PROCEEDINGS OF THE INTERNATIONAL CONFERENCE OF COMPUTATIONAL METHODS IN SCIENCES AND ENGINEERING 2019 (ICCMSE-2019)最新文献

{"title":"Survival analysis of Portuguese SMEs: A preliminary approach","authors":"Ana Borges, M. Machado, F. Duarte","doi":"10.1063/1.5137998","DOIUrl":"https://doi.org/10.1063/1.5137998","url":null,"abstract":"A high rate of corporate bankruptcy can be devastating to economic and entrepreneurial ecosystem, especially among countries with a high concentration of Micro, Small and Medium Sized Enterprises (SMEs). Most bankruptcy studies focus on large companies, ignoring the fact that SMEs play a key role in achieving the objectives of job creation and economic growth, which are particularly relevant in the peripheral countries of the European Union. Considering the relevance of these companies to the Portuguese economy and the scarcity of empirical studies, in this paper we offer a preliminary study about the determinants of survival of SMEs operating in Portugal. Unlike to the traditional models (i.e., static models tending to ignore the longitudinal factor of time to predict corporate bankruptcy) this study applies the Cox proportional risk model in order to predict, based on historical data taken from SABI, the probability whether a SME will be in financial distress. Using data between 2008-18 and controlling for spatial effect (Region), Size and Activity Sector, we found evidences on the negative relation between ownership concentration and financial distress.","PeriodicalId":20565,"journal":{"name":"PROCEEDINGS OF THE INTERNATIONAL CONFERENCE OF COMPUTATIONAL METHODS IN SCIENCES AND ENGINEERING 2019 (ICCMSE-2019)","volume":"5 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-12-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75244414","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Molecular dynamics simulation of myopathy-related mutant FHL1 in water and analysis of structure stabilization","authors":"H. Takeuchi, H. Okajima, H. Itoga, K. Nobuoka, Hironao Yamada, T. Miyakawa, R. Morikawa, Y. Hayashi, M. Takasu","doi":"10.1063/1.5137923","DOIUrl":"https://doi.org/10.1063/1.5137923","url":null,"abstract":"Mutations in the FHL1 gene can cause X-linked hereditary myopathy, which causes one of the rarest intractable diseases. The age of the disease onset is quite variable from early infancy to adulthood, and the patients show progressive muscle weakness and atrophy. The FHL1 protein is constituted by four and a half LIM domains. Each LIM domain contains two zinc fingers, which contribute to the structural stability of the LIM domain. A change in the cysteine or histidine residues in the 2nd LIM domain (LIM2) is closely associated with the disease severity. Therefore, LIM2 is suggested to have an essential role in maintaining the structure of FHL1. In this study, molecular dynamics simulation was performed on molecular models consisting of LIM1 and LIM2 of wild and mutant FHL1. We calculated the extent of distortion of zinc finger structure and measured the distance between zinc atom and Cα atom of zinc-coordinated residues. Our analysis showed that the correlation between these two quantities is larger in the mutants associated with severe myopathy.Mutations in the FHL1 gene can cause X-linked hereditary myopathy, which causes one of the rarest intractable diseases. The age of the disease onset is quite variable from early infancy to adulthood, and the patients show progressive muscle weakness and atrophy. The FHL1 protein is constituted by four and a half LIM domains. Each LIM domain contains two zinc fingers, which contribute to the structural stability of the LIM domain. A change in the cysteine or histidine residues in the 2nd LIM domain (LIM2) is closely associated with the disease severity. Therefore, LIM2 is suggested to have an essential role in maintaining the structure of FHL1. In this study, molecular dynamics simulation was performed on molecular models consisting of LIM1 and LIM2 of wild and mutant FHL1. We calculated the extent of distortion of zinc finger structure and measured the distance between zinc atom and Cα atom of zinc-coordinated residues. Our analysis showed that the correlation between these two quantities is larger in the...","PeriodicalId":20565,"journal":{"name":"PROCEEDINGS OF THE INTERNATIONAL CONFERENCE OF COMPUTATIONAL METHODS IN SCIENCES AND ENGINEERING 2019 (ICCMSE-2019)","volume":"24 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-12-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74224696","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Piecewise constant control approximations in the problem on effective resource consumption","authors":"A. Tarasyev, A. Usova","doi":"10.1063/1.5137942","DOIUrl":"https://doi.org/10.1063/1.5137942","url":null,"abstract":"","PeriodicalId":20565,"journal":{"name":"PROCEEDINGS OF THE INTERNATIONAL CONFERENCE OF COMPUTATIONAL METHODS IN SCIENCES AND ENGINEERING 2019 (ICCMSE-2019)","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-12-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85840183","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Parametric analysis on the seismic response of masonry bell