Nusantara Bioscience最新文献

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Short communication: Effects of Canarium indicum oil in enhancing brain-derived neurotrophic factor in rats 短通讯:印度金丝雀油增强大鼠脑源性神经营养因子的作用
IF 0.4
Nusantara Bioscience Pub Date : 2020-11-12 DOI: 10.13057/nusbiosci/n120213
H. Rahman, K. Anggadiredja, T. Gusdinar, J. Sitompul, Tursino Tursino
{"title":"Short communication: Effects of Canarium indicum oil in enhancing brain-derived neurotrophic factor in rats","authors":"H. Rahman, K. Anggadiredja, T. Gusdinar, J. Sitompul, Tursino Tursino","doi":"10.13057/nusbiosci/n120213","DOIUrl":"https://doi.org/10.13057/nusbiosci/n120213","url":null,"abstract":"Rahman H, Anggadiredja K, Gusdinar T, Sitompul JP, Tursino. 2020. Short communication: Effects of Canarium indicum oil in enhancing brain-derived neurotrophic factor in rats. Nusantara Bioscience 12: 168-174. The brain-derived neurotrophic factor (BDNF) is one of the neurotrophins family and plays an essential role during the development of neurons called neurogenesis. Since BDNF is critical for the function and survival of neurons, thus it represents the neuroprotective agent which useful in preventing neurodegenerative diseases. Here, we investigated BDNF serum concentrations after feeding the canarium oil (CO) and Canarium oilbased structured triglyceride (COST) in rats. Analysis of the BDNF serum was conducted by sandwich enzyme-linked immunosorbent assay (ELISA). The results demonstrated that the CO and the COST with the main composition of unsaturated fatty acids at the sn-2 position as much as 94.92% mol may enhance BDNF serum concentrations of up to 2.66% and 21.96% compared to the normal group of rats, respectively. This finding proves that the COST has prospects as an inducer of BDNF. However, further studies should be conducted to identify the precise dosage and safety products.","PeriodicalId":19481,"journal":{"name":"Nusantara Bioscience","volume":null,"pages":null},"PeriodicalIF":0.4,"publicationDate":"2020-11-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47322521","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Golden apple snail (Pomacea canaliculata) as an alternative protein source in Pasupati catfish (Pangasius sp.) fish feed 金苹果蜗牛(Pomacea canalillata)作为帕苏帕蒂鲶鱼(Pangasius sp.)鱼类饲料的替代蛋白质来源
IF 0.4
Nusantara Bioscience Pub Date : 2020-11-11 DOI: 10.13057/nusbiosci/n120212
M. P. Pertiwi, D. Saputri
{"title":"Golden apple snail (Pomacea canaliculata) as an alternative protein source in Pasupati catfish (Pangasius sp.) fish feed","authors":"M. P. Pertiwi, D. Saputri","doi":"10.13057/nusbiosci/n120212","DOIUrl":"https://doi.org/10.13057/nusbiosci/n120212","url":null,"abstract":"Pertiwi MP, Saputri DD. 2020. Golden apple snail (Pomacea canaliculata) as an alternative protein source in Pasupati catfish (Pangasius sp.) fish feed. Nusantara Bioscience 12: 162-167. Research on efforts to conserve golden apple snail (Pomacea canaliculata) meat has been done. This research aimed to utilize the snail meat as an alternative feed for the Pasupati catfish (Pangasius sp.). The research was carried out from May to August 2020. It began by collecting Pomacea canaliculata by hand sorting then processed into artificial feed/pellets. The research was CRD designed with 5 treatments and 3 replications. Pasupati catfish juvenil measuring 7.4 ± 0.8 cm and weighing 11.7 ± 0.5 g, was maintained for 21 days with a stocking density of 15 individuals/aquarium. Feeding as much as 8% of the biomass with a frequency of feeding 3 times a day at satiation. Variables measured were SGR, L, RP, FCR, and SR. The results showed that feed B produced the best fish growth and could be an alternative fish feed without having a negative effect on growth and feed utilization. Feed B (90% fish meal + 10% Pomacea canaliculata meat meal) had the highest SGR value and was supported by a high PR value and a low