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Psychopathology in Adults with Co-occurring Avoidant/Restrictive Food Intake Disorder (ARFID) and Higher Weight. 伴发回避/限制性食物摄入障碍(ARFID)和体重增高的成人精神病理。
IF 22.8 1区 医学
Psychotherapy and Psychosomatics Pub Date : 2025-07-22 DOI: 10.1159/000547450
Anne-Kathrin Merz,Lena Kramer,Alexander Nettlau,Anja Hilbert,Ricarda Schmidt
{"title":"Psychopathology in Adults with Co-occurring Avoidant/Restrictive Food Intake Disorder (ARFID) and Higher Weight.","authors":"Anne-Kathrin Merz,Lena Kramer,Alexander Nettlau,Anja Hilbert,Ricarda Schmidt","doi":"10.1159/000547450","DOIUrl":"https://doi.org/10.1159/000547450","url":null,"abstract":"INTRODUCTIONAvoidant/restrictive food intake disorder (ARFID) occurs in individuals across all weight ranges and age groups. While previous studies primarily focused on children and individuals with underweight, research on ARFID in adults with higher weight is virtually non-existent. Therefore, this study aimed to examine whether adults with (1) ARFID symptoms and (2) ARFID diagnosis differ clinically based on weight status (underweight, normal weight, overweight/obesity).METHODSAdults from the population participated in an online survey and optional clinical interview to verify ARFID diagnostic criteria. Data from 369 adults with ARFID symptoms (online survey) and 77 adults with ARFID diagnosis (interview) were analyzed.RESULTSOverweight/obesity was present in 34% of the online (30 ± 9 years, 77% female) and 39% of the interview sample (29 ± 8 years, 62% female). Adults with both ARFID symptoms and ARFID diagnosis and overweight/obesity showed less lack of interest in eating, higher eating disorder psychopathology, and more metabolic comorbidities compared to those with underweight or normal weight. Additionally, adults with ARFID and overweight/obesity exhibited more psychosocial impairment than those with underweight (100% vs. 65%), but no weight loss due to restricted food intake. There were no group differences in terms of food neophobia, smell and texture sensitivities, and depressive symptoms.CONCLUSIONThis study provides a first detailed analysis of ARFID in adults as a function of weight status, emphasizing its relevance for diagnosis and treatment of ARFID. Future longitudinal studies are needed to explore the role of ARFID in the development and management of higher weight.","PeriodicalId":20744,"journal":{"name":"Psychotherapy and Psychosomatics","volume":"52 1","pages":"1-23"},"PeriodicalIF":22.8,"publicationDate":"2025-07-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144684206","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Assessing exposure to childhood adversity in adults: A systematic review of validated self-report childhood adversity questionnaires. 评估成人童年逆境暴露:一项有效的自我报告童年逆境问卷的系统回顾。
IF 22.8 1区 医学
Psychotherapy and Psychosomatics Pub Date : 2025-07-22 DOI: 10.1159/000547529
Franziska Mosler,Aikaterini Christogianni,Sam Singleton,Tim G Hales,Janine Rennie,Lesley A Colvin,Line Caes
{"title":"Assessing exposure to childhood adversity in adults: A systematic review of validated self-report childhood adversity questionnaires.","authors":"Franziska Mosler,Aikaterini Christogianni,Sam Singleton,Tim G Hales,Janine Rennie,Lesley A Colvin,Line Caes","doi":"10.1159/000547529","DOIUrl":"https://doi.org/10.1159/000547529","url":null,"abstract":"Children exposed to adverse experiences (ACEs) are more likely to experience mental health problems in adulthood. However, ACE assessment is highly heterogeneous, hampering widespread screening and trauma-informed care provision. We aimed to systematically identify and critically evaluate all validated, self-report ACE questionnaires, working with people with lived experience (PWLE). The review followed PRISMA