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连翘及其相关方剂治疗急性化脓性扁桃体炎的研究进展 连翘及其相关方剂治疗急性化脓性扁桃体炎的研究进展
药学与临床研究 Pub Date : 2025-12-27 DOI: 10.65140/ebcm202502.11
嘉欣 梁, 鑫 刘, 鹏 张
{"title":"连翘及其相关方剂治疗急性化脓性扁桃体炎的研究进展","authors":"嘉欣 梁, 鑫 刘, 鹏 张","doi":"10.65140/ebcm202502.11","DOIUrl":"https://doi.org/10.65140/ebcm202502.11","url":null,"abstract":"急性化脓性扁桃体炎是临床常见的上呼吸道感染性疾病，以咽痛、扁桃体红肿化脓、发热为主要特征，多发于儿童及青壮年，若治疗不及时易引发风湿热、肾小球肾炎等并发症。中医将其归为“乳蛾”“喉蛾”范畴，历代医家在该病治疗中积累了丰富经验。在临床中，连翘是治疗急性化脓性扁桃体炎的常用中药，具有疏散风热、清热解毒、消肿散结等功效。相应地，能够治疗此病且包含该中药的方剂有银翘散、桑菊饮、普济消毒饮、清咽利膈汤、凉膈散等。本文将通过阐述临床运用及现代药理研究总结连翘及其相关方剂治疗该病的优势与不足，为临床优化治疗方案及后续研究提供参考。","PeriodicalId":19889,"journal":{"name":"药学与临床研究","volume":"1 2","pages":"40-46"},"PeriodicalIF":0.0,"publicationDate":"2025-12-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.pangupress.com/journal/ebcm/1/2/11/pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147885218","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
一例鼻咽癌患者PICC导管异位引发上肢静脉血栓的原因分析与护理探讨 一例鼻咽癌患者PICC导管异位引发上肢静脉血栓的原因分析与护理探讨
药学与临床研究 Pub Date : 2025-12-27 DOI: 10.65140/ebcm202502.9
妍妍 胡, 蓉蓉 凌
{"title":"一例鼻咽癌患者PICC导管异位引发上肢静脉血栓的原因分析与护理探讨","authors":"妍妍 胡, 蓉蓉 凌","doi":"10.65140/ebcm202502.9","DOIUrl":"https://doi.org/10.65140/ebcm202502.9","url":null,"abstract":"目的 对1 例上肢静脉血栓合并经外周中心静脉置管（PICC）导管继发性异位患者的护理干预方案进行探究。方法 组织多学科联合会诊，通过对患者全身和局部症状的评估，结合血管超声、X线影像学检查和血常规、凝血功能实验室结果，运用批判性思维，对患者留置PICC期间导管继发性异位及上肢静脉血栓形成的诱发因素进行分析。具体包括：放射治疗导致患者免疫力下降，引起放射性肺炎，伴有咳嗽症状，同时胸腔内压力增加而引起的食欲下降、便秘等；化疗引起恶心、呕吐，使血黏度增高，化疗药物强烈刺激血管壁，引起静脉壁损伤；患者年龄偏大，体形偏胖，有头颈部肿瘤和糖尿病史，血液呈高凝状态，长期处于置管状态；置管侧身有上举过度的动作；导管先发生异位，末端未到达上腔静脉，管端上下前后移位，使血管内膜进一步受到刺激，诱发静脉血栓，随肢体活动或腔内压力的变化而发生。针对上述原因采取针对性处理措施，包括重力输液、患肢制动、全身抗凝治疗、局部外敷青敷膏消肿止痛，并实施全程精细化护理。结果 患者置管侧肢肿胀完全消退，疼痛症状减轻，X线检查显示导管复位到理想位置，血管超声提示右侧上肢静脉血液流通顺畅，全部治疗顺利完成，未出现其他相关并发症，带管安全出院。结论 PICC留置期间，在构建多学科协作和医护患者共同决策的护理模式的同时，提高患者自我管理意识和能力，开展个性化健康指导，实施精准化上肢功能锻炼，加强预防措施，及时评估风险，及早发现并发症，对于PICC的安全长期留置具有重要意义。","PeriodicalId":19889,"journal":{"name":"药学与临床研究","volume":"1 2","pages":"24-29"},"PeriodicalIF":0.0,"publicationDate":"2025-12-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.pangupress.com/journal/ebcm/1/2/9/pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147889669","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
氨甲环酸醇质体的制备及体外评价 氨甲环酸醇质体的制备及体外评价
药学与临床研究 Pub Date : 2024-02-15 DOI: 10.13664/j.cnki.pcr.2024.01.019
余胜男 | 姜伟化 | 杜子蝶 | 李念光 | 刘飞
{"title":"氨甲环酸醇质体的制备及体外评价","authors":"余胜男 | 姜伟化 | 杜子蝶 | 李念光 | 刘飞","doi":"10.13664/j.cnki.pcr.2024.01.019","DOIUrl":"https://doi.org/10.13664/j.cnki.pcr.2024.01.019","url":null,"abstract":"","PeriodicalId":19889,"journal":{"name":"药学与临床研究","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142032852","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
贝达喹啉治疗药物浓度监测方法的建立与应用 贝达喹啉治疗药物浓度监测方法的建立与应用
药学与临床研究 Pub Date : 2024-02-15 DOI: 10.13664/j.cnki.pcr.2024.01.005
王仲建 | 陈夏霖 | 张侠 | 张向荣 | 曹辉 | 王允吉
{"title":"贝达喹啉治疗药物浓度监测方法的建立与应用","authors":"王仲建 | 陈夏霖 | 张侠 | 张向荣 | 曹辉 | 王允吉","doi":"10.13664/j.cnki.pcr.2024.01.005","DOIUrl":"https://doi.org/10.13664/j.cnki.pcr.2024.01.005","url":null,"abstract":"","PeriodicalId":19889,"journal":{"name":"药学与临床研究","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142032853","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
大叶茜草素对人肝癌细胞生物学行为的影响及作用机制 大叶茜草素对人肝癌细胞生物学行为的影响及作用机制
药学与临床研究 Pub Date : 2023-08-10 DOI: 10.13683/j.wph.2023.08.004
陈博婷 | 郭小艳