FCR value. In addition, there is a difference among variables, despite least significant. ANOVA test also supports the differences between treatments, but HSD test (p<0,05) is not significantly different. This means that the addition of the percentage of P. canaliculata meat meal to the feed does not provide a good performance of the Pasupati catfish. Value of abiotic parameters was to support fish farming.","PeriodicalId":19481,"journal":{"name":"Nusantara Bioscience","volume":null,"pages":null},"PeriodicalIF":0.4,"publicationDate":"2020-11-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43454655","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
Biological responses of Sri Lankan rice (Oryza sativa L.) varieties to rhythmic sound patterns (music and religious chants) 斯里兰卡水稻(Oryza sativa L.)品种对有节奏的声音模式(音乐和宗教圣歌)的生物反应
IF 0.4
Nusantara Bioscience Pub Date : 2020-11-09 DOI: 10.13057/nusbiosci/n120211
S. Munasinghe, S. Weerakoon, S. Somaratne
{"title":"Biological responses of Sri Lankan rice (Oryza sativa L.) varieties to rhythmic sound patterns (music and religious chants)","authors":"S. Munasinghe, S. Weerakoon, S. Somaratne","doi":"10.13057/nusbiosci/n120211","DOIUrl":"https://doi.org/10.13057/nusbiosci/n120211","url":null,"abstract":"Munasinghe DSP, Weerakoon SR, Somaratne S. 2020. Biological responses of Sri Lankan rice (Oryza sativa L.) varieties to rhythmic sound patterns (music and religious chants). Nusantara Bioscience 12: 154-161. Influences of music cause either promoting or restricting the growth of plants. The effects of Pirith chanting and rhythmic sound patterns (Western classical music, Eastern classical music, Rock music) were focused in the present study. Seeds of Two (02) rice varieties (Bg 300 and Kuruluthuda) in f0 and f1 generations were subjected to dormancy break treatment, kept in a soundproof confined chamber, and arranged in Randomized Complete Block Design (RCBD) with two (02) replicates and 10 seeds per replicate. Seeds were germinated under the three sound rhythms, Pirith chanting, and silence. Plants kept under silence served as the control. Sound rhythms and Pirith were played separately for an hour, at 30 cm distance away from the seeds with an intensity of 55-60 dB for seven (07) days continuously, maintaining equal environmental conditions. Following seven (07) days, the percentile germination rate was recorded. Germinated seeds were planted in plastic pots filled with paddy soil, up to 3⁄4 of the total depth, and pots were arranged in Randomized Complete Block Design (RCBD) with five (05) replicates and three (03) plants per replicate. Following one week, plants were subjected to sound rhythm treatments and silence for three (03) months continuously. Measurement of growth and yield performance were recorded every fortnight. Significantly different (p < 0.05) growth and yield performances in both generations were observed under Pirith, Eastern Classical and Western Classical music. Higher rates of growth were observed for rice varieties exposed to Pirith, Eastern and Western classical music. Similarly, yield was also higher compared to rice varieties exposed to rock music. The findings suggest that soft rhythmic sounds are the most appropriate type of music which improved growth and yield performance of rice varieties, Bg 300, and Kuruluthuda. However, further studies are needed to confirm present results and to elucidate the mechanism of responses to Pirith chanting and other rhythmic sound patterns using phytochemical and biochemical analyses.","PeriodicalId":19481,"journal":{"name":"Nusantara Bioscience","volume":null,"pages":null},"PeriodicalIF":0.4,"publicationDate":"2020-11-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47309790","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Larval development of nypa palm worm Namalycastis rhodochorde (Polychaeta: Nereididae) nypa棕榈虫Namalycastis rhodochorde的幼虫发育(Polychaeta:Nereidae)
