Pacific Medical Journal最新文献

Open educational resources for medical community 面向医学界的开放式教育资源

Pacific Medical Journal Pub Date : 2024-05-19 DOI: 10.34215/1609-1175-2024-1-92-99

L. L. Sadovskaya

{"title":"Open educational resources for medical community","authors":"L. L. Sadovskaya","doi":"10.34215/1609-1175-2024-1-92-99","DOIUrl":"https://doi.org/10.34215/1609-1175-2024-1-92-99","url":null,"abstract":"The study reveals the great importance of open educational resources (OER) in the field of medical education and scientific activity. Objective. To develop an “OER navigator for medical community”, containing metadata of information resources with open free access. These resources are intended for use in curricula at all stages of medical education, in scientific activities and self-education. At the present stage, the social significance of education in terms of the world concept of “sustainable development” is defined as the most important component and means of survival for civilization (UNESCO). In medicine, with its special mission to preserve the health of the population, the urgent task consists in the training of highly qualified personnel. Close connection of the future of mankind with the processes of digitalization determines the availability of information resources and the use of modern technologies as key aspects of the organization of educational processes. The analysis of the scientific literature and the study of the experience of OER application revealed that OER represent an important tool in the information support of the scientific and educational sphere. OER contribute to forming a personal educational environment, learning continuously and improving skills worldwide, in perpetuity and regardless of financial capabilities. The amount of data presented on the Internet is huge, therefore, the search for necessary information takes a significant amount of time. The developed Navigator (http://lib-os.ru/obrazovatelnye-resursy/navigator-oor-medicinskogo-soobshhestva/) provides meta-data of information resources with open free access, thereby allowing representatives of the medical community at all levels of education and research to quickly and effectively find reliable scientific data and peer-reviewed sources of information.","PeriodicalId":19705,"journal":{"name":"Pacific Medical Journal","volume":"120 27","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141124161","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Difficulties in the diagnosis of spinal tuberculosis (clinical observation) 脊柱结核的诊断困难（临床观察）

Pacific Medical Journal Pub Date : 2024-05-19 DOI: 10.34215/1609-1175-2024-1-75-78

G. A. Torohtij, S. A. Belov

引用次数: 0

Using flow-vacuum-washing isolation device for comprehensive treatment of maxillofacial purulent-inflammatory wounds 使用流动真空清洗隔离装置综合治疗颌面部化脓性炎症伤口

Pacific Medical Journal Pub Date : 2024-05-19 DOI: 10.34215/1609-1175-2024-1-88-91

M. K. Kubanychbekov, D. B. Shayakhmetov, D. A. Adambekov, A. R. Tsoi, I. S. Aldzhambayeva

引用次数: 0

Case of successful treatment of spinal infection in a patient with high comorbidity and septic manifestations 成功治疗一名高度合并症和脓毒症患者脊柱感染的病例

Pacific Medical Journal Pub Date : 2024-05-19 DOI: 10.34215/1609-1175-2024-1-82-87

A. Yarikov, A. Vishnevsky, A. S. Filyaeva, E. A. Pavlova, O. Perlmutter, A. Fraerman, V. N. Voloshin

引用次数: 0

Clinical case of median arcuate ligament syndrome in the practice of a pediatric surgeon 一名小儿外科医生的正中弓形韧带综合征临床病例

Pacific Medical Journal Pub Date : 2024-05-19 DOI: 10.34215/1609-1175-2024-1-79-81

N. A. Surkov, O. M. Dondup, F. S. Piloyan, D. M. Redkina, A. A. Zaripova

{"title":"Clinical case of median arcuate ligament syndrome in the practice of a pediatric surgeon","authors":"N. A. Surkov, O. M. Dondup, F. S. Piloyan, D. M. Redkina, A. A. Zaripova","doi":"10.34215/1609-1175-2024-1-79-81","DOIUrl":"https://doi.org/10.34215/1609-1175-2024-1-79-81","url":null,"abstract":"Recurrent abdominal pain in childhood and adolescence may be indicative of chronic mesenteric ischemia with median arcuate ligament syndrome as a result of compression of the celiac artery by the median arcuate ligament of the diaphragm and its internal crura, neurofibrous tissue of the celiac plexus. The presence of symptoms characteristic of various diseases of gastrointestinal tract organs, absence of pathognomonic signs and complex approach in diagnostics of abdominal cavity vascular system, insufficient awareness of specialists of children’s outpatient clinics determine the urgency of timely diagnostics and treatment of patients with this pathology. Median arcuate ligament syndrome, or Dunbar syndrome, is more often a congenital malformation. This syndrome can be considered as an acquired pathology in the case of compression of the celiac artery by enlarged lymph nodes and neurofibrous tissue of the celiac plexus. In addition to hemodynamically significant disorders of blood supply to the gastrointestinal tract, Dunbar syndrome in children and adolescents is also accompanied by psycho-emotional disorders due to the presence of unstable stools, recurrent abdominal pain, and often repeated ineffective requests for medical care. Clinical observation, methods of diagnosis and surgical treatment of median arcuate ligament syndrome in a 14-year-old patient are presented in the study.","PeriodicalId":19705,"journal":{"name":"Pacific Medical Journal","volume":"30 9","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141124003","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Fatal case of haemorrhagic fever with renal syndrome 肾综合征出血热死亡病例

Pacific Medical Journal Pub Date : 2024-05-18 DOI: 10.34215/1609-1175-2024-1-72-74

