatic vagotomy in albino rats, 6 and 12 h after pylorus ligation. Sub-diaphragmatic vagotomy significantly increased the gastric mucosal mast cell population in both 6 and 12 h groups, the increase being more in the latter. The results suggest that the vagal impulses act on the gastric mucosal mast cells causing their degranulation. Following vagotomy the contents stay bound within the mast cells. Increase in mast cell population with the longer experimental situation was possibly due to the continuation of normal turnover of the mast cells in the gastric mucosa. The present study, however, does not lead to a conclusion that the vagal influence on mast cell population is similar throughout the gastro-intestinal tract.</p>","PeriodicalId":20764,"journal":{"name":"Quarterly journal of experimental physiology and cognate medical sciences","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"1978-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1113/expphysiol.1978.sp002419","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"11456631","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 17
Post prandial changes in parotid salivary secretion and plasma osmolality and the effects of intravenous of saline solutions. 餐后腮腺唾液分泌和血浆渗透压的变化及静脉注射生理盐水的影响。
Quarterly journal of experimental physiology and cognate medical sciences Pub Date : 1978-01-01 DOI: 10.1113/expphysiol.1978.sp002410
D H Carr, D A Titchen
{"title":"Post prandial changes in parotid salivary secretion and plasma osmolality and the effects of intravenous of saline solutions.","authors":"D H Carr,&nbsp;D A Titchen","doi":"10.1113/expphysiol.1978.sp002410","DOIUrl":"https://doi.org/10.1113/expphysiol.1978.sp002410","url":null,"abstract":"","PeriodicalId":20764,"journal":{"name":"Quarterly journal of experimental physiology and cognate medical sciences","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"1978-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1113/expphysiol.1978.sp002410","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"11456902","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 24
Spontaneous and bile salt stimulated bile secretion in the Adelie penguin (Pygoscelis adeliae). 自发盐和胆盐刺激阿德利企鹅的胆汁分泌。
Quarterly journal of experimental physiology and cognate medical sciences Pub Date : 1978-01-01 DOI: 10.1113/expphysiol.1978.sp002412
C J Andrews
{"title":"Spontaneous and bile salt stimulated bile secretion in the Adelie penguin (Pygoscelis adeliae).","authors":"C J Andrews","doi":"10.1113/expphysiol.1978.sp002412","DOIUrl":"https://doi.org/10.1113/expphysiol.1978.sp002412","url":null,"abstract":"The flow rate and ionic composition of bile during spontaneous secretion were measured in anaesthetized penguins in which the enterohepatic circulation had been interrupted and with i.v. injection of saline to replace secretory loss. During the first two hours the rate of flow increased, and then remained relatively constant for a further two and a half hours. During this time the concentration of bile salt fell, but the concentrations of other ions showed small fluctuations only. Sodium taurocholate increased the rate of bile flow and the excretion of ions, except that of bicarbonate. Sodium taurolithocholate initially produced cholestasis but later apparently increased bile flow and had an overall choleretic effect. It is suggested that the active excretion of bicarbonate ions by the bile ducts is the predominant regulator of bile secretion in the penguin.","PeriodicalId":20764,"journal":{"name":"Quarterly journal of experimental physiology and cognate medical sciences","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"1978-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1113/expphysiol.1978.sp002412","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"11456903","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The effects of urea infusion on glomerular filtration rate and renal plasma flow in sheep fed low and high protein diets. 尿素输注对低、高蛋白饲粮绵羊肾小球滤过率和肾血浆流量的影响。
Quarterly journal of experimental physiology and cognate medical sciences Pub Date : 1978-01-01 DOI: 10.1113/expphysiol.1978.sp002417
N Ergene, E C Pickering
{"title":"The effects of urea infusion on glomerular filtration rate and renal plasma flow in sheep fed low and high protein diets.","authors":"N Ergene,&nbsp;E C Pickering","doi":"10.1113/expphysiol.1978.sp002417","DOIUrl":"https://doi.org/10.1113/expphysiol.1978.sp002417","url":null,"abstract":"<p><p>Reducing the dietary N intake of sheep resulted in a significant fall in GFR with no change in RPF. Intravenous of urea for 19-46 h had no effect on the high protein diet but on the low protein diet GFR and FF were increased to values approaching those observed on the high protein diet. On the low protein diet GFR was unaffected by infusion of urea for 4 h or of saline alone for 30 h. It is suggested that the observed changes in GFR are associated with changes in the quantity of protein passing to the abomasum and small intestine.</p>","PeriodicalId":20764,"journal":{"name":"Quarterly journal of experimental physiology and cognate medical sciences","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"1978-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1113/expphysiol.1978.sp002417","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"11456908","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 11
