Nigerian journal of paediatrics最新文献_第6页

Knowledge, Attitude and Practices of Breastfeeding among mothers of children six months to three years seen at a tertiary children hospital in Freetown 在弗里敦的一家三级儿童医院，有6个月至3岁儿童的母亲的母乳喂养知识、态度和做法

Nigerian journal of paediatrics Pub Date : 2022-08-30 DOI: 10.4314/njp.v49i2.4

Ell Nellie Valerie Tayo B, Paul Ehidiamen Ikhurionan, Irene Eseohe Akhigbe, A. Mustapha, G. Ofovwe

{"title":"Knowledge, Attitude and Practices of Breastfeeding among mothers of children six months to three years seen at a tertiary children hospital in Freetown","authors":"Ell Nellie Valerie Tayo B, Paul Ehidiamen Ikhurionan, Irene Eseohe Akhigbe, A. Mustapha, G. Ofovwe","doi":"10.4314/njp.v49i2.4","DOIUrl":"https://doi.org/10.4314/njp.v49i2.4","url":null,"abstract":"Introduction Severe acute malnutrition accounts for a significant proportion of admission into the tertiary children’s hospital in Freetown. However, adequate breastfeeding is supposed to protect against severe malnutrition. Against this background, the knowledge, attitude and practice of mothers of children admitted into the hospital, were assed to determine the current state of breastfeeding in Sierra Leone. \u0000Methods: A structured questionnaire specifically designed and pretested was used to gather information on the knowledge, attitude and practice of breastfeeding of mothers with children aged 3 years and below admitted into ODCH between January and April 2021. \u0000Result: Of the 206 mothers studied, 168 (81.6%) were aged 18 to 35 years, 145 (70.4%) married. Thirty-five (17%) respondents had inadequate knowledge, while 61 (29.6%) had poor attitude and 115 (55.8%) poor practice. Factors associated with poor breastfeeding practice include age below 18 years, unmarried mothers and delivery by Caesarian section. Exclusive breastfeeding for 6 months was associated with being married (ρ-0.002). Initiation of breast feeding within 1 hour was associated with being married (ρ-0.001) and vaginal delivery (ρ-0.005) while prelacteal feeding was associated with preterm delivery (ρ-0.020). \u0000Conclusion: Despite a high prevalence of adequate knowledge among mothers of children presenting in the facility, the practice of breast feeding remain poor. There is need to provide support to mothers to appropriately carry out good breast feeding practices especially for younger and unmarried mothers and those who deliver via ceasarean section. \u0000 ","PeriodicalId":19199,"journal":{"name":"Nigerian journal of paediatrics","volume":"30 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-08-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88092768","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Comparison of point-of-care glucometers and laboratory based glucose oxidase test in determining blood glucose levels. 点护理血糖仪和实验室葡萄糖氧化酶试验测定血糖水平的比较。

Nigerian journal of paediatrics Pub Date : 2022-07-01

Babatunde Oluwatosin Ogunbosi, Olatokunbo Olumide Jarrett, Adebola Emmanuel Orimadegun, Omolola Oluwakemi Ayoola, Kike Osinusi

{"title":"Comparison of point-of-care glucometers and laboratory based glucose oxidase test in determining blood glucose levels.","authors":"Babatunde Oluwatosin Ogunbosi, Olatokunbo Olumide Jarrett, Adebola Emmanuel Orimadegun, Omolola Oluwakemi Ayoola, Kike Osinusi","doi":"","DOIUrl":"","url":null,"abstract":"Introduction: Alterations in blood glucose levels are common and an important determinant of a patient's admission outcomes, point-of-care glucometers, which are affected by a variety of factors, are increasingly used in clinical care. In this study we compared blood glucose levels determined by two commonly used glucometers (One Touch® and Accu-check®) with those of a standard laboratory method and determined the effect of haematocrit on glucose readings.Methods: Blood glucose levels were measured with One Touch® and Accu-Check® glucometers and the glucose oxidase method at the same time in 295 children aged 0 to 15 years over a 6-month period. Bland-Altman and correlation analysis were used to explore biases among the three methods. For all statistical tests, a p-value of less than 0.05 was considered statistically significant.Results: Most were males (51.2%) and the median (range) age was 1 year (1 day, 12 years). There was a significant correlation between each of the glucometer methods and laboratory blood sugar, and the correlation between the two glucometers was strong and significant. This correlation remained statistically significant even after controlling for haematocrit values. There was an acceptable level of bias (3.9 mg/dL) between the One Touch® and Accu-check® glucometers, but each had a remarkably large bias compared with the glucose oxidase method.Conclusion: The use of a tested glucometer in clinical settings can aid in rapid decision-making, but there is a need to periodically cross-check with the glucose oxidase method in the laboratory to optimise treatment outcomes for children with dysglycaemia.","PeriodicalId":19199,"journal":{"name":"Nigerian journal of paediatrics","volume":"49 3","pages":"266-271"},"PeriodicalIF":0.0,"publicationDate":"2022-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9615107/pdf/nihms-1844360.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40656908","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Challenges of caregivers and needs of children with parents in a Nigerian prison. 尼日利亚监狱中照顾者的挑战和有父母的儿童的需求。

