Problems Of Biological, Medical And Pharmaceutical Chemistry最新文献

{"title":"STUDYING OF THE ANTI-ISCHEMIC EFFECT OF OROSTACHYS SPINOSA DRY EXTRACT IN CAROTID ARTERIES BILATERAL OCCLUSION IN WHITE RATS","authors":"Y. Razuvaeva, E. A. Bayandueva, A. Toropova, I. G. Nikolaeva","doi":"10.29296/25877313-2022-07-01","DOIUrl":"https://doi.org/10.29296/25877313-2022-07-01","url":null,"abstract":"","PeriodicalId":20508,"journal":{"name":"Problems Of Biological, Medical And Pharmaceutical Chemistry","volume":"19 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85217753","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Biochemical and spectral analysis of the impact of office teeth whitening on the organic composition of oral fluid","authors":"E. Ryskina, O. A. Magsumova, M. Postnikov, S. Chigarina, O.E. Simanovskaya, M. Korchagina, V. Polkanova","doi":"10.29296/25877313-2022-10-07","DOIUrl":"https://doi.org/10.29296/25877313-2022-10-07","url":null,"abstract":"","PeriodicalId":20508,"journal":{"name":"Problems Of Biological, Medical And Pharmaceutical Chemistry","volume":"15 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79705874","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Chemometric approach to investigation of the role of adipose tissue as a target for toxic metal effects","authors":"A. Skalny, V. Nikolenko, T. Fatkhudinov, Jung-Su Chang, G.D. Morozova, G. Zolotenkova, Shih-Yi Huang, A. Tinkov","doi":"10.29296/25877313-2022-12-01","DOIUrl":"https://doi.org/10.29296/25877313-2022-12-01","url":null,"abstract":"","PeriodicalId":20508,"journal":{"name":"Problems Of Biological, Medical And Pharmaceutical Chemistry","volume":"118 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80282953","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"EXPERIMENTAL MORPHOGENESIS OF AMOMUM TSAO-KO CREVOST & LEMARIE. IN VITRO CULTURE","authors":"K. V. Quyet, H. Nguyen, E. Kalashnikova, R. Kirakosyan","doi":"10.29296/25877313-2022-07-08","DOIUrl":"https://doi.org/10.29296/25877313-2022-07-08","url":null,"abstract":"","PeriodicalId":20508,"journal":{"name":"Problems Of Biological, Medical And Pharmaceutical Chemistry","volume":"34 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89762154","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Features of metabolism and spectrum of action of selenium, possibilities of application of selene-containing food supplements under SARS-CoV-2 pandemic conditions","authors":"E. Okladnikova, T. Potupchik, L. Evert, O. Veselova, Y. Shirobokov","doi":"10.29296/25877313-2022-03-04","DOIUrl":"https://doi.org/10.29296/25877313-2022-03-04","url":null,"abstract":"This article provides a literary review of domestic and foreign sources reflecting the prevalence of selenium (Se) in the environment, its metabolism in the human body. It has been shown that Se deficiency is associated with cardiovascular diseases, disorders in the endocrine and reproductive system. The role of Se in the antioxidant defense system that supports the redox homeostasis of the cell and the body, for example, in viral infections, one of the causes of which is oxidative stress, is presented. The above sources also reflect the positive role of Se in viral infections, including, with a new coronavirus infection caused by the SARS-CoV-2 virus, since Se is necessary for the differentiation and proliferation of a number of immune cells involved in the processes of innate and adaptive immunity. It has been proven that in moderate doses, the Se supplement increases the proliferation of T cells and the activity of natural killer cells. In this regard, it is possible to recommend taking dietary supplements containing Se in high-risk areas and /or shortly after suspected infection with SARS-CoV-2. Positive research results, as well as a good safety profile, indicate the possibility of using biologically active food additives containing Se in complex therapy, in particular SELENBIO for women in disorders of the cardiovascular, endocrine, reproductive system, as well as in infectious diseases. (English) [ FROM AUTHOR] Представлен литературный обзор отечественных и зарубежных источников, отражающих распространенность селена (Se) в окружающей среде, его метаболизм