Progress of Theoretical Physics Supplement最新文献

Prostate Cancer Genomics Research Disparities in Africa: Advancing Knowledge in Resource Constrained Settings. 非洲的前列腺癌基因组研究差异：在资源有限的环境中增进知识。

IF 2.5

Progress of Theoretical Physics Supplement Pub Date : 2022-01-01 DOI: 10.1177/10732748221095952

Pedro W Fernandez

{"title":"Prostate Cancer Genomics Research Disparities in Africa: Advancing Knowledge in Resource Constrained Settings.","authors":"Pedro W Fernandez","doi":"10.1177/10732748221095952","DOIUrl":"10.1177/10732748221095952","url":null,"abstract":"Prostate cancer disproportionately affects men of African descent and it is estimated that Africa will bear the highest disease burden in the next decade. Underlying genomic factors may contribute to prostate cancer disparities; however, it is unclear whether Africa has prioritised genomics research toward addressing these disparities. A Pubmed review was performed of publications spanning a 15-year period, with specific focus on prostate cancer genomics research that included samples from Africa and investigators in Africa. Data are presented on research publications from Africa relative to similar publications from different geographical regions, and more specifically, the extent of disparities and the contributions to prostate cancer knowledge as a result of genomics research that included African samples and African institutions. Limited publication output may reflect the infrastructure and funding challenges in Africa. Widespread cooperation should be fostered by sharing capacity and leveraging existing expertise to address the growing cancer burden facing the continent.","PeriodicalId":20614,"journal":{"name":"Progress of Theoretical Physics Supplement","volume":"19 1","pages":"10732748221095952"},"PeriodicalIF":2.5,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9087236/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86923866","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Step Counts on Weekdays, Weekends, and During Physical Education of Navajo High School Students. 纳瓦霍高中学生平日、周末和体育课期间的步数。

IF 3.9

Progress of Theoretical Physics Supplement Pub Date : 2016-10-17 DOI: 10.1007/s40615-016-0294-0

Rachelle Jones, Timothy A Brusseau, Pamela H Kulinna, Hans van der Mars

{"title":"Step Counts on Weekdays, Weekends, and During Physical Education of Navajo High School Students.","authors":"Rachelle Jones, Timothy A Brusseau, Pamela H Kulinna, Hans van der Mars","doi":"10.1007/s40615-016-0294-0","DOIUrl":"10.1007/s40615-016-0294-0","url":null,"abstract":"Background: Understanding the physical activity patterns of youth is important for the implementation and evaluation of programming and interventions designed to change behavior. To date, little is known about the objectively measured physical activity patterns of Native American youth. Therefore, the purpose of the study was to examine the step counts of Navajo youth during weekdays, weekend days, and physical education classes.Methods: Participants included 63 high school students (mean age = 15.14 ± 1.37 years). Youth wore a pedometer (Walk-4-Life 2505) for seven consecutive days. Means and standard deviations were calculated for weekdays, weekend days, and physical education.Results: Boys averaged 11,078 ± 4400 steps/weekday compared to 6493 ± 5651 on weekend days. Girls averaged 7567 ± 5614 on weekdays compared to 7589 ± 7712 on weekend days. Both boys (20 %) and girls (26 %) accumulated a large percentage of their weekday step counts from physical education classes.Conclusions: Findings highlight the importance of additional physical activity opportunities in the community. Youth are falling well short of recommended levels of physical activity with physical education being an important source of physical activity.","PeriodicalId":20614,"journal":{"name":"Progress of Theoretical Physics Supplement","volume":"138 1","pages":"None"},"PeriodicalIF":3.9,"publicationDate":"2016-10-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86824268","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Cholesteryl esters stabilize human CD1c conformations for recognition by self-reactive T cells. 胆固醇酯能稳定人类 CD1c 的构象，使其能被自我反应 T 细胞识别。

Progress of Theoretical Physics Supplement Pub Date : 2016-03-01 Epub Date: 2016-02-16 DOI: 10.1073/pnas.1519246113

Salah Mansour, Anna S Tocheva, Chris Cave-Ayland, Moritz M Machelett, Barbara Sander, Nikolai M Lissin, Peter E Molloy, Mark S Baird, Gunthard Stübs, Nicolas W J Schröder, Ralf R Schumann, Jörg Rademann, Anthony D Postle, Bent K Jakobsen, Ben G Marshall, Rajendra Gosain, Paul T Elkington, Tim Elliott, Chris-Kriton Skylaris, Jonathan W Essex, Ivo Tews, Stephan D Gadola

