Nihon Kokyuki Gakkai zasshi = the journal of the Japanese Respiratory Society最新文献_第8页

Nihon Kokyuki Gakkai zasshi = the journal of the Japanese Respiratory Society Pub Date : 2011-08-01

Megumi Inaba, Sunao Ushijim, Naomi Hirata, Tetsushi Saisyoji, Mitsuhiko Kitaoka, Takeshi Yoshinaga

{"title":"[Methotrexate-related lymphomatoid granulomatosis in a patient with rheumatoid arthritis].","authors":"Megumi Inaba, Sunao Ushijim, Naomi Hirata, Tetsushi Saisyoji, Mitsuhiko Kitaoka, Takeshi Yoshinaga","doi":"","DOIUrl":"","url":null,"abstract":"A 76-year-old man who was taking prednisolone and methotrexate for rheumatoid arthritis presented with gastric ulcers. Chest X-ray images showed multiple pulmonary nodules. Transbronchial lung biopsy specimens showed lymphocytic infiltrates but no malignant cells. The radiographic findings gradually ameliorated over a month, but then deteriorated 5 months later. We performed video-assisted thoracoscopic biopsy of the left lung, and the biopsy specimens showed lymphocytic infiltration with necrosis, in which the atypical lymphocytes were positive for Epstein-Barr virus-encoded small RNAs in situ hybridization (EBER-ISH). A diagnosis of lymphomatoid granulomatosis was determined. One year before this diagnosis, the patient was found to have an inflammatory liver tumor that had disappeared spontaneously within a month. A new pathological review of the liver and stomach lesions demonstrated EBER-ISH-positive lymphocytes, and therefore we assumed that they were pathological features of lymphomatoid granulomatosis. The chest radiographic findings improved gradually after the discontinuation of methotrexate. We therefore suggest that methotrexate treatment may be associated with the development of lymphomatoid granulomatosis in patients with rheumatoid arthritis. Lymphoproliferative disorders, including lymphomatoid granulomatosis, should be considered in patients with rheumatoid arthritis who are receiving methotrexate.","PeriodicalId":19218,"journal":{"name":"Nihon Kokyuki Gakkai zasshi = the journal of the Japanese Respiratory Society","volume":"49 8","pages":"597-601"},"PeriodicalIF":0.0,"publicationDate":"2011-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"30123311","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[A case of pulmonary nocardiosis due to Nocardia cyriacigeorgica with prompt diagnosis by gram stain]. 革兰氏染色快速诊断肺诺卡菌感染cyriacigorgica诺卡菌病1例。

Nihon Kokyuki Gakkai zasshi = the journal of the Japanese Respiratory Society Pub Date : 2011-08-01

Yoshiro Hadano, Norio Ohmagari, Jun Suzuki, Ichiro Kawamura, Keiji Okinaka, Hanako Kurai, Hiroyuki Tomioka, Yusuke Kinugasa, Kiyofumi Ohkusu

引用次数: 0

[A case of pulmonary carcinomatous lymphangitis and multiple pulmonary infarctions from gastric cancer]. [胃癌并发肺癌性淋巴管炎合并多发性肺梗死1例]。

Nihon Kokyuki Gakkai zasshi = the journal of the Japanese Respiratory Society Pub Date : 2011-08-01

Yasuko Koma, Hirofumi Matsuoka, Towa Ryoke, Midori Koyama, Kensuke Fukumitsu, Yoshitaka Kasai, Daiki Masuya, Harukazu Yoshimatsu, Sohei Kitazawa, Yujiro Suzuki

{"title":"[A case of pulmonary carcinomatous lymphangitis and multiple pulmonary infarctions from gastric cancer].","authors":"Yasuko Koma, Hirofumi Matsuoka, Towa Ryoke, Midori Koyama, Kensuke Fukumitsu, Yoshitaka Kasai, Daiki Masuya, Harukazu Yoshimatsu, Sohei Kitazawa, Yujiro Suzuki","doi":"","DOIUrl":"","url":null,"abstract":"We report a case of pulmonary carcinomatous lymphangitis and multiple pulmonary infarctions from gastric cancer. A 58-year-old housewife presented with a complaint of a worsening cough over the previous 6 weeks. Chest radiography and CT scans revealed infiltration and diffuse ground-glass opacities in both lung fields, and she was hospitalized for further examination. No specific findings were found upon screening examination, including bronchoscopy with bronchoalveolar lavage (BAL). However, a CT scan showed mediastinal, hilar and paraaortic lymph node swelling, and therefore we suspected the presence of a malignant tumor. On the 11th hospital day, she suddenly developed severe hypoxia and went into cardiogenic shock. Although there was no sign of a filling defect in the vessels on CT with an intravenous contrast, we diagnosed pulmonary thromboembolism based on other examination findings and began thrombolysis and anticoagulant therapy. Treatment with heparin and urokinase did not improve her condition, and she died on the 14th hospital day. The autopsy findings revealed widespread gastric cancer with pulmonary lymphangitis carcinomatosa and thrombus formation in arterioles throughout the pulmonary lobes: 'Trousseau syndrome'.","PeriodicalId":19218,"journal":{"name":"Nihon Kokyuki Gakkai zasshi = the journal of the Japanese Respiratory Society","volume":"49 8","pages":"577-82"},"PeriodicalIF":0.0,"publicationDate":"2011-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"29977521","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[A case of small-cell lung cancer associated with paraneoplastic limbic encephalitis during chemotherapy]. [化疗期间小细胞肺癌伴副肿瘤边缘脑炎1例]。

