Nephro-urology Monthly最新文献_第10页

The Effect of Oxalobacter formigenes Colonization in Patients with Calcium Oxalate Renal Stones in Comparison with Healthy People in Qom: A Case-Control Study 库姆地区草酸钙肾结石患者与健康人群中formigenes草酸杆菌定植的影响:一项病例对照研究

Nephro-urology Monthly Pub Date : 2021-08-17 DOI: 10.5812/numonthly.115769

G. Jafari, Reza Fotouhi Ardakani, J. Nowroozi, M. S. Soltanpour, M. Akhavan Sepahi

{"title":"The Effect of Oxalobacter formigenes Colonization in Patients with Calcium Oxalate Renal Stones in Comparison with Healthy People in Qom: A Case-Control Study","authors":"G. Jafari, Reza Fotouhi Ardakani, J. Nowroozi, M. S. Soltanpour, M. Akhavan Sepahi","doi":"10.5812/numonthly.115769","DOIUrl":"https://doi.org/10.5812/numonthly.115769","url":null,"abstract":"Background: Urinary stones are a major problem world, and their incidence has increased significantly in recent years. Objectives: This study aimed to develop a simple and rapid molecular method based on PCR and qPCR assays to detect Oxalobacter formigenes (which causes oxalate degradation in intestines) in fecal samples of healthy volunteers and patients with calcium oxalate nephrolithiasis, and determine the amount of urinary oxalate in the two groups. Methods: This study was performed on urine and fecal samples of 73 patients with kidney stones and 52 healthy individuals. After DNA extraction, PCR and qPCR assays were performed on two gene regions of Oxalobacter formigenes, OXC, and FRC. Also, urine oxalate was measured in the study population using biochemical methods. Results: We found that the presence of Oxalobacter formigenes could reduce the risk of kidney stones and calcium oxalate stones. In fact, both FRC and OXC genes were involved in the diagnosis of Oxalobacter formigenes; however, the results based on the FRC gene showed higher efficiency. In addition, the presence or absence of stones did not affect the amount of urinary excretion of oxalate, rather it is affected by diet. Conclusions: Molecular identification of Oxalobacter formigenes by PCR and qPCR assays allows rapid, specific, and reproducible detection in fecal samples, which also allows immediate processing of these samples in clinical conditions.","PeriodicalId":19466,"journal":{"name":"Nephro-urology Monthly","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-08-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43024816","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Plasma D-Dimer as a Marker of Urinary Tract Infection in Children 血浆d -二聚体作为儿童尿路感染的标志物

Nephro-urology Monthly Pub Date : 2021-08-17 DOI: 10.5812/numonthly.117054

Maryam Esteghamati, K. Ghasemi, Z. Javaheri, Ghazal Zoghi

{"title":"Plasma D-Dimer as a Marker of Urinary Tract Infection in Children","authors":"Maryam Esteghamati, K. Ghasemi, Z. Javaheri, Ghazal Zoghi","doi":"10.5812/numonthly.117054","DOIUrl":"https://doi.org/10.5812/numonthly.117054","url":null,"abstract":"Background: Urinary tract infections (UTIs) are very common in children. Several biomarkers have been used for the diagnosis of UTI and prediction of renal parenchymal involvement. Objectives: This study aimed to evaluate plasma D-dimer as a diagnostic marker of UTI in children. Methods: This cross-sectional study included 41 children aged 1 month to 14 years with their first febrile UTI confirmed by positive urine culture referred to Bandar Abbas Children’s Hospital, Iran, from October 1, 2017, to April 1, 2018. Participants’ demographic features, including age and gender were recorded. White blood cell (WBC) count, percentage of neutrophils, erythrocyte sedimentation rate (ESR), C-reactive protein (CRP), and serum D-dimer were measured in random blood samples for all the patients. Results: Out of 41 children (mean age: 5.50 ± 4.01 years) evaluated in this study, 6 (14.6%) were male, and 35 (85.4%) were female. The mean plasma D-dimer level was 1496.49 ± 2787.55 µg/L. A significant positive correlation was found between D-dimer with ESR (r = 0.647, P = 0.026) and CRP (r = 0.525, P = 0.001). Plasma D-dimer was not associated with age; however, age was inversely correlated with WBC count (r = -0.327, P = 0.037). No significant relationship was found between plasma D-dimer, ESR, CRP, WBC count, and neutrophil percentage with gender (P > 0.05). Conclusions: According to our results, in children aged 1 month to 14 years with culture-confirmed UTI, plasma D-dimer is positively correlated with ESR and CRP. Nevertheless, D-dimer appears not to be influenced by age or gender. Further studies are required to confirm the utility of D-dimer as a diagnostic marker of UTI in children.","PeriodicalId":19466,"journal":{"name":"Nephro-urology Monthly","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-08-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41681095","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Prevalence of Hypertension and Prehypertension in Iranian Children 伊朗儿童高血压和高血压前期患病率

