Nihon Jinzo Gakkai shi最新文献_第6页

[Clinical and pathological features of nephrosclerosis]. 【肾硬化的临床病理特点】。

Nihon Jinzo Gakkai shi Pub Date : 2016-01-01

Kengo Furuichi, Takashi Wada

引用次数: 0

Rapidly progressive glomerulonephritis: recent advances. 快速进行性肾小球肾炎:最新进展。

Nihon Jinzo Gakkai shi Pub Date : 2016-01-01

Joichi Usui, Shuzo Kaneko, Kunihiro Yamagata, Michio Nagata

引用次数: 0

Effector and upstream mechanism of immune-mediated glomerulonephritis. 免疫介导的肾小球肾炎的效应物及上游机制。

Nihon Jinzo Gakkai shi Pub Date : 2016-01-01

Shun Manabe, Michio Nagata

引用次数: 0

[Contrast-induced nephropathy]. (对比感应肾病)。

Nihon Jinzo Gakkai shi Pub Date : 2016-01-01

Yoshinori Taniguchi, Yoshio Terada

引用次数: 0

[A case of renal Fanconi syndrome due to Bence Jones' protein K-type multiple myeloma]. 【Bence Jones蛋白k型多发性骨髓瘤致肾Fanconi综合征1例】。

Nihon Jinzo Gakkai shi Pub Date : 2016-01-01

Miho Inomata, Koki Tokunaga, Mai Nakahara, Hiroyuki Deguchi, Takuma Kojyo, Masaharu Abe, Miki Oyamada, Man-Ei Oku, Akio Ido

{"title":"[A case of renal Fanconi syndrome due to Bence Jones' protein K-type multiple myeloma].","authors":"Miho Inomata, Koki Tokunaga, Mai Nakahara, Hiroyuki Deguchi, Takuma Kojyo, Masaharu Abe, Miki Oyamada, Man-Ei Oku, Akio Ido","doi":"","DOIUrl":"","url":null,"abstract":"A 60-year-old man, who had been treated for chronic kidney disease and chronic hepatitis B infection, was referred to our hospital following presentation with thoracic bone pain and exacerbation of proteinuria and hematu- ria. On admission, laboratory test results showed evidence of hypophosphatemia, glucosuria and elevated levels of both urinary NAG and 62MG.The patient was diagnosed with Fanconi syndrome based on findings indicating the presence of pan-aminoaciduria, elevated urinary excretion of uric acid and an increased phosphorus reabsorption rate. Furthermore, bone scintigraphy showed increased multiple symmetric uptake of radiotracer in both sides of the ribs, leading to the diagnosis\"of hypoposphatemia-related osteomalacia with renal Fanconi syndrome. Urinary immunoelectrophoresis indicated the presence of K Bence Jones' protein (BJP). A bone marrow biopsy examina- tion showed that the plasma-to-cell ratio was less than 10%. However, the patient had over lg/day of proteinuria and suppression of serum IgM (18mg/dL) and was, therefore, diagnosed with multiple myeloma based on SWOG criteria. Light microscopic examination showed evidence of glomerulosclerosis, intimal thickness of interlobular arteries and acidophilic granular deposits in the cytoplasm of the proximal epithelial tubular cells. Immunofluores- cence indicated positive anti-K staining in these regions. Electron microscopic examination of the proximal tubular epithelial cells revealed the presence of numerous diamond-shaped and oval crystals, thought to be the K light chain of BJP. In general, cast nephropathy, light chain deposition disease (LCDD) and AL amyloidosis are recog- nized renal injuries caused by myeloma. However, there have been few clinical reports of Fanconi syndrome with multiple myeloma, such as the case study we have described here. In addition, histological examination of a biopsy sample provided further evidence of K BJP in the proximal epithelial tubular cells.","PeriodicalId":19721,"journal":{"name":"Nihon Jinzo Gakkai shi","volume":"58 7","pages":"1088-1094"},"PeriodicalIF":0.0,"publicationDate":"2016-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36888031","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[Association of blood pressure control effects on renal impairment with urinary protein: a study on the validity of the Japanese Society of Hypertension Guidelines for Management of Hypertension 2014]. [尿蛋白与血压控制对肾功能损害的影响:日本高血压学会高血压管理指南2014有效性的研究]。

Nihon Jinzo Gakkai shi Pub Date : 2016-01-01

Yumiko Mizukaki, Toshiharu Maruyama, Hiroaki Hamada, Takashi Maruyama, Atsushi Satomura, Shinya Kawamoto, Yushi Sudo

{"title":"[Association of blood pressure control effects on renal impairment with urinary protein: a study on the validity of the Japanese Society of Hypertension Guidelines for Management of Hypertension 2014].","authors":"Yumiko Mizukaki, Toshiharu Maruyama, Hiroaki Hamada, Takashi Maruyama, Atsushi Satomura, Shinya Kawamoto, Yushi Sudo","doi":"","DOIUrl":"","url":null,"abstract":"Background and objective: Progression of chronic kidney disease (CKD) leads to the onset of cardiovascular dis- eases and an increase in the number of patients requiring dialysis initiation. In prder to promote the early detection and treatment of CKD, we assessed the effects of blood pressure control on renal impairment based on common test items and verified the usefulness of the target blood pressure for patients with CKD described in the Japanese Society of Hypertension Guidelines for the Management of Hypertension in 2014 (JSH 2014).Subjects and methods: Among patients who had been regularly visiting the outpatient clinic of Kasukabe Kisen Hospital for 24 months or more, 67 with a serum creatinine level of 1.2 mg/dL or higher were included in this study. Clinical blood pressure measurements obtained at the start of follow-up and at 6, 12, 18, and 24 months were averaged to serve as the 2-year mean blood pressure, and the progression rates of renal impairment were com- pared between patients achieving and those not achieving the target blood pressure of the JSH 2014.Results: Among the diabetic patients with CKD, significant differences in renal impairment progression rates were observed between those achieving and those not achieving the target blood pressure. Among the non-diabetic patients with CKD, those achieving the target blood pressure tended to show slower progression of renal impair- ment, but their progression rates were not significantly different from those of the patients not achieving the target blood pressure.Conclusion: Blood pressure control is essential for patients with CKD. In patients with diabetes mellitus, the pro- gression rates of renal impairment can be substantially reduced by maintaining blood pressure below the target blood pressure described in the JSH 2014.","PeriodicalId":19721,"journal":{"name":"Nihon Jinzo Gakkai shi","volume":"58 7","pages":"1083-1087"},"PeriodicalIF":0.0,"publicationDate":"2016-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36888030","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[Epidemiology and clinical significance of nephrosclerosis]. 肾硬化的流行病学及临床意义。

Nihon Jinzo Gakkai shi Pub Date : 2016-01-01

Hiroshi Sato, Hitoshi Sugiyama, Hiroshi Morinaga, Hitoshi Yokoyama

引用次数: 0

[Molecular targeted therapy in kidney transplantation]. [分子靶向治疗肾移植]。

Nihon Jinzo Gakkai shi Pub Date : 2016-01-01

Kazuhide Saito

引用次数: 0

Pathology of membranoproliferative glomerulonephritis (MPGN): past, present and future. 膜增生性肾小球肾炎(MPGN)的病理:过去、现在和未来。

Nihon Jinzo Gakkai shi Pub Date : 2016-01-01

Kazubo Honda