Nihon Kokyuki Gakkai zasshi = the journal of the Japanese Respiratory Society Pub Date : 2011-08-01

Kazutoshi Isobe, Riya Nagata, Hiroki Ota, Keishi Sugino, Kazutoshi Shibuya, Sakae Homma

{"title":"[A case of small-cell lung cancer associated with paraneoplastic limbic encephalitis during chemotherapy].","authors":"Kazutoshi Isobe, Riya Nagata, Hiroki Ota, Keishi Sugino, Kazutoshi Shibuya, Sakae Homma","doi":"","DOIUrl":"","url":null,"abstract":"A 75-year-old woman received a diagnosis of small-cell lung cancer (T1N2M0, stage IIIA, limited disease) in January 2009. She received 4 cycles of chemotherapy with etoposide and carboplatin and concurrent radiotherapy (50 Gy/25 Fr) which yielded a complete response. However, recurrence of her small-cell lung cancer occurred in a mediastinal lymph node and the ribs in November 2009. During the 2nd cycle of second-line chemotherapy with nogitecan, she was readmitted to our hospital complaining of amnesia, periods of unconsciousness and convulsions. Her laboratory data on admission revealed normal serum electrolyte and cerebrospinal fluid levels, and electroencephalogram findings. Her neurological symptoms, which mimicked limbic encephalitis improved after steroid pulse therapy plus third-line chemotherapy with amrubicin. The final diagnosis was paraneoplastic limbic encephalitis by positive serum voltage-gated calcium channel antibodies. We hereby report a rare case of small-cell lung cancer associated with paraneoplastic limbic encephalitis during chemotherapy.","PeriodicalId":19218,"journal":{"name":"Nihon Kokyuki Gakkai zasshi = the journal of the Japanese Respiratory Society","volume":"49 8","pages":"602-6"},"PeriodicalIF":0.0,"publicationDate":"2011-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"30123312","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[Allergic bronchopulmonary mycosis due to Schizophyllum commune and Aspergillus fumigatus]. [由裂叶菌和烟曲霉引起的过敏性支气管肺真菌病]。

Nihon Kokyuki Gakkai zasshi = the journal of the Japanese Respiratory Society Pub Date : 2011-08-01

Takashi Ishiguro, Noboru Takayanagi, Akemi Saito, Kazuo Akiyama, Megumi Wakayama, Kazutoshi Shibuya, Yoshihiko Shimizu, Yutaka Sugita, Katsuhiko Kamei

引用次数: 0

[A case of pulmonary varices demonstrated by three-dimensional computed tomography]. 三维计算机断层扫描显示肺静脉曲张1例。

Nihon Kokyuki Gakkai zasshi = the journal of the Japanese Respiratory Society Pub Date : 2011-08-01

Makoto Anzai, Mitsuo Kawamura, Shinichi Matsunaga

引用次数: 0

[Multidisciplinary assessment of effects, safety and procedure of whole lung lavage for 8 patients with autoimmune pulmonary alveolar proteinosis]. [8例自身免疫性肺泡蛋白沉积症全肺灌洗的疗效、安全性和程序的多学科评价]。

Nihon Kokyuki Gakkai zasshi = the journal of the Japanese Respiratory Society Pub Date : 2011-08-01

Chikatoshi Sugimoto, Toru Arai, Akihide Nishiyama, Yasushi Inoue, Tomoko Kagawa, Masanori Akira, Akiko Matsumuro, Masaki Hirose, Masanori Kitaichi, Seiji Hayashi, Yoshikazu Inoue

