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P06.01 Gain-of-function CARD11 signalling in B cells causes pathological lymphoproliferative disease in mice which is strictly dependent on MALT1 activity P06.01 B 细胞中功能缺失的 CARD11 信号导致小鼠病理性淋巴组织增生性疾病，而这种疾病严格依赖于 MALT1 的活性
Poster presentations Pub Date : 2024-03-01 DOI: 10.1136/jitc-2024-itoc10.42
A. Kratzert, E. Morrish, SJ Keppler, J. Ruland
{"title":"P06.01 Gain-of-function CARD11 signalling in B cells causes pathological lymphoproliferative disease in mice which is strictly dependent on MALT1 activity","authors":"A. Kratzert, E. Morrish, SJ Keppler, J. Ruland","doi":"10.1136/jitc-2024-itoc10.42","DOIUrl":"https://doi.org/10.1136/jitc-2024-itoc10.42","url":null,"abstract":"","PeriodicalId":20386,"journal":{"name":"Poster presentations","volume":"17 17","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140277344","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
P76 Established risk alleles at HLA-A, -DPB1, -DQB1 and -DRB1 for systemic lupus erythematosus associate with distinct clinical manifestations P76 系统性红斑狼疮的 HLA-A、-DPB1、-DQB1 和 -DRB1 风险等位基因与不同的临床表现有关
Poster presentations Pub Date : 2024-03-01 DOI: 10.1136/lupus-2024-el.130
Henrik Christian Bidstrup Leffers, I. Jónsdóttir, S. Saevarsdottir, O. B. Pedersen, A. Troldborg, Anne Voss, S. Kristensen, Jesper Lindhardsen, Prabhat Kumar, A. Linauskas, Lars Juul, N. Krogh, Bent Deleuran, Lene Dreyer, Michael Schwinn, L. Thørner, L. Hindhede, C. Erikstrup, S. Ostrowski, S. Brunak, Kári Stefánsson, Søren Jacobsen
{"title":"P76 Established risk alleles at HLA-A, -DPB1, -DQB1 and -DRB1 for systemic lupus erythematosus associate with distinct clinical manifestations","authors":"Henrik Christian Bidstrup Leffers, I. Jónsdóttir, S. Saevarsdottir, O. B. Pedersen, A. Troldborg, Anne Voss, S. Kristensen, Jesper Lindhardsen, Prabhat Kumar, A. Linauskas, Lars Juul, N. Krogh, Bent Deleuran, Lene Dreyer, Michael Schwinn, L. Thørner, L. Hindhede, C. Erikstrup, S. Ostrowski, S. Brunak, Kári Stefánsson, Søren Jacobsen","doi":"10.1136/lupus-2024-el.130","DOIUrl":"https://doi.org/10.1136/lupus-2024-el.130","url":null,"abstract":"","PeriodicalId":20386,"journal":{"name":"Poster presentations","volume":"28 3","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140277662","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
P158 Belimumab for the treatment of systemic lupus erythematosus in the real world: a single center study P158 现实世界中治疗系统性红斑狼疮的贝利木单抗：一项单中心研究
Poster presentations Pub Date : 2024-03-01 DOI: 10.1136/lupus-2024-el.212
P. M. Calabuig, Jorge Juan Fragío Gil, R. G. Mazarío, Sara Moner Marín, Laura Salvador Maicas, Mireia Sanmartín Martínez, A. Cid, Juan Jóse Lerma Garrido, C. M. Almela, Cristina Campos Fernández
{"title":"P158 Belimumab for the treatment of systemic lupus erythematosus in the real world: a single center study","authors":"P. M. Calabuig, Jorge Juan Fragío Gil, R. G. Mazarío, Sara Moner Marín, Laura Salvador Maicas, Mireia Sanmartín Martínez, A. Cid, Juan Jóse Lerma Garrido, C. M. Almela, Cristina Campos Fernández","doi":"10.1136/lupus-2024-el.212","DOIUrl":"https://doi.org/10.1136/lupus-2024-el.212","url":null,"abstract":"","PeriodicalId":20386,"journal":{"name":"Poster presentations","volume":"18 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140278010","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
P01.08 Discovery of CRD1601, a potent and selective HPK1 inhibitor with robust in vivo anti-cancer activity P01.08 发现具有强大体内抗癌活性的强效选择性 HPK1 抑制剂 CRD1601
