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[The inhalational toxicity of the antibiotic preparation Bactericin for plant protection]. [植物保护用抗生素制剂Bactericin的吸入毒性研究]。
Problemi na khigienata Pub Date : 1993-01-01
Zh Khalkova, Kh Zaĭtsov
{"title":"[The inhalational toxicity of the antibiotic preparation Bactericin for plant protection].","authors":"Zh Khalkova,&nbsp;Kh Zaĭtsov","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The acute and subacute inhalation toxicity of a new Bulgarian antibiotic preparation \"Bactericin\" for plant protection is examined. It is meant for the treatment of seeds from tomatoes before sowing. The inhalational toxicity is evaluated by a complex of toxicometric, integral, behavioural, clinic-laboratory, biochemical and histological methods. The maximum concentration reached by dispersing is 40 mg.m-3. In the condition of acute (unrepeated exposure) and subacute (60 exposure) the concentration of 40 mg.m-3 causes no lethality, symptoms of intoxication and toxic effects in the organism of white rats therefore it could be accepted as not operative. The preparation conceals no danger of acute and chronic inhalational poisonings when working with the latter. On the basis of the performed investigations and bearing in mind, that the preparation is in the group of the antibiotics, a proposal is made for the purpose of orientation MAG in the air of the working zone -0.5 mg.m-3.</p>","PeriodicalId":20520,"journal":{"name":"Problemi na khigienata","volume":"18 ","pages":"105-14"},"PeriodicalIF":0.0,"publicationDate":"1993-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18843937","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[The health and demographic criteria in the assessment of and the approach to resolving the ecological problem in Bulgaria]. [保加利亚评估生态问题的健康和人口标准及解决生态问题的办法]。
Problemi na khigienata Pub Date : 1993-01-01
M Chuchkova
{"title":"[The health and demographic criteria in the assessment of and the approach to resolving the ecological problem in Bulgaria].","authors":"M Chuchkova","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The health and demographic aspects of the ecological problem are treated in scientific and theoretical plan. Data, illustrating the unfavourable changes in the health and demographic situation of the country, are given. They are interpreted as a result of the ecological stress and the existing crisis situation. The indices \"local demographic potential\" (LDP), \"local health potential\" (LHP) and \"territorial health index\" (THI) have the meaning of integral criteria for the urbanized environmental quality. They are elaborated on the basis of complete characteristics on the demographic process (birth-rate, mortality, infant mortality and natural growth) and all basic groups of diseases and nosological units, traced from 1980 up to now. Since 1986 an extremely dangerous tendency of rapid and socially significant deterioration of the health of the population has been observed. This country is in the process of depopulation from 1990. The data from the investigation confirm the priority significance of the activities concerning the protection and steadfast development of the environment with the principle objective--prevention and consolidation of the health of the population.</p>","PeriodicalId":20520,"journal":{"name":"Problemi na khigienata","volume":"18 ","pages":"3-10"},"PeriodicalIF":0.0,"publicationDate":"1993-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18844435","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[The direct health effects of air pollution in Vratsa in 1991]. [1991年Vratsa空气污染对健康的直接影响]。
Problemi na khigienata Pub Date : 1993-01-01
S Tabakova, Ts Koleva, P Petrov, G Simeonov
