{"title":"Lethal infection of C57BL mouse with bovid herpesvirus 1.","authors":"K Okazaki, K Nakatsu, E Honda, T Kumagai","doi":"10.1292/jvms1939.52.1093","DOIUrl":"https://doi.org/10.1292/jvms1939.52.1093","url":null,"abstract":"","PeriodicalId":19620,"journal":{"name":"Nihon juigaku zasshi. The Japanese journal of veterinary science","volume":"52 5","pages":"1093-5"},"PeriodicalIF":0.0,"publicationDate":"1990-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1292/jvms1939.52.1093","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13330396","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"An evaluation of the syncytial assay for detection of bovine immunodeficiency-like virus.","authors":"M Onuma, Y Ogawa, Y Kawakami","doi":"10.1292/jvms1939.52.1131","DOIUrl":"https://doi.org/10.1292/jvms1939.52.1131","url":null,"abstract":"","PeriodicalId":19620,"journal":{"name":"Nihon juigaku zasshi. The Japanese journal of veterinary science","volume":"52 5","pages":"1131-3"},"PeriodicalIF":0.0,"publicationDate":"1990-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1292/jvms1939.52.1131","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13330399","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Immunosuppressive effect of infectious pancreatic necrosis virus on rainbow trout (Oncorhynchus mykiss).","authors":"H Tate, H Kodama, H Izawa","doi":"10.1292/jvms1939.52.931","DOIUrl":"https://doi.org/10.1292/jvms1939.52.931","url":null,"abstract":"<p><p>The infectivity of infectious pancreatic necrosis virus (IPNV) for rainbow trout (Oncorhynchus mykiss) mononuclear leukocyte subpopulations was investigated to determine the mechanisms of immunosuppression caused by the virus. IPNV was recovered from nylon wool-adherent, surface immunoglobulin (Ig)-positive leukocytes of head kidney, spleen and peripheral blood collected from virus-inoculated fish with higher titers than non-adherent, Ig-negative cells. Non-adherent cell population showed mitogenic response to phytohemagglutinin and concanavalin A but not to lipopolysaccharide. Conversely, the responses of adherent cells to these mitogens were weak. Mitogenic response and non-specific cytotoxicity of head kidney leukocytes significantly decreased by the inoculation of fish with the virus. These results suggest that the suppression of immune responses is involved in the establishment of carrier state in fish after infection with IPNV.</p>","PeriodicalId":19620,"journal":{"name":"Nihon juigaku zasshi. The Japanese journal of veterinary science","volume":"52 5","pages":"931-7"},"PeriodicalIF":0.0,"publicationDate":"1990-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1292/jvms1939.52.931","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13330402","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
M Okamoto, M Kamiya, Y Oku, M Ohbayashi, T Matsuzaki
{"title":"Low susceptibility of the laboratory-reared Afghan pika, Ochotona rufescens rufescens to Haemonchus contortus.","authors":"M Okamoto, M Kamiya, Y Oku, M Ohbayashi, T Matsuzaki","doi":"10.1292/jvms1939.52.1107","DOIUrl":"https://doi.org/10.1292/jvms1939.52.1107","url":null,"abstract":"","PeriodicalId":19620,"journal":{"name":"Nihon juigaku zasshi. The Japanese journal of veterinary science","volume":"52 5","pages":"1107-8"},"PeriodicalIF":0.0,"publicationDate":"1990-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1292/jvms1939.52.1107","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13430820","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Prevalence and characterization of Pasteurella multocida in rabbits and their environment in Japan.","authors":"E Kawamoto, T Sawada, T Maruyama","doi":"10.1292/jvms1939.52.915","DOIUrl":"https://doi.org/10.1292/jvms1939.52.915","url":null,"abstract":"<p><p>Prevalence and some properties of Pasteurella multocida in rabbits kept at laboratory animal facilities and commercial rabbitries, and in their environment were investigated. A total of 1,147 nasal swab samples from 1,147 rabbits and 126 samples from their environment were subjected to the isolation of P. multocida. The bacteria were isolated from 199 (29.8%) of 668 rabbits in