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Proceedings of 7th International Electronic Conference on Medicinal Chemistry最新文献

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Review of biological activities and medicinal significance of quercetin 槲皮素的生物活性及药用意义综述
Proceedings of 7th International Electronic Conference on Medicinal Chemistry Pub Date : 2021-11-03 DOI: 10.3390/ecmc2021-11509
Ana D. Amic, Marija Mirosavljević
{"title":"Review of biological activities and medicinal significance of quercetin","authors":"Ana D. Amic, Marija Mirosavljević","doi":"10.3390/ecmc2021-11509","DOIUrl":"https://doi.org/10.3390/ecmc2021-11509","url":null,"abstract":"","PeriodicalId":20499,"journal":{"name":"Proceedings of 7th International Electronic Conference on Medicinal Chemistry","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-11-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90053326","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Prediciton of skin permeability of compounds using IAM chromatographic and calculated descriptors 用IAM色谱和计算描述符预测化合物的透皮性
Proceedings of 7th International Electronic Conference on Medicinal Chemistry Pub Date : 2021-11-03 DOI: 10.3390/ecmc2021-11493
A. Sobańska, E. Brzezińska
{"title":"Prediciton of skin permeability of compounds using IAM chromatographic and calculated descriptors","authors":"A. Sobańska, E. Brzezińska","doi":"10.3390/ecmc2021-11493","DOIUrl":"https://doi.org/10.3390/ecmc2021-11493","url":null,"abstract":"","PeriodicalId":20499,"journal":{"name":"Proceedings of 7th International Electronic Conference on Medicinal Chemistry","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-11-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90208546","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Development of ionic liquids and eutectic systems for drug-formulations 离子液体和药物配方共晶体系的发展
Proceedings of 7th International Electronic Conference on Medicinal Chemistry Pub Date : 2021-11-03 DOI: 10.3390/ecmc2021-11568
M. Jacinto, and C. Santos, M. Dionísio, Miguel M. Santos, Luís Branco, Ž. Petrovski
{"title":"Development of ionic liquids and eutectic systems for drug-formulations","authors":"M. Jacinto, and C. Santos, M. Dionísio, Miguel M. Santos, Luís Branco, Ž. Petrovski","doi":"10.3390/ecmc2021-11568","DOIUrl":"https://doi.org/10.3390/ecmc2021-11568","url":null,"abstract":"","PeriodicalId":20499,"journal":{"name":"Proceedings of 7th International Electronic Conference on Medicinal Chemistry","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-11-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89771151","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Novel of (‒)-menthone and (+)-camphor hydrazones as promising agents with dual effects (-)-薄荷酮和(+)-樟脑腙具有双重作用
Proceedings of 7th International Electronic Conference on Medicinal Chemistry Pub Date : 2021-11-03 DOI: 10.3390/ecmc2021-11559
M. Nesterkina, Y. Boiko, I. Kravchenko
{"title":"Novel of (‒)-menthone and (+)-camphor hydrazones as promising agents with dual effects","authors":"M. Nesterkina, Y. Boiko, I. Kravchenko","doi":"10.3390/ecmc2021-11559","DOIUrl":"https://doi.org/10.3390/ecmc2021-11559","url":null,"abstract":"","PeriodicalId":20499,"journal":{"name":"Proceedings of 7th International Electronic Conference on Medicinal Chemistry","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-11-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87771008","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Colon specific delivery system based on ethylcellulose-alginates microspheres loaded with mesalazine 基于乙基纤维素-海藻酸盐微球负载美沙拉嗪的结肠特异性递送系统
Proceedings of 7th International Electronic Conference on Medicinal Chemistry Pub Date : 2021-11-03 DOI: 10.3390/ecmc2021-11500
Merir Roufaida
{"title":"Colon specific delivery system based on ethylcellulose-alginates microspheres loaded with mesalazine","authors":"Merir Roufaida","doi":"10.3390/ecmc2021-11500","DOIUrl":"https://doi.org/10.3390/ecmc2021-11500","url":null,"abstract":"","PeriodicalId":20499,"journal":{"name":"Proceedings of 7th International Electronic Conference on Medicinal Chemistry","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-11-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87876073","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Triazole-indole hybrid molecules as antifungal agents: Design, synthesis and biological activity, and beyond 作为抗真菌剂的三唑-吲哚杂化分子:设计、合成和生物活性等
Proceedings of 7th International Electronic Conference on Medicinal Chemistry Pub Date : 2021-11-03 DOI: 10.3390/ecmc2021-11577
M. Le Borgne, N. Lebouvier, F. Pagniez, Y. Na, Angélique Mularoni, Marie Brossier, J. Guillon, C. Simons, R. Abagyan, R. Hartmann, P. Le Pape