Nephro-urology Monthly Pub Date : 2021-08-16 DOI: 10.5812/numonthly.114828

Farshid Kompani, A. Nickavar

{"title":"Prevalence of Hypertension and Prehypertension in Iranian Children","authors":"Farshid Kompani, A. Nickavar","doi":"10.5812/numonthly.114828","DOIUrl":"https://doi.org/10.5812/numonthly.114828","url":null,"abstract":"Background: Hypertension (HTN) is a significant public health problem worldwide. Early diagnosis of HTN and its related risk factors has been considered as one of the main requirements of general healthcare in children. Objectives: This study aimed to examine the nomograms of normal systolic and diastolic blood pressure (BP) and the prevalence of asymptomatic HTN and pre-HTN in a population of school-aged children. Methods: Systolic and diastolic BP, height, and weight were measured in 5811 healthy school-aged children (2904 males and 2907 females) during healthcare visits. HTN was defined as systolic or diastolic BP ≥ 95th percentile for age, gender, and height of the screened population on ≥ 3 occasions. Pre-HTN was considered as systolic or diastolic BP between 90 - 95 percentile. Results: HTN and pre-HTN were detected in 8.4% and 7.8% of the children, respectively. The prevalence of HTN was 8.6% among the males and 8.2% among the females. Systolic HTN and pre-HTN were detected in 5.8 and 6.4% of the cases compared to diastolic HTN and pre-HTN observed in 5.9 and 6.1% of the participants, respectively. In addition, HTN was detected in 27.9% of children with obesity. Conclusions: According to the high incidence of asymptomatic HTN and pre-HTN in asymptomatic children, it is recommended to perform routine BP measurement during medical care visits of all healthy school children and to prevent and treat obesity in childhood.","PeriodicalId":19466,"journal":{"name":"Nephro-urology Monthly","volume":"144 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-08-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41300348","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Evaluation of the Relationship Between Body Mass Index (BMI) and DNA Fragmentation Index Changes in Primary Infertile Patients Following Microscopic Sub Inguinal Varicocelectomy 原发性不孕症患者显微腹股沟下精索静脉曲张切除术后体重指数(BMI)与DNA片段化指数变化关系的评价

