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Esterase responsive release of anti-cancer agents from conjugated lipid nanocarrier and the regulatory considerations 共轭脂质纳米载体释放抗癌剂的酯酶反应及监管考虑因素
IF 1.8
Pharmaceutical patent analyst Pub Date : 2024-07-16 DOI: 10.1080/20468954.2024.2347796
Priya Varpe, Ramesh Joga, Gayatri Aglave, Pavan Y Vasu, Sravani Yerram, Kiran Kumar Bellapu, Saurabh Srivastava, Sandeep Kumar
{"title":"Esterase responsive release of anti-cancer agents from conjugated lipid nanocarrier and the regulatory considerations","authors":"Priya Varpe, Ramesh Joga, Gayatri Aglave, Pavan Y Vasu, Sravani Yerram, Kiran Kumar Bellapu, Saurabh Srivastava, Sandeep Kumar","doi":"10.1080/20468954.2024.2347796","DOIUrl":"https://doi.org/10.1080/20468954.2024.2347796","url":null,"abstract":"","PeriodicalId":20011,"journal":{"name":"Pharmaceutical patent analyst","volume":null,"pages":null},"PeriodicalIF":1.8,"publicationDate":"2024-07-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141643320","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Liraglutide innovations: a comprehensive review of patents (2014–2024) 利拉鲁肽创新：专利综合评述（2014-2024 年）
IF 1.8
Pharmaceutical patent analyst Pub Date : 2024-07-16 DOI: 10.1080/20468954.2024.2366693
Ajay Pandey, Amit Kumar Goyal
{"title":"Liraglutide innovations: a comprehensive review of patents (2014–2024)","authors":"Ajay Pandey, Amit Kumar Goyal","doi":"10.1080/20468954.2024.2366693","DOIUrl":"https://doi.org/10.1080/20468954.2024.2366693","url":null,"abstract":"","PeriodicalId":20011,"journal":{"name":"Pharmaceutical patent analyst","volume":null,"pages":null},"PeriodicalIF":1.8,"publicationDate":"2024-07-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141640618","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Catalyzing innovation in cancer drug discovery through artificial intelligence, machine learning and patency 通过人工智能、机器学习和专利催化癌症药物研发创新
IF 1.3
Pharmaceutical patent analyst Pub Date : 2024-05-21 DOI: 10.1080/20468954.2024.2347798
M. Okereke, Samson Ayorinde Oni, Zainab Ashimiyu-Abdusalam, Owolade Adedoyin John-Joy, Charles Diovu, Adeniyi Ayinde Abdulwahab, Adebayo Israel Jesutimilehin, Nwosu Ebube Clinton, Ibeh John Somtochukwu, Omojuyigbe Jeremiah Oluwamayowa, Kawthar Olatunde Olaitan, Damilola Bodun Samuel
{"title":"Catalyzing innovation in cancer drug discovery through artificial intelligence, machine learning and patency","authors":"M. Okereke, Samson Ayorinde Oni, Zainab Ashimiyu-Abdusalam, Owolade Adedoyin John-Joy, Charles Diovu, Adeniyi Ayinde Abdulwahab, Adebayo Israel Jesutimilehin, Nwosu Ebube Clinton, Ibeh John Somtochukwu, Omojuyigbe Jeremiah Oluwamayowa, Kawthar Olatunde Olaitan, Damilola Bodun Samuel","doi":"10.1080/20468954.2024.2347798","DOIUrl":"https://doi.org/10.1080/20468954.2024.2347798","url":null,"abstract":"","PeriodicalId":20011,"journal":{"name":"Pharmaceutical patent analyst","volume":null,"pages":null},"PeriodicalIF":1.3,"publicationDate":"2024-05-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141117234","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Patent highlights August-September 2023. 2023 年 8 月至 9 月的专利要点。
IF 1.3
Pharmaceutical patent analyst Pub Date : 2024-03-18 DOI: 10.4155/ppa-2023-0039
Hermann Am Mucke
{"title":"Patent highlights August-September 2023.","authors":"Hermann Am Mucke","doi":"10.4155/ppa-2023-0039","DOIUrl":"https://doi.org/10.4155/ppa-2023-0039","url":null,"abstract":"<p><p>A snapshot of noteworthy recent developments in the patent literature of relevance to pharmaceutical and medical research and development.</p>","PeriodicalId":20011,"journal":{"name":"Pharmaceutical patent analyst","volume":null,"pages":null},"PeriodicalIF":1.3,"publicationDate":"2024-03-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140144000","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Patent Highlights June-July 2023. 2023 年 6 月至 7 月的专利亮点。
