EJIFCC Pub Date : 2020-09-29 eCollection Date: 2020-09-01

Ellie Dow, Tim James

引用次数: 0

Diagnostic Challenges with Acyclovir Crystalluria - A Case Study. 阿昔洛韦结晶尿症的诊断挑战-一个案例研究。

EJIFCC Pub Date : 2020-06-02 eCollection Date: 2020-06-01

Alicia R Andrews, Darryl Yu, Andrew W Lyon

{"title":"Diagnostic Challenges with Acyclovir Crystalluria - A Case Study.","authors":"Alicia R Andrews, Darryl Yu, Andrew W Lyon","doi":"","DOIUrl":"","url":null,"abstract":"Background/objective: Marked to abundant crystalluria may cause significant morbidity due to acute renal injury. Intravenous acyclovir administration may result in a pathologic crystalluria, especially in cases with increased renal concentration of the drug. It is important that clinical laboratory staff recognize and communicate the presence of abundant crystalluria to clinical staff to avoid irreversible kidney injury.Methods: We report a case of crystalluria in a patient treated empirically with intravenous acyclovir for possible viral meningitis.Results: Opaque \"milky\" urine was submitted for urine analysis which showed abundant long needle-shaped brightly birefringent crystals under polarized light microscopy and was diagnosed as acyclovir crystalluria.Conclusions: Any case of moderate to abundant crystalluria should be reported in a timely manner to the clinical staff to facilitate treatment modification to reduce the risk of acute kidney injury. Laboratory staff should be aware and recognize acyclovir treatment as a possible cause of pathologic crystalluria.","PeriodicalId":193105,"journal":{"name":"EJIFCC","volume":"31 2","pages":"157-163"},"PeriodicalIF":0.0,"publicationDate":"2020-06-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/8c/39/ejifcc-31-157.PMC7294811.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38058958","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Artificial Intelligence-Powered Search Tools and Resources in the Fight Against COVID-19. 抗击COVID-19的人工智能搜索工具和资源。

EJIFCC Pub Date : 2020-06-02 eCollection Date: 2020-06-01

Larry J Kricka, Sergei Polevikov, Jason Y Park, Paolo Fortina, Sergio Bernardini, Daniel Satchkov, Valentin Kolesov, Maxim Grishkov

引用次数: 0

Blood Lead Levels in Rag-Pickers of Kathmandu and its Association with Hematological and Biochemical Parameters. 加德满都拾荒者血铅水平及其与血液和生化参数的关系。

EJIFCC Pub Date : 2020-06-02 eCollection Date: 2020-06-01

Keyoor Gautam, Vivek Pant, Santosh Pradhan, Devish Pyakurel, Bijay Bhandari, Abha Shrestha

{"title":"Blood Lead Levels in Rag-Pickers of Kathmandu and its Association with Hematological and Biochemical Parameters.","authors":"Keyoor Gautam, Vivek Pant, Santosh Pradhan, Devish Pyakurel, Bijay Bhandari, Abha Shrestha","doi":"","DOIUrl":"","url":null,"abstract":"Introduction: Lead poisoning is a common health problem in Nepal and there are a limited number of studies on blood lead levels in various population groups. Rag-pickers are those people who visit from house to house to collect the materials that can be recycled and thus earn their livelihood. The present study was designed to evaluate blood lead level (BLL) and its relationship between hematological and biochemical parameters in rag-pickers working in Kathmandu.Methods: An observational cross-sectional study among 50 ragpickers working in the selected area of Kathmandu was done in May 2019 after obtaining ethical approval from the Nepal health research council. Capillary and venous blood was drawn from each participant after written consent to measure the BLL, aspartate aminotransferase, alanine aminotransferase, total bilirubin, creatinine, glucose and to test for a complete blood count. Whole blood was also screened for the presence of hemoglobin variants in cases with abnormal red blood cell indices. Data was analyzed using SPSS (Version 20.0).Result: All rag pickers were men with mean age of 32.56 ± 12.51 years. The mean BLL among ragpickers was 11.6 ± 7.23 μg/dL. High eosinophil count was found (8.27 ± 5.49 %) in 27 cases (54%) having no significant association with BLL. The mean BLL was higher (12.89 μg/dL) in a cohort of workers who pick and recycle electronic waste. Beta-Thalassemia trait was seen in four cases, all of them had high BLL. No significant association of BLL with the number of years worked by rag picker was found. Similarly, no significant association of BLL with hematological and biochemical parameters was found.Conclusion: Rag-pickers working in Kathmandu are at increased risk of lead toxicity. The use of protective gloves, masks, shoes and clothes along with a regular medical examination of this vulnerable group is recommended.","PeriodicalId":193105,"journal":{"name":"EJIFCC","volume":"31 2","pages":"125-133"},"PeriodicalIF":0.0,"publicationDate":"2020-06-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/1c/4e/ejifcc-31-125.PMC7294816.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38059575","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Case Report on Paediatric Nephrotic Syndrome. 小儿肾病综合征1例报告。

