Vascular Diseases and Therapeutics最新文献_第2页

Influence of internal medicine perioperative consult team on vascular surgical patients 内科围手术期会诊团队对血管外科患者的影响

Vascular Diseases and Therapeutics Pub Date : 1900-01-01 DOI: 10.15761/vdt.1000188

A. Cherukupalli, S. Parmar, Yuda Shih, A. Butt, Gary K.Yang, Jonathan D. Misskey, York N. Hsiang

引用次数: 0

Echocardiography and cardiac embolic stroke 超声心动图和心脏栓塞性中风

Vascular Diseases and Therapeutics Pub Date : 1900-01-01 DOI: 10.15761/vdt.1000180

Nguyen Tuan Vu, Le Huu Quynh Trang

引用次数: 0

Clinical and radiological pitfalls in Isolated cortical venous thrombosis. Don’t miss the “last slice” 孤立性皮质静脉血栓形成的临床和影像学缺陷。不要错过“最后一片”

Vascular Diseases and Therapeutics Pub Date : 1900-01-01 DOI: 10.15761/vdt.1000168

M. Boukobza, Edmond Doggo, É. Manchon, J. Laissy

引用次数: 0

A case of endovascular treatment for juxtarenal aortic calcified occlusion with intermittent claudication 血管内治疗肾旁主动脉钙化闭塞伴间歇性跛行1例

Vascular Diseases and Therapeutics Pub Date : 1900-01-01 DOI: 10.15761/VDT.1000173

Keisuke Ueno, Y. Shinoda, I. Shiojima, S. Hoshida

{"title":"A case of endovascular treatment for juxtarenal aortic calcified occlusion with intermittent claudication","authors":"Keisuke Ueno, Y. Shinoda, I. Shiojima, S. Hoshida","doi":"10.15761/VDT.1000173","DOIUrl":"https://doi.org/10.15761/VDT.1000173","url":null,"abstract":"We focused on the importance of procedure strategy for the planning of treatment in a patient with calcified occlusive abdominal aorta with bilateral renal artery stenosis showing intermittent claudication. A 76-year-old man was admitted to our hospital with acute decompensated heart failure. He had a history of hypertension, dyslipidaemia, chronic kidney disease, smoking habit, heavy alcohol intake, and coronary artery bypass graft surgery 6 years ago. Examination revealed that the abdominal aorta was nearly completely occluded due to a large calcified nodule involving bilateral renal arteries. Because he suffered from bilateral intermittent claudication, we decided to undertake revascularization of the abdominal aorta and left renal artery by endovascular treatment (EVT) in a single session. We aimed to secure disappearance of the pressure gradient, but not full distension of the abdominal aorta. We undertook EVT with balloon-expandable stent in order to maintain superior mesenteric artery flow and to ensure firm dilation of the left renal artery. For the calcified abdominal aorta, we tried to construct bidirectional routes of abdominal aortic blood flow antegradely and retrogradely. Our technique is less invasive than bypass surgery and can be performed safely under local anaesthesia using percutaneous access.","PeriodicalId":206117,"journal":{"name":"Vascular Diseases and Therapeutics","volume":"32 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129654737","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Effect of Menaquinone-7 (vitamin K2) on vascular elasticity in healthy subjects: results from a one-year study 甲萘醌-7(维生素K2)对健康受试者血管弹性的影响:为期一年的研究结果

Vascular Diseases and Therapeutics Pub Date : 1900-01-01 DOI: 10.15761/VDT.1000179

C. Vermeer, H. Vik

{"title":"Effect of Menaquinone-7 (vitamin K2) on vascular elasticity in healthy subjects: results from a one-year study","authors":"C. Vermeer, H. Vik","doi":"10.15761/VDT.1000179","DOIUrl":"https://doi.org/10.15761/VDT.1000179","url":null,"abstract":"Background: Matrix Gla-Protein (MGP) is involved in the prevention of arterial calcification. During vitamin K-insufficiency, MGP is produced in its inactive form: dp-ucMGP. Two 3-year intervention studies in the general population have shown that increased vitamin K intake may decrease arterial stiffening, but the difference with placebo became only significant in the third year of treatment. In the present trial we have investigated whether in a pre-selected group of vitamin K-insufficient subjects (men and women) an effect of vitamin K-supplementation may be demonstrated within one year. Methods: A randomized placebo-controlled clinical trial was performed in 243 subjects (40-70 years old) characterized by circulating dp-ucMGP concentrations above the median of the general population. Arterial stiffness was concluded from the carotid-femoral pulse-wave velocity (cfPWV), and other vascular characteristics were measured by echotracking of the common carotid artery. Treatment was performed with either vitamin K (menaquinone-7, MK-7) or placebo for one year. Results: In the total study group, MK-7 induced a significant decrease of both dp-ucMGP and cfPWV. After subdividing by gender, it appeared that the effects were only seen in women, in whom we also found beneficial effects in other vascular characteristics as well as in body weight and BMI. Conclusions : High vitamin K intake decreased age-related vascular stiffening. The effects were most obvious in women with poor vitamin K status and were statistically significant after one year of treatment. In-tima-Media Young’s Modulus","PeriodicalId":206117,"journal":{"name":"Vascular Diseases and Therapeutics","volume":"5 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124817466","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 7

Immediate benefit of balloon aortic valvuloplasty in severe aortic stenosis: hemodynamic echographic assessment in Intensive Coronary Care Unit 主动脉瓣球囊成形术治疗严重主动脉瓣狭窄的直接益处:冠状动脉重症监护病房的血流动力学超声评估

