Nihon Kokyuki Gakkai zasshi = the journal of the Japanese Respiratory Society最新文献_第6页

[The origin of frequency dependence of respiratory resistance: airflow simulation study by the use of a 4D pulmonary lobule model]. [呼吸阻力频率依赖性的来源:利用四维肺小叶模型进行气流模拟研究]。

Nihon Kokyuki Gakkai zasshi = the journal of the Japanese Respiratory Society Pub Date : 2011-09-01

Hiroko Kitaoka

{"title":"[The origin of frequency dependence of respiratory resistance: airflow simulation study by the use of a 4D pulmonary lobule model].","authors":"Hiroko Kitaoka","doi":"","DOIUrl":"","url":null,"abstract":"Background and objective: The origin of frequency dependence of respiratory resistance has been explained by ventilation inhomogeneity, however it is unclear which components in the respiratory system generate the frequency dependence. The author constructed a 4D pulmonary lobule model and analyzed relationships between airflow rate, pressure and airway resistance by the use of computational fluid dynamics (CFD).Methods: The lobule model contained bifurcated bronchioles with two adjacent acini in which deformable inter-acinar septa and alveolar duct walls were designed. Constrictive conditions of respective bronchioles were designed, too. 4D finite element models for CFD were generated and airflow simulations were performed under moving boundary conditions of the arbitrary Lagrangean-Eulerean method. From the simulation results, airway resistances for various conditions were calculated.Results: Tissue resistance emerged under the condition of different acinar pressures caused by unequal airway resistances. If the inter-acinar septum was shifted so as to cancel the pressure difference, the acinar pressures were equal in spite of unequal airway resistances, and hence, tissue resistances did not emerge. Therefore, the tissue resistance in the former case is thought to be an index of alveolar pressure inequality (which could be canceled by mechanical interaction of lung parenchyma), rather than a material property of the tissue itself.Conclusions: Inequality of alveolar pressure decreases as the input oscillatory frequency increases. Therefore, frequency dependence of the respiratory resistance should be regarded as a conditional index of the alveolar pressure inequality caused by heterogeneous changes in the intra-pulmonary airway and/or the lung parenchyma.","PeriodicalId":19218,"journal":{"name":"Nihon Kokyuki Gakkai zasshi = the journal of the Japanese Respiratory Society","volume":"49 9","pages":"629-35"},"PeriodicalIF":0.0,"publicationDate":"2011-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"30244267","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[A case of pyogenic spondylitis mimicking spinal invasion of lung cancer]. [化脓性脊柱炎模拟肺癌脊柱侵袭1例]。

Nihon Kokyuki Gakkai zasshi = the journal of the Japanese Respiratory Society Pub Date : 2011-09-01

Yasuki Uchida, Mitsuhiro Tsukino, Eiichi Hayashi, Isao Watanabe, Yuichi Kondo, Kazunari Yamada

{"title":"[A case of pyogenic spondylitis mimicking spinal invasion of lung cancer].","authors":"Yasuki Uchida, Mitsuhiro Tsukino, Eiichi Hayashi, Isao Watanabe, Yuichi Kondo, Kazunari Yamada","doi":"","DOIUrl":"","url":null,"abstract":"A 65-year-old man who had suffered from traumatic spinal cord injury had chronic lumbar pain. He had exacerbation of lumbar pain and intermittent fever and consulted several doctors, but the cause of the lumbar pain was unknown. An orthopedic specialist took an MRI. Spinal MRI showed increased signal intensity at the level of T10-11 and a mass in his right lower lung field, so he was referred to our hospital. Two transbronchial lung biopsy procedures failed to obtain malignant cells. CT guided biopsy showed fibrous and hyalinizing tissue contained plasma cells and lyphocytes. Staphylococcus aureus was cultured from the second bronchial lavage fluids of brush and blood cultures, so we began administration of ampicillin-sulbactam. Avoiding threatened or actual cord compression due to collapse resulting from spinal instability, posterior fusion with instrumentation was done through the back of his chest wall. At once, bone biopsy was done, and showed no malignant cells. As soon as antibacterial treatment was stopped after the operation, he had bloody sputa and fever. The antibacterial agent was resumed and the symptoms improved. The mass decreased in size and lumbar pain improved gradually, so we concluded the diagnosis was pyogenic spondylitis caused by S. aureus. After about 5 months of antibacterial treatment, the tumor substantially diminished.","PeriodicalId":19218,"journal":{"name":"Nihon Kokyuki Gakkai zasshi = the journal of the Japanese Respiratory Society","volume":"49 9","pages":"692-6"},"PeriodicalIF":0.0,"publicationDate":"2011-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"30244151","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[Analysis of predominant bacterial species and clinical backgrounds in lung abscess patients]. 【肺脓肿患者的优势菌种及临床背景分析】。