{"title":"[Multidisciplinary assessment of effects, safety and procedure of whole lung lavage for 8 patients with autoimmune pulmonary alveolar proteinosis].","authors":"Chikatoshi Sugimoto, Toru Arai, Akihide Nishiyama, Yasushi Inoue, Tomoko Kagawa, Masanori Akira, Akiko Matsumuro, Masaki Hirose, Masanori Kitaichi, Seiji Hayashi, Yoshikazu Inoue","doi":"","DOIUrl":"","url":null,"abstract":"We treated 8 cases of autoimmune pulmonary alveolar proteinosis (APAP) with whole lung lavage (WLL) in our hospital and evaluated the disease severity of APAP before and after WLL, adverse events (AEs) and recurrence-free survival in those cases who improved. In all cases, unilateral WLL was performed in both lungs. The median of total lavage volume in unilateral WLL was 17.9 L, and the median procedure time of unilateral WLL was 105 min. Fever was the most frequently observed AE (87.5% of all procedures). Pulmonary function tests (percentage of predicted value of VC, FEV1 and diffusing capacity of carbon monoxide), serum markers (KL-6, surfactant apoprotein (SP)-D, SP-A and carcinoembryonic antigens), arterial blood gas analyses (PaO2, AaDO2) and disease severity score all significantly improved after WLL. The serum levels of anti-granulocyte-macrophage colony-stimulating factor (GM-CSF) antibody temporarily decreased after unilateral WLL, but returned to previous levels (before WLL) in 7 cases. The radiological findings improved in 6 cases. In the 7 improved cases in whom AaDO2 decreased more than 10 Torr, the median recurrence-free survival of APAP after WLL was 17.5 months. We concluded that WLL is an effective and safe method for the treatment of APAP, and all parameters except for anti GM-CSF antibody are useful to evaluate the effect of WLL.","PeriodicalId":19218,"journal":{"name":"Nihon Kokyuki Gakkai zasshi = the journal of the Japanese Respiratory Society","volume":"49 8","pages":"569-76"},"PeriodicalIF":0.0,"publicationDate":"2011-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"29977520","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[A case of pulmonary alveolar proteinosis presenting with miniscule ground-glass opacity in the apex of the left lung]. 肺泡蛋白沉积症1例，表现为左肺顶端微小磨玻璃样混浊。

Nihon Kokyuki Gakkai zasshi = the journal of the Japanese Respiratory Society Pub Date : 2011-07-01

Sayomi Matsushima, Koushi Yokomura, Takashi Matsui, Takafumi Suda, Kingo Chida

引用次数: 0

[Successful treatment of invasive pulmonary aspergillosis with a fungus ball and infiltration by the long-term administration of liposomal amphotericin B]. [长期给予两性霉素B脂质体真菌球浸润治疗侵袭性肺曲霉病的成功研究]。

Nihon Kokyuki Gakkai zasshi = the journal of the Japanese Respiratory Society Pub Date : 2011-07-01

Osamu Hataji, Fumihiko Komada, Hiroyasu Kobayashi, Osamu Taguchi

引用次数: 0

[A case of alveolar hemorrhage caused by gefitinib]. 吉非替尼致肺泡出血1例。

Nihon Kokyuki Gakkai zasshi = the journal of the Japanese Respiratory Society Pub Date : 2011-07-01

Yoritake Sakoda, Yasuhiko Kitasato, Yuko Kawano, Yuichi Mizuta, Shohei Takata, Masayuki Kawasaki

{"title":"[A case of alveolar hemorrhage caused by gefitinib].","authors":"Yoritake Sakoda, Yasuhiko Kitasato, Yuko Kawano, Yuichi Mizuta, Shohei Takata, Masayuki Kawasaki","doi":"","DOIUrl":"","url":null,"abstract":"Although drug-induced interstitial pneumonitis caused by gefitinib is well recognized in Japan, reports of alveolar hemorrhage caused by gefitinib are very rare. We encountered a case of alveolar hemorrhage thought to be caused by gefitinib. A 74-year-old woman with non-small cell lung cancer (adenocarcinoma; cT4NOM0, stage IIIB) had been receiving gefitinib as second-line therapy from January 2009. However, bloody sputum and nasal bleeding were observed 2 weeks after the initiation of gefitinib therapy. Chest radiography and computed tomography revealed ground-glass opacities predominantly in the lower lung fields. Bronchoscopy was performed, and the bronchoalveolar lavage fluid obtained from the right B8 was bloody. Her symptoms and chest ground-glass opacities improved after the withdrawal of gefitinib. Based on these clinical findings, we diagnosed alveolar hemorrhage caused by gefitinib. If chest radiography or computed tomography findings of gefitinib-treated patients show ground-glass opacities, the possibility of not only interstitial pneumonitis, but also alveolar hemorrhage should be considered in the differential diagnosis.","PeriodicalId":19218,"journal":{"name":"Nihon Kokyuki Gakkai zasshi = the journal of the Japanese Respiratory Society","volume":"49 7","pages":"506-10"},"PeriodicalIF":0.0,"publicationDate":"2011-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"29934285","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0