Vascular Diseases and Therapeutics Pub Date : 1900-01-01 DOI: 10.15761/vdt.1000154

M. Calcaianu, U. Crimizade, N. Messas, D. Bresson, J. Wiedemann, O. Roth, M. Kindo, O. Morel, J. Lévy, L. Jacquemin, P. Ohlmann

{"title":"Immediate benefit of balloon aortic valvuloplasty in severe aortic stenosis: hemodynamic echographic assessment in Intensive Coronary Care Unit","authors":"M. Calcaianu, U. Crimizade, N. Messas, D. Bresson, J. Wiedemann, O. Roth, M. Kindo, O. Morel, J. Lévy, L. Jacquemin, P. Ohlmann","doi":"10.15761/vdt.1000154","DOIUrl":"https://doi.org/10.15761/vdt.1000154","url":null,"abstract":"Background : Balloon aortic valvuloplasty (BAV) might be a life saving procedure in critically advanced aortic stenosis (AS) as a bridge therapy to surgical aortic valve replacement (AVR) or to trans-catheter aortic heart valve (TAVI), by reducing trans-aortic gradient and increasing aortic valve area (AVA). Few is known on the benefit of BAV on cardiac output. Our study proposed to evaluate the hemodynamic changes after BAV by transthoracic echocardiography (TTE). Methods: 30 consecutive patients with AS undergoing BAV were prospectively included between July 2014 and July 2015. Hemodynamic assessment was performed pre- and post-BAV by TTE. Low cardiac output (CO) was defined by a cardiac index (CI) < 2.5 L/min/m 2 . Results: Mean age was 82 ± 8 years; 56.7% were female; mean logistic EuroSCORE I was 31 ± 19 %. 20 patients (67%) had low CO. TTE showed that the patients with low CO improved AVA (from 0.57 ± 0.2 to 1.05 ± 0.5, p=0.043), CI (from 1.9 ± 0.4 to 2.8 ± 1.0 L/min/m 2 , p<0.0001), LVEF (from 31 ± 16 to 38 ± 13%, p=0.006), tend to decrease systolic pulmonary artery pressure (sPAP) (from 52 ± 19 to 43 ± 11 mmHg, p=0.06) and to increase mean arterial pressure (MAP) (from 79 ± 10 to 83 ± 12 mmHg, p=0.046). There was no statistically significant difference in terms of hemodynamic in patients with a normal CO (CI ≥ 2.5 L/min/m 2 ). Conclusion: By increasing AVA, BAV significantly and immediately improve cardiac output especially in patients with low CO at baseline.","PeriodicalId":206117,"journal":{"name":"Vascular Diseases and Therapeutics","volume":"9 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122022566","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A modulator peptide stabilize the eNOS protein similar to atorvastatin in atherosclerosis patients 一种类似于阿托伐他汀的调节肽稳定动脉粥样硬化患者的eNOS蛋白

Vascular Diseases and Therapeutics Pub Date : 1900-01-01 DOI: 10.15761/vdt.1000166

K. S. Freitas e Silva

{"title":"A modulator peptide stabilize the eNOS protein similar to atorvastatin in atherosclerosis patients","authors":"K. S. Freitas e Silva","doi":"10.15761/vdt.1000166","DOIUrl":"https://doi.org/10.15761/vdt.1000166","url":null,"abstract":"Atherosclerosis is a cardiovascular disease marked by chronic inflammation. The disease is intimately related to the accumulation of fatty acids in the tunica intima of medium and large caliber arteries. The development of the disease respond to alteration of the vascular and immune system homeostasis. The inflammatory process is aggravated by the action of immune cells. The diagnosis of the disease is invasive in most cases. Thus, new diagnostic and therapeutic techniques are required and could increase the quality of life of atherosclerotic patients. The eNOS gene has been indicated as an efficient biomarker of cardiovascular diseases, including atherosclerosis, stroke and myocardium infarction. The eNOS gene and the protein it encodes control the production of nitric oxide. This compound takes part in a large variety of biological functions and its action is crucial for the protection of arteries against damage. Here, an in-silico approach was used to design two small active peptides as a way to stabilize eNOS and guarantee its normal level of function regarding the production of nitric oxide. We hypothesize that the use of designed peptide would lead to an efficient therapy and with less or none side effect to atherosclerotic patients, as a substitution of statins therapy, such as atorvastatin. For future perspective, an assay of the modulating peptides is being designed to be tested in vitro and in vivo in order to be possibly used as a new therapeutic agent.","PeriodicalId":206117,"journal":{"name":"Vascular Diseases and Therapeutics","volume":"71 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125622070","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Case report for chronic thromboembolic pulmonary hypertension (CTEPH) caused by deep vein thrombosis due to uterine myoma 子宫肌瘤所致深静脉血栓形成所致慢性血栓栓塞性肺动脉高压1例

Vascular Diseases and Therapeutics Pub Date : 1900-01-01 DOI: 10.15761/VDT.1000185

Hyun Jin Kim, H. Shin

引用次数: 0

The PERTINI Method: A simple technique for re-sheathing a physician-modified endograft PERTINI法:一种简单的医师改良内移植物再鞘技术

Vascular Diseases and Therapeutics Pub Date : 1900-01-01 DOI: 10.15761/vdt.1000193

F. De Santis

引用次数: 0

Trigeminal Neuralgia: The pain is a given, the cause is not 三叉神经痛:疼痛是给定的，原因不是

Vascular Diseases and Therapeutics Pub Date : 1900-01-01 DOI: 10.15761/VDT.1000175

S. Vassilopoulou, A. Tountopoulou, E. Korompoki, L. Poulou, Christos Gkogkas

引用次数: 0