EJIFCC Pub Date : 2020-06-02 eCollection Date: 2020-06-01

Shireen Prince, Kunta Naresh, R Tulasi

引用次数: 0

Survey on Stat Tests in Catalan Clinical Laboratories. 加泰罗尼亚临床实验室Stat检测的调查。

EJIFCC Pub Date : 2020-06-02 eCollection Date: 2020-06-01

Ariadna Arbiol-Roca, Dolors Dot-Bach

{"title":"Survey on Stat Tests in Catalan Clinical Laboratories.","authors":"Ariadna Arbiol-Roca, Dolors Dot-Bach","doi":"","DOIUrl":"","url":null,"abstract":"Introduction: The Catalan Association of Clinical Laboratory Sciences (ACCLC) conducted a survey on the vast majority of hospital clinical laboratories in Catalonia. In order to establish a debate on the emergency laboratories and aspects related to the stat tests.Materials and methods: An online survey was distributed by ACCLC to 69 hospital laboratories in Catalonia. A 30-question survey was designed with 9 different issues. The questionnaire examined general information regarding the hospital and laboratory model, stat laboratory workload, laboratory information system, quality control, critical values results, authorization/validation of results, laboratory report and human resources, among others. The results were reported in number of laboratories and in percentage (%).Results: The total survey response rate was 59 %. 68.3 % stat laboratories biochemistry, haematology and microbiology departments were integrated. The majority (60.9%) of the stat tests were integrated in part with laboratory core. All laboratories employed laboratory information system and are using barcode system. In 75.6% of laboratories all requests were made electronically. 43.9% of laboratories did not give results in international system, only in conventional units. All laboratories participated in internal and external quality assessment programs. Internal quality controls are processed more than once a day in 80.5% of laboratories. The vast majority of laboratories reported critical results (97.6%). 75% of laboratories have a medical specialist (biochemistry or analysis). The average number of laboratory technicians was 4.Conclusions: Our study highlighted the variation in how emergency laboratories and stat test are run across Catalonia.","PeriodicalId":193105,"journal":{"name":"EJIFCC","volume":"31 2","pages":"134-144"},"PeriodicalIF":0.0,"publicationDate":"2020-06-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/49/5a/ejifcc-31-134.PMC7294814.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38059576","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Reference Value for Serum Zinc Level of Adult Population in Bangladesh. 孟加拉国成人血清锌水平的参考值。

EJIFCC Pub Date : 2020-06-02 eCollection Date: 2020-06-01

Nilima Barman, Marium Salwa, Debabrata Ghosh, Muhammed Waliur Rahman, Md Nasir Uddin, M Atiqul Haque

