Periodica Polytechnica Chemical Engineering最新文献_第8页

Development of Dry Walnut Shell Edible Film Plasticized with Glycerol and/or Sorbitol and Incorporated with Aloe Vera Gel and Lemon Essential Oil 用甘油和/或山梨糖醇增塑并掺入芦荟凝胶和柠檬精油的干核桃壳食用膜的研制

IF 1.3 4区工程技术

Periodica Polytechnica Chemical Engineering Pub Date : 2023-03-27 DOI: 10.3311/ppch.21511

Berika Girgin, N. Tugrul

{"title":"Development of Dry Walnut Shell Edible Film Plasticized with Glycerol and/or Sorbitol and Incorporated with Aloe Vera Gel and Lemon Essential Oil","authors":"Berika Girgin, N. Tugrul","doi":"10.3311/ppch.21511","DOIUrl":"https://doi.org/10.3311/ppch.21511","url":null,"abstract":"Edible packaging films produced from biomaterials are environmentally friendly, promising alternatives against synthetic plastics films. The aim of this study was to produce a low-cost edible film from waste dry walnut shell by casting method. Effects of the plasticizer type and concentration, lemon essential oil (LEO) and aloe vera gel (AVG) addition on edible films properties were investigated. Produced edible films characterization analysis were realized by Scanning Electron Microscopy (SEM) and Fourier Transform Infrared Spectroscopy (FTIR). Moisture content, water vapor transmission rate (WVTR), water solubility, swelling index, thicknesses and color parameters of the produced edible films were investigated. Moisture content of the films was decreased between 23.3–50.6% after LEO and AVG addition, except the moisture content of the film plasticized with 20% sorbitol was increased by 518%. WVTR of the films were increased between 8.7–72.3% after LEO and AVG addition due to the hydrophobic character of LEO. Glycerol plasticized edible films water solubility were decreased between 27.3–75.9%, sorbitol plasticized edible films water solubility were increased between 237.5–100.8% with LEO and AVG incorporation. The swelling index of C1 was reduced by 51.5%, C2 was reduced by 62.4%, C4 was reduced by 36.1%. The swelling index of the C3 was increased by 10.5%, C5 was increased by 21.5%. LEO and AVG addition increased to the film thickness maximum 79.2%. Total color changes (ΔE) of glycerol plasticized films were higher than sorbitol plasticized film. The edible film produced can be used in food packaging due to the appropriate physical and barrier properties.","PeriodicalId":19922,"journal":{"name":"Periodica Polytechnica Chemical Engineering","volume":null,"pages":null},"PeriodicalIF":1.3,"publicationDate":"2023-03-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90723712","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Robustness Study of a Tensile Modulus Prediction Model for Semicrystalline Polymers 半结晶聚合物拉伸模量预测模型的鲁棒性研究

IF 1.3 4区工程技术

Periodica Polytechnica Chemical Engineering Pub Date : 2023-03-16 DOI: 10.3311/ppch.20991

Ali Zarbali, Balázs Pinke, A. Menyhárd

{"title":"Robustness Study of a Tensile Modulus Prediction Model for Semicrystalline Polymers","authors":"Ali Zarbali, Balázs Pinke, A. Menyhárd","doi":"10.3311/ppch.20991","DOIUrl":"https://doi.org/10.3311/ppch.20991","url":null,"abstract":"This work presents a robustness study of a previously developed empirical model that links Young's modulus to two key parameters of crystalline structure; crystallinity and lamellae thickness. The reliability of this modulus prediction model was tested by using different calorimeters and different polypropylene grades as well. Small samples were fabricated from injection-molded bars from different locations of the specimens in order to check the effect of structural inhomogeneity originated by the dynamic processing conditions. In addition, the standard deviation and consequently the accuracy of the prediction was tested by repeated calorimetric measurements. The crystalline structure and melting characteristics were measured by differential scanning calorimetry (DSC). The tensile properties of studied specimens were evaluated by standardized tensile tests. Although, the accuracy and reliability of the prediction model is dependent on the instrument used for thermal analysis, reasonably good agreement was found between the predicted and measured values in most cases. However, we may note that only well-calibrated calorimeters are suitable for reliable prediction of the modulus.","PeriodicalId":19922,"journal":{"name":"Periodica Polytechnica Chemical Engineering","volume":null,"pages":null},"PeriodicalIF":1.3,"publicationDate":"2023-03-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83321786","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Fabrication, Characterization and Permeation Studies of Ionically Cross-linked Chitosan/Kaolin Composite Membranes 离子交联壳聚糖/高岭土复合膜的制备、表征及渗透研究

