{"title":"[Trunk deformity in scoliosis studied by surface measurement].","authors":"T Ono","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Ihe three-dimensional back surface shape of 504 patients with untreated idiopathic scoliosis was studied using moiré topography. A new system for the quantitative analysis of moiré pictures was developed with the aid of a still video photo system and microcomputer system. With these systems, the outcome of the analysis can be obtained immediately at the clinical scene. Using a positioning device that restrained the movement of the patient's pelvis at the time of taking the moiré picture, the reproducibility error was very small. The relationship of the parameters from the surface measurements with the radiographic appearance was then examined. The hump sum (HS), that is the sum total of the hump indices on three levels of the back was used as an index that represented the severity of the trunk deformity. It was possible to estimate objectively from HS, the correction in trunk deformity obtained after treatment. There was a relatively weak but statistically significant number of cases in which the degree of hump and that of the lateral curvature did not agree. Those within the range of one standard deviation from the regression line were defined as the standard rotation group, and those out of this range as the nonstandard rotation group. In the standard rotation group, the progression in curvature could be detected by moiré analysis so that exposure to radiation could be reduced. In the nonstandard rotation group, radiographic examination remained necessary, although the magnitude of the trunk deformity itself could be estimated more accurately by HS. The discrepancy between the HS and the Cobb angle suggested that scoliosis and rib deformity were independent from each other, and therefore they should be evaluated separately.</p>","PeriodicalId":19640,"journal":{"name":"Nihon Seikeigeka Gakkai zasshi","volume":"69 10","pages":"915-26"},"PeriodicalIF":0.0,"publicationDate":"1995-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"19532263","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[A chronic spinal cord compression model in a rat with a 354A tumor].","authors":"M Izumida","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>A posterior spinal cord compression model was produced in a rat with a 354 A tumor. Here we report the compression process using MRI (at 2.11 tesla), the progression of paralysis in the posterior limbs, the pathological changes in the neural tissues, and the spinal evoked potentials (SpEPs). A relatively flat spinal cord compression model was established by the interposition of free fatty tissue between the tumor and dura mater. The anteroposterior diameter of the compressed cord (AP), the width of the compressed cord (W), the cross-sectional areas of the spine (A), the mean of the anteroposterior diameters of the cord at the levels of the adjacent cephalic and caudal vertebral bodies (AP), and the mean of the cross-sectional areas of the cord at the levels of the adjacent cephalic and caudal vertebral bodies (A) were measured on axial views from MRI. Paralysis of the posterior limbs occurred in this model when A/A became less than 60%, AP/AP became less than 35% and AP/W became less than 20%. Pathological changes became apparent in the neural tissues when A/A became less than 50-60%, AP/AP became less than 25-30% and AP/W became less than 15%. Polyphasic wave-forms were noted when A/A became less than 60%, AP/AP became less than 35% and AP/W became less than 20%. When the A/A became less than 40%, the histopathological changes became marked. SpEPs could no longer be detected at this degree of compression, indicating that all neural conduction had been blocked.</p>","PeriodicalId":19640,"journal":{"name":"Nihon Seikeigeka Gakkai zasshi","volume":"69 10","pages":"977-91"},"PeriodicalIF":0.0,"publicationDate":"1995-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"19530930","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[A comparative study between magnetic resonance imaging and histological findings of bone and soft tissue tumors].","authors":"K Itoh","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Diagnostic methodology for bone and soft tissue tumors has made great strides recently through the development of magnetic resonance imaging (MRI). Here we report a comparative assessment of the histological findings of bone and soft tissue tumors with MRI from 212 cases. The accuracy of a qualitative diagnosis was observed in a solitary bone cyst, enchondroma, giant cell tumor, chondrosarcoma, lipoma, hemangioma, neurinoma, and in a synovial cyst. However, the qualitative diagnosis of a malignant tumor was difficult because of the variety of the intratumoral histological changes. An enhanced-image using Gd-DTPA was useful for differentiation of the viable region in the internal area of a tumor, discrimination of the rective zone of an edema or assessing vascularity, and for discrimination between a cyst and a solid tumor. Based on comparison with