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Therapeutic Effect of Resveratrol and Gamma-GlutamylCysteine in Azathioprine Drug-Induced Hepatotoxicity 白藜芦醇和γ -谷氨酰半胱氨酸治疗硫唑嘌呤药物性肝毒性的疗效
Pharmacophore Pub Date : 2023-01-01 DOI: 10.51847/fzp0igmxlo
Huda Sultan Almutairi, Manal Abdulbari Tashkandi, Jehad Mustafa Yousef
{"title":"Therapeutic Effect of Resveratrol and Gamma-GlutamylCysteine in Azathioprine Drug-Induced Hepatotoxicity","authors":"Huda Sultan Almutairi, Manal Abdulbari Tashkandi, Jehad Mustafa Yousef","doi":"10.51847/fzp0igmxlo","DOIUrl":"https://doi.org/10.51847/fzp0igmxlo","url":null,"abstract":"","PeriodicalId":20012,"journal":{"name":"Pharmacophore","volume":"94 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135959807","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Prevalence of Obesity in Female Schoolchildren, Risk Factors, and Relation to Lifestylein Tabuk, Saudi Arabia 沙特阿拉伯Tabuk地区女学童肥胖患病率、危险因素及与生活方式的关系
IF 0.5
Pharmacophore Pub Date : 2023-01-01 DOI: 10.51847/15zxkypumr
N. Gad, Mohamed Elbatanony, H. Mirghani, M. Sheikh, M. Alamri, Abdallah Ali, Hisham Alshadfan, S. Begum, Yara Elbatanony, Abeer Alotaibi, Moneera Alkhrisi, Layan AlHarby
{"title":"Prevalence of Obesity in Female Schoolchildren, Risk Factors, and Relation to Lifestylein Tabuk, Saudi Arabia","authors":"N. Gad, Mohamed Elbatanony, H. Mirghani, M. Sheikh, M. Alamri, Abdallah Ali, Hisham Alshadfan, S. Begum, Yara Elbatanony, Abeer Alotaibi, Moneera Alkhrisi, Layan AlHarby","doi":"10.51847/15zxkypumr","DOIUrl":"https://doi.org/10.51847/15zxkypumr","url":null,"abstract":"","PeriodicalId":20012,"journal":{"name":"Pharmacophore","volume":"1 1","pages":""},"PeriodicalIF":0.5,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70809871","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Formulation, Evaluation, and Validation of Microspheres of Cyclophosphamide for Topical Delivery 局部给药环磷酰胺微球的配方、评价和验证
IF 0.5
Pharmacophore Pub Date : 2023-01-01 DOI: 10.51847/e4gvuon96z
M. Sahu, Neha Dubey, R. Pandey, S. Shukla, B. Gidwani
{"title":"Formulation, Evaluation, and Validation of Microspheres of Cyclophosphamide for Topical Delivery","authors":"M. Sahu, Neha Dubey, R. Pandey, S. Shukla, B. Gidwani","doi":"10.51847/e4gvuon96z","DOIUrl":"https://doi.org/10.51847/e4gvuon96z","url":null,"abstract":"","PeriodicalId":20012,"journal":{"name":"Pharmacophore","volume":"1 1","pages":""},"PeriodicalIF":0.5,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70819034","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Neural Network–Based Search for COX-2 Active Ligands from Coxib-like and Similar Compounds 基于神经网络的coxib类及类似化合物中COX-2活性配体的搜索
IF 0.5
Pharmacophore Pub Date : 2023-01-01 DOI: 10.51847/ezwhoceeec
L. T. Billones, A. Gonzaga
{"title":"Neural Network–Based Search for COX-2 Active Ligands from Coxib-like and Similar Compounds","authors":"L. T. Billones, A. Gonzaga","doi":"10.51847/ezwhoceeec","DOIUrl":"https://doi.org/10.51847/ezwhoceeec","url":null,"abstract":"Received: 09 Feb 2023 Received in revised form: 10 May 2023 Accepted: 14 May 2023 Available online: 28 Jun 2023","PeriodicalId":20012,"journal":{"name":"Pharmacophore","volume":"1 1","pages":""},"PeriodicalIF":0.5,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70820196","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Health-Related Knowledge Attitude Practice and Quality of Life Among Diabetic Hypertensive Patients in Eastern Nepal 尼泊尔东部地区糖尿病高血压患者健康相关知识、态度、行为与生活质量
IF 0.5
Pharmacophore Pub Date : 2023-01-01 DOI: 10.51847/kvpxg6nvx5
Pratiksha Gautam, P. Dahal, Deevan Paul, K. Alam
{"title":"Health-Related Knowledge Attitude Practice and Quality of Life Among Diabetic Hypertensive Patients in Eastern Nepal","authors":"Pratiksha Gautam, P. Dahal, Deevan Paul, K. Alam","doi":"10.51847/kvpxg6nvx5","DOIUrl":"https://doi.org/10.51847/kvpxg6nvx5","url":null,"abstract":"","PeriodicalId":20012,"journal":{"name":"Pharmacophore","volume":"1 1","pages":""},"PeriodicalIF":0.5,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70826888","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Study of Basic Emotions in the General Population Using the Likert Scale 用李克特量表研究普通人群的基本情绪
IF 0.5
Pharmacophore Pub Date : 2023-01-01 DOI: 10.51847/tjyoah1vwm
N. Nicoară, D. Varga, Florica Voiță-Mekereș, Larisa-Bianca Galea-Holhos, Gineta Andreescu, Lavinia Costas