IF 0.4
Nusantara Bioscience Pub Date : 2020-11-04 DOI: 10.13057/nusbiosci/n120210
Junardi Junardi, Tjandra Anggraeni, A. Ridwan, E. Yuwono
{"title":"Larval development of nypa palm worm Namalycastis rhodochorde (Polychaeta: Nereididae)","authors":"Junardi Junardi, Tjandra Anggraeni, A. Ridwan, E. Yuwono","doi":"10.13057/nusbiosci/n120210","DOIUrl":"https://doi.org/10.13057/nusbiosci/n120210","url":null,"abstract":"Abstract. Junardi, Anggraeni T, Ridwan A, Yowono E. 2020. Larval development of nypa palm worm Namalycastis rhodochorde (Polychaeta: Nereididae). Nusantara Bioscience 12: 148-153. Namalycastis intensive culture is still facing problems in mass production due to limited information on reproduction, especially in fertilization and production of larvae. The present research was designated to find out optimum salinity for fertilization and the production of nypa palm worm larvae (Namalycastis rhodochorde). Gamete samples were collected using a capillary glass tube inserted into ventro-lateral part of a body segment of a mature worm. Artificial fertilization was done by mixing the sperms and oocytes in a fertilization dish containing sterilized seawater as the medium. The larval development was observed until the benthic phase larvae (3-setigers). Fertilization was performed in medium salinity of 7-21‰ and water temperature of 25-29°C. The cleavage and larva stage occurred respectively within 28.20 to 58.67 minutes and within 72 to 80 hours after fertilization. The fertilization and larval development of N. rhodochorde were highly influenced by the medium salinity and temperature.","PeriodicalId":19481,"journal":{"name":"Nusantara Bioscience","volume":null,"pages":null},"PeriodicalIF":0.4,"publicationDate":"2020-11-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46097733","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
Organic fertilizer applications improve the growth of vegetable crops and chemical properties in the tailings deposition area at Timika, Papua, Indonesia 有机肥料的应用改善了印度尼西亚巴布亚Timika尾矿沉积区蔬菜作物的生长和化学特性
IF 0.4
Nusantara Bioscience Pub Date : 2020-10-20 DOI: 10.13057/nusbiosci/n120208
S. Taberima, S. Prabawardani, R. Sarwom, G. Lyons
{"title":"Organic fertilizer applications improve the growth of vegetable crops and chemical properties in the tailings deposition area at Timika, Papua, Indonesia","authors":"S. Taberima, S. Prabawardani, R. Sarwom, G. Lyons","doi":"10.13057/nusbiosci/n120208","DOIUrl":"https://doi.org/10.13057/nusbiosci/n120208","url":null,"abstract":"Taberima S, Prabawardani S, Sarwom R, Lyons G. 2020. Organic fertilizer applications improve the growth of vegetable crops and chemical properties in the tailings deposition area at Timika, Papua, Indonesia. Nusantara Bioscience 12: 134-142. This study aimed to observe growth responses of selected vegetable crops grown in the media of inactive tailings, the available nutrients (macro and microelements) in fresh tailings before and after planting, as well as the metal uptake by plant tissues. Research was conducted using Randomized Block Design with three treatments of organic matter (chicken manure, cow manure, and compost of Salvinia natans) to observe the response on growth and yield of kangkong, red spinach, tomato, and chili. Based on the geochemical data, the ratio of ANC/MPA ranged from 3.81 (0-20 cm) to 4.60 (20-40 cm). There was no acid potential, with ANC ratio > 1.5 x MPA, and this result was supported by soil pH, which was alkaline in both depths of tailings media, ranging from 7.94 (0-20 cm) to 7.90 (20-40 cm). There was no significant effect on the chemical properties in the first period before and after planting for three months of planting period, except for the application with organic fertilizers. The best organic fertilizers applied in fresh tailings were chicken manure, followed by the compost of S. natans and cow manure. These organic fertilizers produced good growth and yield components of kangkong, red spinach, tomato, and chili. Meanwhile, the lowest growth and yield response of these crops was shown by control (without compost or manure). The level of metal uptake by all vegetables was low, suggesting that these vegetables are safe to be consumed.","PeriodicalId":19481,"journal":{"name":"Nusantara Bioscience","volume":null,"pages":null},"PeriodicalIF":0.4,"publicationDate":"2020-10-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44196067","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 3