Prolonged effects of a post-synaptic blocking fraction of Naja siamensis venom of skeletal muscle of the mouse. 小鼠骨骼肌突触后阻断部分的作用。
Quarterly journal of experimental physiology and cognate medical sciences Pub Date : 1978-01-01 DOI: 10.1113/expphysiol.1978.sp002413
D A Tonge
{"title":"Prolonged effects of a post-synaptic blocking fraction of Naja siamensis venom of skeletal muscle of the mouse.","authors":"D A Tonge","doi":"10.1113/expphysiol.1978.sp002413","DOIUrl":"https://doi.org/10.1113/expphysiol.1978.sp002413","url":null,"abstract":"<p><p>A sublethal dose of a post-synaptic blocking fraction of Naja siamensis venom was injected into the soleus muscle of the mouse inhibiting neuromuscular transmission for 2-3 days. The paralysed soleus muscle behaved as if denervated, developing extra-junctional sensitivity to acetylcholine and accepting innervation by an implanted foreign nerve. Since the only known action of the post-synaptic blocking fraction of this venom is due to its affinity to acetylcholine receptors, the results suggest that the spread in the sensitivity of muscle fibres to acetylcholine and their ability to accept a foreign nerve is a consequence of neuromuscular blockade.</p>","PeriodicalId":20764,"journal":{"name":"Quarterly journal of experimental physiology and cognate medical sciences","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"1978-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1113/expphysiol.1978.sp002413","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"11456904","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 7
The effects of reducing dietary nitrogen and of increasing sodium chloride intake on urea excretion and reabsorption and on urine osmolality in sheep. 饲粮减少氮和增加氯化钠摄入量对绵羊尿素排泄和重吸收及尿渗透压的影响。
Quarterly journal of experimental physiology and cognate medical sciences Pub Date : 1978-01-01 DOI: 10.1113/expphysiol.1978.sp002416
N Ergene, E C Pickering
{"title":"The effects of reducing dietary nitrogen and of increasing sodium chloride intake on urea excretion and reabsorption and on urine osmolality in sheep.","authors":"N Ergene,&nbsp;E C Pickering","doi":"10.1113/expphysiol.1978.sp002416","DOIUrl":"https://doi.org/10.1113/expphysiol.1978.sp002416","url":null,"abstract":"<p><p>Renal responses to reducing dietary nitrogen were studied in four ewes during intravenous infusion of arginine vasopressin. The fall in urea excretion and in plasma urea concentration was accompanied by significant reduction in GFR and in urine osmolality. The fraction of filtered urea reabsorbed increased despite reduction in the urea U/P concentration ratio and this increase was sustained when the urea U/P ratio was further reduced at higher urine flows observed when the drinking water was replaced with saline. This procedure also sustained the RPF which in the absence of additional salt was significantly reduced on the low protein diet. It is suggested that the fall in GFR and the increase in the fraction of filtered urea reabsorbsed may contribute to nitrogen economy and that the increase in fractional reabsorption and the reduction in urine osmolality on the low protein diet provided evidence of active reabsorption of urea by renal tubules.</p>","PeriodicalId":20764,"journal":{"name":"Quarterly journal of experimental physiology and cognate medical sciences","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"1978-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1113/expphysiol.1978.sp002416","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"11456907","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 21
The stereo-specificity and temperature-dependence of the permeability of human erythrocytes to aldoses. 人红细胞对醛糖渗透性的立体特异性和温度依赖性。
Quarterly journal of experimental physiology and cognate medical sciences Pub Date : 1973-04-01
R B Fisher, I A Nimmo
{"title":"The stereo-specificity and temperature-dependence of the permeability of human erythrocytes to aldoses.","authors":"R B Fisher,&nbsp;I A Nimmo","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":20764,"journal":{"name":"Quarterly journal of experimental physiology and cognate medical sciences","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"1973-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"15586912","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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