towers","authors":"A. Formisano, F. Fabbrocino, G. Vaiano","doi":"10.1063/1.5138008","DOIUrl":"https://doi.org/10.1063/1.5138008","url":null,"abstract":"The Italy is a country rich of historical buildings, often made up of bricks, which were seriously damaged or suffered collapse after recent devastating earthquakes. In this framework the current work shows the results of instrumental researches and structural analysis aiming at the description of the seismic behaviour of masonry belfries or bell towers. Forty case studies belonging to thirteen Italian regions, so to be representative of the different seismic areas of the country, have been herein examined. A global modelling approach based on macro-elements models able to reproduce the seismic behaviour of bell towers with the support of the equivalent frame technique has been implemented through the 3MURI software. This numerical approach has allowed to reproduce the sequence of the main damage mechanisms of structures as horizontal forces increase. Therefore, a parametric analysis has been performed to evaluate the seismic response of investigated structures by changing their geometrical parameters. From the achieved results the individuation of the bell towers most at risk placed in different parts of Italy (North, Centre and South) has been faced. Finally, a new third order polynomial formula is proposed to calculate the principal vibration period of light squared stone towers as a function of their slenderness.The Italy is a country rich of historical buildings, often made up of bricks, which were seriously damaged or suffered collapse after recent devastating earthquakes. In this framework the current work shows the results of instrumental researches and structural analysis aiming at the description of the seismic behaviour of masonry belfries or bell towers. Forty case studies belonging to thirteen Italian regions, so to be representative of the different seismic areas of the country, have been herein examined. A global modelling approach based on macro-elements models able to reproduce the seismic behaviour of bell towers with the support of the equivalent frame technique has been implemented through the 3MURI software. This numerical approach has allowed to reproduce the sequence of the main damage mechanisms of structures as horizontal forces increase. Therefore, a parametric analysis has been performed to evaluate the seismic response of investigated structures by changing their geometrical parameters. Fr...","PeriodicalId":20565,"journal":{"name":"PROCEEDINGS OF THE INTERNATIONAL CONFERENCE OF COMPUTATIONAL METHODS IN SCIENCES AND ENGINEERING 2019 (ICCMSE-2019)","volume":"62 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-12-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"91084789","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Kinetics of hemolysis induced by thioridazine","authors":"Bilyana Tacheva, B. Paarvanova, Stanislav Bozhikov, I. Ivanov, M. Karabaliev","doi":"10.1063/1.5138026","DOIUrl":"https://doi.org/10.1063/1.5138026","url":null,"abstract":"The process of hemolysis of erythrocyte suspension induced by thioridazine (TDZ) was investigated by measuring the UV-Vis absorbance spectrum in the range 200 nm - 700 nm. The time needed to obtain the spectrum in this range was 12.5 s, so the spectrum was measured each 15 s. This permitted to follow the changes in absorbance at different wavelengths of the spectra during hemolysis. It was found that at most of the wavelengths measured the absorbance decreased which was related to the decrease of the light-scattering by the intact erythrocytes. In contrast, the absorbance peak of the hemoglobin (Hb) at 416 nm increased significantly during hemolysis. This was attributed to smaller light absorption by Hb when the erythrocytes were still intact and the Hb is still inside the erythrocytes. This phenomenon was due to the forward-scattered light that did not penetrate the erythrocytes and did not interact with Hb. When Hb was released from erythrocytes it could already interact with the light, resulting in increase of the absorption peaks of Hb and especially of the peak at 416 nm. The kinetics of the decrease of light-scattering at 700 nm and 500 nm and the increase of Hb absorption at 416 nm were compared and it was found that they are directly related. The kinetics of hemolysis induced by different concentrations of TDZ were measured. It was found that the time for hemolysis depended on the TDZ concentration as power function with power factor of minus 5.The process of hemolysis of erythrocyte suspension induced by thioridazine (TDZ) was investigated by measuring the UV-Vis absorbance spectrum in the range 200 nm - 700 nm. The time needed to obtain the spectrum in this range was 12.5 s, so the spectrum was measured each 15 s. This permitted to follow the changes in absorbance at different wavelengths of the spectra during hemolysis. It was found that at most of the wavelengths measured the absorbance decreased which was related to the decrease of the light-scattering by the intact erythrocytes. In contrast, the absorbance peak of the hemoglobin (Hb) at 416 nm increased significantly during hemolysis. This was attributed to smaller light absorption by Hb when the