Human myiasis survey in Ilam Province, Southwest of Iran 伊朗西南部伊拉姆省的人类蝇蛆病调查
IF 0.4
Nusantara Bioscience Pub Date : 2020-10-20 DOI: 10.13057/nusbiosci/n120209
M. Akbari, J. Rafinejad, A. Hanafi-Bojd, A. Aivazi, A. Biglarian, Soraya Sheikhi, Zahra Shavali, K. Akbarzadeh
{"title":"Human myiasis survey in Ilam Province, Southwest of Iran","authors":"M. Akbari, J. Rafinejad, A. Hanafi-Bojd, A. Aivazi, A. Biglarian, Soraya Sheikhi, Zahra Shavali, K. Akbarzadeh","doi":"10.13057/nusbiosci/n120209","DOIUrl":"https://doi.org/10.13057/nusbiosci/n120209","url":null,"abstract":"Akbari M, Rafinejad J, Hanafi-Bojd AA, Aivazi AA, Biglarian A, Sheikhi S, Shavali Z, Akbarzadeh K. 2020. Human myiasis survey in Ilam Province, Southwest of Iran. Nusantara Bioscience 12: 143-147. Myiasis is the infestation of live human and vertebrate animals with dipterous larvae, which at least for a period. Ilam Province of Iran is one of the most important animal husbandry areas, especially nomadic, in Iran. The objective of this study was to identify the prevalence of myiasis in shepherds in Ilam Province. A crosssectional study was conducted among the shepherds in Ilam Province, western Iran. Out of the 11 counties in Ilam Province, 6 were randomly chosen from three different climates for this study. A questionnaire was used by a trained interviewer to obtain the information from subjects. The disease has been seen in spring, summer, and autumn seasons. About 94.1% of people have been infested at least once. Pharyngeal myiasis had the highest prevalence with 58.3%. Itchy, painful throat, sneeze, cough, and headache were common symptoms. About 85.1% of people described the symptoms of the disease as severe and very severe. About 75.4% stated that the duration of the disease was more than 5 days. According to the results of the study, it was found that the prevalence of myiasis among shepherds in the Ilam Province is high and it is necessary to take appropriate measures to control the disease and increase health literacy.","PeriodicalId":19481,"journal":{"name":"Nusantara Bioscience","volume":null,"pages":null},"PeriodicalIF":0.4,"publicationDate":"2020-10-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46797732","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Growth and yield response of shallot (Allium ascalonicum L. var. Tuktuk) from different source materials applied with liquid biofertilizers 液体生物肥料对不同原料葱生长及产量的影响
IF 0.4
Nusantara Bioscience Pub Date : 2020-09-25 DOI: 10.13057/NUSBIOSCI/N120207
J. H. Purba, P. Wahyuni, Z. Zulkarnaen, N. Sasmita, I. G. A. D. Yuniti, Ni Putu Pandawani
{"title":"Growth and yield response of shallot (Allium ascalonicum L. var. Tuktuk) from different source materials applied with liquid biofertilizers","authors":"J. H. Purba, P. Wahyuni, Z. Zulkarnaen, N. Sasmita, I. G. A. D. Yuniti, Ni Putu Pandawani","doi":"10.13057/NUSBIOSCI/N120207","DOIUrl":"https://doi.org/10.13057/NUSBIOSCI/N120207","url":null,"abstract":"Purba JH, Wahyuni PS, Zulkarnaen, Sasmita N, Yuniti IGD, Pandawani NP. 2020. Growth and yield response of shallot (Allium ascalonicum L. var. Tuktuk) from different source materials applied with liquid biofertilizers. Biodiversitas 21: 127-133. This research was to examine growth and yield of shallots using different sources of propagation material, namely true