IF 1.3
Pharmaceutical patent analyst Pub Date : 2024-03-18 DOI: 10.4155/ppa-2023-0035
Hermann Am Mucke
{"title":"Patent Highlights June-July 2023.","authors":"Hermann Am Mucke","doi":"10.4155/ppa-2023-0035","DOIUrl":"https://doi.org/10.4155/ppa-2023-0035","url":null,"abstract":"<p><p>A snapshot of noteworthy recent developments in the patent literature of relevance to pharmaceutical and medical research and development.</p>","PeriodicalId":20011,"journal":{"name":"Pharmaceutical patent analyst","volume":null,"pages":null},"PeriodicalIF":1.3,"publicationDate":"2024-03-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140144001","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Proposed supplementary protection certificate legislation for medicinal products. 拟议的医药产品补充保护证书立法。
IF 1.3
Pharmaceutical patent analyst Pub Date : 2023-11-01 Epub Date: 2024-01-10 DOI: 10.4155/ppa-2023-0031
Olivia J Creemer, Stephen Garner
{"title":"Proposed supplementary protection certificate legislation for medicinal products.","authors":"Olivia J Creemer, Stephen Garner","doi":"10.4155/ppa-2023-0031","DOIUrl":"10.4155/ppa-2023-0031","url":null,"abstract":"","PeriodicalId":20011,"journal":{"name":"Pharmaceutical patent analyst","volume":null,"pages":null},"PeriodicalIF":1.3,"publicationDate":"2023-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139404018","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Patent Highlights April-May 2023. 2023 年 4 月至 5 月的专利亮点。
IF 1.3
Pharmaceutical patent analyst Pub Date : 2023-11-01 Epub Date: 2024-01-10 DOI: 10.4155/ppa-2023-0028
Hermann Am Mucke
{"title":"Patent Highlights April-May 2023.","authors":"Hermann Am Mucke","doi":"10.4155/ppa-2023-0028","DOIUrl":"10.4155/ppa-2023-0028","url":null,"abstract":"<p><p>A snapshot of noteworthy recent developments in the patent literature of relevance to pharmaceutical and medical research and development.</p>","PeriodicalId":20011,"journal":{"name":"Pharmaceutical patent analyst","volume":null,"pages":null},"PeriodicalIF":1.3,"publicationDate":"2023-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139404016","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Progression and expansion of quinoline as bioactive moiety: a patent review. 作为生物活性分子的喹啉的进步与发展：专利回顾。
IF 1.3
Pharmaceutical patent analyst Pub Date : 2023-11-01 Epub Date: 2024-01-31 DOI: 10.4155/ppa-2023-0025
Yash Chauhan, Kumari Neha, Sharad Wakode, Mohd Shahfaiz, Ramesh B Bodla, Kalicharan Sharma
{"title":"Progression and expansion of quinoline as bioactive moiety: a patent review.","authors":"Yash Chauhan, Kumari Neha, Sharad Wakode, Mohd Shahfaiz, Ramesh B Bodla, Kalicharan Sharma","doi":"10.4155/ppa-2023-0025","DOIUrl":"10.4155/ppa-2023-0025","url":null,"abstract":"<p><p>Quinoline inhibitors are appealing medicinal products for a range of illnesses and problems. It is bicyclic heterocyclic scaffold has been intensively employed in pharmacological research and is well known for its wide range of biological purposes. Biological activities exhibited by quinoline derivatives, such as anti-inflammatory properties, antioxidant, antimicrobial, anti-tubercular, antidiabetic, anti-malarial and others are covered in detail in this review. The IC<sub>50</sub> of patented inhibitors might range from nm to μM range, based on the experiments used. It presents an outline of patents file between 2002 and 2023 concerning to biological activities by quinoline derivatives. As a result, it is critical to develop additional chemical quinoline core alterations for novel chemical compounds and enhanced pharmacological impacts.</p>","PeriodicalId":20011,"journal":{"name":"Pharmaceutical patent analyst","volume":null,"pages":null},"PeriodicalIF":1.3,"publicationDate":"2023-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139642691","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Patenting trends by Mexican pharmaceutical companies. 墨西哥制药公司的专利申请趋势。