erythrocytes were still intact and the Hb is still inside the erythrocytes. This phenomenon was due to the forward-scattered light that did not penetrate the erythrocytes and did not interact with Hb. When Hb was released from erythrocytes it could already interact with the light, resulting in inc...","PeriodicalId":20565,"journal":{"name":"PROCEEDINGS OF THE INTERNATIONAL CONFERENCE OF COMPUTATIONAL METHODS IN SCIENCES AND ENGINEERING 2019 (ICCMSE-2019)","volume":"16 4 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-12-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"91265777","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Proton conducting mechanism in perovskite metal oxides from viewpoints of local structural relaxation and local chemical bonding change","authors":"T. Onishi","doi":"10.1063/1.5137913","DOIUrl":"https://doi.org/10.1063/1.5137913","url":null,"abstract":"From our previous molecular orbital calculations using hybrid density functional theory for proton-conducting perovskite metal oxides, it was found that proton pumping effect is combined during proton-conduction, and covalent bonding change occurs in a diagonal line. It is known that pure perovskite metal oxides are regarded as boundary system. It is because they consist of the same unit structures. However, during proton-conduction, both local structural relaxation and local chemical bonding change must be taken into consideration. In this paper, the proton-conducting mechanism is explained from the different viewpoints of local structural relaxation and local chemical bonding change.From our previous molecular orbital calculations using hybrid density functional theory for proton-conducting perovskite metal oxides, it was found that proton pumping effect is combined during proton-conduction, and covalent bonding change occurs in a diagonal line. It is known that pure perovskite metal oxides are regarded as boundary system. It is because they consist of the same unit structures. However, during proton-conduction, both local structural relaxation and local chemical bonding change must be taken into consideration. In this paper, the proton-conducting mechanism is explained from the different viewpoints of local structural relaxation and local chemical bonding change.","PeriodicalId":20565,"journal":{"name":"PROCEEDINGS OF THE INTERNATIONAL CONFERENCE OF COMPUTATIONAL METHODS IN SCIENCES AND ENGINEERING 2019 (ICCMSE-2019)","volume":"45 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-12-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75572851","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A statistical contribution on the film tourism. A case study","authors":"H. Sol, L. Grilo, J. P. Coelho","doi":"10.1063/1.5138002","DOIUrl":"https://doi.org/10.1063/1.5138002","url":null,"abstract":"The evaluation of the impact that the images perceived by the spectators have in the destination choices they make as tourists is a growing research field, not only in Tourism and Marketing Management but also among the Behavioural Sciences. Based on a questionnaire previously developed on a Film Tourism sub-project, with qualitative variables in nominal and ordinal scale, a survey was conducted during a number of film screenings hosted by Tomar’s (a medium-sized city in Portugal) Film Society. After the characterization of the random sample with the sociodemographic variables, the nonparametric test Pearson chi-square was applied to test the null hypothesis of independence between the variable “Gender” and the variables “Have you ever visited a place by influence of a film?” or “Destination-dream by strong influence of a film”. Given that the null hypothesis is not rejected, there is no statistical evidence to consider a dependence/relationship between these variables. Other finding is statistically significant Spearman correlations between some variables, such as “Education level” and “The average number of activities of Film Tourism”.The evaluation of the impact that the images perceived by the spectators have in the destination choices they make as tourists is a growing research field, not only in Tourism and Marketing Management but also among the Behavioural Sciences. Based on a questionnaire previously developed on a Film Tourism sub-project, with qualitative variables in nominal and ordinal scale, a survey was conducted during a number of film screenings hosted by Tomar’s (a medium-sized city in Portugal) Film Society. After the characterization of the random sample with the sociodemographic variables, the nonparametric test Pearson chi-square was applied to test the null hypothesis of independence between the variable “Gender” and the variables “Have you ever visited a place by influence of a film?” or “Destination-dream by strong influence of a film”. Given that the null hypothesis is not rejected, there is no statistical evidence to consider a dependence/relationship between these variables. Other finding is statistically sign...","PeriodicalId":20565,"journal":{"name":"PROCEEDINGS OF THE INTERNATIONAL CONFERENCE OF COMPUTATIONAL METHODS IN SCIENCES AND ENGINEERING 2019 (ICCMSE-2019)","volume":"20 