{"title":"[The direct health effects of air pollution in Vratsa in 1991].","authors":"S Tabakova,&nbsp;Ts Koleva,&nbsp;P Petrov,&nbsp;G Simeonov","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The effect of air pollution in the town of Vratsa on the daily morbidity of the population has been studied during the first half of 1991. Studies are performed on the correlation between the daily dynamics in the pollution according to specific for the town indices ammonia, hydrogen sulfide, sulphur dioxide, nitric oxides, dust, meteorological parameters temperature of the air, relative humidity, air velocity, barometric pressure and some respiratory and allergic diseases among the population. It is already established that the level of the air pollution in the town of Vratsa, among which dominate ammonia and hydrogen sulfide, have a direct effect on the acute respiratory morbidity, more expressed among the children. This influence is traced both in episodes of increased pollution, and in the course of several days afterwards and is conductive by the combination of unfavourable meteorological conditions, hindering the dispersion of the atmospheric pollutants.</p>","PeriodicalId":20520,"journal":{"name":"Problemi na khigienata","volume":"18 ","pages":"32-44"},"PeriodicalIF":0.0,"publicationDate":"1993-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18843797","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Hygienic research on new soap preparations for intensive laundry use]. [集约洗衣用新型皂制剂的卫生研究]。
Problemi na khigienata Pub Date : 1993-01-01
S Uzunova, I Iordanova, A Baĭnova, A Tachev, T Ivanov
{"title":"[Hygienic research on new soap preparations for intensive laundry use].","authors":"S Uzunova,&nbsp;I Iordanova,&nbsp;A Baĭnova,&nbsp;A Tachev,&nbsp;T Ivanov","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The purpose of the study is to establish hygienic properties of the new preparations for intensive washing and their effect on the skin of man. Examinations are performed on 5 new washing preparations from firm \"Verila\": \"Linda\" (from the producer and from the trade network from the country--Ruse, Blagoevgrad, Stara Zagora, Pleven, Cherven Bryag, Plovdiv and Dobrich), recipe No 1, 2, 3 and 4. Sanitary and chemical examinations are carried out: organoleptic indices, nonionogenic surface active substances, total content of surface active substances, content of carbamide, sodium carbonate, ammonium nitrate, formaldehyde and free alkali. Investigations are made on 125 volunteers for skin irritative and allergenic effect, with epicutaneous test before and after 30-day washing--respectively with 0.5% and 2% and with 5% and 20% of the washing preparations. The results point out the absence of ammonium nitrate and formaldehyde and compliance with the content of the composition of the declared expenditure norms (except of \"Linda\" from the trade network of the country). There are no reactions of skin irritation and allergy in neither of the subjects with all washing preparations. Recommendations are given to the producer for observing the technological discipline and requirements to the packings.</p>","PeriodicalId":20520,"journal":{"name":"Problemi na khigienata","volume":"18 ","pages":"62-72"},"PeriodicalIF":0.0,"publicationDate":"1993-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18843800","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[An estimation of the prevalence of risk factors for the cardiovascular system among female telephone operators]. [对女性电话接线员心血管系统危险因素流行程度的估计]。
Problemi na khigienata Pub Date : 1993-01-01
E Ivanovich, D Kolarova
{"title":"[An estimation of the prevalence of risk factors for the cardiovascular system among female telephone operators].","authors":"E Ivanovich,&nbsp;D Kolarova","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The dissemination of the standard risk factors for the cardiovascular system--smoking, family history of hypertension and abnormal weight in telephone operators is evaluated by including one, two or three of these factors (p = 260). A high relative part is taken by persons in the presence of the evaluated factors--75.8%, as the most highly spread is the factor \"smoking\" (58.8%) and smoking and family predisposition (15.4\"). In persons with high blood pressure the dissemination of one or two of the examined risk factors is nearly the same, with heightened presence of \"smoking and abnormal weight\". In spite of the lack correlation between the studied risk factors and the arterial blood pressure, their dissemination on a large scale as well as the specific character of the telephone operators work certify a heightened risk of diseases of the cardiovascular system and the necessity of special attention to these endangered people.</p>","PeriodicalId":20520,"journal":{"name":"Problemi na khigienata","volume":"18 ","pages":"79-88"},"PeriodicalIF":0.0,"publicationDate":"1993-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18843802","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Changes in the blood system under chronic toxic exposure]. [慢性毒性暴露下血液系统的变化]。