{"title":"大叶茜草素对人肝癌细胞生物学行为的影响及作用机制","authors":"陈博婷 | 郭小艳","doi":"10.13683/j.wph.2023.08.004","DOIUrl":"https://doi.org/10.13683/j.wph.2023.08.004","url":null,"abstract":"","PeriodicalId":19889,"journal":{"name":"药学与临床研究","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-08-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142027516","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
汉黄芩素调节炎症通路对膝骨关节炎大鼠炎性损伤的影响 汉黄芩素调节炎症通路对膝骨关节炎大鼠炎性损伤的影响
药学与临床研究 Pub Date : 2023-06-10 DOI: 10.13683/j.wph.2023.06.007
李会东 | 杨学钰 | 郭文帆 | 郑雪君 | 卢吉高 | 杨勇
{"title":"汉黄芩素调节炎症通路对膝骨关节炎大鼠炎性损伤的影响","authors":"李会东 | 杨学钰 | 郭文帆 | 郑雪君 | 卢吉高 | 杨勇","doi":"10.13683/j.wph.2023.06.007","DOIUrl":"https://doi.org/10.13683/j.wph.2023.06.007","url":null,"abstract":"","PeriodicalId":19889,"journal":{"name":"药学与临床研究","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-06-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142027253","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
美托洛尔联合替罗非班对急性心肌梗死的疗效及对血清脂蛋白相关磷脂酶A2、生长分化因子-15、可溶性ST2蛋白的影响 美托洛尔联合替罗非班对急性心肌梗死的疗效及对血清脂蛋白相关磷脂酶A2、生长分化因子-15、可溶性ST2蛋白的影响
药学与临床研究 Pub Date : 2023-05-10 DOI: 10.13683/j.wph.2023.05.013
高雪松 | 刘慧慧 | 顾行军
{"title":"美托洛尔联合替罗非班对急性心肌梗死的疗效及对血清脂蛋白相关磷脂酶A2、生长分化因子-15、可溶性ST2蛋白的影响","authors":"高雪松 | 刘慧慧 | 顾行军","doi":"10.13683/j.wph.2023.05.013","DOIUrl":"https://doi.org/10.13683/j.wph.2023.05.013","url":null,"abstract":"","PeriodicalId":19889,"journal":{"name":"药学与临床研究","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-05-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142027107","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
髂筋膜间隙阻滞持续镇痛对老年髋部骨折患者术后疼痛及早期康复影响 髂筋膜间隙阻滞持续镇痛对老年髋部骨折患者术后疼痛及早期康复影响
Pharmaceutical and Clinical Research Pub Date : 2023-05-10 DOI: 10.13683/j.wph.2023.05.014
许旭霞 | 刘浩宇 | 康翠芸
{"title":"髂筋膜间隙阻滞持续镇痛对老年髋部骨折患者术后疼痛及早期康复影响","authors":"许旭霞 | 刘浩宇 | 康翠芸","doi":"10.13683/j.wph.2023.05.014","DOIUrl":"https://doi.org/10.13683/j.wph.2023.05.014","url":null,"abstract":"","PeriodicalId":19889,"journal":{"name":"Pharmaceutical and Clinical Research","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-05-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142027109","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
通过ERK/MAPK通路观察水飞蓟素对梗阻性黄疸大鼠肝细胞凋亡的影响 通过ERK/MAPK通路观察水飞蓟素对梗阻性黄疸大鼠肝细胞凋亡的影响
药学与临床研究 Pub Date : 2023-02-10 DOI: 10.13683/j.wph.2023.02.007
和燕 | 王晓萍 | 吴胜利 | 张淑玲
{"title":"通过ERK/MAPK通路观察水飞蓟素对梗阻性黄疸大鼠肝细胞凋亡的影响","authors":"和燕 | 王晓萍 | 吴胜利 | 张淑玲","doi":"10.13683/j.wph.2023.02.007","DOIUrl":"https://doi.org/10.13683/j.wph.2023.02.007","url":null,"abstract":"","PeriodicalId":19889,"journal":{"name":"药学与临床研究","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-02-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142026276","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
川陈皮素通过调控微RNA-374a-3p表达抑制氧化低密度脂蛋白诱导的人脑微血管内皮细胞损伤研究 川陈皮素通过调控微RNA-374a-3p表达抑制氧化低密度脂蛋白诱导的人脑微血管内皮细胞损伤研究
Pharmaceutical and Clinical Research Pub Date : 2022-12-10 DOI: 10.13683/j.wph.2022.12.005
刘拥军 | 李鹏 | 齐兵歌
{"title":"川陈皮素通过调控微RNA-374a-3p表达抑制氧化低密度脂蛋白诱导的人脑微血管内皮细胞损伤研究","authors":"刘拥军 | 李鹏 | 齐兵歌","doi":"10.13683/j.wph.2022.12.005","DOIUrl":"https://doi.org/10.13683/j.wph.2022.12.005","url":null,"abstract":"","PeriodicalId":19889,"journal":{"name":"Pharmaceutical and Clinical Research","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-12-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142070174","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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