Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy最新文献_第10页

Cost‐Effectiveness Analysis of Second‐Line Chemotherapy Agents for Advanced Gastric Cancer 晚期胃癌二线化疗药物的成本-效果分析

Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy Pub Date : 2017-01-01 DOI: 10.1002/phar.1870

S. Lam, Maya Wai, J. Lau, M. Mcnamara, M. Earl, B. Udeh

引用次数: 13

Managing the Rising Costs and High Drug Expenditures in Critical Care Pharmacy Practice 管理成本上升和高药费在重症药学实践

Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy Pub Date : 2017-01-01 DOI: 10.1002/phar.1862

Alexander H. Flannery, Komal Pandya, Melanie E. Laine, Philip J. Almeter, J. Flynn

{"title":"Managing the Rising Costs and High Drug Expenditures in Critical Care Pharmacy Practice","authors":"Alexander H. Flannery, Komal Pandya, Melanie E. Laine, Philip J. Almeter, J. Flynn","doi":"10.1002/phar.1862","DOIUrl":"https://doi.org/10.1002/phar.1862","url":null,"abstract":"Pharmaceutical costs for patients in the intensive care unit (ICU) constitute a large portion of hospital drug budgets. Unfortunately, prices for medications commonly used in the ICU are on the rise for a variety of reasons. In particular, the U.S. Food and Drug Administration's Unapproved Drugs Initiative, generic manufacturers cornering the marketplace, drug shortages, and regulatory device changes are major drivers of pharmaceutical price escalation affecting costs in the ICU. Furthermore, traditional high acquisition cost items still pose challenges to controlling costs. To offer strategies to mitigate the rising costs of pharmaceuticals in the ICU setting, we searched the PubMed/Medline and International Pharmaceutical Abstracts databases and other related sources to identify published cost‐saving protocols concerning specific medications that are affected by rising prices or have traditional high acquisition costs. In the absence of specific protocols, we offer possible cost‐saving initiatives based on published literature regarding specific agents or based on our own diverse set of experiences. Finally, we review suggested clinical and operational activities at an institutional level to address these rising drug costs in the ICU setting.","PeriodicalId":19812,"journal":{"name":"Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy","volume":"159 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2017-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87878027","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 19

Spending on Hepatitis C Antivirals in the United States, 2009–2015 2009-2015年美国丙型肝炎抗病毒药物支出

Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy Pub Date : 2017-01-01 DOI: 10.1002/phar.1865

K. Suda, Drew J. Halbur, R. Hunkler, Linda M. Matusiak, G. Schumock

引用次数: 8

Clinical Outcomes of Extended Versus Intermittent Infusion of Piperacillin/Tazobactam in Critically Ill Patients: A Prospective Clinical Trial 延长输注哌拉西林/他唑巴坦与间歇输注哌拉西林/他唑巴坦对危重患者的临床效果:一项前瞻性临床试验

Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy Pub Date : 2017-01-01 DOI: 10.1002/phar.1875

Sheung-Yin Fan, H. Shum, W. Cheng, Yat-Hei Chan, Sik-Yin McShirley Leung, W. Yan

引用次数: 23

Cost‐Effectiveness of Histamine2 Receptor Antagonists Versus Proton Pump Inhibitors for Stress Ulcer Prophylaxis in Critically Ill Patients 组胺2受体拮抗剂与质子泵抑制剂在危重患者应激性溃疡预防中的成本-效果

Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy Pub Date : 2017-01-01 DOI: 10.1002/phar.1859

Drayton A. Hammond, Niranjan Kathe, Anuj Shah, B. Martin

引用次数: 22

White Paper on Natural Products 天然产品白皮书

Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy Pub Date : 2017-01-01 DOI: 10.1002/phar.1874

M. Gabay, Judith A. Smith, M. Chavez, M. Goldwire, Scot Walker, Scott A Coon, Rena A. Gosser, A. Hume, M. Musselman, Jennifer A. Phillips, Andrew M. Abe

{"title":"White Paper on Natural Products","authors":"M. Gabay, Judith A. Smith, M. Chavez, M. Goldwire, Scot Walker, Scott A Coon, Rena A. Gosser, A. Hume, M. Musselman, Jennifer A. Phillips, Andrew M. Abe","doi":"10.1002/phar.1874","DOIUrl":"https://doi.org/10.1002/phar.1874","url":null,"abstract":"The American College of Clinical Pharmacy (ACCP) published an initial white paper on herbal products in 2000. Since then, the global market for natural products has continued to expand, with tens of millions of consumers using such products on an annual basis in the United States alone. However, despite this expansion, natural products remain largely unregulated compared with prescription medications, have moderate‐ to low‐level clinical evidence for efficacy, and continue to have safety concerns, including adulteration and misbranding. As comprehensive medication management experts, clinical pharmacists are uniquely qualified to navigate these concerns and advise patients appropriately. To develop and recommend a suitable care plan involving natural products, clinical pharmacists must establish a strong pharmacist‐patient relationship, assess the appropriateness of therapy, educate the patient regarding key issues, and continuously monitor and follow up on the effectiveness of the care plan. This process should not only occur in an individual community or hospital setting, but also whenever a patient transitions from one care setting to another in cooperation with other clinicians.","PeriodicalId":19812,"journal":{"name":"Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy","volume":"24 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2017-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73729098","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 15

Operational and Clinical Strategies to Address Drug Cost Containment in the Acute Care Setting 业务和临床战略，以解决药物成本控制在急症护理设置

Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy Pub Date : 2017-01-01 DOI: 10.1002/phar.1858

K. McConnell, O. Guzman, Nisha Pherwani, D. Spencer, Jennifer D Van Cura, K. Shea

引用次数: 10

Clinical Experience with Daptomycin in Pediatrics 达托霉素在儿科的临床应用体会

Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy Pub Date : 2017-01-01 DOI: 10.1002/phar.1872

Katie C. Namtu, Julianna C. Crain, Allison F. Messina, J. Dumois, D. Berman

引用次数: 8

Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy Pub Date : 2017-01-01 DOI: 10.1002/phar.1876

J. Warnock, L. Cohen, H. Blumenthal, J. Hammond

引用次数: 14

Potential Association between Drug Shortages and High‐Cost Medications 药物短缺与高成本药物之间的潜在联系

Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy Pub Date : 2017-01-01 DOI: 10.1002/phar.1861

E. Fox, L. Tyler

引用次数: 23