{"title":"Eli Lilly Joins ImmunoGen’s List of Big Pharma Collaborators","authors":"Heather Cartwright","doi":"10.3833/pdr.v2012i1.1648","DOIUrl":"https://doi.org/10.3833/pdr.v2012i1.1648","url":null,"abstract":"Eli Lilly has gained rights to use ImmunoGen’s maytansinoid targeted antibody payload (TAP) technology to develop a specified number of antibody-drug conjugates for the potential treatment of cancer. ImmunoGen will receive US$20 M upfront and could receive up to US$200 M in milestone payments for each licence taken as well as royalties on sales of any resulting products. With this deal, Eli Lilly has joined ImmunoGen’s list of TAP partners that includes Amgen, Bayer Healthcare, Roche, Novartis and Sanofi.","PeriodicalId":19951,"journal":{"name":"Pharmadeals Review","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2012-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89161478","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"InterMune Divests Declining Actimmune® to Focus on Esbriet®","authors":"Heather Cartwright","doi":"10.3833/pdr.v2012i5.1746","DOIUrl":"https://doi.org/10.3833/pdr.v2012i5.1746","url":null,"abstract":"InterMune has agreed to sell the rights to Actimmune® (interferon gamma-1b), which is approved for the treatment of chronic granulomatous disease and severe, malignant osteopetrosis, to Vidara Therapeutics International for US$55 M in cash plus royalties over 2 years. The proceeds from the transaction will help InterMune to invest in the registration and commercialisation of its idiopathic pulmonary fibrosis drug Esbriet® (pirfenidone) in Europe and elsewhere.","PeriodicalId":19951,"journal":{"name":"Pharmadeals Review","volume":"6 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2012-05-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89536788","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Agilent Technologies Agrees to Acquire Dako for US$2.2 B in its Largest Deal to Date","authors":"Heather Cartwright","doi":"10.3833/PDR.V2012I5.1744","DOIUrl":"https://doi.org/10.3833/PDR.V2012I5.1744","url":null,"abstract":"Agilent Technologies has agreed to buy the Danish cancer diagnostics company Dako, which is currently owned by the Swedish private equity group EQT Partners, for US$2.2 B. The acquisition, which represents the largest deal in Agilent’s history, is the company’s latest attempt to expand its life sciences business and will complement its existing diagnostics portfolio.","PeriodicalId":19951,"journal":{"name":"Pharmadeals Review","volume":"2 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2012-05-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86075697","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"GSK to Acquire Full Control of its Proteomics Partner Cellzome","authors":"Heather Cartwright","doi":"10.3833/PDR.V2012I5.1743","DOIUrl":"https://doi.org/10.3833/PDR.V2012I5.1743","url":null,"abstract":"GlaxoSmithKline (GSK) has agreed to acquire the 80.02% of its proteomics research partner Cellzome that it does not already own for £61 M (US$98 M) in cash. The acquisition will expand GSK’s existing drug discovery platform and add to its capacity to characterise drug targets. Simultaneously, the two parties intend to create a spin-off company, which would hold the rights to certain Cellzome assets and activities that GSK does not wish to progress.","PeriodicalId":19951,"journal":{"name":"Pharmadeals Review","volume":"4 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2012-05-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88391403","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Abbott to Acquire Global Rights to Action Pharma’s Phase II Acute Kidney Injury Drug","authors":"Heather Cartwright","doi":"10.3833/PDR.V2012I5.1742","DOIUrl":"https://doi.org/10.3833/PDR.V2012I5.1742","url":null,"abstract":"Abbott is to acquire worldwide development and commercialisation rights to Action Pharma’s AP214, an alpha-MSH (melanocyte-stimulating hormone) peptide derivative in Phase IIb development for the prevention of acute kidney injury associated with major cardiac surgery, for a one-time cash payment of US$110 M. Zealand Pharma, from which Action licensed the SIP® (structure induced probe) peptide modification technology that has been used in the development of AP214, also stands to benefit from the deal.","PeriodicalId":19951,"journal":{"name":"Pharmadeals Review","volume":"50 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2012-05-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74937878","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"GSK