PHARMACY: Jurnal Farmasi Indonesia (Pharmaceutical Journal of Indonesia)最新文献

Analisis Cost of Illness pada Pasien Diabetes Mellitus Dengan Terapi Glimepiride-Metformin Rawat Jalan Peserta BPJS di Puskesmas Ketapang II Kota Sampit 梅尔提乌斯糖尿病患者的病理成本分析与糖尿病患者门诊胶质- metformin门诊治疗

PHARMACY: Jurnal Farmasi Indonesia (Pharmaceutical Journal of Indonesia) Pub Date : 2023-12-01 DOI: 10.21776/ub.pji.2023.008.02.5

Nur Ghina Apriliana, Fakultas Ilmu Kesehatan, Universitas Muhammadiyah Malang, Malang, Indonesia, Liza Pristianty, Ika Ratna Hidayati, Fakultas Farmasi, Universitas Airlangga, Surabaya, Indonesia, Fakultas Ilmu Kesehatan, Universitas Muhammadiyah Malang, Malang, Indonesia

{"title":"Analisis Cost of Illness pada Pasien Diabetes Mellitus Dengan Terapi Glimepiride-Metformin Rawat Jalan Peserta BPJS di Puskesmas Ketapang II Kota Sampit","authors":"Nur Ghina Apriliana, Fakultas Ilmu Kesehatan, Universitas Muhammadiyah Malang, Malang, Indonesia, Liza Pristianty, Ika Ratna Hidayati, Fakultas Farmasi, Universitas Airlangga, Surabaya, Indonesia, Fakultas Ilmu Kesehatan, Universitas Muhammadiyah Malang, Malang, Indonesia","doi":"10.21776/ub.pji.2023.008.02.5","DOIUrl":"https://doi.org/10.21776/ub.pji.2023.008.02.5","url":null,"abstract":"Diabetes mellitus is a chronic disease that affects the costs incurred by patients during illness. The financingissuedfor the treatment of diabetes mellitus diseases can be measured using Cost of Illness analysis. Research objectivestofind out the total cost of treatment of diabetes mellitus patients BPJS participants with Glymepiride-Metformintherapy for one year. The method this study used a non-probability sampling technique with an accidental sampling method. This research conducted at Ketapang II Health Center with sample total 45 people. The instrument usedastructured interview which was previously tested for validity. Data were analyzed using Microsoft Excel. Result andconclusion, the estimate total cost of treatment of diabetes mellitus with outpatient glimepiride-metformin therapyofIndonesia Health Insurance participants at Ketapang II Health Center in Sampit city for one year is Rp.623.760-Rp.4.475.520. The direct medical cost per patient is Rp.143.760 - Rp.2.787.120. Non-medical direct cost is Rp.0-Rp.188.400. Indirect cost is Rp.480.000 - Rp.1.500.000. High cost are more expensive but the frequencyof visitsand patient compliance are orderly so that the therapeutic effect achieved is good, while the lowcost is cheaper butthe frequency of patient visits and patient compliance are not orderly so that the therapeutic effect achievedislessgood and not maximal.","PeriodicalId":19897,"journal":{"name":"PHARMACY: Jurnal Farmasi Indonesia (Pharmaceutical Journal of Indonesia)","volume":"8 2","pages":"143-148"},"PeriodicalIF":0.0,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://pji.ub.ac.id/index.php/pji/article/download/289/193","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147917709","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Cost Analysis of Telepharmacy Programs for Diabetes Mellitus Patients at Pharmacy 药房为糖尿病患者提供远程药学计划的成本分析

PHARMACY: Jurnal Farmasi Indonesia (Pharmaceutical Journal of Indonesia) Pub Date : 2023-09-12 DOI: 10.30595/pharmacy.v0i0.13765

Indwi Sekar Nagrini, Didik Setiawan, Galar Sigit Prasuma, Muhammad Ahsan Iftikhar Baig

