The Ewha Medical Journal最新文献_第9页

Acute Vulvar Ulcer (Lipschutz Ulcer) in a Sexually Inactive 11-Yearold Girl 性行为不活跃的11岁女孩急性外阴溃疡(Lipschutz溃疡)

The Ewha Medical Journal Pub Date : 2021-01-31 DOI: 10.12771/EMJ.2021.44.1.26

K. Cho, S. Kim, Ji Hyen Lee

引用次数: 1

Listeriosis in a Pregnant Woman and a Neonate 孕妇和新生儿的李斯特菌病

The Ewha Medical Journal Pub Date : 2020-10-31 DOI: 10.12771/emj.2020.43.4.60

H. Yun, Juhui Kim, S. Cho, E. Park, Y. J. Kim, Sunwha Park

引用次数: 1

Acquired Hypopituitarism in Diamond-Blackfan Anemia 钻石-黑扇贫血的后天性垂体功能减退

The Ewha Medical Journal Pub Date : 2020-10-31 DOI: 10.12771/emj.2020.43.4.65

Ji Yun Yun, Jung Eun Choi, H. Kim, K. Ryu

引用次数: 0

Incidental Findings on Brain Magnetic Resonance Imaging in Children with Central Precocious Puberty 中枢性性性早熟儿童的脑磁共振成像附带发现

The Ewha Medical Journal Pub Date : 2020-10-31 DOI: 10.12771/emj.2020.43.4.53

J. Kim, Ji Hyen Lee, Hyun-Hae Cho, H. Kim

{"title":"Incidental Findings on Brain Magnetic Resonance Imaging in Children with Central Precocious Puberty","authors":"J. Kim, Ji Hyen Lee, Hyun-Hae Cho, H. Kim","doi":"10.12771/emj.2020.43.4.53","DOIUrl":"https://doi.org/10.12771/emj.2020.43.4.53","url":null,"abstract":"Objectives: To investigate brain magnetic resonance imaging (MRI) findings in patients with central precocious puberty (CPP) by age at onset and sex. Methods: We included 130 CPP patients with brain MRI findings of the pituitary gland treated at Ewha Womans University Mokdong Hospital between February 2007 and October 2013 and divided them by age and sex: boys, girls aged ≤6 years, and girls aged >6 years. The control group comprised 224 patients who underwent brain MRIs, and we compared their incidental brain findings with those of the CPP group. Results: In the CPP subgroups who underwent pituitary MRIs, the frequency of incidental brain lesions was 31.6% in boys, 47.1% in girls ≤6 years and 29.8% in girls >6 years. The incidence of pituitary abnormalities was 42.1% in boys, 64.7% in girls ≤6 years and 47.9% in girls >6 years. Among pituitary abnormalities, pituitary hypoplasia had a significantly higher incidence rate in girls ≤6 years (41.2%) than in boys (15.8%) or girls >6 years (13.8%, P=0.027). Hypothalamic hamartomas were detected in one girl aged ≤6 years and in one boy, but not in girls aged 6 years (P=0.075). The incidence of pineal cysts was higher in the CPP groups and significantly higher in girls ≤6 years (47.1%) than in the control group (11.2%, P=0.001). Conclusion: There was a higher incidence of brain abnormalities on pituitary MRIs and a higher incidence of pineal cysts, possibly associated with CPP pathogenesis, in younger CPP patients than in other patients. (Ewha Med J 2020;43(4):53-59) Received June 25, 2020 Revised July 30, 2020 Accepted August 24, 2020","PeriodicalId":197820,"journal":{"name":"The Ewha Medical Journal","volume":"80 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-10-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131660111","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Performance of Xpert Carba-R Assay for Identification of Carbapenemase Gene in the Clinical Microbiology Laboratory Xpert碳- r法鉴定碳青霉烯酶基因在临床微生物实验室中的应用