guidelines to systematically search databases for validated self-report measures, completed by adults, assessing at least two ACEs. Articles were excluded if they were not written in English, were not original articles, assessed poor childhood health or adverse experiences happening in adulthood, and/or only assessed one ACE. Psychometric properties were evaluated using Cohen's criteria for evidence-based assessments, the COSMIN checklist, and a content validity form co-designed with PWLE. We identified 112 eligible studies covering 31 ACE questionnaires. Cohen's criteria classified 9 questionnaires as \"well-established\" and 2 as \"approaching well-established\". No questionnaire was rated as \"sufficient\" quality across all the COSMIN measurement properties. The ACE Study-questionnaire, Childhood Experiences Survey (CES) and the ACE-International Questionnaire had the highest number of properties rated as sufficient. The Childhood Trauma Questionnaire-Short Form (CTQ-SF) was most frequently evaluated but received \"insufficient\" ratings across all measurement properties. PWLE scored content validity highest for the CES. Consequently, no ACE questionnaires received good psychometric ratings, with the most widely used questionnaire (CTQ-SF) not performing well, which has implications for selecting an appropriate instrument. With increasing emphasis on trauma-informed health care, there is an urgent need to co-develop ACE questionnaires with PWLE to balance content validity with usability.","PeriodicalId":20744,"journal":{"name":"Psychotherapy and Psychosomatics","volume":"15 1","pages":""},"PeriodicalIF":22.8,"publicationDate":"2025-07-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144684205","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The Effects of Digital Cognitive Behavioral Therapy for Insomnia in Chronic Pain: A Randomized Controlled Trial. 数字认知行为疗法对慢性疼痛患者失眠的影响:一项随机对照试验。
IF 22.8 1区 医学
Psychotherapy and Psychosomatics Pub Date : 2025-07-15 DOI: 10.1159/000547436
Jennifer Schuffelen,Leonie F Maurer,Annika Gieselmann
{"title":"The Effects of Digital Cognitive Behavioral Therapy for Insomnia in Chronic Pain: A Randomized Controlled Trial.","authors":"Jennifer Schuffelen,Leonie F Maurer,Annika Gieselmann","doi":"10.1159/000547436","DOIUrl":"https://doi.org/10.1159/000547436","url":null,"abstract":"INTRODUCTIONManaging chronic pain is a significant healthcare challenge requiring a multimodal approach. The frequent presence of comorbid insomnia and its bidirectional relationship with pain complicates treatment. This study tested whether adding digital cognitive behavioral therapy for insomnia (dCBT-I) to standard chronic pain treatment improves symptoms compared to a waitlist control (WLC).METHODSParticipants with chronic pain and insomnia were randomized (1:1) to dCBT-I or WLC. Assessments occurred at baseline, eight, and 24 weeks post-randomization. The primary outcome was insomnia severity (Insomnia Severity Index; ISI). Secondary outcomes included sleep- and pain-related symptoms, well-being, and dreams. Linear mixed models assessed between-group differences.RESULTSA total of 207 participants (182 women, mean age=51.96±12.97 years) were randomized to dCBT-I (n=103) or WLC (n=104). The dCBT-I group showed large improvements in insomnia severity versus WLC at both eight (-4.36, p<.001; d=-1.18) and 24 weeks (-4.88, p<.001; d=-1.32). Pain-related impairments and life control also improved, favoring dCBT-I (ds=0.22-0.35). Moderate-to-large effects were observed for secondary outcomes, including daytime sleepiness, fatigue, and dysfunctional sleep beliefs (ds=0.47-1.12).CONCLUSIONdCBT-I effectively reduces insomnia severity in individuals with chronic pain and insomnia. Improvements in chronic pain symptoms highlight its potential as a scalable, evidence-based intervention for multimodal pain management.","PeriodicalId":20744,"journal":{"name":"Psychotherapy and Psychosomatics","volume":"3 1","pages":"1-35"},"PeriodicalIF":22.8,"publicationDate":"2025-07-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144640206","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Long-Term Effects of Cognitive Behavioral Therapy on Sickness Absence and Cognitive Functioning in Patients with Stress-Related Disorders: Secondary Results from a Randomized Clinical Trial. 