引用次数: 0

Aktivitas Antibiofilm Ekstrak dan Fraksi-Fraksi Bunga Telang (Clitoria ternatea L.) terhadap Staphylococcus aureus 泰兰花提取物和馏分（Clitoria ternatea L.）对金黄色葡萄球菌的抗生物膜活性

PHARMACY: Jurnal Farmasi Indonesia (Pharmaceutical Journal of Indonesia) Pub Date : 2023-08-08 DOI: 10.30595/pharmacy.v0i0.14437

Emma Jayanti Besan, Ismi Rahmawati, Opstaria Saptarini

引用次数: 0

Watermelon (Citrullus lanatus (Thunb.) Matsum. & Nakai) Exocarp Extract Effectivity Against Blood Uric Acid Levels in Male Mice (Mus musculus) 西瓜（Citrullus lanatus（Thunb.

PHARMACY: Jurnal Farmasi Indonesia (Pharmaceutical Journal of Indonesia) Pub Date : 2023-08-08 DOI: 10.30595/pharmacy.v0i0.14471

Nisa Najwa Rokhmah, Sri Intan Giyanita, E. M. Effendi, Eka Herlina

{"title":"Watermelon (Citrullus lanatus (Thunb.) Matsum. & Nakai) Exocarp Extract Effectivity Against Blood Uric Acid Levels in Male Mice (Mus musculus)","authors":"Nisa Najwa Rokhmah, Sri Intan Giyanita, E. M. Effendi, Eka Herlina","doi":"10.30595/pharmacy.v0i0.14471","DOIUrl":"https://doi.org/10.30595/pharmacy.v0i0.14471","url":null,"abstract":"Uric acid is the product of the body from foods that contain high purines. Watermelon (Citrullus lanatus (Thunb.) Matsum. & Nakai) exocarp contains active compounds such as lycopene and flavonoids, which can inhibit the formation of free radicals and inhibit xanthine oxidation. This study aims to determine the activity of watermelon exocarp extract on uric acid levels in male mice. Twenty-five mice were divided into five experimental groups, with each treatment consisting of five replicate male mice. Treatment groups consisted of a solvent control (CMC Na 0.5%), a positive control (Allopurinol 0.26 mg/20gBB), dose I (Watermelon exocarp extract 50 mg/kgBB), dose II (Watermelon exocarp extract 100 mg/kgBB), dose III (Watermelon exocarp extract 200 mg/kgBB). Then the test animals were measured for uric acid levels, and each treatment was carried out with induction of chicken liver suspension 25 mg/kgBB until it showed that the mice had hyperuricemia. Mice were treated similarly to the treatment group for 15 days until their uric acid levels became normal. Blood uric acid levels were measured on days 5, 10, and 15. The results showed that all treatment doses had activity as a reduction in uric acid levels, and dose III of watermelon exocarp extract 200 mg/kgBB with a duration of 15 days was the most effective dose as a reduction in uric acid levels with a percentage reduction of 53,16 %.","PeriodicalId":19897,"journal":{"name":"PHARMACY: Jurnal Farmasi Indonesia (Pharmaceutical Journal of Indonesia)","volume":"27 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-08-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139351320","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Identifikasi Drug Related Problems pada Pasien Skizofrenia dengan Komorbid di RSJ dr. H Marzoeki Mahdi Bogor H Marzoeki Mahdi Bogor 博士，RSJ，有合并症的精神分裂症患者的药物相关问题鉴定

PHARMACY: Jurnal Farmasi Indonesia (Pharmaceutical Journal of Indonesia) Pub Date : 2023-08-08 DOI: 10.30595/pharmacy.v0i0.15486