в организме человека. Показано, что дефицит Se ассоциируется с сердечно-сосудистыми заболеваниями, нарушениями в эндокринной и репродуктивной системах. Представлена роль Se в системе антиоксидантной защиты, поддерживающей окислительно-восстановительный гомеостаз клетки и организма, например в случае вирусных инфекций, одной из причин которых является окислительный стресс. В приведенных источниках отражена также положительная роль Se при вирусных инфекциях, в том числе при новой коронавирусной инфекции, вызванной вирусом SARS-CoV-2, поскольку Se необходим для дифференцировки и пролиферации ряда иммунных клеток, участвующих в процессах врожденного и адаптивного иммунитета. Доказано, что в умеренных дозах добавка Se увеличивает пролиферацию Т-клеток и активность естественных клеток-киллеров. В связи с этим можно рекомендовать прием пищевых добавок, содержащих Se, в зонах высокого риска и/или вскоре после подозрения на инфицирование SARS-CoV-2. Положительные результаты исследований, а также хороший профиль безопасности свидетельствуют о возможности применения в комплексной терапии биологически активных пищевых добавок, содержащих Se, в частности препарат «SELENBIO for women» при нарушениях сердечно-сосудистой, эндокринной, репродуктивной систем, а также при инфекционных заболеваниях. (Russian) [ FROM AUTHOR] Copyright of Problems of Biological, Medical & Pharmaceutical Chemistry is the proper","PeriodicalId":20508,"journal":{"name":"Problems Of Biological, Medical And Pharmaceutical Chemistry","volume":"18 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79013789","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Benefits of composition combined herbal drug of sedative action","authors":"Hajjar Fadi, O. G. Potanina, R. Abramovich","doi":"10.29296/25877313-2022-06-06","DOIUrl":"https://doi.org/10.29296/25877313-2022-06-06","url":null,"abstract":"","PeriodicalId":20508,"journal":{"name":"Problems Of Biological, Medical And Pharmaceutical Chemistry","volume":"139 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75052977","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Physicochemical properties of zinc oxide nanoparticles modified with betulin diphosphate","authors":"A.A. Balakireva, D. Panteleev, D. Malygina, D. Orekhov, I.V. Spitskaya, N. Melnikova","doi":"10.29296/25877313-2022-03-01","DOIUrl":"https://doi.org/10.29296/25877313-2022-03-01","url":null,"abstract":"","PeriodicalId":20508,"journal":{"name":"Problems Of Biological, Medical And Pharmaceutical Chemistry","volume":"59 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79469167","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A retrospective analysis of the experimental and clinical study of pasenin, a drug for the treatment of dyslipidemia in patients with diabetes mellitus","authors":"V.V. Karabayeva, L. Krepkova, I. Lupanova, A. N. Babenko, P. G. Mizina","doi":"10.29296/25877313-2022-10-08","DOIUrl":"https://doi.org/10.29296/25877313-2022-10-08","url":null,"abstract":"","PeriodicalId":20508,"journal":{"name":"Problems Of Biological, Medical And Pharmaceutical Chemistry","volume":"43 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79005835","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Production of interleukin-6 by resting hybridoma endothelial cells of the EA.HY926 line","authors":"U. Saginbaev","doi":"10.29296/25877313-2022-05-02","DOIUrl":"https://doi.org/10.29296/25877313-2022-05-02","url":null,"abstract":"","PeriodicalId":20508,"journal":{"name":"Problems Of Biological, Medical And Pharmaceutical Chemistry","volume":"10 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79909285","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Remodeling of the left atrium in patients with 4-5 stage chronic kidney disease","authors":"I. T. Murkamilov, K. Aitbaev, Z. Murkamilova, V. Fomin, I. Kudaibergenova, F. Yusupov","doi":"10.29296/25877313-2022-03-03","DOIUrl":"https://doi.org/10.29296/25877313-2022-03-03","url":null,"abstract":"","PeriodicalId":20508,"journal":{"name":"Problems Of Biological, Medical And Pharmaceutical Chemistry","volume":"480 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77779263","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}