{"title":"Reference Value for Serum Zinc Level of Adult Population in Bangladesh.","authors":"Nilima Barman, Marium Salwa, Debabrata Ghosh, Muhammed Waliur Rahman, Md Nasir Uddin, M Atiqul Haque","doi":"","DOIUrl":"","url":null,"abstract":"Background: Zinc is an essential trace element that has an enormous role in regulation of physiological processes whose deviant value leads to malfunction in the body. So, establishing a country specific reference value is needed to serve as a standard for the interpretation of laboratory results during clinical decision making.Objective: The objective of this study was to determine the reference value of serum zinc level of adult population in Bangladesh.Materials and methods: The overnight fasting blood was collected from 154 apparently healthy individuals aged 18 to 65 years, from a rural community after considering several criteria. Graphite furnace atomic absorption spectrophotometry (GF-AAS) method was used for serum zinc analysis. The 2.5th and 97.5th percentiles of zinc level were calculated for the reference value according to the recommendations of the International Federation of Clinical Chemistry and Laboratory Medicine (IFCC).Results: The estimated reference range of serum zinc level in sample population was 60-120 μg/dL, where the range was 59-125 μg/dL for male and 50-103 μg/dL for female. Significant differences of serum zinc level between male and female (p<0.001) was observed. However, there was no significant correlation between age of the respondents and serum zinc level (r=0.110, p>0.05).Conclusion: The estimated reference range for serum zinc level in adult population of Bangladesh can serve as a useful indicator for clinical decision making.","PeriodicalId":193105,"journal":{"name":"EJIFCC","volume":"31 2","pages":"117-124"},"PeriodicalIF":0.0,"publicationDate":"2020-06-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/94/b6/ejifcc-31-117.PMC7294812.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38059574","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A Tarnished Toy Story. 《失去光泽的玩具总动员》

EJIFCC Pub Date : 2020-06-02 eCollection Date: 2020-06-01

Michelle K/A Mikhaila Muscat

引用次数: 0

COVID-19: Armageddon before Light? COVID-19:光明前的世界末日?

EJIFCC Pub Date : 2020-06-02 eCollection Date: 2020-06-01

Damien Gruson, Gabriel Ko, David Luu

引用次数: 0

Critical Results Reporting in Portuguese Hospital Laboratories: State-of-the-Art. 关键结果报告在葡萄牙医院实验室:最先进的。

EJIFCC Pub Date : 2020-06-02 eCollection Date: 2020-06-01

Dora Vuljanić, Margarida Pereira, Sérgio Santos, Ana Nikler, Vanja Radišić Biljak, Isabel Cachapuz

{"title":"Critical Results Reporting in Portuguese Hospital Laboratories: State-of-the-Art.","authors":"Dora Vuljanić, Margarida Pereira, Sérgio Santos, Ana Nikler, Vanja Radišić Biljak, Isabel Cachapuz","doi":"","DOIUrl":"","url":null,"abstract":"Introduction: This survey aimed to assess the state-of-the-art of current practices on critical results reporting among Portuguese Clinical Pathology Laboratories. The results of the survey will set basis for future standardization and national guideline development.Materials and methods: The survey was transmitted to 49 Clinical Pathology Laboratories among public hospitals inserted in the Portuguese National Health System. In 27 questions, laboratories were asked about their critical results procedures, critical results list, reporting and further education. Data were analyzed using Microsoft Excel v.2016 and MedCalc Statistical Software version 12.5.0.0 (Ostend, Belgium). Where applicable, the comparison of proportions was used to estimate the level of significance (P<0.05).Results: The response rate was 44/49 (90%), including 36 participants with a defined critical results reporting procedure. Among them, 31 laboratories defined a critical results list, mainly based on published literature (27/31). There was a statistically significant number of laboratories (P=0.019, 24/30) that report different critical results depending on the patient's age, but regardless of disease, ethnicity and location (P>0.05). The majority of laboratories (60%) report critical results via telephone within 15 minutes. Critical results are usually reported by clinical pathologists to physicians. Twenty-five laboratories periodically reevaluate their critical results list.Conclusion: Despite the fact that most of the Portuguese hospitals have a critical results policy, this survey showed high variability among the hospitals concerning critical results reporting practices and critical results list. This survey points out that nationally established procedures and guidelines are urgent step for critical results standardization.","PeriodicalId":193105,"journal":{"name":"EJIFCC","volume":"31 2","pages":"145-156"},"PeriodicalIF":0.0,"publicationDate":"2020-06-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/54/b6/ejifcc-31-145.PMC7294818.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38059577","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

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