{"title":"Study of Basic Emotions in the General Population Using the Likert Scale","authors":"N. Nicoară, D. Varga, Florica Voiță-Mekereș, Larisa-Bianca Galea-Holhos, Gineta Andreescu, Lavinia Costas","doi":"10.51847/tjyoah1vwm","DOIUrl":"https://doi.org/10.51847/tjyoah1vwm","url":null,"abstract":"Received: 25 Apr 2023 Received in revised form: 14 Jul 2023 Accepted: 20 Jul 2023 Available online: 28 Aug 2023","PeriodicalId":20012,"journal":{"name":"Pharmacophore","volume":"1 1","pages":""},"PeriodicalIF":0.5,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70834608","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Effects of Dimethyl Sulfoxide on Hippocampal Activity in a Rotenone-Induced Rat Model of Parkinson’s Disease 二甲亚砜对鱼藤酮诱导的帕金森病大鼠模型海马活动的影响
Pharmacophore Pub Date : 2023-01-01 DOI: 10.51847/vafvsv35cl
Lilit Darbinyan, Karen Simonyan, Larisa Manukyan, Lilia Hambardzumyan
{"title":"Effects of Dimethyl Sulfoxide on Hippocampal Activity in a Rotenone-Induced Rat Model of Parkinson’s Disease","authors":"Lilit Darbinyan, Karen Simonyan, Larisa Manukyan, Lilia Hambardzumyan","doi":"10.51847/vafvsv35cl","DOIUrl":"https://doi.org/10.51847/vafvsv35cl","url":null,"abstract":"Parkinson's disease (PD) is the second most common age-related neurodegenerative disease worldwide. The goal of this study was to examine the effects of dimethyl sulfoxide (DMSO) in a rat model of Parkinson's disease caused by rotenone. Due to its capacity to increase the penetration of potential water-insoluble drugs into the central nervous system, DMSO has been widely used in preclinical and clinical studies. Background and evoked spike activities were recorded in the hippocampus of rats administered DMSO (1 ml/kg i.p. for 3 weeks). We showed that pyramidal cells and Nissl bodies in the hippocampal CA1 and CA3 areas of rats administered rotenone dramatically improved after DMSO treatment. Rotenone enhanced TP and induced a milder TD effect, while DMSO also enhanced TP but induced a stronger TD effect. The analysis revealed inhibitory effects in the hippocampus in response to high-frequency stimulation (HFS; 100 Hz for 1 s) of the ipsilateral entorhinal cortex.","PeriodicalId":20012,"journal":{"name":"Pharmacophore","volume":"5 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135262471","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Financial Evaluation and Pattern of Antibiotic Consumption in Intensive Care Units of a University Hospital. 某大学医院重症监护病房抗生素消费财务评价与模式
Pharmacophore Pub Date : 2023-01-01 DOI: 10.51847/ymw2symqir
Viviana Hodoșan, Dana Carmen Zaha, Lucia Georgeta Daina, Alina Manuela Tîrb, Lavinia Florica Mărcuț, Aurel George Mohan, Petru Cotrău, Cristian Marius Daina
{"title":"Financial Evaluation and Pattern of Antibiotic Consumption in Intensive Care Units of a University Hospital.","authors":"Viviana Hodoșan, Dana Carmen Zaha, Lucia Georgeta Daina, Alina Manuela Tîrb, Lavinia Florica Mărcuț, Aurel George Mohan, Petru Cotrău, Cristian Marius Daina","doi":"10.51847/ymw2symqir","DOIUrl":"https://doi.org/10.51847/ymw2symqir","url":null,"abstract":"","PeriodicalId":20012,"journal":{"name":"Pharmacophore","volume":"132 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135312479","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Community Pharmacies Services and Preparedness During Covid-19 Pandemic in Saudi Arabia: A Cross-Sectional Study 沙特阿拉伯Covid-19大流行期间的社区药房服务和准备:一项横断面研究
Pharmacophore Pub Date : 2023-01-01 DOI: 10.51847/iyoaj9kc0c
Abdulaziz Alhossan, Noha Al Aloola, Manar Basoodan, Munirah Alkathiri, Razan Alshahrani, Wael Mansy, Thamer A Almangour
{"title":"Community Pharmacies Services and Preparedness During Covid-19 Pandemic in Saudi Arabia: A Cross-Sectional Study","authors":"Abdulaziz Alhossan, Noha Al Aloola, Manar Basoodan, Munirah Alkathiri, Razan Alshahrani, Wael Mansy, Thamer A Almangour","doi":"10.51847/iyoaj9kc0c","DOIUrl":"https://doi.org/10.51847/iyoaj9kc0c","url":null,"abstract":"","PeriodicalId":20012,"journal":{"name":"Pharmacophore","volume":"15 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135401100","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Flavonoids of Capparis Cartilaginea Fruit Extract Effect on Wound Healing in Human Prostate Cancer Cell Line 软骨葡萄果提取物黄酮类化合物对人前列腺癌细胞伤口愈合的影响
IF 0.5
Pharmacophore Pub Date : 2022-01-01 DOI: 10.51847/0q8tpkdopw
H. S. Sonbol, Maram Maram Bakr Hosawi
{"title":"Flavonoids of Capparis Cartilaginea Fruit Extract Effect on Wound Healing in Human Prostate Cancer Cell Line","authors":"H. S. Sonbol, Maram Maram Bakr Hosawi","doi":"10.51847/0q8tpkdopw","DOIUrl":"https://doi.org/10.51847/0q8tpkdopw","url":null,"abstract":"","PeriodicalId":20012,"journal":{"name":"Pharmacophore","volume":"1 1","pages":""},"PeriodicalIF":0.5,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70809724","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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