Witri Resmiati, Wawaimuli Arozal, Dian Ratih Laksmitawati

{"title":"Identifikasi Drug Related Problems pada Pasien Skizofrenia dengan Komorbid di RSJ dr. H Marzoeki Mahdi Bogor","authors":"Witri Resmiati, Wawaimuli Arozal, Dian Ratih Laksmitawati","doi":"10.30595/pharmacy.v0i0.15486","DOIUrl":"https://doi.org/10.30595/pharmacy.v0i0.15486","url":null,"abstract":"Pada pasien skizofrenia, penyakit fisik atau komorbid merupakan salah satu penyebab yang potensial untuk mengurangi harapan hidup penderitanya. Penggunaan psikofarmaka bersamaan dengan obat untuk terapi komorbid memiliki risiko terhadap kejadian masalah terkait obat (Drug Related Problems). Identifikasi kasus masalah terkait obat(DRP) pada penelitian ini dilakukan terhadap obat yang digunakan oleh pasien yang dirawat di ruang stabilisisasi RSJ dr. H Marzoeki Mahdi Bogor selama periode Agustus – Oktober tahun 2021. Metode penelitian menggunakan disain cohortdengan pendekatan prospektif dan data dianalisis secara deskriptif. Klasifikai kejadian DRP dilakukan sesuai dengan klasifikasi PCNE versi 9.0 yang ditetapkan oleh Pharmaceutical Care Network Europe Association. Dari 125 pasien skizofrenia yang diamati, diperoleh data demografi pasien skizofrenia disertai komorbid adalah sebagian besar dengan jenis kelamin pria sebanyak 74 pasien (59.2 %), 59 pasien (47,2 %) tergolong kelompok usia 41 – 60 tahun, dan jenis penyakit penyerta tertinggi yang ditemukan adalah hipertensi berjumlah 77 pasien (61.6 %). Kasus DRP yang telah diidentifikasikan sebanyak 56 kasus DRP pada 44 pasien, dengan kasus terbanyak pada domain P2.1 yaitu efek obat yang merugikan (yang dapat terjadi) sebanyak 32 kasus (57,14%). Penyebab terjadinya DRP berkaitan dengan pemilihan obat (C1) yaitu C1.3 : Tidak ada indikasi untuk obat 15 kasus (26,79%), C1.4 : Kombinasi yang tidak tepat 7 kasus (12,50%), dan C1.7: banyak obat untuk satu indikasi 10 kasus (17,85%). Jumlah obat yang digunakan pasien, dan komorbiditas berpengaruh terhadap kasus DRP yang ditemukan pada pasien (p value< 0,05).","PeriodicalId":19897,"journal":{"name":"PHARMACY: Jurnal Farmasi Indonesia (Pharmaceutical Journal of Indonesia)","volume":"2018 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-08-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139351362","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Analisis Korelasi Pengetahuan dan Perilaku Tenaga Kefarmasian dalam Penanganan Sitostatika di Rumah Sakit Pekanbaru 北干巴鲁医院药剂人员处理细胞抑制剂的知识和行为相关性分析

PHARMACY: Jurnal Farmasi Indonesia (Pharmaceutical Journal of Indonesia) Pub Date : 2023-08-08 DOI: 10.30595/pharmacy.v0i0.9791

Ratna Sari Dewi, Desi Tri Rahmadani, Septi Muharni

引用次数: 0

Antioxidant and Anti-Propionibacterium acnes Activities of Citronella Oil and Clove Oil, and their Formulation Into Emulgel 香茅油和丁香油的抗氧化和抗丙酸杆菌活性及其在润肤露中的配制方法

PHARMACY: Jurnal Farmasi Indonesia (Pharmaceutical Journal of Indonesia) Pub Date : 2023-08-08 DOI: 10.30595/pharmacy.v0i0.12629

