Point of Care: The Journal of Near-Patient Testing & Technology最新文献_第6页

Thromboelastography (TEG) Point-of-Care Diagnostic for Hemostasis Management 血栓弹性成像(TEG)即时诊断止血管理

Point of Care: The Journal of Near-Patient Testing & Technology Pub Date : 2018-03-01 DOI: 10.1097/POC.0000000000000156

J. Hartmann, D. Mason, Hardean E. Achneck

{"title":"Thromboelastography (TEG) Point-of-Care Diagnostic for Hemostasis Management","authors":"J. Hartmann, D. Mason, Hardean E. Achneck","doi":"10.1097/POC.0000000000000156","DOIUrl":"https://doi.org/10.1097/POC.0000000000000156","url":null,"abstract":"Abstract Thromboelastography is a method of assessing the coagulation status of patients. Unlike standard laboratory–based coagulation tests (eg, prothrombin time and activated partial thromboplastin time), it provides a holistic, functional perspective on the entire coagulation process; and point-of-care application provides results more quickly. Across a wide range of clinical settings, thromboelastography can be used to assess the risk of bleeding or thromboembolic events and to guide management of hemostatic equilibrium. Until recently, the principal system for performing thromboelastography was the TEG 5000 analyzer. The TEG 6s system, which consists of the TEG 6s analyzer and disposable cartridges, measures the same properties as the TEG 5000 and was recently developed to increase the ease and precision with which thromboelastography is performed. By measuring the velocity of clot formation, the strength of the clot, contributions of fibrinogen and platelets to clot strength, and the speed/extent of fibrinolysis, a comprehensive insight into the patient's coagulation status is gained. Treatment can then be individualized to ensure effective coagulation management while avoiding exposure to unnecessary treatment. Subsequently, the effect of treatment can be assessed to determine whether further intervention may be required. We review the clinical use of thromboelastography in trauma, cardiovascular surgery, liver transplantation, obstetrics, congenital bleeding disorders, and other settings. Increased uptake of thromboelastography has the potential to improve standards of patient care and to lead to health economic benefits.","PeriodicalId":20262,"journal":{"name":"Point of Care: The Journal of Near-Patient Testing & Technology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2018-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80896047","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 21

Validation of the Nova Point-of-Care Testing StatStrip &bgr;-Ketone Test in a Laboratory and Clinical Setting Nova即时护理测试StatStrip -酮测试在实验室和临床环境中的验证

Point of Care: The Journal of Near-Patient Testing & Technology Pub Date : 2018-03-01 DOI: 10.1097/POC.0000000000000155

S. Vandamme, Kore Van Mechelen, Hugo Cluckers, V. Van Hoof

引用次数: 0

The Effectiveness of Fetal Lactate Measurement in the Assessment of Fetal Acidemia Using StatStrip Lactate Meter 用StatStrip乳酸计测定胎儿乳酸在评估胎儿酸血症中的有效性

Point of Care: The Journal of Near-Patient Testing & Technology Pub Date : 2018-03-01 DOI: 10.1097/POC.0000000000000154

V. Olagundoye, S. Ijaz

引用次数: 0

Point-of-Care Abstracts From the 2017 American Association for Clinical Chemistry Meeting (Reprinted with permission) 2017年美国临床化学协会会议护理点摘要(经许可转载)

Point of Care: The Journal of Near-Patient Testing & Technology Pub Date : 2018-01-01 DOI: 10.1097/POC.0000000000000158

引用次数: 0

A First Impression of Point-of-Care Testing in Spain: Spanish Society of Clinical Biochemistry Survey Results 在西班牙的护理点测试的第一印象:西班牙社会临床生物化学调查结果

Point of Care: The Journal of Near-Patient Testing & Technology Pub Date : 2017-12-01 DOI: 10.1097/POC.0000000000000148