认知行为疗法对应激相关疾病患者缺勤和认知功能的长期影响:一项随机临床试验的次要结果
IF 22.8 1区 医学
Psychotherapy and Psychosomatics Pub Date : 2025-07-08 DOI: 10.1159/000547266
Ludwig Franke Föyen,Victoria Sennerstam,Evelina Kontio,Mats Lekander,Erik Hedman-Lagerlöf,Elin Lindsäter
{"title":"Long-Term Effects of Cognitive Behavioral Therapy on Sickness Absence and Cognitive Functioning in Patients with Stress-Related Disorders: Secondary Results from a Randomized Clinical Trial.","authors":"Ludwig Franke Föyen,Victoria Sennerstam,Evelina Kontio,Mats Lekander,Erik Hedman-Lagerlöf,Elin Lindsäter","doi":"10.1159/000547266","DOIUrl":"https://doi.org/10.1159/000547266","url":null,"abstract":"Introduction Stress-related disorders, including adjustment disorder and exhaustion disorder, are associated with cognitive complaints and prolonged sickness absence (SA). This study evaluated the effects of cognitive behavioral therapy (CBT) compared with an active control treatment (entitled General Health Promotion; GHP) on these outcomes and examined the association between cognitive impairment and SA. Methods In this randomized clinical trial, 300 participants were randomized to CBT or GHP. SA data from the Swedish Social Insurance register were collected from one year before to one year after treatment. Cognitive functioning, assessed via a validated test battery, was measured at baseline, posttreatment, and one-year follow-up (1YFU). Hurdle negative binomial models evaluated SA and linear mixed-effects models analyzed cognitive outcomes. Results CBT and GHP had comparable effects on SA and cognitive functioning with no significant between-group effects (all p > .05). Analyzing effects across the entire sample, the number of SA days among those with any SA did not significantly change (p = .946) but the likelihood of having any SA decreased significantly by the 1YFU (OR = .92, 95% CI [.87, .96], p < .001). Independent of treatment group, overall cognitive functioning improved both posttreatment (d = -.42, 95% CI [-.6, -.25], p < .001) and at 1YFU (d = -.72, 95% CI [-.91, -.54], p < .001). Improvements in cognitive functioning pre to posttreatment were associated with fewer SA days at the 1YFU (IRR = .54, 95% CI [.33, .87], p = .01). Conclusion This study found no specific effect of CBT on SA or cognitive functioning for individuals with stress-related disorders. Cognitive functioning improved regardless of treatment. Early support before SA initiation is likely important to prevent long-term SA.","PeriodicalId":20744,"journal":{"name":"Psychotherapy and Psychosomatics","volume":"65 1","pages":"1-24"},"PeriodicalIF":22.8,"publicationDate":"2025-07-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144586626","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Research, Relevance and Responsibility - for Psychotherapy and Psychosomatics. 心理治疗和身心学的研究、相关性和责任。
IF 22.8 1区 医学
Psychotherapy and Psychosomatics Pub Date : 2025-07-07 DOI: 10.1159/000547206
Stephan Zipfel