IF 1.3
Pharmaceutical patent analyst Pub Date : 2023-11-01 Epub Date: 2024-01-10 DOI: 10.4155/ppa-2023-0029
Luis Villafaña-Diaz, Juan C Perez-Garcia, Diana Barron-Villaverde, Martin Perez-Santos
{"title":"Patenting trends by Mexican pharmaceutical companies.","authors":"Luis Villafaña-Diaz, Juan C Perez-Garcia, Diana Barron-Villaverde, Martin Perez-Santos","doi":"10.4155/ppa-2023-0029","DOIUrl":"10.4155/ppa-2023-0029","url":null,"abstract":"<p><p><b>Aim:</b> the activity of patent claims by Mexican pharmaceutical companies is unknown. <b>Objective:</b> analyse the trend in patents of Mexican pharmaceutical companies. <b>Method:</b> a search for patents was carried out in the patent database of the Mexican Institute of Industrial Property, using the list of Mexican pharmaceutical companies belonging to the Mexican Association of Pharmaceutical Research Industries, and the codes A61K, A61P and C07 of the International Patent Classification. <b>Results:</b> the leading companies in patent applications were Liomont, Senosiain and RIMSA; however, Mexican pharmaceutical companies claim very few patents, only 266 patent applications in the period 2000-2020, with a technological factor with a value of zero, and a commercial factor of little value. <b>Conclusion:</b> Mexican pharmaceutical companies lack a robust patent system, without growth, and with a low percentage of patents with high commercial value.</p>","PeriodicalId":20011,"journal":{"name":"Pharmaceutical patent analyst","volume":null,"pages":null},"PeriodicalIF":1.3,"publicationDate":"2023-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139404017","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Lipid-based mesoporous silica nanoparticles: a paradigm shift in management of pancreatic cancer. 基于脂质的介孔二氧化硅纳米粒子：胰腺癌治疗模式的转变。
IF 1.3
Pharmaceutical patent analyst Pub Date : 2023-11-01 Epub Date: 2024-01-12 DOI: 10.4155/ppa-2023-0024
Kiran Kumar Bellapu, Ramesh Joga, Bharthi R Kannan, Sravani Yerram, Priya Varpe, Tejaswini Mergu, Pavan Y Vasu, Saurabh Srivastava, Sandeep Kumar
{"title":"Lipid-based mesoporous silica nanoparticles: a paradigm shift in management of pancreatic cancer.","authors":"Kiran Kumar Bellapu, Ramesh Joga, Bharthi R Kannan, Sravani Yerram, Priya Varpe, Tejaswini Mergu, Pavan Y Vasu, Saurabh Srivastava, Sandeep Kumar","doi":"10.4155/ppa-2023-0024","DOIUrl":"10.4155/ppa-2023-0024","url":null,"abstract":"<p><p>Pancreatic adenocarcinoma, a devastating disease, has the worst cancer prognosis in humans. It often develops resistance to common chemotherapy medications, such as gemcitabine, taxol and 5-fluorouracil. The dense stroma limits therapeutic efficacy in treating this disease. Low or limited drug loading capacity is another problem with current chemotherapeutic agents. There is a need to develop novel approaches to overcome these issues. Hence, an innovative approach has been proposed to co-deliver both hydrophilic (Gemcitabine) and hydrophobic (Paclitaxel) drugs in a single carrier using lipid bilayer-mesoporous silica nanoparticles (LB-MSNP). MSNPs offer effective drug delivery due to their superior bioavailability and physicochemical properties. Further, in order to achieve clinical translation and regulatory approval, toxicity and biodegradability of MSNPs must be resolved.</p>","PeriodicalId":20011,"journal":{"name":"Pharmaceutical patent analyst","volume":null,"pages":null},"PeriodicalIF":1.3,"publicationDate":"2023-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139425271","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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