F. J. Lirón-Hernández, Paloma Oliver-Sáez, Catalina Sánchez-Mora, O. Rodríguez-Fraga

{"title":"A First Impression of Point-of-Care Testing in Spain: Spanish Society of Clinical Biochemistry Survey Results","authors":"F. J. Lirón-Hernández, Paloma Oliver-Sáez, Catalina Sánchez-Mora, O. Rodríguez-Fraga","doi":"10.1097/POC.0000000000000148","DOIUrl":"https://doi.org/10.1097/POC.0000000000000148","url":null,"abstract":"Abstract The use of point-of-care testing (POCT) technology has increased every year worldwide. In Spain, there are no data about how these tests are used and where they are performed, and there is no clear vision of what is the role of laboratory regarding these tests. The POCT Committee, in the Spanish Society of Clinical Biochemistry, carried out a survey in order to find out what the situation is with POCT in the country from a laboratory POCT manager's point of view. The survey had 19 questions: 3 for segmentation, 1 for opinion, 13 to obtain specific information about POCT in their hospitals, and 2 about personal information. To enable a response, a survey link was shared in the Spanish Society of Clinical Biochemistry Web page. Responses were obtained via Google Docs Web page, where coworkers were requested to fill in the survey. The survey was answered by 140 laboratories, but only 126 of the responses were considered valid. The survey results generally showed that the situation in Spain is similar to that in other countries as documented by similar national surveys on POCT. The survey also demonstrated room for improvement in POCT practices and a need for governmental regulation to improve POCT processes.","PeriodicalId":20262,"journal":{"name":"Point of Care: The Journal of Near-Patient Testing & Technology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2017-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80449117","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Accuracy of CoaguChek XS in Patients With Antiphospholipid Syndrome CoaguChek XS在抗磷脂综合征患者中的准确性

Point of Care: The Journal of Near-Patient Testing & Technology Pub Date : 2017-12-01 DOI: 10.1097/POC.0000000000000149

James R. Taylor, C. Richter, Chris Lindamood, Xinyu Liu, M. Zumberg, Brad Fletcher

{"title":"Accuracy of CoaguChek XS in Patients With Antiphospholipid Syndrome","authors":"James R. Taylor, C. Richter, Chris Lindamood, Xinyu Liu, M. Zumberg, Brad Fletcher","doi":"10.1097/POC.0000000000000149","DOIUrl":"https://doi.org/10.1097/POC.0000000000000149","url":null,"abstract":"Abstract The CoaguChek XS meter is an international normalized ratio (INR) point-of-care (POC) monitor that has been shown to provide clinically acceptable accuracy. Because of a potential interaction between antiphospholipid antibodies and the reagent used in the prothrombin time INR assay, there is uncertainty as to the reliability of using POC INR monitors in patients with antiphospholipid syndrome (APLS). The study population consisted of 41 patients on warfarin therapy for either APLS (treatment group) or any other indication (control group). All patients had their INR analyzed by the CoaguChek XS meter and a central laboratory. Overall, the mean INR difference between the CoaguChek XS and laboratory in the APLS patients was 0.6772 (P < 0.0001). In APLS patients, when the laboratory INR was less than 2.0, 2.0 to 3.0, 3.1 to 4.0, or greater than 4.0, the CoaguChek XS differed by averages of 0.0636 (P = 0.4111), 0.6903 (P < 0.0001), 1.1417 (P < 0.0001), and 0.9333 (P = 0.0848), respectively. In the control group the overall mean difference was 0.5456 (P < 0.0001). For laboratory INR values of less than 2.0, 2.0 to 3.0, 3.1 to 4.0, and greater than 4.0, the mean differences from the CoaguChek XS were 0.3000 (P = 0.0003), 0.4444 (P < 0.0001), 1.0444 (P = 0.0002), and 1.3500 (P = 0.0236). Our data do support the manufacturer recommendation of comparing laboratory and CoaguChek XS meter INRs in APLS patients because in a subset of patients the 2 methods produced acceptable results, and POC monitoring might be used.","PeriodicalId":20262,"journal":{"name":"Point of Care: The Journal of Near-Patient Testing & Technology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2017-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78869704","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 5

A Multicenter Evaluation of the Quality Management Practices for Point-of-Care Testing in Nigeria 多中心评价的质量管理实践的护理点测试在尼日利亚

Point of Care: The Journal of Near-Patient Testing & Technology Pub Date : 2017-12-01 DOI: 10.1097/POC.0000000000000152