IF 1.3 4区工程技术

Periodica Polytechnica Chemical Engineering Pub Date : 2023-03-09 DOI: 10.3311/ppch.21253

S. B. Rekik, S. Gassara, J. Bouaziz, S. Baklouti, A. Deratani

{"title":"Fabrication, Characterization and Permeation Studies of Ionically Cross-linked Chitosan/Kaolin Composite Membranes","authors":"S. B. Rekik, S. Gassara, J. Bouaziz, S. Baklouti, A. Deratani","doi":"10.3311/ppch.21253","DOIUrl":"https://doi.org/10.3311/ppch.21253","url":null,"abstract":"This paper presents the successful preparation of porous membranes based on chitosan with enhanced mechanical, thermal and chemical properties applicable in water treatment field. Herein, chitosan/kaolin composite membranes with a cross-linking agent and a porogen were prepared using the solvent casting method. The characterization of the as-fabricated membranes indicated that the combined effect of kaolin as reinforcing agent, polyethylene glycol as pore former and citric acid as cross-linker in a chitosan matrix showed a significant influence on the membrane properties. The results indicated that the incorporation of a hydrophilic porogenic reagent into the collodion in addition to providing a porous morphology makes it possible to obtain a more hydrophilic membrane, and thus induces an increase in the pure water permeability. The cross-linked membranes exhibited an improved water resistance, better thermal and mechanical properties as compared to neat chitosan films. The cross-linked membranes had a mean pore size of 50 nm falling in the range of ultrafiltration. Their functional properties were determined in terms of pure water filtration and molecular weight cut-off tests.","PeriodicalId":19922,"journal":{"name":"Periodica Polytechnica Chemical Engineering","volume":null,"pages":null},"PeriodicalIF":1.3,"publicationDate":"2023-03-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80123095","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Developing a Targeting Approach for Syngas Generation from Natural Gas 开发天然气制合成气的目标方法

IF 1.3 4区工程技术

Periodica Polytechnica Chemical Engineering Pub Date : 2023-02-06 DOI: 10.3311/ppch.21115

B. Patel, Bahizire Martin Mukeru

引用次数: 0

Effect of Fe Addition on Anaerobic Digestion Process in Treating Vinasse: Experimental and Kinetic Studies 添加铁对处理酒渣厌氧消化过程的影响:实验与动力学研究

IF 1.3 4区工程技术

Periodica Polytechnica Chemical Engineering Pub Date : 2023-01-27 DOI: 10.3311/ppch.20611

I. Syaichurrozi, S. Sarto, W. B. Sediawan, M. Hidayat

{"title":"Effect of Fe Addition on Anaerobic Digestion Process in Treating Vinasse: Experimental and Kinetic Studies","authors":"I. Syaichurrozi, S. Sarto, W. B. Sediawan, M. Hidayat","doi":"10.3311/ppch.20611","DOIUrl":"https://doi.org/10.3311/ppch.20611","url":null,"abstract":"Vinasse is a continuously resulting waste by a bioethanol industry with a high chemical oxygen demand (COD) concentration and a large volume. Anaerobic digestion (AD) is the best method to treat vinasse because it converts COD to biogas, so the biogas can support the Indonesia's primary energy need. The goal of this study was to study the effect of Fe concentration on the AD process in treating the vinasse. The Fe concentration was varied to 0.06, 0.29, 0.64, 0.99 g/L. The results showed that increasing the Fe concentration from 0.06 to 0.29 g/L intensified the biogas yield by 360% (from 10.8 to 49.6 mL/g COD). However, further increasing the Fe concentration to 0.99 g/L decreased the biogas yield by 37.8% (from 10.8 to 6.7 mL/g COD). The Fe significantly affected the methane formation stage, but not the acid formation stage. A mechanistic model was built and successfully applied to predict the AD process. Based on the simulation results, Fe concentration of 0.29 g/L resulted in the highest values of YVFA/X2 (yield of volatile fatty acids (VFAs) consumption per biomass of X2 ), μm,2 (specific growth rate for X2 ), fCH4 (composition of methane in biogas) and the lowest values of Ks,VFA (affinity coefficient in VFAs consumption), kd2 (death rate constant for X2 ), kVFA (consumption rate of VFAs for maintenance). The addition of Fe until 0.29 g/L was recommended to increase the quantity and quality (methane content reached 53.4%) of biogas production.","PeriodicalId":19922,"journal":{"name":"Periodica Polytechnica Chemical Engineering","volume":null,"pages":null},"PeriodicalIF":1.3,"publicationDate":"2023-01-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82701056","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