Poster presentations Pub Date : 2024-03-01 DOI: 10.1136/jitc-2024-itoc10.18
R. Shrivastava, M. Banerjee, D. Pryde, S. Middya, S. Debnath, A. Middya, D. Yadav, N. Mane, N. Rawat, R. Ghosh, A. Gautam, M. Padaliya, S. Bano, S. Basu, A. Surya
{"title":"P01.08 Discovery of CRD1601, a potent and selective HPK1 inhibitor with robust in vivo anti-cancer activity","authors":"R. Shrivastava, M. Banerjee, D. Pryde, S. Middya, S. Debnath, A. Middya, D. Yadav, N. Mane, N. Rawat, R. Ghosh, A. Gautam, M. Padaliya, S. Bano, S. Basu, A. Surya","doi":"10.1136/jitc-2024-itoc10.18","DOIUrl":"https://doi.org/10.1136/jitc-2024-itoc10.18","url":null,"abstract":"","PeriodicalId":20386,"journal":{"name":"Poster presentations","volume":"40 ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140278338","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
P04.04 Single cell transcriptomics reveals cancer associated fibroblasts enable modeling of tumor associated macrophage like phenotypes and treatment responses in primary colorectal cancer organoid cultures P04.04 单细胞转录组学揭示癌症相关成纤维细胞，为原发性结直肠癌类器官培养物中的肿瘤相关巨噬细胞表型和治疗反应建模
Poster presentations Pub Date : 2024-03-01 DOI: 10.1136/jitc-2024-itoc10.39
J. Kabiljo, A. Theophil, J. Homola, A. Renner, J. Karall, N. Hartman, S. Stang, L. Tran, J. Laengle, A. Kulu, A. Chen, M. Fabits, V. Atanasova, H. Walczak, D. Herndler-Brandstetter, G. Egger, H. Dolznig, A. Kusienicka, M. Farlik, M. Bergmann
{"title":"P04.04 Single cell transcriptomics reveals cancer associated fibroblasts enable modeling of tumor associated macrophage like phenotypes and treatment responses in primary colorectal cancer organoid cultures","authors":"J. Kabiljo, A. Theophil, J. Homola, A. Renner, J. Karall, N. Hartman, S. Stang, L. Tran, J. Laengle, A. Kulu, A. Chen, M. Fabits, V. Atanasova, H. Walczak, D. Herndler-Brandstetter, G. Egger, H. Dolznig, A. Kusienicka, M. Farlik, M. Bergmann","doi":"10.1136/jitc-2024-itoc10.39","DOIUrl":"https://doi.org/10.1136/jitc-2024-itoc10.39","url":null,"abstract":"","PeriodicalId":20386,"journal":{"name":"Poster presentations","volume":"100 8","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140278498","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
P140 Pregnancy and systemic lupus erythematosus: experience in a pregnancy clinic P140 妊娠与系统性红斑狼疮：妊娠诊所的经验
Poster presentations Pub Date : 2024-03-01 DOI: 10.1136/lupus-2024-el.194
Elena Heras-Recuero, Antía García-Fernández, Fernando Rengifo-García, Teresa Blázquez-Sánchez, Raquel Senosiain-Echarte, Miguel Álvaro-Navidad, M. A. González-Gay, Juan Antonio Martínez-López
{"title":"P140 Pregnancy and systemic lupus erythematosus: experience in a pregnancy clinic","authors":"Elena Heras-Recuero, Antía García-Fernández, Fernando Rengifo-García, Teresa Blázquez-Sánchez, Raquel Senosiain-Echarte, Miguel Álvaro-Navidad, M. A. González-Gay, Juan Antonio Martínez-López","doi":"10.1136/lupus-2024-el.194","DOIUrl":"https://doi.org/10.1136/lupus-2024-el.194","url":null,"abstract":"","PeriodicalId":20386,"journal":{"name":"Poster presentations","volume":"158 ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140278874","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
P105 NEX-T CD19 chimeric antigen receptor (CAR) T-cell therapy CC-97540 (BMS-986353): Preclinical and translational evidence of deep B-cell depletion suitable for study in severe refractory autoimmune diseases P105 NEX-T CD19嵌合抗原受体（CAR）T细胞疗法CC-97540（BMS-986353）：适用于严重难治性自身免疫性疾病研究的深度 B 细胞耗竭的临床前和转化证据