{"title":"Research, Relevance and Responsibility - for Psychotherapy and Psychosomatics.","authors":"Stephan Zipfel","doi":"10.1159/000547206","DOIUrl":"https://doi.org/10.1159/000547206","url":null,"abstract":"","PeriodicalId":20744,"journal":{"name":"Psychotherapy and Psychosomatics","volume":"27 1","pages":"1-7"},"PeriodicalIF":22.8,"publicationDate":"2025-07-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144578598","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Assessing psychomotor disturbances among mental disorders: A systematic review and meta-analysis. 评估精神障碍中的精神运动障碍:一项系统综述和荟萃分析。
IF 22.8 1区 医学
Psychotherapy and Psychosomatics Pub Date : 2025-06-27 DOI: 10.1159/000546909
Liang-Yuan Song,Zhen Lyu,Ji-Yu Xie,Yi Zhang,Di Zhao,Antao Chen,Taicheng Huang,Ti-Fei Yuan
{"title":"Assessing psychomotor disturbances among mental disorders: A systematic review and meta-analysis.","authors":"Liang-Yuan Song,Zhen Lyu,Ji-Yu Xie,Yi Zhang,Di Zhao,Antao Chen,Taicheng Huang,Ti-Fei Yuan","doi":"10.1159/000546909","DOIUrl":"https://doi.org/10.1159/000546909","url":null,"abstract":"Psychomotor disturbances (PmD) emerge as common symptoms in many psychiatric diseases. However, currently it lacks a systematic description of PmD among different mental disorders, largely due to the heterogeneity of PmD manifestations. Here we conducted a systematic review and meta-analysis to investigate this question. The initial literature search covered the period from the emergence of the concept of \"Psychomotor\" (1937) to June 27, 2024, which identified 5,701 relevant articles, then purified into 35 cross-sectional studies encompassing five types of mental disorders with 1,828 participants for further analyses. Our results suggest that patients with various mental disorders may commonly exhibit psychomotor retardation (PmR), with subgroup analyses showing effect sizes ranging from -0.32 to -2.31 across five mental disorder types. Moreover, there is preliminary evidence that patients exhibiting PmR may also experience cognitive impairments compared to healthy controls. In sum, our results indicated that PmD may involve in clinical manifestations of different mental disorders.","PeriodicalId":20744,"journal":{"name":"Psychotherapy and Psychosomatics","volume":"19 1","pages":"1-21"},"PeriodicalIF":22.8,"publicationDate":"2025-06-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144521030","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Comparative Efficacy and Safety of Benzodiazepines in the Treatment of Patients with Generalized Anxiety Disorder: A Systematic Review and Network Meta-Analysis. 苯二氮卓类药物治疗广泛性焦虑症患者的比较疗效和安全性:系统综述和网络荟萃分析。
IF 16.3 1区 医学
Psychotherapy and Psychosomatics Pub Date : 2025-06-20 DOI: 10.1159/000546269
Hélder Fernandes, Catarina Novais, Bernardo Sousa-Pinto, Patrício Soares-da-Silva, Luís Filipe Azevedo
{"title":"Comparative Efficacy and Safety of Benzodiazepines in the Treatment of Patients with Generalized Anxiety Disorder: A Systematic Review and Network Meta-Analysis.","authors":"Hélder Fernandes, Catarina Novais, Bernardo Sousa-Pinto, Patrício Soares-da-Silva, Luís Filipe Azevedo","doi":"10.1159/000546269","DOIUrl":"10.1159/000546269","url":null,"abstract":"<p><strong>Introduction: </strong>Guidelines recommend that benzodiazepines (BZDs) might be used as an add-on to antidepressant therapy during the first weeks of treatment of generalized anxiety disorder (GAD) or as a first-line and stand-alone. Our aim was to evaluate the comparative efficacy and safety of individual BZD in the treatment of patients with GAD.</p><p><strong>Methods: </strong>In this systematic review and network meta-analysis, we included randomized controlled trials including adults (≥18 years) with GAD and comparing BZD against placebo or an active intervention. We assessed the certainty of evidence using the confidence in network meta-analysis (CINeMA) framework. This study is registered with PROSPERO (registration number CRD42022330264).