{"title":"Cholesteryl esters stabilize human CD1c conformations for recognition by self-reactive T cells.","authors":"Salah Mansour, Anna S Tocheva, Chris Cave-Ayland, Moritz M Machelett, Barbara Sander, Nikolai M Lissin, Peter E Molloy, Mark S Baird, Gunthard Stübs, Nicolas W J Schröder, Ralf R Schumann, Jörg Rademann, Anthony D Postle, Bent K Jakobsen, Ben G Marshall, Rajendra Gosain, Paul T Elkington, Tim Elliott, Chris-Kriton Skylaris, Jonathan W Essex, Ivo Tews, Stephan D Gadola","doi":"10.1073/pnas.1519246113","DOIUrl":"10.1073/pnas.1519246113","url":null,"abstract":"Cluster of differentiation 1c (CD1c)-dependent self-reactive T cells are abundant in human blood, but self-antigens presented by CD1c to the T-cell receptors of these cells are poorly understood. Here we present a crystal structure of CD1c determined at 2.4 Å revealing an extended ligand binding potential of the antigen groove and a substantially different conformation compared with known CD1c structures. Computational simulations exploring different occupancy states of the groove reenacted these different CD1c conformations and suggested cholesteryl esters (CE) and acylated steryl glycosides (ASG) as new ligand classes for CD1c. Confirming this, we show that binding of CE and ASG to CD1c enables the binding of human CD1c self-reactive T-cell receptors. Hence, human CD1c adopts different conformations dependent on ligand occupancy of its groove, with CE and ASG stabilizing CD1c conformations that provide a footprint for binding of CD1c self-reactive T-cell receptors. ","PeriodicalId":20614,"journal":{"name":"Progress of Theoretical Physics Supplement","volume":"1 1","pages":"E1266-75"},"PeriodicalIF":0.0,"publicationDate":"2016-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4780616/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86981224","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Stability of Instability of Plane-Wave Hartree-Fock Solutions and the Helical Spin Arrangement 平面波Hartree-Fock解的不稳定性及螺旋自旋排列

Progress of Theoretical Physics Supplement Pub Date : 2013-08-02 DOI: 10.1143/PTPS.E65.492

N. Fukuda, T. Ogawa, T. Soda

引用次数: 0

A Relation between the Minkowski and Isobaric Spaces 闵可夫斯基空间与等压空间的关系

Progress of Theoretical Physics Supplement Pub Date : 2013-08-02 DOI: 10.1143/PTPS.E65.542

T. Toyoda

引用次数: 0

Higher Symmetry Groups with Parity Mixing 具有宇称混合的高对称群

Progress of Theoretical Physics Supplement Pub Date : 2013-08-02 DOI: 10.1143/PTPS.E65.56

R. Marshak, S. Okubo, J. Schechter, J. Wojtaszek

引用次数: 0

The Rearrangement of Symmetries in Dynamical Maps 动态映射中对称性的重排

Progress of Theoretical Physics Supplement Pub Date : 2013-08-02 DOI: 10.1143/PTPS.E65.637

L. Leplae, R. Sen, H. Umezawa

引用次数: 3

Possible G-Parity Nonconservation in Muon Capture Reactions : Angular Distribution of Recoils 介子俘获反应中可能的g宇称不守恒:反冲的角分布

Progress of Theoretical Physics Supplement Pub Date : 2013-08-02 DOI: 10.1143/PTPS.E65.96

M. Morita, R. Morita, T. Shirafuji

引用次数: 0

Nuclear Force and the Bethe-Salpeter Equation 核力和贝特-萨尔皮特方程

Progress of Theoretical Physics Supplement Pub Date : 2013-08-02 DOI: 10.1143/PTPS.E65.76

M. Kawaguchi

引用次数: 0

Dynamical Interpretation of Spurions spurons的动力学解释

Progress of Theoretical Physics Supplement Pub Date : 2013-08-02 DOI: 10.1143/PTPS.E65.207

K. Nishijima, M. Saffouri

引用次数: 0