Nephro-urology Monthly Pub Date : 2021-08-11 DOI: 10.5812/numonthly.115829

M. dadfar, A. Kheradmand, H. Mombeini, J. Asl, Abbas Mahdavian

{"title":"Evaluation of the Relationship Between Body Mass Index (BMI) and DNA Fragmentation Index Changes in Primary Infertile Patients Following Microscopic Sub Inguinal Varicocelectomy","authors":"M. dadfar, A. Kheradmand, H. Mombeini, J. Asl, Abbas Mahdavian","doi":"10.5812/numonthly.115829","DOIUrl":"https://doi.org/10.5812/numonthly.115829","url":null,"abstract":"Objectives: To investigate changes in DNA fragmentation index in primary infertile patients with varicocele, which is followed by microscopic subingual varicocelectomy in different groups based on body mass index (BMI). Methods: This study was performed in 100 patients with primary infertility with varicocele. Patients were divided into three groups (normal (N), overweight (OW), and obese (OB)) based on BMI index. DNA fragmentation index (DFI) parameters were evaluated before and 6 months after varicocelectomy. For DFI analysis, the SCD (sperm chromatin dispersion test) method was used. Data were analyzed using t-test, Chi-square, and ANOVA. Results: In this study, the mean age of participants was 33.6 and their mean BMI was 28.6, that 51 patients underwent bilateral varicocelectomy and 49 patients underwent left varicocelectomy surgery. In this study, a comparison of DFI before and 6 months after surgery showed a decrease in DFI in all three groups. The difference was 23 in the normal weight group, 11.2 in the overweight group and 9.58 in the obese group, which is statistically significant (PV < 0.05). Also, in comparison with the rate of DFI reduction between groups, the normal weight group showed a greater decrease than the overweight and obese group. This difference was statistically significant (PV < 0.05), while comparing the rate of DFI reduction between the two groups of overweight and obese, was observed no significant difference (PV = 0.635). Conclusions: Although DFI level decreased significantly 6 months after surgery in all groups with different body mass index. However, the rate of reduction was not the same in different groups and was higher in normal-weight patients than in overweight and obese individuals. But there was no significant difference in the rate of reduction between the overweight and obese groups.","PeriodicalId":19466,"journal":{"name":"Nephro-urology Monthly","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-08-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42567542","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Case Report: A Pediatric COVID-19 Patient with Pyelonephritis and Febrile Seizure as a Rare Clinical Manifestations 1例小儿新冠肺炎合并肾盂肾炎伴发热性惊厥少见临床表现

Nephro-urology Monthly Pub Date : 2021-08-07 DOI: 10.5812/numonthly.116376

M. Rezagholizamenjany, P. Yousefichaijan, Fakhreddin Shariatmadari, M. Kahbazi, Vahid Falahati, Y. Gandi, J. Nazari

引用次数: 0

Henoch-Schoenlein Purpura Following Severe Acute Respiratory Syndrome Coronavirus-2 Infection: A Case Report 冠状病毒2型感染致过敏性紫癜1例

Nephro-urology Monthly Pub Date : 2021-08-03 DOI: 10.5812/numonthly.116227

Saeed Soleiman-Meigooni, Ramin Yaghmayee, Ramin Hamidi-Farahani, Mehdi Ahmadi, Allahyar Taheri, A. Asgari, Azam Soleimani Najafabadi

{"title":"Henoch-Schoenlein Purpura Following Severe Acute Respiratory Syndrome Coronavirus-2 Infection: A Case Report","authors":"Saeed Soleiman-Meigooni, Ramin Yaghmayee, Ramin Hamidi-Farahani, Mehdi Ahmadi, Allahyar Taheri, A. Asgari, Azam Soleimani Najafabadi","doi":"10.5812/numonthly.116227","DOIUrl":"https://doi.org/10.5812/numonthly.116227","url":null,"abstract":"Introduction: As the novel coronavirus pandemic continues to affect people worldwide, immune-mediated inflammatory syndromes related to this virus have been reported. SARS Coronavirus-2 infection disease (COVID-19) may accompany various cutaneous symptoms, such as viral exanthems or wheels. These symptoms may occur at the early course of the disease or after that. Cutaneous symptoms of COVID-19 usually have a favorable outcome. Case Presentation: We presented a rare case of inpatient COVID-19 pneumonia, who developed a purpuric rash, abdominal pain, and hematuria. His dermal histopathological study revealed small-vessel vasculitis. We diagnosed Henoch–Schoenlein purpura based on clinical and histopathological findings and treated him with intravenous dexamethasone followed by oral prednisolone. The purpuric rashes disappeared in two weeks. Conclusions: Cutaneous manifestation of COVID-19 is usually diffuse maculopapular rashes. Other presentations include vesicular rashes and acral cyanosis. Dermal histopathological study in most patients with COVID-19 who developed cutaneous symptoms revealed perivascular inflammation and microthrombus in some cases. Thus, COVID-19 should be considered in any patient with a new onset of cutaneous symptoms.","PeriodicalId":19466,"journal":{"name":"Nephro-urology Monthly","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-08-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46766845","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The Relationship Between Nutritional Status Based on Subjective Global Assessment and Dialysis Adequacy 基于主观整体评估的营养状况与透析充分性的关系

