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Patent highlights August-September 2023. 2023 年 8 月至 9 月的专利要点。
IF 1.3
Pharmaceutical patent analyst Pub Date : 2024-03-18 DOI: 10.4155/ppa-2023-0039
Hermann Am Mucke
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引用次数: 0
Patent Highlights June-July 2023. 2023 年 6 月至 7 月的专利亮点。
IF 1.3
Pharmaceutical patent analyst Pub Date : 2024-03-18 DOI: 10.4155/ppa-2023-0035
Hermann Am Mucke
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引用次数: 0
Insights to the emerging potential of glucokinase activators as antidiabetic agent. 洞察葡萄糖激酶激活剂作为抗糖尿病药物的新兴潜力。
IF 1.8
Pharmaceutical patent analyst Pub Date : 2024-01-01 Epub Date: 2024-09-11 DOI: 10.1080/20468954.2024.2389762
Anuradha Mehra, Shubham Kumar, Anu Mittal, Ruchi Kohli, Amit Mittal
{"title":"Insights to the emerging potential of glucokinase activators as antidiabetic agent.","authors":"Anuradha Mehra, Shubham Kumar, Anu Mittal, Ruchi Kohli, Amit Mittal","doi":"10.1080/20468954.2024.2389762","DOIUrl":"10.1080/20468954.2024.2389762","url":null,"abstract":"<p><p>The glucokinase enzyme (belongs to the hexokinase family) is present in liver cells and β-cells of the pancreas. Glucokinase acts as a catalyst in the conversion of glucose-6-phosphate from glucose which is rate-limiting step in glucose metabolism. Glucokinase becomes malfunctional or remains inactivated in diabetes. Glucokinase activators are compounds that bind at the allosteric site of the glucokinase enzyme and activate it. This article highlights the patent and recent research papers history with possible SAR from year 2014-2023. The data comprises the discussion of novel chemotypes (GKAs) that are being targeted for drug development and entered into clinical trials. GK activators have attracted massive interest since successful results have been reported from clinical trials data.</p>","PeriodicalId":20011,"journal":{"name":"Pharmaceutical patent analyst","volume":"13 1-3","pages":"53-71"},"PeriodicalIF":1.8,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11449038/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142351906","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
3D-printed immediate release solid dosage forms: a patent evaluation of US11622940B2. 三维打印速释固体制剂：US11622940B2 的专利评估。
IF 1.8
Pharmaceutical patent analyst Pub Date : 2024-01-01 Epub Date: 2024-09-04 DOI: 10.1080/20468954.2024.2389774
Akshay Sharma, Ritu Rathi, Sanchay Sharma, Tanikan Sangnim, Kampanart Huanbutta, Inderbir Singh
{"title":"3D-printed immediate release solid dosage forms: a patent evaluation of US11622940B2.","authors":"Akshay Sharma, Ritu Rathi, Sanchay Sharma, Tanikan Sangnim, Kampanart Huanbutta, Inderbir Singh","doi":"10.1080/20468954.2024.2389774","DOIUrl":"10.1080/20468954.2024.2389774","url":null,"abstract":"<p><p>Three-dimensional (3D) printing is one of the most flexible technologies for preparing tablets, offering controlled drug release profiles. The current patent describes the preparation of immediate-release 3D-printed tablets of hydrochlorothiazide to improve disintegration and dissolution profile. The patent involves the preparation of drug-loaded filament via hot-melt extrusion and utilizing the same filaments for printing 3D-printed tablets using fused deposition modeling. The tablets were printed with different shapes and sizes by incorporating channels within the tablet spaces, termed as gaplets. The introduction of channels within the tablet design improves the disintegration and dissolution profile of the drug significantly. The morphological characteristic of 3D-printed tablets was studied by using scanning electron microscopy and revealed the presence of gaplets in the tablets.</p>","PeriodicalId":20011,"journal":{"name":"Pharmaceutical patent analyst","volume":"13 1-3","pages":"45-51"},"PeriodicalIF":1.8,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11449147/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142351905","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Patent Highlights June-July 2023. 2023 年 6 月至 7 月的专利亮点。
IF 1.8
Pharmaceutical patent analyst Pub Date : 2024-01-01 Epub Date: 2024-03-18 DOI: 10.4155/ppa-2023-0035
Hermann Am Mucke
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引用次数: 0
Patent highlights August-September 2023. 2023 年 8 月至 9 月的专利要点。
IF 1.8
Pharmaceutical patent analyst Pub Date : 2024-01-01 Epub Date: 2024-03-18 DOI: 10.4155/ppa-2023-0039
Hermann Am Mucke
