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Progress in medicinal chemistry最新文献

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Calcitonin gene-related peptide receptor antagonists for the treatment of migraine. 降钙素基因相关肽受体拮抗剂治疗偏头痛。
Progress in medicinal chemistry Pub Date : 2009-01-01 DOI: 10.1016/S0079-6468(08)00201-4
Theresa M Williams, Christopher S Burgey, Christopher A Salvatore
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引用次数: 2
Progress in the design and development of phosphoinositide 3-kinase (PI3K) inhibitors for the treatment of chronic diseases. 用于治疗慢性疾病的磷酸肌苷3-激酶(PI3K)抑制剂的设计和开发进展。
Progress in medicinal chemistry Pub Date : 2009-01-01 DOI: 10.1016/s0079-6468(09)04803-6
Stephen Shuttleworth, Franck Silva, Cyrille Tomassi, Alexander Cecil, Thomas Hill, Helen Rogers, Paul Townsend
{"title":"Progress in the design and development of phosphoinositide 3-kinase (PI3K) inhibitors for the treatment of chronic diseases.","authors":"Stephen Shuttleworth, Franck Silva, Cyrille Tomassi, Alexander Cecil, Thomas Hill, Helen Rogers, Paul Townsend","doi":"10.1016/s0079-6468(09)04803-6","DOIUrl":"https://doi.org/10.1016/s0079-6468(09)04803-6","url":null,"abstract":"","PeriodicalId":20755,"journal":{"name":"Progress in medicinal chemistry","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2009-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/s0079-6468(09)04803-6","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"30163919","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 11
The identification of and rationale for drugs which act at the motilin receptor. 对运动素受体起作用的药物的鉴定和原理。
Progress in medicinal chemistry Pub Date : 2009-01-01 DOI: 10.1016/s0079-6468(09)04802-4
Susan M Westaway, Gareth J Sanger
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引用次数: 18
PDE4 inhibitors - a review of the current field. PDE4抑制剂-当前领域综述。
Progress in medicinal chemistry Pub Date : 2009-01-01 DOI: 10.1016/S0079-6468(08)00202-6
Neil J Press, Katharine H Banner
{"title":"PDE4 inhibitors - a review of the current field.","authors":"Neil J Press, Katharine H Banner","doi":"10.1016/S0079-6468(08)00202-6","DOIUrl":"https://doi.org/10.1016/S0079-6468(08)00202-6","url":null,"abstract":"","PeriodicalId":20755,"journal":{"name":"Progress in medicinal chemistry","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2009-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S0079-6468(08)00202-6","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"28079105","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 58
Endothelin receptor antagonists: status and learning 20 years on. 内皮素受体拮抗剂的现状和研究进展。
Progress in medicinal chemistry Pub Date : 2009-01-01 DOI: 10.1016/S0079-6468(08)00205-1
Michael J Palmer
{"title":"Endothelin receptor antagonists: status and learning 20 years on.","authors":"Michael J Palmer","doi":"10.1016/S0079-6468(08)00205-1","DOIUrl":"https://doi.org/10.1016/S0079-6468(08)00205-1","url":null,"abstract":"","PeriodicalId":20755,"journal":{"name":"Progress in medicinal chemistry","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2009-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S0079-6468(08)00205-1","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"28079108","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 23
Cytochrome P450 metabolism and inhibition: analysis for drug discovery. 细胞色素P450代谢与抑制:药物发现分析。
Progress in medicinal chemistry Pub Date : 2009-01-01 DOI: 10.1016/S0079-6468(08)00206-3
Barry C Jones, Donald S Middleton, Kuresh Youdim
{"title":"Cytochrome P450 metabolism and inhibition: analysis for drug discovery.","authors":"Barry C Jones, Donald S Middleton, Kuresh Youdim","doi":"10.1016/S0079-6468(08)00206-3","DOIUrl":"https://doi.org/10.1016/S0079-6468(08)00206-3","url":null,"abstract":"","PeriodicalId":20755,"journal":{"name":"Progress in medicinal chemistry","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2009-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S0079-6468(08)00206-3","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"28079109","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 12
Alpha7 nicotinic acetylcholine receptor agonists and positive allosteric modulators. α 7烟碱乙酰胆碱受体激动剂和阳性变构调节剂。
Progress in medicinal chemistry Pub Date : 2008-01-01 DOI: 10.1016/S0079-6468(07)00003-3
Andrew P Lightfoot, James N C Kew, John Skidmore
{"title":"Alpha7 nicotinic acetylcholine receptor agonists and positive allosteric modulators.","authors":"Andrew P Lightfoot, James N C Kew, John Skidmore","doi":"10.1016/S0079-6468(07)00003-3","DOIUrl":"https://doi.org/10.1016/S0079-6468(07)00003-3","url":null,"abstract":"","PeriodicalId":20755,"journal":{"name":"Progress in medicinal chemistry","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2008-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S0079-6468(07)00003-3","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"27355613","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 37
Small molecule bradykinin B1 receptor antagonists as potential therapeutic agents for pain. 小分子缓激肽B1受体拮抗剂作为潜在的疼痛治疗剂。
Progress in medicinal chemistry Pub Date : 2008-01-01 DOI: 10.1016/S0079-6468(07)00004-5
Jian Jeffrey Chen, Kaustav Biswas
{"title":"Small molecule bradykinin B1 receptor antagonists as potential therapeutic agents for pain.","authors":"Jian Jeffrey Chen, Kaustav Biswas","doi":"10.1016/S0079-6468(07)00004-5","DOIUrl":"https://doi.org/10.1016/S0079-6468(07)00004-5","url":null,"abstract":"","PeriodicalId":20755,"journal":{"name":"Progress in medicinal chemistry","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2008-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S0079-6468(07)00004-5","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"27355614","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 7
Inhibitors of 11beta-hydroxysteroid dehydrogenase type 1. 11 -羟基类固醇脱氢酶1型抑制剂。
Progress in medicinal chemistry Pub Date : 2008-01-01 DOI: 10.1016/S0079-6468(07)00002-1
Xiangdong Su, Nigel Vicker, Barry V L Potter
{"title":"Inhibitors of 11beta-hydroxysteroid dehydrogenase type 1.","authors":"Xiangdong Su, Nigel Vicker, Barry V L Potter","doi":"10.1016/S0079-6468(07)00002-1","DOIUrl":"https://doi.org/10.1016/S0079-6468(07)00002-1","url":null,"abstract":"","PeriodicalId":20755,"journal":{"name":"Progress in medicinal chemistry","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2008-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S0079-6468(07)00002-1","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"27355612","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 5
Appropriate selection of biochemical targets is one of the most important driver of cost-effectiveness in the discovery of new medicines. Preface. 适当选择生化靶点是新药发现过程中最重要的成本效益驱动因素之一。前言。
Progress in medicinal chemistry Pub Date : 2008-01-01 DOI: 10.1016/S0079-6468(07)00008-2
G Lawton, D R Witty
{"title":"Appropriate selection of biochemical targets is one of the most important driver of cost-effectiveness in the discovery of new medicines. Preface.","authors":"G Lawton, D R Witty","doi":"10.1016/S0079-6468(07)00008-2","DOIUrl":"https://doi.org/10.1016/S0079-6468(07)00008-2","url":null,"abstract":"","PeriodicalId":20755,"journal":{"name":"Progress in medicinal chemistry","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2008-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S0079-6468(07)00008-2","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"27355610","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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