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-12-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83573482","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Contribution to individualized environmental education","authors":"Aspasia Karagiannopoulou, F. Batzias, O. Kopsidas","doi":"10.1063/1.5138111","DOIUrl":"https://doi.org/10.1063/1.5138111","url":null,"abstract":"In this work, we modify the Holland’ s methodology for the categorization of human personalities by including queries (in the corresponding questionnaire that serves as an evaluation tool) investigating its responders attitude as regards his/her willingness to be professionally engaged with the natural or/and anthropogenic environment. The population used as representative sample consisted of 250 students following courses at high school and university level. The quantitative methods used were descriptive statistics, parametric and non-parametric statistics hypothesis (on causal relations) testing, categorical semantics, ontological mapping fuzzy sets and interval algebra. The results obtained showed relative significant internal consistency at macro-level for almost half of the interviewees, but the dependence of answers to environmental queries on the rest responds to the rest queries was insignificant, indicating lack of specific knowledge and clarification of the corresponding concepts at micro-level.In this work, we modify the Holland’ s methodology for the categorization of human personalities by including queries (in the corresponding questionnaire that serves as an evaluation tool) investigating its responders attitude as regards his/her willingness to be professionally engaged with the natural or/and anthropogenic environment. The population used as representative sample consisted of 250 students following courses at high school and university level. The quantitative methods used were descriptive statistics, parametric and non-parametric statistics hypothesis (on causal relations) testing, categorical semantics, ontological mapping fuzzy sets and interval algebra. The results obtained showed relative significant internal consistency at macro-level for almost half of the interviewees, but the dependence of answers to environmental queries on the rest responds to the rest queries was insignificant, indicating lack of specific knowledge and clarification of the corresponding concepts at micro-level.","PeriodicalId":20565,"journal":{"name":"PROCEEDINGS OF THE INTERNATIONAL CONFERENCE OF COMPUTATIONAL METHODS IN SCIENCES AND ENGINEERING 2019 (ICCMSE-2019)","volume":"80 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-12-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76199253","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Preface of the Session: ‘Allometry and Scaling in Medicine, Biophysics and Ecology’","authors":"A. Atanasov","doi":"10.1063/1.5138020","DOIUrl":"https://doi.org/10.1063/1.5138020","url":null,"abstract":"","PeriodicalId":20565,"journal":{"name":"PROCEEDINGS OF THE INTERNATIONAL CONFERENCE OF COMPUTATIONAL METHODS IN SCIENCES AND ENGINEERING 2019 (ICCMSE-2019)","volume":"8 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-12-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76321990","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The numerical studies of the multi-stage damage behavior of an explosively-driven HR2 cylinder","authors":"Jia Yuxi, Jian Songqing, L. Wentao, Xiong Jun","doi":"10.1063/1.5138083","DOIUrl":"https://doi.org/10.1063/1.5138083","url":null,"abstract":"The damage in the metallic thick-walled cylinder expanded by explosive load is highly complicated and is particularly important to the design of munitions and armaments. A serial of experiments with different strain rate in steel have been done to explore the fracture behavior in the metallic cylinder [1] ∼ [8]. Figure 1 shows the sketch of the experimental specimen and the field [8]. The experimental results in the Fig. 2 revealed that the shear fracture was dominant while the cylinder deformed at a high strain rate [1], [3]. As the Fig.3, the recovered fragments showed the damage in the cylinder contained many fracture mechanisms such as spallation, tensional fraction and adiabatic shear band [3].The damage in the metallic thick-walled cylinder expanded by explosive load is highly complicated and is particularly important to the design of munitions and armaments. A serial of experiments with different strain rate in steel have been done to explore the fracture behavior in the metallic cylinder [1] ∼ [8]. Figure 1 shows the sketch of the experimental specimen and the field [8]. The experimental results in the Fig. 2 revealed that the shear fracture was dominant while the cylinder deformed at a high strain rate [1], [3]. As the Fig.3, the recovered fragments showed the damage in the cylinder contained many fracture mechanisms such as spallation, tensional fraction and adiabatic shear band [3].","PeriodicalId":20565,"journal":{"name":"PROCEEDINGS OF THE INTERNATIONAL CONFERENCE OF COMPUTATIONAL METHODS IN SCIENCES AND ENGINEERING 2019 (ICCMSE-2019)","volume":"17 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-12-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79891747","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}