PielPub Date : 2026-06-01Epub Date: 2026-03-24DOI: 10.1016/j.piel.2025.12.007
Antonieta Salas Ladrón de Guevara , Diego Méndez Villanueva , Montserrat Carmen Cendoya Ferrada
{"title":"Disruptores endocrinos: relevancia en dermatología y cuidado de la piel","authors":"Antonieta Salas Ladrón de Guevara , Diego Méndez Villanueva , Montserrat Carmen Cendoya Ferrada","doi":"10.1016/j.piel.2025.12.007","DOIUrl":"10.1016/j.piel.2025.12.007","url":null,"abstract":"<div><div>Endocrine disruptors (EDs) are natural or synthetic substances capable of altering hormonal function and producing adverse health effects. Their presence in cosmetics and personal care products represents a challenge for dermatology, as the skin acts not only as a barrier but also as an entryand target organ. Exposure occurs mainly through the use of sunscreens, makeup, deodorants, and shampoos, as well as from environmental pollution and occupational contact. Among the most common EDs in dermatology are parabens, phthalates, bisphenol A, triclosan, and benzophenones. Their mechanisms include hormone mimicry, receptor blockade, interference with hormone synthesis and transport, activation of the aryl hydrocarbon receptor, and transgenerational epigenetic effects. In dermatology, they are associated with contact dermatitis, acne, atopic dermatitis, pigmentation disorders and skin aging. Recognizing potential EDs and understanding their mechanisms of action are key to preventing systemic and cutaneous diseases. Dermatologists are encouraged to promote ED-free products, prefer mineral sunscreens, and educate patients about the responsible use of cosmetics to reduce cumulative risks.</div></div>","PeriodicalId":20182,"journal":{"name":"Piel","volume":"41 6","pages":"Pages 515-520"},"PeriodicalIF":0.0,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148202363","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
PielPub Date : 2026-06-01Epub Date: 2026-03-19DOI: 10.1016/j.piel.2026.01.005
Ana Lilia Ojeda Muñoz, Valerie Dafne Alcántara Ramírez, Salvador Alonso Gutíerrez Ávila, Diana Valeria Guerrero Hernández
{"title":"Hidradenitis supurativa: tratamiento con agentes biológicos y moléculas pequeñas","authors":"Ana Lilia Ojeda Muñoz, Valerie Dafne Alcántara Ramírez, Salvador Alonso Gutíerrez Ávila, Diana Valeria Guerrero Hernández","doi":"10.1016/j.piel.2026.01.005","DOIUrl":"10.1016/j.piel.2026.01.005","url":null,"abstract":"<div><div>Hidradenitis suppurativa (HS) is a chronic, recurrent inflammatory disease involving a suppurative and healing disorder of the sebaceous follicles. Although its specific pathogenesis remains unclear, it is believed that follicular hyperkeratosis and the inflammatory response play an important role. Immunological processes and cytokines such as IL-1, IL-18, and IP-10 may also be involved.</div><div>The initial symptoms include painful abscesses that may resolve within a week or form subcutaneous plaques. In chronic phases, comedones and scars that obstruct glands are observed, worsening the condition and causing intense pain, foul odor, and movement limitation due to deforming scars.</div><div>A narrative literature review was conducted in Medline, Google Scholar, SciELO, and Cochrane Library from January 1, 2014, to October 1, 2024, using the keywords “hidradenitis,” “hidradenitis suppurativa,” “systemic treatment,” “treatment,” “therapy,” “biologics”, “small molecules”.</div><div>Effective management of hidradenitis suppurativa (HS) requires a multifactorial approach that combines medical, surgical, and patient education strategies. In cases of moderate to severe HS, biologic and small molecule therapies are the most effective strategies, offering multiple treatment options, some extensively studied and others with recent or inconclusive research. Therefore, understanding the available advanced therapy options and current clinical trials allows physicians to choose the most appropriate treatment.</div></div>","PeriodicalId":20182,"journal":{"name":"Piel","volume":"41 6","pages":"Pages 529-538"},"PeriodicalIF":0.0,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148202365","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
PielPub Date : 2026-06-01Epub Date: 2026-06-09DOI: 10.1016/j.piel.2026.03.004
Luis Ángel Zamarro Díaz, Marina de la Puente Alonso, José Antonio Avilés Izquierdo
{"title":"Dermatoscopia frágil como la porcelana. Diagnóstico y comentario","authors":"Luis Ángel Zamarro Díaz, Marina de la Puente Alonso, José Antonio Avilés Izquierdo","doi":"10.1016/j.piel.2026.03.004","DOIUrl":"10.1016/j.piel.2026.03.004","url":null,"abstract":"","PeriodicalId":20182,"journal":{"name":"Piel","volume":"41 6","pages":"Pages 552-553"},"PeriodicalIF":0.0,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148202411","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
PielPub Date : 2026-06-01Epub Date: 2026-04-10DOI: 10.1016/j.piel.2025.12.015
Luis Ángel Zamarro Díaz, Marina de la Puente Alonso, José Antonio Avilés Izquierdo
{"title":"Dermatoscopia frágil como la porcelana","authors":"Luis Ángel Zamarro Díaz, Marina de la Puente Alonso, José Antonio Avilés Izquierdo","doi":"10.1016/j.piel.2025.12.015","DOIUrl":"10.1016/j.piel.2025.12.015","url":null,"abstract":"","PeriodicalId":20182,"journal":{"name":"Piel","volume":"41 6","pages":"Pages 548-549"},"PeriodicalIF":0.0,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148202369","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
PielPub Date : 2026-05-01Epub Date: 2026-01-19DOI: 10.1016/j.piel.2025.10.004
Andrea Urrego Vásquez , Laura Pérez Serna , Luz Edith Pérez Trejos
{"title":"Seguridad y complicaciones del uso de ácido hialurónico en la rinoplastia no quirúrgica","authors":"Andrea Urrego Vásquez , Laura Pérez Serna , Luz Edith Pérez Trejos","doi":"10.1016/j.piel.2025.10.004","DOIUrl":"10.1016/j.piel.2025.10.004","url":null,"abstract":"","PeriodicalId":20182,"journal":{"name":"Piel","volume":"41 5","pages":"Pages 455-458"},"PeriodicalIF":0.0,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147827544","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}