{"title":"Patent highlights August-September 2023.","authors":"Hermann Am Mucke","doi":"10.4155/ppa-2023-0039","DOIUrl":"https://doi.org/10.4155/ppa-2023-0039","url":null,"abstract":"<p><p>A snapshot of noteworthy recent developments in the patent literature of relevance to pharmaceutical and medical research and development.</p>","PeriodicalId":20011,"journal":{"name":"Pharmaceutical patent analyst","volume":"13 1-3","pages":"15-22"},"PeriodicalIF":1.8,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142351907","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Patent highlights October-November 2023. 2023 年 10 月至 11 月的专利要点。
IF 1.8
Pharmaceutical patent analyst Pub Date : 2024-01-01 Epub Date: 2024-09-04 DOI: 10.1080/20468954.2024.2389765
Hermann Am Mucke
{"title":"Patent highlights October-November 2023.","authors":"Hermann Am Mucke","doi":"10.1080/20468954.2024.2389765","DOIUrl":"https://doi.org/10.1080/20468954.2024.2389765","url":null,"abstract":"<p><p>A snapshot of noteworthy recent developments in the patent literature of relevance to pharmaceutical and medical research and development.</p>","PeriodicalId":20011,"journal":{"name":"Pharmaceutical patent analyst","volume":"13 1-3","pages":"23-29"},"PeriodicalIF":1.8,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142351909","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Proposed supplementary protection certificate legislation for medicinal products. 拟议的医药产品补充保护证书立法。
IF 1.3
Pharmaceutical patent analyst Pub Date : 2023-11-01 Epub Date: 2024-01-10 DOI: 10.4155/ppa-2023-0031
Olivia J Creemer, Stephen Garner
{"title":"Proposed supplementary protection certificate legislation for medicinal products.","authors":"Olivia J Creemer, Stephen Garner","doi":"10.4155/ppa-2023-0031","DOIUrl":"10.4155/ppa-2023-0031","url":null,"abstract":"","PeriodicalId":20011,"journal":{"name":"Pharmaceutical patent analyst","volume":" ","pages":"249-252"},"PeriodicalIF":1.3,"publicationDate":"2023-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139404018","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Patent Highlights April-May 2023. 2023 年 4 月至 5 月的专利亮点。
IF 1.3
Pharmaceutical patent analyst Pub Date : 2023-11-01 Epub Date: 2024-01-10 DOI: 10.4155/ppa-2023-0028
Hermann Am Mucke
{"title":"Patent Highlights April-May 2023.","authors":"Hermann Am Mucke","doi":"10.4155/ppa-2023-0028","DOIUrl":"10.4155/ppa-2023-0028","url":null,"abstract":"<p><p>A snapshot of noteworthy recent developments in the patent literature of relevance to pharmaceutical and medical research and development.</p>","PeriodicalId":20011,"journal":{"name":"Pharmaceutical patent analyst","volume":" ","pages":"253-259"},"PeriodicalIF":1.3,"publicationDate":"2023-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139404016","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Progression and expansion of quinoline as bioactive moiety: a patent review. 作为生物活性分子的喹啉的进步与发展：专利回顾。
IF 1.3
Pharmaceutical patent analyst Pub Date : 2023-11-01 Epub Date: 2024-01-31 DOI: 10.4155/ppa-2023-0025
Yash Chauhan, Kumari Neha, Sharad Wakode, Mohd Shahfaiz, Ramesh B Bodla, Kalicharan Sharma
{"title":"Progression and expansion of quinoline as bioactive moiety: a patent review.","authors":"Yash Chauhan, Kumari Neha, Sharad Wakode, Mohd Shahfaiz, Ramesh B Bodla, Kalicharan Sharma","doi":"10.4155/ppa-2023-0025","DOIUrl":"10.4155/ppa-2023-0025","url":null,"abstract":"<p><p>Quinoline inhibitors are appealing medicinal products for a range of illnesses and problems. It is bicyclic heterocyclic scaffold has been intensively employed in pharmacological research and is well known for its wide range of biological purposes. Biological activities exhibited by quinoline derivatives, such as anti-inflammatory properties, antioxidant, antimicrobial, anti-tubercular, antidiabetic, anti-malarial and others are covered in detail in this review. The IC<sub>50</sub> of patented inhibitors might range from nm to μM range, based on the experiments used. It presents an outline of patents file between 2002 and 2023 concerning to biological activities by quinoline derivatives. As a result, it is critical to develop additional chemical quinoline core alterations for novel chemical compounds and enhanced pharmacological impacts.</p>","PeriodicalId":20011,"journal":{"name":"Pharmaceutical patent analyst","volume":" ","pages":"287-314"},"PeriodicalIF":1.3,"publicationDate":"2023-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139642691","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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