Poster presentations Pub Date : 2024-03-01 DOI: 10.1136/lupus-2024-el.159
Georg Schett, Tatyana Feldman, Jeremy Abramson, Boyu Hu, Fabien Müller, Ashley Koegel, Jerill Thorpe, Ruth Salmon, Fan Wu, Divya Varun, Alison Maier, David Kugler, Matthew Westoby, Nikolay Delev, Amitkumar Mehta
{"title":"P105 NEX-T CD19 chimeric antigen receptor (CAR) T-cell therapy CC-97540 (BMS-986353): Preclinical and translational evidence of deep B-cell depletion suitable for study in severe refractory autoimmune diseases","authors":"Georg Schett, Tatyana Feldman, Jeremy Abramson, Boyu Hu, Fabien Müller, Ashley Koegel, Jerill Thorpe, Ruth Salmon, Fan Wu, Divya Varun, Alison Maier, David Kugler, Matthew Westoby, Nikolay Delev, Amitkumar Mehta","doi":"10.1136/lupus-2024-el.159","DOIUrl":"https://doi.org/10.1136/lupus-2024-el.159","url":null,"abstract":"","PeriodicalId":20386,"journal":{"name":"Poster presentations","volume":"139 3","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140280329","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
P63 Time is important: implications of disease duration and age for systemic erythematosus lupus neuroimaging P63 时间很重要：病程和年龄对系统性红斑狼疮神经影像学的影响
Poster presentations Pub Date : 2024-03-01 DOI: 10.1136/lupus-2024-el.117
Luana Barros de Lima, Lucas Bomfim, Laís Pedroza, Jorge Arthur Coelho, Thiago Fragoso
{"title":"P63 Time is important: implications of disease duration and age for systemic erythematosus lupus neuroimaging","authors":"Luana Barros de Lima, Lucas Bomfim, Laís Pedroza, Jorge Arthur Coelho, Thiago Fragoso","doi":"10.1136/lupus-2024-el.117","DOIUrl":"https://doi.org/10.1136/lupus-2024-el.117","url":null,"abstract":"","PeriodicalId":20386,"journal":{"name":"Poster presentations","volume":"685 ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140281101","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
P82 Health literacy status and its correlates among patients with lupus nephritis P82 狼疮性肾炎患者的健康素养状况及其相关因素
Poster presentations Pub Date : 2024-03-01 DOI: 10.1136/lupus-2024-el.136
Cameron Bonthrone, Luxme Nadarajah, A. Pákozdi, Debasish Pyne, A. Cove-Smith, R. Rajakariar
{"title":"P82 Health literacy status and its correlates among patients with lupus nephritis","authors":"Cameron Bonthrone, Luxme Nadarajah, A. Pákozdi, Debasish Pyne, A. Cove-Smith, R. Rajakariar","doi":"10.1136/lupus-2024-el.136","DOIUrl":"https://doi.org/10.1136/lupus-2024-el.136","url":null,"abstract":"","PeriodicalId":20386,"journal":{"name":"Poster presentations","volume":"171 ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140283490","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
P100 Efficacy of anifrolumab in multi-refractory skin manifestations of systemic lupus erythematosus: case series P100 阿尼洛单抗治疗系统性红斑狼疮多重难治性皮肤表现的疗效：病例系列
Poster presentations Pub Date : 2024-03-01 DOI: 10.1136/lupus-2024-el.154
S. Flouda, E. Emmanouilidou, A. Karamanakos, G. Bertsias, Dimitrios T Boumpas, Antonios Fanouriakis
{"title":"P100 Efficacy of anifrolumab in multi-refractory skin manifestations of systemic lupus erythematosus: case series","authors":"S. Flouda, E. Emmanouilidou, A. Karamanakos, G. Bertsias, Dimitrios T Boumpas, Antonios Fanouriakis","doi":"10.1136/lupus-2024-el.154","DOIUrl":"https://doi.org/10.1136/lupus-2024-el.154","url":null,"abstract":"","PeriodicalId":20386,"journal":{"name":"Poster presentations","volume":"22 10","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140268241","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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