</p><p><strong>Results: </strong>We included 56 studies (7,556 participants). The certainty of the evidence for the primary outcomes, as measured with CINeMA, varied from high to very low (overall; 40 comparisons scored \"very low,\" 7 scored \"low,\" and 814 scored \"high\"). Regarding efficacy, all BZDs, in general, were significantly better than placebo, but there were no significant differences between the different BZDs (high heterogeneity and inconsistency were detected). Regarding treatment discontinuation, with some exceptions, no significant differences were observed in the comparisons against placebo or other BZD (no or low heterogeneity and inconsistency were observed in the different analyses). Regarding treatment tolerability, none of the BZD showed significant differences compared to placebo, except diazepam (RR = 1.61; 95% CI = 1.32; 1.96). Moderate heterogeneity and low inconsistency were observed in the treatment tolerability network meta-analysis.</p><p><strong>Conclusion: </strong>BZDs are overall efficacious for the treatment of GAD and have a favorable safety profile. No distinctive differences were identified when comparing BZD among themselves.</p>","PeriodicalId":20744,"journal":{"name":"Psychotherapy and Psychosomatics","volume":" ","pages":"1-15"},"PeriodicalIF":16.3,"publicationDate":"2025-06-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144369165","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Videoconference-Based Cognitive Behavioral Therapy in Medication-Treated Adults with Attention-Deficit/Hyperactivity Disorder: A Randomized, Assessor-Blinded, Controlled Trial. 基于视频会议的认知行为疗法在药物治疗的成人注意力缺陷/多动障碍:一项随机、评估盲法、对照试验。
IF 16.3 1区 医学
Psychotherapy and Psychosomatics Pub Date : 2025-06-05 DOI: 10.1159/000546539
Aiko Eto, Ayumu Endo, Tokiko Yoshida, Yoichi Seki, Kayoko Taguchi, Minako Hongo, Kohei Takahashi, Yuki Shiko, Yoshiyuki Hirano, Eiji Shimizu
{"title":"Videoconference-Based Cognitive Behavioral Therapy in Medication-Treated Adults with Attention-Deficit/Hyperactivity Disorder: A Randomized, Assessor-Blinded, Controlled Trial.","authors":"Aiko Eto, Ayumu Endo, Tokiko Yoshida, Yoichi Seki, Kayoko Taguchi, Minako Hongo, Kohei Takahashi, Yuki Shiko, Yoshiyuki Hirano, Eiji Shimizu","doi":"10.1159/000546539","DOIUrl":"10.1159/000546539","url":null,"abstract":"<p><strong>Introduction: </strong>Attention-deficit/hyperactivity disorder (ADHD) is a neurodevelopmental disorder that frequently persists into adulthood. Pharmacotherapies are effective but have side effects and dropout risks. Videoconference-based cognitive behavioral therapy (vCBT) has emerged as a promising intervention, particularly for improving treatment accessibility. This study aimed to evaluate the efficacy of vCBT in adults with ADHD compared to treatment-as-usual (TAU) using a randomized, assessor-blinded, controlled trial design.</p><p><strong>Methods: </strong>Thirty participants (aged 18-65 years) with ADHD were randomly assigned to either the 12-session individual vCBT intervention as an adjunct to TAU or TAU group. The primary outcome was the change in the total score on the ADHD Rating Scale-IV (ADHD-RS-IV) with adult prompts by a blinded assessor at 12 weeks from baseline. Secondary outcomes included self-reported measures of ADHD symptoms using the Conners' Adult ADHD Rating-Self-Report, quality of life (QOL) using the Euro QOL 5 Dimension-5 Level, functional impairment using the Sheehan Disability Scale, depression, anxiety, and self-esteem.</p><p><strong>Results: </strong>All of the participants received pharmacotherapy. Participants in the vCBT group (n = 15) demonstrated a significantly greater reduction in ADHD-RS-IV total score than those in the TAU group (vCBT -9.02 vs. TAU 0.84, p = 0.0007, effect size -1.46). Significant improvements in self-reported inattention, hyperactivity, impulsivity, QOL, and work/school performance were observed in favor of vCBT.