findings from the excised specimen, it was found that histological changes such as calcification, fibrosis, hemorrhaging and necrosis, and the presence or absence of a tumor capsule had been reflected accurately on MR images. However, infiltration of the tumor into the bone cortex and into the articular cartilage were found frequently to be false-positive on MRI. Although problems remained to be solved regarding the evaluation of the presence or absence of tumor infiltration into adjacent tissue, the depiction of periosteal reaction, and regarding differentiation from inflammatory disease, MRI was a very useful information source for operative planning because it could evaluate the relationship between the tumor and adjacent blood vessels or nerves, the effect of preoperative therapy, and effectively discriminate between benign and malignant tumors.</p>","PeriodicalId":19640,"journal":{"name":"Nihon Seikeigeka Gakkai zasshi","volume":"69 10","pages":"899-914"},"PeriodicalIF":0.0,"publicationDate":"1995-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"19532262","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Y Kuroki, K Hirakawa, J Hayashi, Y Imazato, M Hirakawa
{"title":"[Mechanism of the radiolucence around the implant after hip prosthetic replacement].","authors":"Y Kuroki, K Hirakawa, J Hayashi, Y Imazato, M Hirakawa","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>After hip prosthetic replacement, a progressive enlargement in the radiolucent area has often been observed around the implant, leading to loosening of the prosthesis. The purpose of this study was to investigate the mechanism of the radiolucent area formation. Radiolucent areas can be classified into either linear type or the erosive type, and these two types were compared histologically and biochemically. Interface membranes were obtained from patients at the time of surgery for revision of either cemented THA or cementless bipolar endprosthetic replacement. Histological specimens were stained by H.E., tartrate-resistant acid phosphate, and by the immunohistochemical reagents anti-macrophage antibody (CD 68), anti-T-lymphocyte (CD 3, CD 4, CD 8, CD 43), anti-interleukin-1 beta polyclonal antibody, anti-interleukin-6 polyclonal antibody, and anti-tumor necrosis factor-alpha polyclonal antibody. Biochemically, interleukin-1 beta, IL-6, IL-8, TNF-alpha were assayed by ELISA in the supernatant of homogenized samples and in organ culture media. Prostaglandin E2 was assayed by radioimmunoassay. The interfaces of the erosive type contained more debris (cement, high density polyethylene and metal), macrophages and multinucleated giant cells than the linear type. The interfaces of the linear type showed mainly fibrosis and necrosis. The levels of IL-6 and IL-8 in the homogenates and culture media from the erosive type were significantly higher than those from the linear type. We concluded that the bone resorption around the implant after hip prosthetic replacement occurred by two different pathways. One pathway involved the stimulation of macrophages by various debris and micromovement to form foreign body granulomas, which produced cytokines, prostaglandin E2 and metalloproteinase to resorb bone. The erosive type would arise from this pathway. The other possible mechanism involved a biomechanically unstable implant which caused bone necrosis probably by mechanical stress. The linear type may arise from this pathway.</p>","PeriodicalId":19640,"journal":{"name":"Nihon Seikeigeka Gakkai zasshi","volume":"69 10","pages":"927-37"},"PeriodicalIF":0.0,"publicationDate":"1995-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"19532264","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Somatosensory evoked potentials for the diagnosis of carpal tunnel syndrome].","authors":"M Kawasaki, T Saito, R Ogawa","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The middle latency somatosensory evoked potential (SEP), in particular the N60 of median nerve SEP, can be recorded in patients with severe peripheral neuropathy even in the absence of a recordable compound muscle action potential (CMAP). However, clinical utilization of N60 is hampered by its inter-trial variabilities that depend on the level of consciousness, habituation, stimulus rate and/or other unknown factors. We have now obtained a stable N60 SEP when the subject stays awake and alert using a slow stimulus rate. We have applied this method to 17 hands of 15 patients with severe carpal tunnel syndrome (CaTS) whose CMAP were not recordable. The stimuli were applied to two sites: one was 2 cm proximal to the distal crease at the wrist and the other was on the middle finger. SEP were recorded from a central electrode contralateral to the side of stimulation and referenced to the bilateral ear. In normal subjects, the estimated conduction velocities between the distal crease and the middle finger measured by the N60 latency difference ranged from 45.1 to 89.2 m/sec with a mean velocity of 67.4 +/- 13.0 m/sec. In 12 CaTS hands, the stimulation of the fingers resulted in a significantly delayed N60 (8 hands) or no response (4 hands). The estimated conduction velocity in CaTS ranged from 9.3 to 21.2 m/sec with mean velocity of 15.6 +/- 4.2 m/sec. In order to localize the point of maximal conduction delay in the CaTS, a further 17 hands were examined by stimulation of the median nerve at multiple sites across the carpal tunnel.