I. Nnakenyi, C. Onyenekwu, L. Imoh, N. Ntuen, I. Mohammed, C. Nlemadim

{"title":"A Multicenter Evaluation of the Quality Management Practices for Point-of-Care Testing in Nigeria","authors":"I. Nnakenyi, C. Onyenekwu, L. Imoh, N. Ntuen, I. Mohammed, C. Nlemadim","doi":"10.1097/POC.0000000000000152","DOIUrl":"https://doi.org/10.1097/POC.0000000000000152","url":null,"abstract":"Introduction The need for timely patient management has led to the proliferation of point-of-care testing (POCT) within health care facilities. However, POCT is often implemented without supervision by laboratory personnel, which raises concern about the quality of its results. The aim of this study was to determine the quality management practices for POCT in several Nigerian tertiary hospitals. Materials and Method This was a descriptive study of 61 POCT sites at 5 tertiary hospitals across Nigeria. Research laboratories and self-monitoring POCT were excluded. Data were collected using interviewer-administered questionnaires, as well as visual inspection of records and facilities. Results were presented as counts and percentages. Results The predominant POCT was the glucometer (65%). Cost of testing was majorly 0 to 500 naira (<2 US dollars; 78%). Point-of-care testing sites were majorly operated by physicians 40%, and only 26% of the sites had documentation of training on the POCT before use. Method validation was not performed in 81% of the sites. Internal quality control and external quality assessment were performed at 26% and 10% of the sites, respectively. There was no traceability of results on the device to the patients tested at 78% of the sites. Troubleshooting a faulty device was performed by nonlaboratorians at 77% of the sites. Most sites did not involve the laboratory in device procurement (74%), validation (77%), maintenance (78%), troubleshooting (64%), or monitoring the accuracy of the results (74%). None of the hospitals had a POCT committee. Discussion The practice of quality management for POCT in tertiary hospitals was poor because of inadequately trained operators and noninvolvement of the laboratory. Laboratory staff should provide guidance and a framework for POCT implementation to ensure quality results and patient safety.","PeriodicalId":20262,"journal":{"name":"Point of Care: The Journal of Near-Patient Testing & Technology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2017-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81874057","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 3

A Novel Approach to Assess Performance of Glucometer: Error Grid Analysis 一种评估血糖仪性能的新方法:误差网格分析

Point of Care: The Journal of Near-Patient Testing & Technology Pub Date : 2017-12-01 DOI: 10.1097/POC.0000000000000150

Vandana Kumavat, M. Rojekar, Jayesh Panot, Arati Adhe-Rojekar

{"title":"A Novel Approach to Assess Performance of Glucometer: Error Grid Analysis","authors":"Vandana Kumavat, M. Rojekar, Jayesh Panot, Arati Adhe-Rojekar","doi":"10.1097/POC.0000000000000150","DOIUrl":"https://doi.org/10.1097/POC.0000000000000150","url":null,"abstract":"Abstract Glucose meters are excellent tools for self-monitoring of blood glucose especially in the circumstances where continuous monitoring is mandatory and at decision-making levels. Tight glycemic control protocols are important for preventing ill effects of fluctuating glucose levels. As technology advances, glucometers are getting better in terms of quality of results. The purpose here is to study the quality of glucose meter results in terms of clinical outcomes. The study was conducted in a tertiary care referral hospital. A total of 125 patients were recruited from pediatric wards. Bland-Altman plot, Parke error grid, and surveillance error grid analysis were used for comparing the results of the glucose meters with a standard laboratory method. It was found that there was a significant difference between the results of the 2 methods. Although usually minimal, the glucose meter results deviated from the results of the standard laboratory method. This will affect overall patient care especially in emergency conditions. Sometimes, the risk may be so high that the patient may be mislabeled as hypoglycemic when they actually are hyperglycemic and vice versa. This study is the first of its kind because no similar studies have been reported in the pediatric population. For effective use of glucose meters, the devices should give as accurate results as possible. Results should not only be accurate but also precise, without which critical errors may be possible. We recommend that for any glucose meter there should be regular calibration so that agreement with the reference laboratory method is maintained and effective medical decisions are possible.","PeriodicalId":20262,"journal":{"name":"Point of Care: The Journal of Near-Patient Testing & Technology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2017-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88271295","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Direct-to-Consumer Genetic Testing in the Personalized Medicine Era 个性化医疗时代的直接面向消费者的基因检测

Point of Care: The Journal of Near-Patient Testing & Technology Pub Date : 2017-09-01 DOI: 10.1097/POC.0000000000000146

L. Baudhuin

引用次数: 0

Direct-to-Consumer Testing: A New Paradigm for Point-of-Care Testing 直接面向消费者的测试:护理点测试的新范例

Point of Care: The Journal of Near-Patient Testing & Technology Pub Date : 2017-09-01 DOI: 10.1097/POC.0000000000000137

N. Tolan

引用次数: 3