Recent List of Cyclodextrin-Containing Drug Products 含环糊精的药品最新清单

IF 1.3 4区工程技术

Periodica Polytechnica Chemical Engineering Pub Date : 2023-01-16 DOI: 10.3311/ppch.21222

I. Puskás, L. Szente, Levente Szőcs, É. Fenyvesi

引用次数: 9

Application of MIA-QSAR in Designing New Protein P38 MAP Kinase Compounds Using a Genetic Algorithm MIA-QSAR在遗传算法设计新的蛋白P38 MAP激酶化合物中的应用

IF 1.3 4区工程技术

Periodica Polytechnica Chemical Engineering Pub Date : 2023-01-11 DOI: 10.3311/ppch.20852

Mithra Mirshafiei, A. Niazi, A. Yazdanipour

{"title":"Application of MIA-QSAR in Designing New Protein P38 MAP Kinase Compounds Using a Genetic Algorithm","authors":"Mithra Mirshafiei, A. Niazi, A. Yazdanipour","doi":"10.3311/ppch.20852","DOIUrl":"https://doi.org/10.3311/ppch.20852","url":null,"abstract":"Multivariate image analysis quantitative structure-activity relationship (MIA-QSAR) study aims to obtain information from a descriptor set, which are image pixels of two-dimensional molecule structures. In the QSAR study of protein P38 mitogen-activated protein (MAP) kinase compounds, the genetic algorithm application for pixel selection and image processing is investigated. There is a quantitative relationship between the structure and the pIC50 based on the information obtained. (The pIC50 is the negative logarithm of the half-maximal inhibitory concentration ( IC50 ), so pIC50 = −log IC50 .) Protein P38 MAP kinase inhibitors are used in the treatment of malignant tumors. The development of a model to predict the pIC50 of these compounds was performed in this study. To accomplish this, the molecules were first plotted and fixed in the same coordinates in ChemSketch. Then, the images were processed in the MATLAB program. Partial least squares (PLS) model, orthogonal signal correction partial least squares (OSC-PLS) model, and genetic algorithm partial least squares (GA-PLS) model methods are used to generate quantitative models, and pIC50 prediction is performed. The GA-PLS model has the highest predictive power for a series of statistical parameters such as root mean square error of prediction (RMSEP) and relative standard errors of prediction (RSEP). Finally, the molecular junction (docking) was done for predicted molecules in quantitative structure activity relationship (QSAR) with an appropriate receptor and acceptable results were obtained. These results are good and proper for the prediction of compounds with better properties.","PeriodicalId":19922,"journal":{"name":"Periodica Polytechnica Chemical Engineering","volume":null,"pages":null},"PeriodicalIF":1.3,"publicationDate":"2023-01-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88848213","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Antioxidant and Antimicrobial Agents from Avocado (Persea americana) Seed Extract Encapsulated in Gum Arabic through Spray Drying Method 喷雾干燥法从阿拉伯胶包封的鳄梨(Persea americana)种子提取物中提取抗氧化剂和抗菌剂

IF 1.3 4区工程技术

Periodica Polytechnica Chemical Engineering Pub Date : 2023-01-11 DOI: 10.3311/ppch.20698