(ABSTRACT TRUNCATED AT 250 WORDS)</p>","PeriodicalId":19640,"journal":{"name":"Nihon Seikeigeka Gakkai zasshi","volume":"69 10","pages":"891-8"},"PeriodicalIF":0.0,"publicationDate":"1995-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"19532261","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Histological changes, muscle force and fatigability after electrical stimulation to experimentally paralyzed muscles].","authors":"M Oba","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>In order to use functional electrical stimulation effectively in paralyzed muscle treatment, changes in the maximal muscle force, muscle fatigue, and histological changes were evaluated in electrically stimulated muscles. Study 1. Tissue damage by percutaneous intramuscular electrodes implanted into the quadriceps muscle was examined in rat. Stimulation was conducted at various output voltages, and for various durations of time, in order to assess the histological changes in the muscle around the electrodes. Study 2. Electrodes were implanted into the bilateral quadriceps and gastrocnemius muscles of adult cat, and the unilateral muscles were then stimulated from 3 weeks following the transection of the spinal cord at the T9 level. Stimulus parameters were divided into two groups; as \"A\" stimulation: at -8V for 15min twice/week, and as \"B\" stimulation: at -16V for 30 min 4 times/week. The histological changes were examined using the myofibrillar ATPase method to determine the diameters and occupation ratios for each muscle fiber type. RESULTS. Study 1. Significant tissue damage began to occur when the voltage output created the maximum muscle contraction force. Until that critical voltage point was reached, tissue damage was not significant, regardless of the duration of the stimulation. Study 2. The maximum muscle force decreased until 4 weeks after the transection, then increased regardless of the presence of electrical stimulation. The muscle fatigability of the non-stimulated muscle was greater than that of the stimulated muscle. High voltage, long duration, and frequent stimulation was effective in controlling fatigue. The ratio of type I fibers was higher in the stimulated muscle. There was no evidence, however, of suppressing muscle fiber atrophy after electrical stimulation. These results suggested that electrically stimulating paralyzed muscles was effective for suppressing muscle fatigue, and for reducing the ratio of type I fibers. In clinical use, the output voltage should be kept below the voltage that induces the maximum muscle contraction to prevent tissue damage.</p>","PeriodicalId":19640,"journal":{"name":"Nihon Seikeigeka Gakkai zasshi","volume":"69 9","pages":"708-20"},"PeriodicalIF":0.0,"publicationDate":"1995-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"19511236","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Retinoic acid-induced hyperostosis in the murine spine, particularly in the cervical spine].","authors":"T Kudo","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>In order to investigate the role of retinoic acid in inducing spinal hyperostosis, the murine spine was radiologically and histologically examined after a 24-week peroral administration of synthetic retinoic acid (etretinate). In the cervical spine, osteophytes on the ventral rims of the vertebral bodies were more developed after etretinate administration than in controls. Histologically, chondrocytes after etretinate administration proliferated in the anterior longitudinal ligaments at the junction of the ventro-caudal rim and the epiphyseal region of the C2 and C3 vertebral bodies. Endochondral ossification was a characteristic feature and immature chondrocytes and mesenchymal cells were found in the region. After etretinate administration, the incidence of proliferative changes was 67.6% at the C2 ventro-caudal rim, and 79.4% and 70.6%, respectively in the C2 and C3 ventral epiphyseal regions. These percentages were highly significant compared with controls, but they were not dosage-dependent. These findings suggested that retinoic acid was involved in the differentiation and proliferation of chondrocytes in ligaments.