Problemi na khigienata Pub Date : 1993-01-01
V Khristeva, N Mirchev
{"title":"[Changes in the blood system under chronic toxic exposure].","authors":"V Khristeva,&nbsp;N Mirchev","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>On the basis of accumulated experience from the numerous investigations of the elements of the peripheral blood in workers of different areas in industry and agriculture a classification is made of the injuries of the blood system under chronic toxic effects. Results from the peripheral blood state of 200 workers with chronic exposure to benzol and other aromatic hydrocarbons are given, as well as for 155 agricultural workers in contact with pesticides for many years and 308 children of the region with polluted by heavy metals (mainly lead) environment. Attention is drawn, that both the acute intoxications and chronic toxic effects have provoking role for the manifestation of concealed congenital, not rarely genetically stimulated insufficiency of Gl-6-PHD, which is manifested clinically as haemolytic anemia and secretly proceeding hemoglobinopathies, which clinically develop as thalassemia at entering of toxic doses of drugs, heavy metals, pesticides in the organism.</p>","PeriodicalId":20520,"journal":{"name":"Problemi na khigienata","volume":"18 ","pages":"97-105"},"PeriodicalIF":0.0,"publicationDate":"1993-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18843804","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[The acute toxicity of a bacterial insecticidal preparation containing a beta-exotoxin]. [含有-外毒素的细菌杀虫制剂的急性毒性]。
Problemi na khigienata Pub Date : 1993-01-01
Zh Khalkova, Kh Zaĭkov, G Antov, S Dinoeva
{"title":"[The acute toxicity of a bacterial insecticidal preparation containing a beta-exotoxin].","authors":"Zh Khalkova,&nbsp;Kh Zaĭkov,&nbsp;G Antov,&nbsp;S Dinoeva","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The acute toxicity of a new Bulgarian bioinsecticide preparation is determined, produced on the basis of Bacillus thuringiensis containing 0.1% beta-exotoxin by oral, dermal, inhalational and intraperitoneal introduction in experimental animals. The evaluation of the toxicity is performed by a complex of toxicometric, integral, haematologic and pathologicoanatomic methods according to the WHO and USA criteria for studying the safety of the microbic agents for plant protection. It is already established that the preparation introduced orally in dose 10,000 mg.kg-1 (1.6.10(11) cell kg.-1 10 micrograms.kg-1 beta exotoxin), applied dermally in dose 6000 mg.kg-1 (9.6.10(10), 6 micrograms.kg-1 beta exotoxin) and in concentration 300 mg.m-3 (4.8.10(10) cell m-3, 300 micrograms.m-3 beta exotoxin) provokes no lethality, intoxication and changes in the integral, haematologic and pathologicoanatomic studies of test animals. LD50 at intraperitoneal introduction in white rats is 387.20 mg (6.2.10(10), kg-1, 387.2 micrograms kg-1 beta exotoxin) for male and 364.0 mg kg-1 (0.58.10(9) kg-1 364.0 micrograms kg-1 beta exotoxin) for female animals. The investigations point out that according to rate of acute toxicity the bacterial preparation containing 0.1% beta exotoxin is referred to the low toxic substances and reveals no danger for acute oral, dermal and inhalational poisonings when the regulations for production and use are observed.</p>","PeriodicalId":20520,"journal":{"name":"Problemi na khigienata","volume":"18 ","pages":"114-24"},"PeriodicalIF":0.0,"publicationDate":"1993-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18843938","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Skin reactivity and the biological assessment of chromium exposure]. [皮肤反应性和铬暴露的生物学评价]。
Problemi na khigienata Pub Date : 1993-01-01
N Madzhunov, Z Zaprianov, R Georgieva