shallot seed (TSS) and bulbs. Soil biological fertility, which was generally low, was improved by the addition of liquid organic fertilizer. The purpose of this study a) to determine the differences in the propagation of plants from seeds and bulbs of shallot Tuktuk varieties, and b) to determine the effect of liquid biofertilizer maxigrow and rhizobacteria. The study used a one-factor randomized design. The results showed that the growth and yield of shallots propagated with bulbs were better than the origin of the seeds. The treatment of the two types of liquid biofertilizer produces tangible growth and yield, but there was no significant difference between the two kinds of liquid organic fertilizer.","PeriodicalId":19481,"journal":{"name":"Nusantara Bioscience","volume":null,"pages":null},"PeriodicalIF":0.4,"publicationDate":"2020-09-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45970525","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 12
The use of betel (Piper betle) leaves for maintaining the health of women and children at various ethnic groups in Indonesia 印尼各民族使用槟榔叶来维护妇女和儿童的健康
IF 0.4
Nusantara Bioscience Pub Date : 2020-09-21 DOI: 10.13057/NUSBIOSCI/N120206
L. Widowati, Lestari Handayani, R. Mujahid
{"title":"The use of betel (Piper betle) leaves for maintaining the health of women and children at various ethnic groups in Indonesia","authors":"L. Widowati, Lestari Handayani, R. Mujahid","doi":"10.13057/NUSBIOSCI/N120206","DOIUrl":"https://doi.org/10.13057/NUSBIOSCI/N120206","url":null,"abstract":"Widowati L, Handayani L, Mujahid R. 2020. The use of betel (Piper betle) leaves for maintaining the health of women and children at various ethnic groups in Indonesia. Nusantara Bioscience 12: 120-126. Betel is considered as one of the popular medicinal plants. Traditional uses of betel are mainly for maternal and child health, and frequently applied by the local communities. The study was carried out to determine the traditional use of betel. The method used a descriptive approach by analyzing the data collected from the RISTOJA Project in the year of 2012, 2015, and 2017. Data collection was conducted in 34 provinces of Indonesia through the survey of local knowledge of ethnomedicine and community-based medicinal plants. We collected the data using semi-structured interviews with traditional healers. The study revealed some medicinal related purposes, such as (i) Beauty care/cosmetic; (ii) Female genital organ; (iii) Fertility disorders; (iv) Pre and postnatal; (v) Stimulating breast milk, and (vi) Baby and children care. The RISTOJA project proved that the use of betel in health care for women and children is a lot so that it should be more developed. Previous studies also proved that betel is efficacious and safe for women and children. On the contrary, unhygienic way of services in traditional rituals and beliefs need to be supervised so that there is no harmful effect on the consumer. We propose establishing guidance to the traditional healers so that they can understand the safety and efficacy of traditional medicine and hygienic traditional health services.","PeriodicalId":19481,"journal":{"name":"Nusantara Bioscience","volume":null,"pages":null},"PeriodicalIF":0.4,"publicationDate":"2020-09-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45359588","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 4
The application of NPK fertilizer boosts the nutrient uptake status and biomass production of Vernonia amygdalina 施用NPK肥料可提高扁桃对养分的吸收和生物量的生产
IF 0.4
Nusantara Bioscience Pub Date : 2020-09-09 DOI: 10.13057/nusbiosci/n120205
D. Susanto, R. Amirta