laboratory animal facilities and from 1 (0.2%) of 479 rabbits in the rabbitries. Isolation rate of P. multocida was low (0.9%) or high (44.9%) in the facilities with or without the monitoring for the presence of the bacteria, respectively. The highest rate of the isolation from rabbits was recorded at 10 to 12 months of their housing time. Thirty-nine cultures (31.0%) of air and the surfaces of floors, tips of water bottles, and cages were positive for P. multocida and isolation rate of the bacteria was high (78.6%) in the air. Biological and biochemical properties of the isolates were identical except for indole production and raffinose fermentation. The isolates were susceptible to antibiotics tested except for clindamycin, serologically similar in the gel-diffusion precipitin test and weakly virulent for mice. The present results suggested that these P. multocida isolates were the causal agent of rabbits rhinitis (snuffles) in Japan.</p>","PeriodicalId":19620,"journal":{"name":"Nihon juigaku zasshi. The Japanese journal of veterinary science","volume":"52 5","pages":"915-21"},"PeriodicalIF":0.0,"publicationDate":"1990-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1292/jvms1939.52.915","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13430825","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Biological effects of leptospiral lipopolysaccharide to mouse B, T and NK cells.","authors":"E Isogai, H Isogai, N Fujii, K Oguma","doi":"10.1292/jvms1939.52.923","DOIUrl":"https://doi.org/10.1292/jvms1939.52.923","url":null,"abstract":"Leptospiral lipopolysaccharides (LPSs) extracted from Leptospira interrogans serovars copenhageni and hebdomadis were tested for the biological effect to mouse B, T and NK cells. Each leptospiral LPS was a potent mitogen for spleen B cells. Activation of the cells was also expressed by polyclonal B cell activation. In contrast, mitogenicity for T cells, induction of interleukin-2 (IL-2) secretion in T cells and increase of tumor-killing activity and chemiluminescence in NK cells were not observed after stimulation with leptospiral LPS. After intravenous injection of leptospiral LPS in mice, the spleen and lymphnodes were examined by histocytochemical technique. Increase of Ig-bearing lymphocytes was recognized while decrease of T cells was observed in the lymphoid organs. Mitogenic response to PHA, Con A and PWM decreased with relation to the T cell depletion. In conclusion, it is apparent that leptospiral LPS possess marked immunological potencies on B cells but not T and NK cells. The biological effects of leptospiral LPS were common ones as LPS but the level was considered to be different from classical LPS such as Escherichia coli LPS.","PeriodicalId":19620,"journal":{"name":"Nihon juigaku zasshi. The Japanese journal of veterinary science","volume":"52 5","pages":"923-30"},"PeriodicalIF":0.0,"publicationDate":"1990-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1292/jvms1939.52.923","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13430826","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Cysteine protease in bovine milk capable of hydrolyzing casein as the substrate and elevation of the activity during the course of mastitis.","authors":"J Suzuki, N Katoh","doi":"10.1292/jvms1939.52.947","DOIUrl":"https://doi.org/10.1292/jvms1939.52.947","url":null,"abstract":"<p><p>Cysteine protease was found to be present in bovine milk that catalyzed casein as the substrate. The protease was activated by reducing agents such as 2-mercaptoethanol and inhibited by monoiodoacetic acid, but not affected by the addition of phenylmethylsulfonyl fluoride, calcium or ethylene glycol bis (beta-aminoethyl)-N,N,N',N'-tetraacetic acid. The protease activity was linear as a function of protein amount and incubation time, and showed maximum at pH 6.0. By Sephacryl S-200 chromatography, at least two types of cysteine proteases having molecular weights of 45 kDa and more than 150 kDa were detected. The activity was increased in mastitic milk, and well correlated with the stages of mastitis, as indicated by the California mastitis test, somatic cell count and protein concentration. These results suggested that cysteine protease(s) is involved in the pathogenesis of mastitis.</p>","PeriodicalId":19620,"journal":{"name":"Nihon juigaku zasshi. The Japanese journal of veterinary science","volume":"52 5","pages":"947-54"},"PeriodicalIF":0.0,"publicationDate":"1990-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1292/jvms1939.52.947","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13431578","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