Divests its Final Tranche of Non-Core OTC Brands to Aspen Pharmacare","authors":"Heather Cartwright","doi":"10.3833/pdr.v2012i4.1731","DOIUrl":"https://doi.org/10.3833/pdr.v2012i4.1731","url":null,"abstract":"GlaxoSmithKline has agreed to sell a portfolio of international OTC brands, excluding the troubled anti-obesity drug alli® (orlistat, 60 mg), to South Africa’s Aspen Pharmacare for £164 M (US$263 M). The divested brands generated sales of approximately £60 M (US$94 M) in 2011. The acquisition will drive growth for Aspen in Latin America and Southeast Asia.","PeriodicalId":19951,"journal":{"name":"Pharmadeals Review","volume":"36 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2012-04-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84354104","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Sanofi Augments its Biosurgery Unit with Pluromed Acquisition","authors":"Heather Cartwright","doi":"10.3833/pdr.v2012i3.1705","DOIUrl":"https://doi.org/10.3833/pdr.v2012i3.1705","url":null,"abstract":"Sanofi has agreed to buy the US medical device company Pluromed in order to strengthen the biosurgery portfolio it gained via its takeover of Genzyme in 2011. With the acquisition, Sanofi will gain Pluromed’s biocompatible reverse thermosensitive polymer technology, Rapid Transition Polymers™, and LeGoo® gel, which was approved by the US FDA in September 2011 and which provides temporary blood vessel occlusion during surgery","PeriodicalId":19951,"journal":{"name":"Pharmadeals Review","volume":"51 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2012-03-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82381905","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Shire Bolsters its Haematology Business with US$325 M FerroKin BioSciences Acquisition","authors":"Heather Cartwright","doi":"10.3833/PDR.V2012I3.1702","DOIUrl":"https://doi.org/10.3833/PDR.V2012I3.1702","url":null,"abstract":"Shire has moved to strengthen its haematology franchise by agreeing to acquire FerroKin BioSciences for up to US$325 M. With the acquisition, Shire will gain FerroKin’s iron chelator FBS0701, which is in Phase II development for the treatment of iron overload due to chronic blood transfusions. Shire will pay US$100 M upfront in cash and up to US$225 M in potential clinical development, regulatory and commercial milestones related to the drug, which could be launched as early as 2016.","PeriodicalId":19951,"journal":{"name":"Pharmadeals Review","volume":"6 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2012-03-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90608387","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Mersana Therapeutics Raises Profile with Antibody-Drug Conjugate Collaboration with Endo","authors":"Heather Cartwright","doi":"10.3833/PDR.V2012I3.1700","DOIUrl":"https://doi.org/10.3833/PDR.V2012I3.1700","url":null,"abstract":"Mersana Therapeutics has formed a collaboration with Endo Pharmaceuticals to develop next-generation antibody-drug conjugates (ADCs) against a single, undisclosed cancer target. Mersana will combine its Fleximer® conjugation technology with anticancer antibodies discovered by Endo to produce Fleximer-ADC candidates for development, manufacturing and commercialisation by Endo. With this deal, Mersana has emerged as a competitor of Seattle Genetics and ImmunoGen in the development of ADCs.","PeriodicalId":19951,"journal":{"name":"Pharmadeals Review","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2012-03-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74571773","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Daiichi Sankyo and GSK to Establish Vaccines Joint Venture in Japan","authors":"Heather Cartwright","doi":"10.3833/PDR.V2012I3.1699","DOIUrl":"https://doi.org/10.3833/PDR.V2012I3.1699","url":null,"abstract":"Daiichi Sankyo and GlaxoSmithKline have agreed to form a 50-50 joint venture for the development and distribution of vaccines in Japan. The joint venture, which will be named Japan Vaccine and which will commence business in July 2012 with an initial capitalisation of ¥100 M (US$1.2 M), will inherit development and commercialisation rights to prophylactic vaccines from both parent companies. Its business will later be expanded as new vaccines from the pipeline are approved.","PeriodicalId":19951,"journal":{"name":"Pharmadeals Review","volume":"94 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2012-03-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75240415","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}