Pakistan Journal of Neurological Sciences最新文献_第7页

Intravenous thrombolytic therapies in the management of unknown onset and wakeup strokes: A scoping review 静脉溶栓治疗在不明起病和醒后卒中中的应用:范围综述

Pakistan Journal of Neurological Sciences Pub Date : 2022-12-04 DOI: 10.56310/pjns.v17i02.184

Saima Nazish

{"title":"Intravenous thrombolytic therapies in the management of unknown onset and wakeup strokes: A scoping review","authors":"Saima Nazish","doi":"10.56310/pjns.v17i02.184","DOIUrl":"https://doi.org/10.56310/pjns.v17i02.184","url":null,"abstract":"Background : The efficacy and safety of thrombolytic therapies for the management of unknown time onset stroke (UTOS) and wake-up stroke (WUS) are in a debate. \u0000Objective: The objective of this scoping review is to map the existing research literature to answer the research question: What is the efficacy and safety of intravenous thrombolysis in the management of unknown time onset stroke? \u0000Data Sources: The literature search was conducted using the search terms {(Intravenous thrombolysis)} AND {(Unknown time onset stroke)} in pub med and Intravenous thrombolysis *, Unknown time onset stroke *in Cochrane. The review was limited to articles written in the English language. Databases searched included MEDLINE, PubMed and Cochrane electronic databases complemented with a manual search. \u0000Study Selection and Data Extraction: 45 articles of potential relevance were selected. Out of them 14 were containing relevant information direct to the question. The analysis was conducted by charting descriptive numerical data and by content analysis of the narrative representations \u0000 Results: From 14 relevant papers, 2 Retrospective observational, 2 case control, 1 pilot study, and 5 recent randomized control trials were included for critical appraisal and review writing. \u0000Conclusions: The penumbral mismatch in UTOS is a cogent method to recognize the patients for thrombolytic therapy without significant risk, but the appropriate imaging criteria to maximize the efficacy and minimize bleeding complications of thrombolytic treatment still has to be fully defined. Results from ongoing trials may be promising with the use of advanced imaging modalities in selected patients.","PeriodicalId":19818,"journal":{"name":"Pakistan Journal of Neurological Sciences","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-12-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80684031","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Churg Strauss syndrome with neuropathy: a case report 丘格·施特劳斯综合征伴神经病变1例

Pakistan Journal of Neurological Sciences Pub Date : 2022-12-04 DOI: 10.56310/pjns.v17i02.182

Zaid Waqar

引用次数: 0

Molecular analyses of Phenylketonuria in the intellectually disabled children from Faisalabad, Punjab, Pakistan 巴基斯坦旁遮普费萨拉巴德智障儿童苯丙酮尿的分子分析

Pakistan Journal of Neurological Sciences Pub Date : 2022-12-04 DOI: 10.56310/pjns.v17i02.168

Habiba Hussain, M. Wasim, Haq Nawaz Khan, Hina Ayesha, Fazli Rabbi Awan

引用次数: 1

Post COVID-19 vaccine (SINOVAC) cerebral venous sinus thrombosis 新冠肺炎疫苗后脑静脉窦血栓形成

Pakistan Journal of Neurological Sciences Pub Date : 2022-12-03 DOI: 10.56310/pjns.v17i02.185

Soban Khan, Mariam Khalil, Zaid Waqar

引用次数: 1

Prevalence of depression in caregivers of stroke patients in Karachi, Pakistan 巴基斯坦卡拉奇卒中患者护理人员抑郁患病率

Pakistan Journal of Neurological Sciences Pub Date : 2022-12-02 DOI: 10.56310/pjns.v17i02.192