Nephro-urology Monthly Pub Date : 2021-08-02 DOI: 10.5812/numonthly.116254

E. Afaghi, A. Tayebi, Seyedeh Azam Sajadi, A. Ebadi

{"title":"The Relationship Between Nutritional Status Based on Subjective Global Assessment and Dialysis Adequacy","authors":"E. Afaghi, A. Tayebi, Seyedeh Azam Sajadi, A. Ebadi","doi":"10.5812/numonthly.116254","DOIUrl":"https://doi.org/10.5812/numonthly.116254","url":null,"abstract":"Background: Malnutrition is common in patients undergoing hemodialysis and leads to a decrease in dialysis adequacy. The evaluation of dialysis adequacy is very important. Objectives: This study was done to investigate the relationship between patients’ nutrition status based on Subjective Global Assessment (SGA) and their dialysis adequacy. Methods: This cross-sectional descriptive study was conducted in Tehran, Iran, in 2019. Three hundred qualified patients were selected by cluster sampling. Before the dialysis session, measurement of height and weight and blood sampling for albumin, total iron-binding capacity (TIBC), blood urea nitrogen (BUN), and creatinine (Cr) assessment were performed. After the dialysis session, measurement of weight and second sampling for BUN were done. SGA forms were filled by patients. Patients’ dialysis adequacy was calculated based on the DaugirdasII formula, and data were analyzed using SPSS 21. Results: From 300 patients, 128 cases (42.7%) had normal nutrition status, while 148 cases (49.3%) had mild to moderate malnutrition and 24 cases (8%) had severe malnutrition with mean dialysis adequacy of 1.07. The present study showed a significant statistical relationship between malnutrition and education (P < 0.001), body mass index (BMI) (P = 0.03), albumin (P < 0.001), TIBC (P < 0.001), and dialysis adequacy (P < 0.001). Gender, age, and dialysis duration showed no significant relationship with nutrition status based on the SGA index. Conclusions: The findings showed a high relative frequency of malnutrition and a decrease in patients’ dialysis adequacy, which emphasize the patient’s educational level, proper management of nutrition along with regular consultations by nutritionists, better implementation of the dialysis procedure, and regular follow-up of dialysis adequacy.","PeriodicalId":19466,"journal":{"name":"Nephro-urology Monthly","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-08-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44394182","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

Effect of N-Acetylcysteine on hsCRP in Patients on Continues Ambulatory Peritoneal Dialysis: A Quasi-Experimental Study n -乙酰半胱氨酸对持续腹膜透析患者hsCRP的影响:一项准实验研究