Nigerian journal of paediatrics Pub Date : 2022-07-01

B O Ogunbosi, A A Adepoju, A E Orimadegun, G N Odaibo, O D Olaleye, O O Akinyinka

{"title":"Challenges of caregivers and needs of children with parents in a Nigerian prison.","authors":"B O Ogunbosi, A A Adepoju, A E Orimadegun, G N Odaibo, O D Olaleye, O O Akinyinka","doi":"","DOIUrl":"","url":null,"abstract":"Background: Separation of a parent from the family as a result of incarceration has both short-term and long-term effects on the family, even after release from prison. This study is a report of factors and challenges of the family left to adapt to the changed circumstances of separation from parent(s) who are incarcerated.Methods: This was a cross sectional study carried out on 89 caregivers of children whose parents are incarcerated at the Agodi prison, Ibadan who gave informed and written consent to interview their families.Results: Most caregivers had little or no formal education (69.7%) and 67.4% are into petty trading or subsistence farming. A majority of the caregivers reported the need of schooling (85.4%), provision of food (84.3%) and medical care (71.9%) as major challenges, only 25% received any form of support to meet these needs. Twenty-nine (32.6%) respondents reported receiving financial support to provide for the child's feeding. Some caregivers 21 (23.6%), obtained loans to cope with the financial needs of the children while only 3 (3.4%) received support from family or other non-governmental organisations.Conclusion: The caregivers of children of prison inmates face significant challenges in meeting the needs of feeding, health and schooling. Support structures and policies to address these gaps are required.","PeriodicalId":19199,"journal":{"name":"Nigerian journal of paediatrics","volume":"49 3","pages":"240-244"},"PeriodicalIF":0.0,"publicationDate":"2022-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9615109/pdf/nihms-1844359.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40656909","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

National School Health Policy in Nigeria; Survey of teachers’ perception and implementation in public schools in Ebonyi State 尼日利亚国家学校卫生政策;埃邦伊州公立学校教师认知与实施调查

Nigerian journal of paediatrics Pub Date : 2022-05-03 DOI: 10.4314/njp.v49i1.14

C. Ezeonu, U. Asiegbu, Cecil Eleje Arua, L. Edafioghor, A. Una, M. N. Anyansi, O. Onwe

{"title":"National School Health Policy in Nigeria; Survey of teachers’ perception and implementation in public schools in Ebonyi State","authors":"C. Ezeonu, U. Asiegbu, Cecil Eleje Arua, L. Edafioghor, A. Una, M. N. Anyansi, O. Onwe","doi":"10.4314/njp.v49i1.14","DOIUrl":"https://doi.org/10.4314/njp.v49i1.14","url":null,"abstract":"Background: The National School Health Policy (NSHP) was enacted and adopted in Nigeria in 2006 as a guide to the implementation of the School Health Programme (SHP) for the maintenance and improvement of the health of children in school.Objectives: We decided to undertake a survey of the implementation of this policy in public schools in Ebonyi state, southeast Nigeria by assessing the Head teachers' perceptions, attitude, and practice and to determine possible challenges, if any, in the policy implementation.Method: A descriptive crosssectional study was carried out on 788 public primary and secondary schools in Ebonyi state using pretested structured questionnaires administered to their head teachers. Information on school demographics, school health services; school environment, skill-based health instructions in schools and, perceived enablers or barriers toschool health implementation were retrieved.Results: About 65% of participants were unaware of the existence of the NSHP document. None of the schools reported pre-entry medical examination of students, 49.6% had no latrines, 42.1% had no source of water at school, and 45.1% had no teacher trained in Health education. Some of their perceived challenges were low awareness and commitment of school managers, the absence of health workers in school, and lack of teachers training on School Health Programme.Conclusion: Poor knowledge and understanding of the NSHP amongst the teachers, lack of basic human and material resources for health-promotion in schools may have contributed to the seemingly low attitude and practice of the NSHP in public schools of Ebonyi State, Nigeria.","PeriodicalId":19199,"journal":{"name":"Nigerian journal of paediatrics","volume":"2 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-05-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89828303","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Infant feeding knowledge and practice among HIV positive mothers attending HIV treatment centres in Lagos 拉各斯艾滋病毒治疗中心艾滋病毒阳性母亲的婴儿喂养知识和做法