Nur Aji, Arum Puspitasari, Haevia Nafisah, Levina Hadi Vania Armilda

{"title":"Antioxidant and Anti-Propionibacterium acnes Activities of Citronella Oil and Clove Oil, and their Formulation Into Emulgel","authors":"Nur Aji, Arum Puspitasari, Haevia Nafisah, Levina Hadi Vania Armilda","doi":"10.30595/pharmacy.v0i0.12629","DOIUrl":"https://doi.org/10.30595/pharmacy.v0i0.12629","url":null,"abstract":"Propionibacterium acnes is a common acne-causing bacteria in adolescents and adults. The combination of citronella oil and clove oil has the potential to inhibit the growth of Propionibacterium acnes. Both essential oils are also known to have antioxidant effects. The combination of the two essential oils is expected to have better activity. The purpose of this research was to determine the activity of the Fractional Inhibitory Concentration (FIC) index against Propionibacterium acnes, antioxidant activity, and formulation in emulgel. Antibacterial assay of combination citronella oil and clove oil using the FIC index. Antioxidant assay by DPPH (2,2-diphenyl-1-picrihydrazil) method. The emulgels formulation uses Viscolam AT 100P as the base of the emulgels. The results showed that the combination of citronella and clove oil an antibacterial activity with an FIC index is 2 (indifferent), antioxidant citronella oil had an IC50 of a moderate category (185.04 µg/mL) and clove oil in a very strong category (23.48 µg/mL) so that it could be formulated in an emulgel with good characteristics. The most preferred formula in terms of color, scent, consistency, and texture is a formula with a concentration of 5% viscolam AT 100P.","PeriodicalId":19897,"journal":{"name":"PHARMACY: Jurnal Farmasi Indonesia (Pharmaceutical Journal of Indonesia)","volume":"50 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-08-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139351335","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Uji Efektivitas Sedatif-Hipnotik Ekstrak Daun Keji Beling (Strobilanthes crispa Blume) terhadap Mencit Putih Jantan 柯枝肚叶提取物对雄性白鼠的镇静催眠效果试验

PHARMACY: Jurnal Farmasi Indonesia (Pharmaceutical Journal of Indonesia) Pub Date : 2023-08-08 DOI: 10.30595/pharmacy.v0i0.14234

Gita Novelatika Friatna, Lela Lailatul Khumaisah, Devi Indah Anwar

{"title":"Uji Efektivitas Sedatif-Hipnotik Ekstrak Daun Keji Beling (Strobilanthes crispa Blume) terhadap Mencit Putih Jantan","authors":"Gita Novelatika Friatna, Lela Lailatul Khumaisah, Devi Indah Anwar","doi":"10.30595/pharmacy.v0i0.14234","DOIUrl":"https://doi.org/10.30595/pharmacy.v0i0.14234","url":null,"abstract":"Insomnia merupakan sebuah gangguan tidur yang bisa menimbulkan banyak masalah kesehatan, seperti menurunnya sistem kekebalan tubuh serta tekanan darah tinggi, sehingga perlu penanganan yang serius. Penanganan insomnia biasanya dilakukan dengan cara pemberian golongan obat sedatif-hipnotik seperti benzodiazepin dan barbiturat. Namun, golongan obat tersebut mempunyai efek samping yang berbahaya, mulai dari mual, sakit kepala ringan hingga vertigo. Penelitian tentang obat insomnia dari bahan alam telah banyak dilakukan. Salah satunya yaitu mengenai potensi keji beling (Strobilanthes crispa Blume) terhadap sedatif-hipnotik yang dilakukan secara in silico menggunakan metode molecular docking dan membuktikan bahwa kandungan d-limonen pada daun keji beling memiliki hasil yang paling baik terhadap aktivitas sedatif-hipnotik. Penelitian lanjutan ini bertujuan untuk mengetahui keefektifan ekstrak daun keji beling terhadap efek sedatif-hipnotik pada mencit. Metode yang digunakan adalah fireplace test, dengan parameter pengujian berupa lamanya waktu mencit untuk keluar dari dalam tabung yang diletakkan di atas penangas, hal ini untuk mengetahui berapa lama penurunan aktivitas gerak pada mencit. Objek penelitian sebanyak 15 ekor mencit jantan dibagi menjadi 5 kelompok yaitu, kontrol negatif (akuades), kontrol positif (diazepam 2 mg/70kgBB), perlakuan dosis 1 (200 mg/kgBB), dosis 2 (400 mg/kgBB), dan dosis 3 (600 mg/kgBB). Hasil penelitian menunjukkan bahwa rata-rata waktu mencit keluar dari tabung pada masing-masing kelompok perlakuan berturut-turut adalah 5, 120, 87, 118, dan 123 detik. Dari hasil penelitian ini, dosis III mempunyai efek sedatif-hipnotik yang lebih baik dari kontrol positif. Dari data yang didapatkan serta analisis ANOVA yang sudah dilakukan, dapat disimpulkan bahwa dosis 600 mg/kgBB memiliki efek yang lebih baik jika dibandingkan dengan kontrol positif yaitu diazepam.","PeriodicalId":19897,"journal":{"name":"PHARMACY: Jurnal Farmasi Indonesia (Pharmaceutical Journal of Indonesia)","volume":"44 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-08-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139351313","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Analisis Tingkat Kepuasan Responden Terhadap Kualitas Pemberian Informasi Obat Di UPT Puskesmas Bengkalis Kecamatan Bengkalis Provinsi Riau 廖内省本卡利斯县 UPT Puskesmas Bengkalis 的受访者对药品信息提供质量的满意度分析