A. F. Popov, V. Ivanis, V. I. Verkhoturova, E. V. Safronova, T. A. Kabantsevа, S. I. Yehlakov, V. А. Pavlov

引用次数: 0

Comparative characterization of interleukin genotypes and risks of bronchial asthma phenotypes in children 白细胞介素基因型与儿童支气管哮喘表型风险的比较表征

Pacific Medical Journal Pub Date : 2024-05-18 DOI: 10.34215/1609-1175-2024-1-5-10

V. B. Shumatov, E. V. Prosekova, M. S. Dolgopolov, A. I. Turyanskaya, V. K. Kovalchuk, V. A. Sabynych

引用次数: 0

Variant anatomy of structures in Calot’s triangle 卡洛三角区结构的变异解剖学

Pacific Medical Journal Pub Date : 2024-05-18 DOI: 10.34215/1609-1175-2024-1-24-28

A. N. Shilova, T. Zharikova, K. R. Koychuev, Yury O Zharikov, V. Nikolenko

引用次数: 0

Decreased antioxidant capacity in children with diabetic ketoacidosis 糖尿病酮症酸中毒患儿抗氧化能力下降

Pacific Medical Journal Pub Date : 2024-05-18 DOI: 10.34215/1609-1175-2024-1-39-42

Yu. V. Bykov, V. Baturin, A. P. Vorobyova, A. A. Vartanyan

{"title":"Decreased antioxidant capacity in children with diabetic ketoacidosis","authors":"Yu. V. Bykov, V. Baturin, A. P. Vorobyova, A. A. Vartanyan","doi":"10.34215/1609-1175-2024-1-39-42","DOIUrl":"https://doi.org/10.34215/1609-1175-2024-1-39-42","url":null,"abstract":"Objective. To analyze the levels of antioxidant enzyme superoxide dismutase (SOD) and glutathione peroxidase (GP) against the background of diabetic ketoacidosis (DKA) in type 1 diabetes mellitus (DM) children and adolescents. Materials and methods. The study involved examination of 74 children: 50 DKA children (study group) and 24 relatively healthy children (control group). The study group children were divided into two subgroups: subgroup 1 included children with DKA against the background of type 1 DM onset (n=27), subgroup 2 consisted of children with DKA against the background of chronic type 1 DM (n=23). SOD and GP concentrations in blood plasma were determined in all children by enzyme immunoassay. The reliability between the data was estimated using the Mann-Whitney test, Kruskal-Wallis test and Spearman coefficient. Results. A significant decrease in SOD and GP in children with DKA was revealed as follows: 13130 [13005–18255] Pg/ml and 50.085 [42.02–70.325] Ng/ml, compared to controls: 16415 [13370–19935] Pg/ml and 84.695 [52.49–144.5] Ng/ml, respectively. Minimal SOD and GP were noted in patients with DKA at the background of chronic type 1 DM, compared to DM onset children. The study indicates a reliable correlation between age, duration of the disease, number of DKA in the history and low values of SOD and GP. Conclusion. Decreased antioxidant capacity was found in children with DKA in type 1 DM. SOD and GP can be considered in pediatric practice as markers of oxidative stress in DKA. In addition, an early detection of SOD and GP contributes to the efficient therapy of DKA in children and adolescents.","PeriodicalId":19705,"journal":{"name":"Pacific Medical Journal","volume":"124 46","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141125254","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Concentration of fatty acid binding protein as a new indicator of ejaculate fertility 脂肪酸结合蛋白浓度作为射精生育能力的新指标

Pacific Medical Journal Pub Date : 2024-05-18 DOI: 10.34215/1609-1175-2024-1-60-63

D. Sosnin, K. R. Galkovich

{"title":"Concentration of fatty acid binding protein as a new indicator of ejaculate fertility","authors":"D. Sosnin, K. R. Galkovich","doi":"10.34215/1609-1175-2024-1-60-63","DOIUrl":"https://doi.org/10.34215/1609-1175-2024-1-60-63","url":null,"abstract":"Objective. To determine the marker function of fatty acid binding protein (FABP) concentration in seminal plasma (SP) in order to assess ejaculate fertility used in in vitro fertilization (IVF) treatment of infertility in couples. Materials and methods. The study involved semen samples of 96 men of reproductive age: the study group (n=63) – patients with a decrease in concentration and/or total content of spermatozoa in ejaculate, the comparison group (n=33) – men with normal concentration and number of spermatozoa in ejaculate. The content of FABP in SP was determined by enzyme-linked immunosorbent assay using the test system “FABP – ELISA – BEST” (A-9102, Vector-Best, Russia). In order to determine the informative value of using the concentration of FABP in SP as a criterion of ejaculate fertility of men of the study group, the predictive value of positive and negative IVF results was determined by calculating the diagnostic sensitivity, specificity and efficiency. Results. The content of FABP in SP accounted for 1.29 ± 0.24 ng/mL, the median and interquartile range comprised 1.23 [1.13–1.35] ng/mL, ranging from 1.08 to 2.79 ng/mL. The study revealed statistically significant intergroup differences (Mann-Whitney test U=79.00; p=0.000016), a weak correlation between the level of FABP and the concentration of spermatozoa (R=0.578008) and their number in ejaculate (R=0.583599). The diagnostic sensitivity of the test for FABP in SP of the men of the study group accounted for 81.82%, specificity – 78.95%, efficiency – 80.95%. Conclusion. Seminal plasma FABP can act as a marker of spermatogenesis disorders. The study of this protein in ejaculate provides the accuracy of predicting the outcome of in vitro fertilization.","PeriodicalId":19705,"journal":{"name":"Pacific Medical Journal","volume":"116 51","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141125106","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0