Marium Mansoor, S. Pirani, Rabeeka Aftab, Tania Nadeem

{"title":"Prevalence of depression in caregivers of stroke patients in Karachi, Pakistan","authors":"Marium Mansoor, S. Pirani, Rabeeka Aftab, Tania Nadeem","doi":"10.56310/pjns.v17i02.192","DOIUrl":"https://doi.org/10.56310/pjns.v17i02.192","url":null,"abstract":"OBJECTIVES \u0000To determine the frequency of depression in caregivers of stroke patients at a tertiary care teaching hospital in Karachi Pakistan. \u0000 METHODS \u0000A cross-sectional study was conducted among caregivers of stroke, who were recruited from the Aga Khan University Hospital Karachi Pakistan, between January 2018 to October 2018. Data was collected through the Urdu Hamilton rating scale for depression (HAM-D-U) and it was analyzed using descriptive and inferential statistics. \u0000 RESULTS \u0000A total of 136 caregivers participated in the study. Among them, 44.1 % were male and 55.9% were female. The mean age of caregivers was 45.38 ± 10.33 years. Using the HAM-D-U scale, depression was present in 64 (47.1%) caregivers. Out of them (n=64), 46 (33.8%) caregivers had mild depression whereas 18 (13.2%) had moderate depression. Depression was found to have a significant relationship with the age of the patient (p=0.002), education level of caregiver (p= 0.012), employment status of caregiver (p=0.012), being a sole caregiver (p=0.039), and monthly family income (p=0.016). \u0000 CONCLUSIONS \u0000Caring for patients with neurological disorders is highly challenging and demanding. The need for this role may arise unexpectedly in one’s life; leaving little space for adjustment and coping. Depression itself can be very paralyzing for the sufferer especially if moderate to severe in intensity. Depression in stroke caregivers can be missed as patients are the center of a clinical visit. Hence, strategies should be designed and reinforced to screen patients and caregivers for depression along with a pathway for an easy and timely referral.","PeriodicalId":19818,"journal":{"name":"Pakistan Journal of Neurological Sciences","volume":"101 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-12-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79806148","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Practical measures for disabled’s empowerment- Time for economic growth! 残疾人赋权的实际措施——经济增长的时间到了!

Pakistan Journal of Neurological Sciences Pub Date : 2022-12-02 DOI: 10.56310/pjns.v17i02.195

M. Hafeez

引用次数: 0

A case of ulcerative colitis presenting with cerebral venous thrombosis 溃疡性结肠炎并发脑静脉血栓1例

Pakistan Journal of Neurological Sciences Pub Date : 2022-10-18 DOI: 10.56310/pjns.v17i01.177

Zaid Waqar

引用次数: 0

World Brain Day- brain health for all 世界大脑日——人人享有大脑健康

Pakistan Journal of Neurological Sciences Pub Date : 2022-10-18 DOI: 10.56310/pjns.v17i01.190

S. Younis

引用次数: 0

Stroke: Are women worse off? 中风:女性的情况更糟吗?

Pakistan Journal of Neurological Sciences Pub Date : 2022-10-18 DOI: 10.56310/pjns.v17i01.159

Maria Khan

引用次数: 0

Misperception about epilepsy among common public in Balochistan 俾路支省公众对癫痫的误解

Pakistan Journal of Neurological Sciences Pub Date : 2022-10-18 DOI: 10.56310/pjns.v17i01.165

Muhammad Essa, Gulandam, Aman ullah Kakar, Saleem Barech, Ihsan ul haq zarkon, Suhail Mari, Muhammad Dawood, Tahir Shah

{"title":"Misperception about epilepsy among common public in Balochistan","authors":"Muhammad Essa, Gulandam, Aman ullah Kakar, Saleem Barech, Ihsan ul haq zarkon, Suhail Mari, Muhammad Dawood, Tahir Shah","doi":"10.56310/pjns.v17i01.165","DOIUrl":"https://doi.org/10.56310/pjns.v17i01.165","url":null,"abstract":"Abstract \u0000Background of the Study: \u0000Epilepsy is a curable chronic neurological illness that is frequently associated to supernatural activity. Due to a lack of knowledge and awareness among the Common public. The objectives of this study were to determine common myths and misperception about epilepsy by analysing a comprehensive panel of variables in our local population. Methods: We conducted a face-to-face questionnaire interview survey in three different shopping malls 1000 people were randomly enrolled in this cross-sectional study at Quetta, Baluchistan, during the period of twenty-one august 2021 to 30 august 2021. \u0000Results: A total of 1000 people were interviewed among them 220(22%) were male and 780(78%) were female. People of all age group were included in the study. Out of thousand people 419 (41.9%) says epilepsy is brain disease, 488 (48.8%) responds its ghost attack, 23(2.3%) believes its psychosis. 980(98%) respondents had heard about epilepsy. The aspects of knowledge tested were on causes, types, and management of epilepsy. Forty-nine (4.9%) people believes that cause of epilepsy is head trauma, 488 (48.8%) said its Ghost attack, 67 (6.7%) said it’s because of evil eye, and 293 (29.3%) peoples believes that epilepsy is caused by Black magic. 928 (92.8%) who believed on domestic stunts such as sniffing shoes is effective in epilepsy. This result was much surprising because in this era of modern medicine and technology, still superstitious believes prevail among large population \u0000Conclusions: This study revealed a lack of awareness about epilepsy in Baluchistan, as well as the prevalence of both negative and favourable attitudes about Epilepsy. The study also emphasized to increase public awareness and epilepsy education initiatives to change public opinions and promote the use of standard epileptic treatment \u0000Keywords: Epilepsy, Attitudes, Knowledge","PeriodicalId":19818,"journal":{"name":"Pakistan Journal of Neurological Sciences","volume":"97 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-10-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86367400","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0