Nigerian journal of paediatrics Pub Date : 2022-05-03 DOI: 10.4314/njp.v49i1.13

M. O. Odofin, F. Olatona, O. Adeniyi, Olayinka Olufumi Ayankogbe

{"title":"Infant feeding knowledge and practice among HIV positive mothers attending HIV treatment centres in Lagos","authors":"M. O. Odofin, F. Olatona, O. Adeniyi, Olayinka Olufumi Ayankogbe","doi":"10.4314/njp.v49i1.13","DOIUrl":"https://doi.org/10.4314/njp.v49i1.13","url":null,"abstract":"Background: Twenty five to forty percent of children will be infected with HIV in the absence of any form of intervention which is Prevention of Mother to Child Transmission (PMTCT).Objectives: This study determined the infant feeding knowledge and practices among HIV positive mothers attending HIV treatment centers in Lagos.Methods: A descriptive crosssectional design was used for the study. A multistage sampling technique was used to select / recruit 290 HIV positive mothers with babies between the ages of 2weeks to 18months, attending PMTCT services into the study Pre-tested interviewer administered structured questionnaire was used to collect data and analysis was done using Epi-info software. Chi-square and Fischer exact tests were used to determine association between the dependent and independent variables. The pvalue was set at 0.05.Results: Majority of the respondents (58.9%) were within the age range of 31 – 40 years and about half had a secondary school level of education. Exclusive formula feeding (40.3%) and exclusive breast feeding (42.4%) were feeding options known by the majority of the respondents. More than half (55.5%) of the mothers had a good knowledge of infant feeding options. Exclusive breastfeeding (EBF) was practiced by majority (55.5%) of the respondents, 21.4% practiced exclusive formula feeding (EFF) while only 6% practiced mixed feeding (MF). Knowledge of infant feeding options and the attitude towards exclusive breast feeding being enough in the first 6 months of life were associated with infant feeding options practiced; those with good knowledge of infant feeding options did not practice MF (9.7%) (p = 0.013).Conclusion: knowledge of infant feeding options was good and poor knowledge was associated with exclusive formula feeding. Majority practiced EBF. Educational programmes targeted at improving the knowledge of HIV and infant feeding options as well as strengthening of counseling sessions at PMTCT clinic would help reduce the risk of HIV transmission to the child.","PeriodicalId":19199,"journal":{"name":"Nigerian journal of paediatrics","volume":"105 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-05-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80685604","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Paediatric endocrine disorders at a tertiary hospital in Lagos, Nigeria 尼日利亚拉各斯一家三级医院的儿科内分泌紊乱