</p>","PeriodicalId":19640,"journal":{"name":"Nihon Seikeigeka Gakkai zasshi","volume":"69 9","pages":"744-53"},"PeriodicalIF":0.0,"publicationDate":"1995-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"19511239","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Changes in the visco-elastic properties of the articular cartilage incubated in various kinds of liquid].","authors":"T Nishimoto","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The purpose of our experiment was to investigate the way in which the visco-elastic properties of the articular cartilage of a loading joint responded to various liquid environments. Using articular cartilage extracted from the femoral head of a cow, we examined the viscoelasticity of the articular cartilage under a fixed load while it was immersed in distilled water, isotonic salt water, hypertonic salt water, and in hyaluronic acid. A stainless steel rod with a diameter of 1.5 mm was applied directly to the articular cartilage (weighing 25, 50 and 100 grams) and the resultant visco-elastic curves were measured. Results showed that the deformation change to the cartilage was greatest while it was immersed in hypertonic salt solution and smallest while immersed in distilled water. Secondly, when immersed in hyaluronic acid solution, the change in deformation proved to be greater when the solution was denser and the molecular weight heavier and the hyaluronic acid could not penetrate into the cartilage matrix and remained at the surface. These results demonstrated that the visco-elastic property of the articular cartilage was affected not only by the varying osmotic pressures on the internal parts of the cartilage, but also on the density of the solution surrounding the cartilage and on the different water retainability of that cartilage.</p>","PeriodicalId":19640,"journal":{"name":"Nihon Seikeigeka Gakkai zasshi","volume":"69 9","pages":"776-87"},"PeriodicalIF":0.0,"publicationDate":"1995-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"19513186","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Effects of prostaglandin E2 and sodium hyaluronate on bradykinin induced knee joint pain in rat].","authors":"I Yamashita, Y Atsuta, S Shimazaki, M Miyatsu","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>We studied effects of prostaglandin E2 and sodium hyaluronate on the reactive muscle activity induced by intra-articular injection of bradykinin into the knee joint of rat. An animal model was developed to evaluate knee joint pain. In unanesthetized and spinalized rat, bradykinin (BK) was injected into the knee joint and the duration of the reactive activity of the knee flexor was evaluated. The duration of the reaction was elongated dependent on the injected BK dosage (0.025-2.5 micrograms). When prostaglandin E2 (PG E2) was injected with BK, the duration of the reaction increased significantly (p < 0.01). In contrast, sodium hyaluronate (Na-HA: average MW 900 kD) injected into the joint 3-24 hours in advance significantly inhibited the BK induced reaction (p < 0.05-0.01). A histological study demonstrated the fluorescein-labeled Na-HA diffusely infiltrating into the surface of the soft tissue. From these results, the animal model used in the present study was valuable to evaluate quantitatively knee joint pain. Furthermore, the sensitizing effect of PG E2 and the inhibitory effect of Na-HA on joint pain was objectively demonstrated.</p>","PeriodicalId":19640,"journal":{"name":"Nihon Seikeigeka Gakkai zasshi","volume":"69 9","pages":"735-43"},"PeriodicalIF":0.0,"publicationDate":"1995-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"19511238","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[An experimental study on recovery of lacerated skeletal muscle: correlation between separation gap and the potential for recovery].","authors":"N Terada","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Skeletal muscle has a potential for recovery with muscle tissue when the lacerated stumps are maintained in contact. However, when there is no contact, this potential for recovery is unknown. Here we report our studies on the correlation between the recovery and the separation distance between the stumps in partially lacerated muscles in Wistar rat. The gastrocnemius muscle was subjected to a partial wedge-shaped laceration which allowed the surrounding tissue to hold a constant separation distance between the stumps throughout the duration of the study. Groups each of 7 rats were examined at 1, 2, and at 4 days, and at 1, 2, 2, and at 6 weeks after the laceration was performed. In each group, 5 rats underwent histological and immunohistological examinations, while the other 2 underwent electronmicroscopic examination. The muscle stumps initially degenerated, and then began to regenerate at 4 days after the laceration. During this period, local basement membranes remained intact allowing regeneration of muscle fibers. However, the absence of basement membrane between the stumps led to a random regeneration pattern of myotubes growing into the granulation tissue in the wedge-shaped gap. The electronmicroscopic findings showed that these growing myotubes had no basement membrane. The maximum growth of these myotubes was found to be 1.20 +/- 0.31 mm reached at 3 weeks after the laceration, suggesting that the maximum gap was approximately 1.0 mm across which there is a potential for recovery through regeneration.</p>","PeriodicalId":19640,"journal":{"name":"Nihon Seikeigeka Gakkai zasshi","volume":"69 9","pages":"754-66"},"PeriodicalIF":0.0,"publicationDate":"1995-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"19511240","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}