Nihon Kokyuki Gakkai zasshi = the journal of the Japanese Respiratory Society Pub Date : 2011-09-01

Osamu Nagashima, Shinichi Sasaki, Yukiko Nanba, Yoko Katsura, Hidenori Takekawa, Sachiko Kuriyama, Yasuyo Aso, Yasuko Yoshioka, Takeshi Nakazawa, Sigeru Tominaga

{"title":"[Analysis of predominant bacterial species and clinical backgrounds in lung abscess patients].","authors":"Osamu Nagashima, Shinichi Sasaki, Yukiko Nanba, Yoko Katsura, Hidenori Takekawa, Sachiko Kuriyama, Yasuyo Aso, Yasuko Yoshioka, Takeshi Nakazawa, Sigeru Tominaga","doi":"","DOIUrl":"","url":null,"abstract":"We reviewed the clinicopathological characteristics of lung abscesses retrospectively. We analyzed 89 patients hospitalized from July 1984 to May 2009. Most were men (76/89). There were large proportions with alcohol consumption (29.2%) and dental caries or gingivitis (60.7%). Furthermore, those without other diseases accounted for only 13.5%. Predominant infectious species were clear in 43 cases (48.3%) including identification of bacteria. The identification rate of predominant bacteria improved from 38.5% to 56.0% after initiation of the introduction of expectoration culture, bronchoscopic specimen collection and gingival culture in 2003, facilitating clarification of the predominant bacteria. The Streptococcus anginosus group with predominant bacteria being slightly aerobic streptococci, anaerobic bacterium, and aerobic bacterium was detected in 10, 12, and 31 cases, respectively. The improvement in the identification rate of predominant bacteria was achieved by carrying out examination with close liaison with the staff of our inspection room. In selecting antimicrobials based on diagnostic significance, we should focus on positive identification of predominant bacteria, a factor which appears to have major clinical significance.","PeriodicalId":19218,"journal":{"name":"Nihon Kokyuki Gakkai zasshi = the journal of the Japanese Respiratory Society","volume":"49 9","pages":"623-8"},"PeriodicalIF":0.0,"publicationDate":"2011-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"30244266","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[A case of Churg-Strauss syndrome with subarachnoid hemorrhage and left phrenic nerve paralysis]. [Churg-Strauss综合征伴蛛网膜下腔出血左膈神经麻痹1例]。

Nihon Kokyuki Gakkai zasshi = the journal of the Japanese Respiratory Society Pub Date : 2011-09-01

Kyoko Shimizu, Hiromi Ohoba, Hiroyuki Shimada, Yukihisa Inoue, Yasuto Jinn, Nobuyuki Yoshimura

引用次数: 0

[A case of pulmonary benign metastasizing leiomyoma from the uterus]. 肺良性子宫转移性平滑肌瘤1例。

Nihon Kokyuki Gakkai zasshi = the journal of the Japanese Respiratory Society Pub Date : 2011-09-01

Johsuke Hara, Kouichi Nishi, Yoshio Tsunezuka, Hiroshi Kurumaya, Kazuyoshi Katayanagi, Masaki Fujimura

引用次数: 0

[A case of myocarditis associated with polymyositis preceded by interstitial pneumonia]. [心肌炎合并多发性肌炎并发间质性肺炎1例]。

Nihon Kokyuki Gakkai zasshi = the journal of the Japanese Respiratory Society Pub Date : 2011-09-01

Minako Hamada, Yoshifusa Koreeda, Jiro Nakashioya, Toshifumi Kawabata, Yumiko Tomiyama, Masaharu Kawabata, Hisamichi Aizawa

引用次数: 0

[Pulmonary tumor thrombotic microangiopathy responding to chemotherapy]. [肺肿瘤血栓性微血管病对化疗的反应]。

Nihon Kokyuki Gakkai zasshi = the journal of the Japanese Respiratory Society Pub Date : 2011-09-01

Takashi Ishiguro, Noboru Takayanagi, Masashi Ando, Tsutomu Yanagisawa, Yoshihiko Shimizu, Yutaka Sugita