D. B. Kautsar, M. F. Rois, Nurul Faizah, W. Widiyastuti, T. Nurtono, H. Setyawan

{"title":"Antioxidant and Antimicrobial Agents from Avocado (Persea americana) Seed Extract Encapsulated in Gum Arabic through Spray Drying Method","authors":"D. B. Kautsar, M. F. Rois, Nurul Faizah, W. Widiyastuti, T. Nurtono, H. Setyawan","doi":"10.3311/ppch.20698","DOIUrl":"https://doi.org/10.3311/ppch.20698","url":null,"abstract":"In this work, the objective is to utilize avocado seed extract as a cheap alternative source of active compounds and was successfully encapsulated using gum arabic by spray drying as an antioxidant and antimicrobial agent. First, the active compounds were extracted from avocado seed using solvent n-hexane and followed by solvent separation using rotary vacuum evaporator. Next, gum arabic as the encapsulation agent was added to avocado seed extract to form an emulsion, then spray-dried with drying air at a temperature of 140 °C. The mass ratio of avocado seed was varied at extract: gum arabic of 5:5, 5:10, 5:15, and 5:20. Then, the particle morphology, yield, moisture content, encapsulation efficiency, loading capacity, chemical groups, antioxidant activity, and antibacterial ability were analyzed to investigate the performance of the encapsulation particles. Among the ranges studied, the extract–gum arabic with a mass ratio of 5:10 exhibited the best properties of yield powder, loading capacity, and encapsulation efficiency at 49.78%, 3.43%, and 7.33%, respectively. The encapsulated particles have smooth surface, crackless, lower indentation, and a single-core encapsulation structure with an average diameter of 4.60 μm. Besides, the stability of antioxidant activity decreased by 2.36%, from 94.82% to 92.46% for four weeks of storage. They also performed antimicrobial activity against E. coli and S. aureus, which were maintained after seven days. Meanwhile for avocado seed extract only, the unencapsulated stability of antioxidant activity has continually decrease from 91.58% to 84.05% and performed no antimicrobial activity against E. coli after seven days.","PeriodicalId":19922,"journal":{"name":"Periodica Polytechnica Chemical Engineering","volume":null,"pages":null},"PeriodicalIF":1.3,"publicationDate":"2023-01-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76673468","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 3

Stereoselective Synthesis of Novel (±)-trans-Dihydronarciclasine Analogues: Preparation of a Pivotal Intermediate Containing Two Methoxy Substituents 新型(±)-反式二氢精氨酸类似物的立体选择性合成:含两个甲氧基取代基的关键中间体的制备

IF 1.3 4区工程技术

Periodica Polytechnica Chemical Engineering Pub Date : 2023-01-09 DOI: 10.3311/ppch.20438

Balázs Lévai, Gábor Varró, A. Simon, L. Hegedűs, I. Kádas

引用次数: 1

The Effect of Surfactants and pH Modifying Agents on the Dissolution and Permeation of Pimobendan 表面活性剂和pH改性剂对比莫苯丹溶解和渗透的影响

IF 1.3 4区工程技术

Periodica Polytechnica Chemical Engineering Pub Date : 2023-01-09 DOI: 10.3311/ppch.20970

Petra Tőzsér, Luca L. Kovács, Szabina Kádár, Dóra Csicsák, P. Sóti, Gergely Völgyi, B. Sinkó, Z. Nagy, Enikő Borbás

{"title":"The Effect of Surfactants and pH Modifying Agents on the Dissolution and Permeation of Pimobendan","authors":"Petra Tőzsér, Luca L. Kovács, Szabina Kádár, Dóra Csicsák, P. Sóti, Gergely Völgyi, B. Sinkó, Z. Nagy, Enikő Borbás","doi":"10.3311/ppch.20970","DOIUrl":"https://doi.org/10.3311/ppch.20970","url":null,"abstract":"Solubility and permeability are key parameters for establishing in vitro-in vivo correlation for poorly water-soluble active pharmaceutical ingredients (APIs). Recent studies demonstrate that not only solubility, but also effective permeability of the API may change due to the addition of solubilizing agents, and there is a certain mathematical relation between these physicochemical parameters. The aim of this study was to show the importance of early screening of solubility and permeability in presence of additives in order to achieve the expected bioavailability of the API. In this work, the effect of surfactants and microenvironmental pH modifiers were in focus, and pimobendan was chosen as model drug.In the case of pH modifiers, the equilibrium solubility of the API increased, while the permeability decreased significantly. No negative effect was observed for two surfactants at low additive levels, but these two additives also exhibited a slightly negative effect on permeability when used at higher concentrations. In the simultaneous dissolution-permeation studies the surfactants-containing formulation was found to have slightly higher flux than the pH-modifier-containing one. It can be due to the phenomenon that the dissolution of the active substance can be enhanced by these surfactants without any significant permeability reducing effect.The results obtained from the present study clearly demonstrate the importance of studying drug-additive interactions in every step of formulation development and based on these, the selection of the appropriate quality and quantity of additives. In addition, the results also underline the significance of performing simultaneous dissolution-permeation studies to predict bioavailability.","PeriodicalId":19922,"journal":{"name":"Periodica Polytechnica Chemical Engineering","volume":null,"pages":null},"PeriodicalIF":1.3,"publicationDate":"2023-01-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89297323","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0