{"title":"Triazole-indole hybrid molecules as antifungal agents: Design, synthesis and biological activity, and beyond","authors":"M. Le Borgne, N. Lebouvier, F. Pagniez, Y. Na, Angélique Mularoni, Marie Brossier, J. Guillon, C. Simons, R. Abagyan, R. Hartmann, P. Le Pape","doi":"10.3390/ecmc2021-11577","DOIUrl":"https://doi.org/10.3390/ecmc2021-11577","url":null,"abstract":"Invasive fungal infections have increased in frequency and severity over the last twenty years as a result of an increasing number of immunocompromised hosts due to cancer chemotherapy, organ and bone marrow transplantation, or therapy against autoimmune and inflammatory disorders. Candida species (spp.) are among the most common pathogens. Candida albicans is the main cause of candidiasis. In addition non-albicans Candida spp. are becoming more and more involved in nosocomial infections. The emergence of resistance to conventional treatments (e.g. fluconazole) make healing successes weaker. It is therefore urgent to continue efforts to develop new antifungal agents. A series of 2-aryl-3-azolyl-1indolyl-propan-2-ols was designed as new analogs of fluconazole by replacing one of its two triazole moieties by an indole scaffold. Two different chemical pathways were developed; the first one included seven steps and the second one only three. The pharmacomodulation works have enabled us to identify a molecule with a strong biological impact on fungi. Numerous experiments progressively confirmed the high potential of this hybrid molecule as antifungal agent. In this presentation, all aspects of medicinal chemistry will be addressed.","PeriodicalId":20499,"journal":{"name":"Proceedings of 7th International Electronic Conference on Medicinal Chemistry","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-11-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86861798","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Structural Insight into the interaction of flavonoids with aldose reductase 黄酮类化合物与醛糖还原酶相互作用的结构研究
Proceedings of 7th International Electronic Conference on Medicinal Chemistry Pub Date : 2021-11-03 DOI: 10.3390/ecmc2021-11497
Manivannan Elangovan, N. Moorthy, K. Chandra Bose
{"title":"Structural Insight into the interaction of flavonoids with aldose reductase","authors":"Manivannan Elangovan, N. Moorthy, K. Chandra Bose","doi":"10.3390/ecmc2021-11497","DOIUrl":"https://doi.org/10.3390/ecmc2021-11497","url":null,"abstract":"","PeriodicalId":20499,"journal":{"name":"Proceedings of 7th International Electronic Conference on Medicinal Chemistry","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-11-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79183234","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
miRNA Detection for non-small cell lung cancer diagnosis miRNA检测在非小细胞肺癌诊断中的应用
Proceedings of 7th International Electronic Conference on Medicinal Chemistry Pub Date : 2021-11-03 DOI: 10.3390/ecmc2021-11506
Carla Cruz, André Rico, F. Sousa, Bernardo Teixeira, D. Alexandre
{"title":"miRNA Detection for non-small cell lung cancer diagnosis","authors":"Carla Cruz, André Rico, F. Sousa, Bernardo Teixeira, D. Alexandre","doi":"10.3390/ecmc2021-11506","DOIUrl":"https://doi.org/10.3390/ecmc2021-11506","url":null,"abstract":"","PeriodicalId":20499,"journal":{"name":"Proceedings of 7th International Electronic Conference on Medicinal Chemistry","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-11-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86199508","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Selective inhibition of the iNOS by acetamidine derivatives 乙酰氨基胺衍生物对iNOS的选择性抑制
Proceedings of 7th International Electronic Conference on Medicinal Chemistry Pub Date : 2021-11-03 DOI: 10.3390/ecmc2021-11491
R. Amoroso
{"title":"Selective inhibition of the iNOS by acetamidine derivatives","authors":"R. Amoroso","doi":"10.3390/ecmc2021-11491","DOIUrl":"https://doi.org/10.3390/ecmc2021-11491","url":null,"abstract":"","PeriodicalId":20499,"journal":{"name":"Proceedings of 7th International Electronic Conference on Medicinal Chemistry","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-11-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85633691","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Effects of propranolol and haloperidol on non-target organisms: A case study with amphibians 心得安和氟哌啶醇对非靶生物的影响:以两栖动物为例研究
Proceedings of 7th International Electronic Conference on Medicinal Chemistry Pub Date : 2021-11-03 DOI: 10.3390/ecmc2021-11540
Miguel Oliveira, Filipa Morais, Mónica Almeida, I. Lopes
{"title":"Effects of propranolol and haloperidol on non-target organisms: A case study with amphibians","authors":"Miguel Oliveira, Filipa Morais, Mónica Almeida, I. Lopes","doi":"10.3390/ecmc2021-11540","DOIUrl":"https://doi.org/10.3390/ecmc2021-11540","url":null,"abstract":"","PeriodicalId":20499,"journal":{"name":"Proceedings of 7th International Electronic Conference on Medicinal Chemistry","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-11-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85984158","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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