The Ewha Medical Journal Pub Date : 2020-07-31 DOI: 10.12771/emj.2020.43.3.39

Hae-Sun Chung, N. Yang, Y. Kim, Miae Lee, Sholhui Park

{"title":"Performance of Xpert Carba-R Assay for Identification of Carbapenemase Gene in the Clinical Microbiology Laboratory","authors":"Hae-Sun Chung, N. Yang, Y. Kim, Miae Lee, Sholhui Park","doi":"10.12771/emj.2020.43.3.39","DOIUrl":"https://doi.org/10.12771/emj.2020.43.3.39","url":null,"abstract":"Objectives: The Xpert Carba-R Assay is a diagnostic test designed for the rapid detection and differentiation of the bla KPC , bla NDM , bla VIM , bla OXA-48 , and bla IMP-1 genes. We verified the performance of Xpert Carba-R Assay for identification of carbapenemase gene in the clinical microbiology laboratory. Methods: The analytical limit of detection was determined with two suspensions of carbapenemase-producing Enterobacteriaceae (CPE) isolates (KPC and NDM). A total of 52 specimens were evaluated: 21 bacterial isolates from clinical specimens, 21 rectal swabs, and 10 contrived stool specimens. Results: In bacterial isolates, concordant results between the Xpert Carba-R Assay and PCR were found in 20 of 21; 8 KPC, 8 NDM, 1 IMP, and 2 multiple carbapenamase genes (KPC/NDM, NDM/OXA) were detected both by Xpert Carba-R Assay and PCR. In one GES-positive isolate, Xpert Carba-R Assay showed a negative result as expected. One VIM-positive isolate tested negative by Xpert Carba-R Assay. Complete concordance was seen in rectal swab specimens: 4 specimens with KPC and 17 specimens with negative results both by Xpert Carba-R Assay and surveillance culture. Among the 10 contrived stool specimens, Xpert Carba-R Assay detected carbapenemase genes in 9 specimens as expected according to the CPE strains spiked into the contrived stool; 2 KPC, 4 NDM, 1 IMP, and 2 multiple carabapenamase genes (NDM/KPC, NDM/OXA). One VIM-positive specimen tested negative by Xpert Carba-R Assay. Conclusion: In conclusion, the Xpert Carba-R Assay can be used to identify carbapenemase gene in bacterial isolates cultured from clinical specimens and detect CPE carrier using rectal swab in clinical laboratories. (Ewha Med J 2020;43(3):39-42)","PeriodicalId":197820,"journal":{"name":"The Ewha Medical Journal","volume":"192 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-07-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129318668","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Anesthetic Management during Electroconvulsive Therapy 电休克治疗期间的麻醉管理

The Ewha Medical Journal Pub Date : 2020-07-31 DOI: 10.12771/emj.2020.43.3.49

Youbin Jo, Heeseung Lee, Soo In Kim, Dong Yeon Kim, H. Baik, R. K. Chung

引用次数: 0

Application of Six Sigma Metrics to Improve Quality Control for Point-of-care Glucose Testing 六西格玛指标在改善即时血糖检测质量控制中的应用

The Ewha Medical Journal Pub Date : 2020-07-31 DOI: 10.12771/emj.2020.43.3.43

Sholhui Park, Wookeun Lee, Tae-Dong Jeong, Hae-Sun Chung, K. Hong

{"title":"Application of Six Sigma Metrics to Improve Quality Control for Point-of-care Glucose Testing","authors":"Sholhui Park, Wookeun Lee, Tae-Dong Jeong, Hae-Sun Chung, K. Hong","doi":"10.12771/emj.2020.43.3.43","DOIUrl":"https://doi.org/10.12771/emj.2020.43.3.43","url":null,"abstract":"Objectives: Six sigma is a quality management system for the assessment of precision and accuracy. We aim to apply the six sigma rule to quality control (QC) of point-of-care (POC) glucose meters in a tertiary hospital. Methods: Thirty POC glucose meters installed at Ewha Womans University Mokdong Hospital were monitored between January 2013 and March 2014. The QC data from the POC glucose meters at low and high levels were collected. The monthly mean, standard deviation, bias, coefficient of variation, and mean sigma metrics were calculated. The correlation between accuracy and precision was assessed based on the percentage bias and coefficient of variation. Comprehensive instructions on the QC and maintenance of the devices were provided in the departments with poor sigma scores. A follow-up assessment was performed after the intervention. Results: The mean sigma values for the low and high controls were 3.29 and 3.71, respectively. At the low and high controls, 36.6% and 10% of the glucose meters showed a sigma value <3. The causes of low sigma values included the use of expired control materials, prolonged air exposure of the sample strip, lack of user training, and errors in device maintenance. On follow-up monitoring for 3 months following QC intervention, 23.3% (low control) and 6.6% (high control) of the glucose meters scored a sigma value <3, indicating improved QC. Conclusion: Sigma metrics-based QC can successfully improve accuracy and precision of POC glucose meters in an objective and quantitative manner and can be used for follow up after QC intervention. (Ewha","PeriodicalId":197820,"journal":{"name":"The Ewha Medical Journal","volume":"30 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-07-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122123669","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Severe Acute Kidney Injury with Familial Renal Hypouricemia Confirmed by Genotyping of SLC22A12 SLC22A12基因分型证实严重急性肾损伤伴家族性肾性低尿酸血症

The Ewha Medical Journal Pub Date : 2020-04-30 DOI: 10.12771/emj.2020.43.2.35

C. Cho, H. Cheong, Jung Won Lee

引用次数: 0

Future Role of Neurosurgeons: Toward Convergence Neurosurgeon Beyond Hybrid Neurosurgeon 神经外科医生的未来角色:走向融合神经外科医生超越混合神经外科医生