{"title":"[Pulmonary tumor thrombotic microangiopathy responding to chemotherapy].","authors":"Takashi Ishiguro, Noboru Takayanagi, Masashi Ando, Tsutomu Yanagisawa, Yoshihiko Shimizu, Yutaka Sugita","doi":"","DOIUrl":"","url":null,"abstract":"A 65-year-old man without a history of cancer presented to our hospital because he was suspected of having acute pulmonary thromboembolism. Dyspnea that had developed 1 month before admission, had worsened 1-week before admission. Chest computed tomography showed faint ground-glass opacities in the lung fields without filling defects in the pulmonary arteries. He was transferred to the department of respiratory medicine for further investigation. Perfusion scintigraphy showed multiple, small perfusion defects throughout both lungs, and laboratory data showed increased lactic dehydrogenase value and thrombocytopenia. We suspected intravascular lymphoma, and a bone marrow aspiration smear detected malignant cells. We started chemotherapy on a diagnosis of intravascular lymphoma, which resulted in remarkable improvement of respiratory failure and pulmonary hypertension. After that, further evaluation of bone marrow specimen with immunostaining, the malignant cells were found not to be lymphoma cells but cancer cells. The primary site of the cells was not found by further investigation. Because of improvement of oxygenation and pulmonary hypertension, we performed transbronchial lung biopsy and diagnosed pulmonary tumor thrombotic microangiopathy. Here, we report this case and review previous reports.","PeriodicalId":19218,"journal":{"name":"Nihon Kokyuki Gakkai zasshi = the journal of the Japanese Respiratory Society","volume":"49 9","pages":"681-7"},"PeriodicalIF":0.0,"publicationDate":"2011-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"30244149","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[A case of drug-induced pneumonitis caused by saikokeishikankyoto]. 【saikokeishikankyoto致药物性肺炎1例】。

Nihon Kokyuki Gakkai zasshi = the journal of the Japanese Respiratory Society Pub Date : 2011-09-01

Yohhei Imai, Kozo Morimoto, Kouzou Yoshimori, Atsuyuki Kurashima, Hideo Ogata, Shoji Kudoh

引用次数: 0

[A Good syndrome associated with pure red cell aplasia]. [与纯红细胞发育不全相关的良好综合征]。

Nihon Kokyuki Gakkai zasshi = the journal of the Japanese Respiratory Society Pub Date : 2011-09-01

Tadahisa Numakura, Yoshifumi Matsuura, Hiroto Takiguchi, Yasuka Hara, Kouken Ameku

引用次数: 0

[A relapse of small-cell lung cancer ten years after concomitant chemoradiotherapy followed by high-dose chemotherapy with autologous peripheral blood stem cell transfusion]. 【小细胞肺癌同步放化疗后大剂量化疗加自体外周血干细胞输注10年复发】。

Nihon Kokyuki Gakkai zasshi = the journal of the Japanese Respiratory Society Pub Date : 2011-09-01

Akihiko Taniguchi, Nagio Takigawa, Katsuyuki Hotta, Tadashi Matsumura, Mitsune Tanimoto, Katsuyuki Kiura

{"title":"[A relapse of small-cell lung cancer ten years after concomitant chemoradiotherapy followed by high-dose chemotherapy with autologous peripheral blood stem cell transfusion].","authors":"Akihiko Taniguchi, Nagio Takigawa, Katsuyuki Hotta, Tadashi Matsumura, Mitsune Tanimoto, Katsuyuki Kiura","doi":"","DOIUrl":"","url":null,"abstract":"A 57-year-old man had limited-disease small cell lung cancer in the left lower lobe of the lung. He was treated with chemotherapy with concurrent accelerated hyperfractionated thoracic radiation, followed by high-dose chemotherapy with autologous peripheral blood stem cell transplantation. He had obtained a complete response for 10 years until the tumor in the left lower lobe was detected by positron emission tomography. Bronchoscopic brushing cytology revealed small cell cancer, which was considered to be local relapse by staging work-up. He achieved a partial response with chemotherapy consisting of cisplatin and irinotecan. The progression-free survival rate at 5 years in limited-disease small cell lung cancer ranges from 10% to 25%. Although it was difficult to distinguish the relapse of lung cancer from second primary lung cancer, we considered this case as relapse because the tumor had the same cytology in the same lobe as the previous primary tumor. The residual cells refractory to concomitant chemoradiotherapy followed by high-dose chemotherapy with stem cell transplantation had survived and proliferated after 10 years.","PeriodicalId":19218,"journal":{"name":"Nihon Kokyuki Gakkai zasshi = the journal of the Japanese Respiratory Society","volume":"49 9","pages":"697-701"},"PeriodicalIF":0.0,"publicationDate":"2011-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"30244152","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0