</p><p><strong>Conclusion: </strong>This study highlights the efficacy of vCBT as a viable and accessible intervention for adults with ADHD, particularly in reducing core symptoms and enhancing QOL and functional outcomes. vCBT is an important alternative treatment, especially for patients who remain symptomatic after pharmacotherapy.</p>","PeriodicalId":20744,"journal":{"name":"Psychotherapy and Psychosomatics","volume":" ","pages":"1-15"},"PeriodicalIF":16.3,"publicationDate":"2025-06-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144234949","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Biofeedback and Training of Interoceptive Insight and Metacognitive Efficacy Beliefs to Improve Adaptive Interoception: A Subclinical Randomised Controlled Trial. 生物反馈和训练内感受洞察力和元认知效能信念(InMe)以改善适应性内感受:一项亚临床随机对照试验。
IF 16.3 1区 医学
Psychotherapy and Psychosomatics Pub Date : 2025-06-05 DOI: 10.1159/000546298
Michal Tanzer, Marina Bobou, Athanasios Koukoutsakis, Alkistis Saramandi, Paul M Jenkinson, Sam Norton, Caroline Selai, Katerina Fotopoulou
{"title":"Biofeedback and Training of Interoceptive Insight and Metacognitive Efficacy Beliefs to Improve Adaptive Interoception: A Subclinical Randomised Controlled Trial.","authors":"Michal Tanzer, Marina Bobou, Athanasios Koukoutsakis, Alkistis Saramandi, Paul M Jenkinson, Sam Norton, Caroline Selai, Katerina Fotopoulou","doi":"10.1159/000546298","DOIUrl":"10.1159/000546298","url":null,"abstract":"<p><strong>Introduction: </strong>Interoception, the sensing, awareness, and regulation of physiological states, is crucial for wellbeing and mental health. Behavioural interventions targeting interoception exist, but randomised controlled trials (RCTs) testing efficacy remain limited. The present, preregistered (ISRCTN16762367) RCT tested the novel Interoceptive iNsight and Metacognitive Efficacy beliefs (InMe) intervention. InMe uses slow breathing and cardiac biofeedback during stress to train interoceptive self-efficacy beliefs and improve self-reported interoception.</p><p><strong>Methods: </strong>Healthy participants aged 18-30 years with low self-reported interoception were randomly assigned (1:1) to the InMe intervention (n = 50) or an active control (guided imagery; n = 52). Participants blinded to allocation were stratified by gender and disordered eating. Assessments included baseline (T0), post-intervention (T1), and 7-8 weeks post-intervention (T2). The primary outcome was the \"adaptive interoception\" factor of the Multidimensional Assessment of Interoceptive Awareness questionnaire.</p><p><strong>Results: </strong>Both arms improved in the primary outcome at T1 (InMe: adjusted M difference = 5.76; 95% CI [-0.03; 11.56], p = 0.05; control: adjusted M difference = 7.90; 95% CI [1.92; 13.87], p = 0.002; marginal R2 = 0.09). However, only InMe sustained this improvement at T2 (InMe: adjusted M difference = 9.25, 95% CI [3.37; 15.13], p < 0.001; control: adjusted M difference = 2.94, 95% CI [-3.07; 8.96], p = 0.72), as indicated by a significant time*arm interaction (b = 6.31; SE = 2.92, 95% CI [0.56; 12.05], p < 0.03; marginal R2 = 0.12). Secondary outcomes showed a reduction in disordered eating scores across both arms at both time points (T1: b = -1.44, SE = 0.37, 95% CI [-2.17; -0.71], p < 0.001; T2: b = -1.05, SE = 0.37, 95% CI [-1.79; -0.32], p = 0.005).</p><p><strong>Conclusion: </strong>The InMe intervention selectively improved self-reported interoception at follow-up but did not outperform the control for secondary outcomes. Future research should explore its efficacy in clinical populations alongside complementary therapies.</p>","PeriodicalId":20744,"journal":{"name":"Psychotherapy and Psychosomatics","volume":" ","pages":"1-23"},"PeriodicalIF":16.3,"publicationDate":"2025-06-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12274049/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144234948","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Evaluation of a Smartphone App Intervention with Telephone Guidance as Transitional Support from Inpatient Treatment to Continuing Care for Individuals with Alcohol Use Disorder: Results from a Randomized Controlled Trial. 智能手机应用程序干预与电话指导作为酒精使用障碍患者从住院治疗到持续护理的过渡支持的评估:来自一项随机对照试验的结果