The Ewha Medical Journal Pub Date : 2020-04-30 DOI: 10.12771/emj.2020.43.2.25

N. Yang

{"title":"Future Role of Neurosurgeons: Toward Convergence Neurosurgeon Beyond Hybrid Neurosurgeon","authors":"N. Yang","doi":"10.12771/emj.2020.43.2.25","DOIUrl":"https://doi.org/10.12771/emj.2020.43.2.25","url":null,"abstract":"With advances in medicine and technology, treatment modalities for diseases have evolved. Consequently, physicians’ roles have also changed. Because of advances in endovascular treatment, neurosurgeons specializing in cerebrovascular surgery are increasingly using endovascular techniques. Accordingly, the number of so-called “hybrid neurosurgeons” who perform both traditional craniotomy cerebrovascular surgeries and endovascular treatments is on the rise. This phenomenon is also occurring in department of neurology, traditionally a non-surgical specialty, and the number of neurologists using endovascular treatments is also increasing. Nowadays endovascular treatments become more common across medical specialties such as neurointerveional radiology, neurosurgery, and neurology. In this time, what should be the role of neurosurgeons? Standardized hybrid surgeons should contribute to society by treating hemorrhagic stroke and ischemic stroke, maintaining a proper number of hybrid-neurosurgeons to ensure demand for such treatments is met. Further, more neurosurgeons should be trained to perform sophisticated traditional surgeries, as these surgeries cannot be performed by anyone else. Finally, neurosurgery patients often require a combination of surgical and medical treatment. In these situations, primary and secondary prevention are also crucial. And, many neurosurgery patients also have psychoneurotic symptoms. Within neurosurgery backgrounds, we, neurosurgeons, need to be intensivists for critical care medicine, hospitalization experts, epidemiologists, neuropsychiatry experts, and basic researchers. Because we have to be in charge of neurosurgical patients with various problems in our healthcare environment. Therefore, advancing beyond hybrid neurosurgeons and beginning an era of convergence neurosurgeons should be our role in the future. (Ewha Med J 2020;43(2):25-28) Received December 24, 2019 Revised January 30, 2020 Accepted February 10, 2020","PeriodicalId":197820,"journal":{"name":"The Ewha Medical Journal","volume":"33 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-04-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125268610","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Safety and Effectiveness of Indwelling Percutaneous Drainage in Hospitalized Terminally Ill Cancer Patients with Recurrent Ascites 经皮留置引流治疗晚期肿瘤复发性腹水的安全性和有效性

The Ewha Medical Journal Pub Date : 2020-04-30 DOI: 10.12771/emj.2020.43.2.29

Kwonoh Park, Geongsil Lee, Jae-Joon Kim, Sang-Bo Oh, S. Oh, E. Park, J. Kim, J. Jang, U. Jeon

{"title":"Safety and Effectiveness of Indwelling Percutaneous Drainage in Hospitalized Terminally Ill Cancer Patients with Recurrent Ascites","authors":"Kwonoh Park, Geongsil Lee, Jae-Joon Kim, Sang-Bo Oh, S. Oh, E. Park, J. Kim, J. Jang, U. Jeon","doi":"10.12771/emj.2020.43.2.29","DOIUrl":"https://doi.org/10.12771/emj.2020.43.2.29","url":null,"abstract":"Objectives: Terminally ill cancer patients in hospice palliative care unit are reluctant to undergo repetitive invasive procedures due to coagulopathies and poor performance or condition, while catheter management such as regular irrigation during hospitalization is easy. The purpose of this study was to investigate the safety and efficacy of indwelling intraperitoneal (IP) catheter in hospitalized terminally ill cancer patients with recurrent ascites. Methods: A retrospective review was conducted in patients who underwent IP catheter at the hospice palliative care unit of Pusan National University Yangsan Hospital between August 2016 and June 2018. All catheters were inserted by interventional radi-ologists with radiological guidance. The primary end-points were functional IP catheter maintenance rate, which is catheter maintained with patency for drainage until the intended time. Results: A total of 25 terminally ill cancer patients underwent IP catheters placements during the study period. All catheters were successfully inserted without major complications, but one patient had trivial bleeding and one other patient had temporary pain. The median time from admission to catheter insertion was 5 days (range, 1 to 49 days). Twenty-one catheters were maintained with function until the intended time, three cases were maintained without function, and the last one was removed early due to obstruction and pain. Finally, the functional IP maintenance rate was 84% (21/25) and the median functional catheter life span was 15 days (95% confidence interval, 10.8 to 17.2). Conclusion: Our study showed relatively favorable results for IP catheter maintenance and safety in hospitalized terminally ill cancer patients with malignant ascites. (Ewha Med J 2020;43(2):29-34)","PeriodicalId":197820,"journal":{"name":"The Ewha Medical Journal","volume":"118 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-04-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116369067","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0