PHARMACY: Jurnal Farmasi Indonesia (Pharmaceutical Journal of Indonesia) Pub Date : 2023-08-08 DOI: 10.30595/pharmacy.v0i0.9228

Fina Aryani, Mohammad Reza Firmansyah

引用次数: 0

Antigenotoxic Potential of Dayak Onion Bulb and Leaf (Eleutherine bulbosa Urb.) Ethanol Extract with Allium cepa Assay 达雅克洋葱鳞茎和叶（Eleutherine bulbosa Urb.）

PHARMACY: Jurnal Farmasi Indonesia (Pharmaceutical Journal of Indonesia) Pub Date : 2023-08-08 DOI: 10.30595/pharmacy.v0i0.12475

Husna Zuhaida, N. Etikawati, Widya Mudyantini

{"title":"Antigenotoxic Potential of Dayak Onion Bulb and Leaf (Eleutherine bulbosa Urb.) Ethanol Extract with Allium cepa Assay","authors":"Husna Zuhaida, N. Etikawati, Widya Mudyantini","doi":"10.30595/pharmacy.v0i0.12475","DOIUrl":"https://doi.org/10.30595/pharmacy.v0i0.12475","url":null,"abstract":"Dayak onion (Eleutherine bulbosa Urb.) has the potential as an antigenotoxic agent capable of counteracting the effects of damage to DNA due to ROS (Reactive Oxygen Species). The bioactive compounds in Dayak onions have antiradical scavenging activity that plays a role in counteracting free radicals so that they can improve the genotoxicity that occurs. The purpose of this study was to determine the antigenotoxic potential of the ethanol extract of Dayak onion bulb and Dayak onion leaf using the Allium cepa assay. This study used a completely randomized design with various treatments of extract concentration (0.5, 1, 5, and 10 ppm) after immersion of 3% hydrogen peroxide (H2O2) with 3 replications. Chromosome observations of shallot (Allium cepa L.) roots were carried out between 09.00-10.00 am and then the mitotic index and percentage of inhibition were determined. Data were analyzed descriptively qualitatively, quantitatively, and through the ANOVA test followed by the 5% DMRT test. The ethanolic extract of 10 ppm Dayak onion bulb showed the highest antigenotoxic activity with a mitotic index reaching 6.78% and an inhibition percentage of 92.25%. The antigenotoxic activity of the ethanolic extract of Dayak onion bulb was higher than the ethanolic extract of Dayak onion leaf. These results are related to the antiradical scavenging activity of the ethanolic extract of Dayak onion bulb which is also higher than the ethanolic extract of Dayak onion leaf.","PeriodicalId":19897,"journal":{"name":"PHARMACY: Jurnal Farmasi Indonesia (Pharmaceutical Journal of Indonesia)","volume":"98 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-08-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139351323","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0