IF 22.8 1区 医学
Psychotherapy and Psychosomatics Pub Date : 2025-05-23 DOI: 10.1159/000545817
Sebastian Saur,Kiona K Weisel,Catharina Lang,Lukas M Fuhrmann,Niklas Meurer,Daniela Reichl,Mathias Zink,Peter Heepe,Thomas Hillemacher,Wolf-Dietrich Braunwarth,Peter Falkai,Gabriele Koller,Yaroslav Kiderman,Thomas Kraus,Johannes Kornhuber,Philipp Spitzer,Dominikus Bönsch,Mark Stemmler,Anja Hildebrand,Sabine Steins-Loeber,Matthias Berking
{"title":"Evaluation of a Smartphone App Intervention with Telephone Guidance as Transitional Support from Inpatient Treatment to Continuing Care for Individuals with Alcohol Use Disorder: Results from a Randomized Controlled Trial.","authors":"Sebastian Saur,Kiona K Weisel,Catharina Lang,Lukas M Fuhrmann,Niklas Meurer,Daniela Reichl,Mathias Zink,Peter Heepe,Thomas Hillemacher,Wolf-Dietrich Braunwarth,Peter Falkai,Gabriele Koller,Yaroslav Kiderman,Thomas Kraus,Johannes Kornhuber,Philipp Spitzer,Dominikus Bönsch,Mark Stemmler,Anja Hildebrand,Sabine Steins-Loeber,Matthias Berking","doi":"10.1159/000545817","DOIUrl":"https://doi.org/10.1159/000545817","url":null,"abstract":"INTRODUCTIONRelapse rates in individuals with alcohol use disorder (AUD) are particularly high following inpatient treatment. Innovative strategies should specifically target the transitional gap between completion of inpatient treatment and uptake of standard continuing care. This study aimed to determine whether Appstinence, a digital approach that combines a smartphone app intervention with adjunct telephone coaching, more markedly reduces the risk of relapse for 6 months after inpatient AUD treatment in comparison to a control group with access to standard continuing care.METHODSIn this multicenter clinical trial, 356 participants were randomized to the intervention (n=175) or control group (n=181). Eligibility criteria included diagnosis of AUD, smartphone access, no acute suicidality, and no language or neurocognitive impairments. The primary outcome was risk of relapse within six months after randomization, as assessed with the Timeline-Follow-Back method. Secondary outcomes included uptake of standard continuing care, hazardous alcohol consumption, craving, depression and anxiety symptom severity, and well-being.RESULTSThe intervention reduced the risk of relapse within six months as indicated by a log-rank test (HR 0.72, 95% CI 0.53-0.98, p=0.04) and Cox regression adjusted for baseline characteristics (HR 0.67, 95% CI 0.48-0.92, p=0.01). This effect increased when participants fully adhered to the intervention protocol (log-rank test: HR 0.61, 95% CI 0.39-0.94, p=0.02). No significant differences were observed in secondary outcomes.CONCLUSIONOur findings provide supportive evidence for digital AUD transition treatment. Specifically, we found that, in comparison with access standard continuing care, the novel intervention more effectively reduced risk of relapse within six months following inpatient treatment.","PeriodicalId":20744,"journal":{"name":"Psychotherapy and Psychosomatics","volume":"22 1","pages":"1-24"},"PeriodicalIF":22.8,"publicationDate":"2025-05-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144136768","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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