T Hasegawa, K Matsuoka, K Ono, T Watari, R Goitsuka, R Nishimura, H Nakayama, N Goto, A Hasegawa
{"title":"Immune mediated skin lesions in a dog with autoimmune hemolytic anemia.","authors":"T Hasegawa, K Matsuoka, K Ono, T Watari, R Goitsuka, R Nishimura, H Nakayama, N Goto, A Hasegawa","doi":"10.1292/jvms1939.52.1001","DOIUrl":"https://doi.org/10.1292/jvms1939.52.1001","url":null,"abstract":"<p><p>A canine case of Coombs' test positive and antinuclear antibody-negative hemolytic anemia was examined because of the development of skin lesions after 18 months treatment with prednisolone. Histopathological examination of biopsy specimens obtained from skin and oral mucosa revealed the acantholysis, edematous lesions of the stratum basale and mononuclear cell accumulation in the dermis. Deposits of immunoglobulin G and complement factor 3 were detected at the intercellular and dermoepidermal junction by the direct immunofluorescent test. From these results, the case was considered to be an autoimmune disease caused by distinct antibodies against different organs.</p>","PeriodicalId":19620,"journal":{"name":"Nihon juigaku zasshi. The Japanese journal of veterinary science","volume":"52 5","pages":"1001-6"},"PeriodicalIF":0.0,"publicationDate":"1990-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1292/jvms1939.52.1001","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13430989","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Antigenic identification of excretory-secretory products of adult Dirofilaria immitis.","authors":"H Kaneko, M Hayasaki, I Ohishi","doi":"10.1292/jvms1939.52.995","DOIUrl":"https://doi.org/10.1292/jvms1939.52.995","url":null,"abstract":"<p><p>Excretory-secretory (ES) products collected from adult Dirofilaria immitis cultured in vitro were analyzed by sodium dodecyl sulfate polyacrylamide gel electrophoresis (SDS-PAGE) and immunoblotting. ES products of male (M-ES) and female (F-ES) worms were separated into 16 and 21 bands by SDS-PAGE with Coomassie blue and silver staining, respectively. The antigenic bands were then analyzed by immunoblotting, using pooled sera from dogs that had naturally contracted D. immitis. Sera from dogs with microfilaremic infection showed 7 bands in M-ES and 10 bands in F-ES, while those from dogs with occult infection revealed 3 bands in M-ES and 10 bands in F-ES. Among these bands, those of 14, 18, 21, 22, 29, and 32 kilodaltons (Kd) were common to M-ES and F-ES, those of 39 and 44 Kd were specific to M-ES, and those of 20, 38, 43, 53, 63, 90, 110, 125 and 136 Kd were specific to F-ES.</p>","PeriodicalId":19620,"journal":{"name":"Nihon juigaku zasshi. The Japanese journal of veterinary science","volume":"52 5","pages":"995-1000"},"PeriodicalIF":0.0,"publicationDate":"1990-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1292/jvms1939.52.995","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13431584","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
N Hirayama, E Raharjo Jusa, M Aeny Rochman Noor, K Sakaki, M Ogata
{"title":"Immune state of dogs injected with rabies vaccines in the west Java, Indonesia.","authors":"N Hirayama, E Raharjo Jusa, M Aeny Rochman Noor, K Sakaki, M Ogata","doi":"10.1292/jvms1939.52.1099","DOIUrl":"https://doi.org/10.1292/jvms1939.52.1099","url":null,"abstract":"","PeriodicalId":19620,"journal":{"name":"Nihon juigaku zasshi. The Japanese journal of veterinary science","volume":"52 5","pages":"1099-101"},"PeriodicalIF":0.0,"publicationDate":"1990-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1292/jvms1939.52.1099","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13430818","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}