{"title":"[Skin reactivity and the biological assessment of chromium exposure].","authors":"N Madzhunov,&nbsp;Z Zaprianov,&nbsp;R Georgieva","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Subject to the examination are 140 workers from the plant for hydraulic products \"Iv. Tenev\", town of Yambol. The dermatological examination embraces 57 workers from shop 21, 49 from shop 24 and control group of 24 persons. The examination establishes skin changes in 24.6% of the workers from shop 21 and in 38.7% in those from shop 24. In the same workers were proved occupational dermatoses respectively in 5.3% for these of the first shop and in 14.3% for those of the second shop. The results of the test of 10 workers from shop 24 gave positivation of the test with 0.5% chromic anhydride at 10.5%. The studies for toxicokinetics of chromium in the examined workers proved its high values in urine, erythrocytes and nails. Raised chromium levels are established in the urine of those working with chromium in comparison with the control group (p 0.0001). There is a good correlation dependence between the chromium in urine and in erythrocytes (r = 0.71; n = 45%; p < 0.0001). Persons, eliminating significant quantities of chromium in the urine have higher values of chromium in erythrocytes, which shows that the chromium entering the organism of workers in contact with chromium is 6-valent. The connection with the chromium in urine and in nails is more lightly expressed and is statistically insignificant (r = 0.35; n = 29; p < 0.05), which is due to the fact that the chromium in urine reflects the near exposure in time, while chromium in nails--the level of exposure before 6-8 months.(ABSTRACT TRUNCATED AT 250 WORDS)</p>","PeriodicalId":20520,"journal":{"name":"Problemi na khigienata","volume":"18 ","pages":"167-75"},"PeriodicalIF":0.0,"publicationDate":"1993-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18844431","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[The assessment of the occupational risk for skin diseases in workers at the Storgoziia Plant, Pleven]. [对普列文Storgoziia工厂工人皮肤病职业风险的评估]。
Problemi na khigienata Pub Date : 1993-01-01
N Madzhunov, M Nosko
{"title":"[The assessment of the occupational risk for skin diseases in workers at the Storgoziia Plant, Pleven].","authors":"N Madzhunov,&nbsp;M Nosko","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>A dermatological examination is performed on 95 workers (43 men and 52 women). In order to differentiate the type of contact dermatitis in connection with the expert examination of the skin changes in 20 workers was carried out epicutaneous test by specialized series PVH dust (pure), PVH--dust, containing dyes, by titanium oxide, with lead stearat and with paraloid, which is on acrylic base--all in concentrations 2% in carrier oil. It is established that in 26.3% of the examined are registered general skin diseases. In 7.4% are proved occupational skin diseases and in 3.2% allergic, in 4.2%--irritative.</p>","PeriodicalId":20520,"journal":{"name":"Problemi na khigienata","volume":"18 ","pages":"175-80"},"PeriodicalIF":0.0,"publicationDate":"1993-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18844432","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[The effect of air pollution on the allergic reactivity of the population]. [空气污染对人群过敏反应的影响]。
Problemi na khigienata Pub Date : 1993-01-01
T Antova
{"title":"[The effect of air pollution on the allergic reactivity of the population].","authors":"T Antova","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>An epidemiological study was carried out in several regions in Bulgaria polluted by industry and motor vehicle transport. The investigation included monitoring of ambient air pollution, a questionnaire study of 13040 persons, and allergological/immunological testing of representative groups of population. The testing was performed on persons selected by the questionnaire study, who were not exposed professionally to toxicants. The ambient air was contaminated by particulates and gaseous contaminants in the majority of the studies areas. The questionnaire study revealed an increased incidence of complaints indicative of allergic reactions, such as recurring skin eruptions, allergic rhinitis, conjunctivitis, asthmatic bronchitis. The positive skin tests were twice as common among the residents of polluted areas as compared to control. A decreased activity of the complement and increased levels of immunoglobulins (IgG, IgA, IgM) were found in the exposed population. The changes found in the study suggest a health risk for the population created by air pollution.</p>","PeriodicalId":20520,"journal":{"name":"Problemi na khigienata","volume":"18 ","pages":"20-31"},"PeriodicalIF":0.0,"publicationDate":"1993-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18844434","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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