{"title":"The application of NPK fertilizer boosts the nutrient uptake status and biomass production of Vernonia amygdalina","authors":"D. Susanto, R. Amirta","doi":"10.13057/nusbiosci/n120205","DOIUrl":"https://doi.org/10.13057/nusbiosci/n120205","url":null,"abstract":"Susanto D, Amirta R. 2020. The application of NPK fertilizer boosts the nutrient uptake status and biomass production of Vernonia amygdalina. Nusantara Bioscience 12: 114-119. Vernonia amygdalina Delile is a medicinal plant introduced in Indonesia. This study aims to determine the nutrients absorption status and growth of V. amygdalina plants planted with a spacing of 1x1 m. The study used a complete randomized block design with NPK compound fertilizer treatment with five doses of fertilizer namely 0 g (without fertilizer) as a control, 40 g, 80 g, 120 g, and 140 g, three blocks each group consisted of 10 plants so that in total there were 150 plants. The results showed that NPK fertilizer increased growth and the biomass of V. amygdalina. The best growth of V. amygdalina plant was achieved in plants applied with 160g per plant NPK fertilizer in which the average of stem diameter and plant height were 6.69 ± 0.930 cm and 611.67 ± 12.71 cm, while the estimated biomass yield was 407 tons.ha-1. The most nutritional elements accumulated in plant biomass was the calcium (1279.49 kg.ha), followed by magnesium (1167.0642 kg.ha), phosphorus (536.64 kg.ha), potassium (419.71 kg.ha) and nitrogen (134.4 kg.ha). We propose that these base nutrients are highly necessary for the cultivation of V. amygdalina as biomass feedstock or medicine plant.","PeriodicalId":19481,"journal":{"name":"Nusantara Bioscience","volume":null,"pages":null},"PeriodicalIF":0.4,"publicationDate":"2020-09-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44530271","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
Short Communication: Stimulatory effect of Curcuma mangga on immune response against Staphylococcus aureus 简短交流:姜黄对金黄色葡萄球菌免疫反应的刺激作用
IF 0.4
Nusantara Bioscience Pub Date : 2020-09-07 DOI: 10.13057/nusbiosci/n120204
Yuandani Yuandani, S. E. Nugraha, L. Laila, S. Silaban, F. Ramadhani
{"title":"Short Communication: Stimulatory effect of Curcuma mangga on immune response against Staphylococcus aureus","authors":"Yuandani Yuandani, S. E. Nugraha, L. Laila, S. Silaban, F. Ramadhani","doi":"10.13057/nusbiosci/n120204","DOIUrl":"https://doi.org/10.13057/nusbiosci/n120204","url":null,"abstract":"Yuandani, Nugraha SE, Laila L, Silaban SD, Ramadhani F. 2020. Short Communication: Stimulatory effect of Curcuma mangga on immune response against Staphylococcus aureus. Nusantara Bioscience 12: 109-113. Recently, the ethanol extract of Curcuma mangga Val. rhizomes were found to have immunomodulatory activity by enhancing phagocytic ability. This study was carried out to evaluate the effect of C. mangga rhizomes on antibody titer and delayed-type hypersensitivity response in normal and doxorubicin-induced rats against Staphylococcus aureus. The extract was administered orally at doses of 100, 200, and 400 mg/kg body weight (bw) to rats for 72 hours prior to sensitization of Staphylococcus aureus, then continued for 14 days. Doxorubicin (4.67 mg/kg bw) was administered on days 8 and 11 to suppress the immune system. The antibody titer of normal and immune-suppressed rats after the treatment with C. mangga ethanolic extract was significantly higher than the rats with negative control (P<0.05). Ethanol extract of C. mangga also demonstrated stimulation on delayed-type hypersensitivity response which was indicated by the increase of paw volume. The extract at dose of 400 mg/kg bw showed higher immunostimulatory activity than Levamisole as a positive control. The results indicated that the ethanol extract of C. mangga shows immunostimulatory activity, confirming its potential to be developed as a therapeutic agent.","PeriodicalId":19481,"journal":{"name":"Nusantara Bioscience","volume":null,"pages":null},"PeriodicalIF":0.4,"publicationDate":"2020-09-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42197784","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
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