Nephro-urology Monthly Pub Date : 2021-07-28 DOI: 10.5812/numonthly.113990

F. Najafi, Razieh Sadat Mousavi-roknabadi, A. Pirdehghan, M. Rahimian, Nader Nourimajalan

{"title":"Effect of N-Acetylcysteine on hsCRP in Patients on Continues Ambulatory Peritoneal Dialysis: A Quasi-Experimental Study","authors":"F. Najafi, Razieh Sadat Mousavi-roknabadi, A. Pirdehghan, M. Rahimian, Nader Nourimajalan","doi":"10.5812/numonthly.113990","DOIUrl":"https://doi.org/10.5812/numonthly.113990","url":null,"abstract":"Background: Inflammatory processes are proved in patients with chronic kidney disease (CKD) as one of the leading causes of mortality and morbidity. N-acetylcysteine (NAC) is known as an antioxidant drug with anti-inflammatory effects. Objectives: This study aimed to evaluate the effects of NAC on hsCRP in CKD patients on peritoneal dialysis. Methods: This quasi-experimental self-controlled study examined adult CKD patients on peritoneal dialysis referred to the peritoneal dialysis clinic. The participants were assigned into two groups (A: CRP of 5 - 15 mg/L and B: CRP < 5 mg/L), and both groups were treated with oral NAC 600mg twice a day for eight weeks. First, the hsCRP was measured before and after the intervention, and then all the collected data were analyzed. Results: Forty patients (n = 24 in the group A and n = 26 in the group B) participated in this study. NAC decreased the hsCRP level in both groups (P = 0.001 in the group A vs. P = 0.002 in group B); however, the decrease was more prominent in the group A (P = 0.013). The hsCRP decrease was more significant in women (P = 0.002) in general and women in the group B (P = 0.02) in particular. The hsCRP variation had a significant relationship with the underlying disease (P = 0.009). There was no significant correlation between the hsCRP variation with age (r = -0.173, P = 0.285) and the duration of dialysis. Conclusions: The administration of NAC (600 mg, twice a day for eight weeks) significantly decreased the level of hsCRP in patients on peritoneal dialysis, especially in those with CRP = 5 - 15 mh/L. The decrease has no relationship with age and duration of dialysis; however, it was more highlighted in women.","PeriodicalId":19466,"journal":{"name":"Nephro-urology Monthly","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-07-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46732870","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

A Rare Case of Vasculitis ANCA of Bladder and Urethra Providing to Vesicovaginal Fistula and Early Recurrence of Illness 膀胱尿道血管炎ANCA致膀胱阴道瘘及早期复发1例

Nephro-urology Monthly Pub Date : 2021-07-28 DOI: 10.5812/numonthly.114971

T. Gawlik-Jakubczak

{"title":"A Rare Case of Vasculitis ANCA of Bladder and Urethra Providing to Vesicovaginal Fistula and Early Recurrence of Illness","authors":"T. Gawlik-Jakubczak","doi":"10.5812/numonthly.114971","DOIUrl":"https://doi.org/10.5812/numonthly.114971","url":null,"abstract":"Introduction: Vasculitis of the bladder and urethra is a rare disease. Its presentation, as a pelvis tumor, indicates the cancerous nature of the lesion. An incorrect diagnosis can result in the removal of the bladder. Case Presentation: We described a 56-year-old woman (born in 1964) with a vesicovaginal fistula, which arose from vasculitis ANCA. Establishing the correct diagnosis was a long and complicated process. During diagnosis, a urogenital fistula was created due to the deepening of inflammatory necrotic lesions. Remission was achieved by pharmacological treatment. As a result, fistula surgical treatment became possible. An unexpected relapse of vasculitis was diagnosed based on the bladder emptying symptoms. Repeating the treatment resulted in a complete response. Eventually, we obtained a cure of regional vasculitis while maintaining the bladder and urethra, which translated into an increased quality of life for the patient. Conclusions: Correct diagnosis before surgery is of crucial importance. Combined pharmacology and surgery prevents removal of the bladder. Careful observation of symptoms allowed for the early detection of recurrent vasculitis.","PeriodicalId":19466,"journal":{"name":"Nephro-urology Monthly","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-07-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48613679","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Intrathoracic Renal Ectopia: A Case Report and Review of the Literature 胸腔内肾脏异位1例报告并文献复习

Nephro-urology Monthly Pub Date : 2021-07-28 DOI: 10.5812/numonthly.114552

M. Khalili, M. Rouzrokh, Mohammad Sadegh Ghadiri, Roya Ansari, Saeed Alerasol

引用次数: 0