Nigerian journal of paediatrics Pub Date : 2022-05-03 DOI: 10.4314/njp.v49i1.12

I. Akinola, Akpojeme Ovwighuo Afiemo, P. Ubuane, O. Odusote

{"title":"Paediatric endocrine disorders at a tertiary hospital in Lagos, Nigeria","authors":"I. Akinola, Akpojeme Ovwighuo Afiemo, P. Ubuane, O. Odusote","doi":"10.4314/njp.v49i1.12","DOIUrl":"https://doi.org/10.4314/njp.v49i1.12","url":null,"abstract":"Background: The global increase in paediatric endocrine disorders (PED) is thought to be a result of multiple factors including changing lifestyles, environmental pollution and increasing awareness and diagnostic capabilities. Studies on the prevalence of paediatric endocrine disorders in the developing world are few. A preliminary audit of PED at the Lagos State University Teaching Hospital two years ago revealed type 1 diabetes mellitus as the commonest diagnosis. Since then many more children with PED continue to be referred from various centres.Objective: The aim of the present study was to describe the burden and pattern paediatric endocrine disorders over a three-year period.Subjects and Methods: Records of patients who presented in the paediatric endocrine unit between March 2017 and March 2020 were reviewed and relevant data on age at presentation, sex and diagnosis were extracted.Results: A total of 172 patients representing 0.45% of the total paediatric patients seen within the period. There were more females 90(52.3%) than males 79(45.9%) and three patients (1.7%) presented with disorders of sexual differentiation. Age of presentation ranged between 11 days and 16 years with mean of 6.27 ± 4.5 years. The commonest groups of endocrine disorders were disorders of pancreas/lipids-diabetes (n=33, 19.2%), pubertal disorders (n=25, 14.5%) and thyroid disorders (n=24, 14.0%).Conclusion: Our unit witnessed a comparatively larger case-load of PEDs compared to earlier reports from other parts of Nigeria. Diabetes mellitus, pubertal and thyroid disorders constituted the commonest paediatric endocrine disorders encountered.","PeriodicalId":19199,"journal":{"name":"Nigerian journal of paediatrics","volume":"49 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-05-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84547130","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

Zinc phosphide (rodenticide) poisoning: A case report of deliberate self-harm in an eleven-year-old 磷化锌(灭鼠剂)中毒:11岁儿童故意自残一例报告

Nigerian journal of paediatrics Pub Date : 2022-05-03 DOI: 10.4314/njp.v49i1.15

A. Adepoju, A. Asinobi, A. Ademola, O. Akinyinka, Olutosin Abioye, Adesola O. Adelaja, Philip O Robert

{"title":"Zinc phosphide (rodenticide) poisoning: A case report of deliberate self-harm in an eleven-year-old","authors":"A. Adepoju, A. Asinobi, A. Ademola, O. Akinyinka, Olutosin Abioye, Adesola O. Adelaja, Philip O Robert","doi":"10.4314/njp.v49i1.15","DOIUrl":"https://doi.org/10.4314/njp.v49i1.15","url":null,"abstract":"Zinc Phosphide(Zn3P2) is a common rodenticide freely available in Nigeria for use against rodents. Occasionally human consumption occurs either accidentally or intentionally with potential consequences of multiorgan toxicity and death. An 11-year-old boy consumed an unknown quantity of zinc phosphide marketed as Push Out® with the intention of committing suicide and killing some members of the family as his response to chastisement for a misdemeanour. Patient presented in the hospital 4 days after ingestion of zinc phosphide with a history of profound vomiting and abdominal pain. Laboratory evaluation showed evidence of hepatic dysfunction, acute kidney injury and elevated serum amylase. He was managed conservatively and discharged home after two weeks of admission. We report this case to emphasise the need for Paediatricians to consider ingestion of rodenticides as a differential diagnosis of hepatoxicity and pancreatic enzyme elevation, as well as to highlight the possibility of suicide among children. There is need to control the indiscriminate use of rodenticides, strengthen public health education on poisoning as well as establish Poison Information Centres in our environment.","PeriodicalId":19199,"journal":{"name":"Nigerian journal of paediatrics","volume":"155 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-05-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89043736","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Assessment of knowledge on Lassa fever disease among caregivers presenting to a tertiary Institution in a Lassa fever endemic region, Southeast Nigeria 评估尼日利亚东南部拉沙热流行区某高等教育机构护理人员对拉沙热的知识

Nigerian journal of paediatrics Pub Date : 2022-05-02 DOI: 10.4314/njp.v49i1.9

M. Orji, D. Obu, U. Asiegbu

{"title":"Assessment of knowledge on Lassa fever disease among caregivers presenting to a tertiary Institution in a Lassa fever endemic region, Southeast Nigeria","authors":"M. Orji, D. Obu, U. Asiegbu","doi":"10.4314/njp.v49i1.9","DOIUrl":"https://doi.org/10.4314/njp.v49i1.9","url":null,"abstract":"Background: Lassa fever disease is an infectious disease with high case fatality occurring in countries in West, Central, and East Africa. It is endemic in Nigeria and Ebonyi State, Southeast Nigeria. Knowledge of the cause, mode of transmission, and clinical presentations are invaluable in disease prevention and control.Objective: The study was therefore aimed at assessing the level of knowledge of Lassa fever disease among caregivers that presented at children out-patient in a tertiary hospital in Ebonyi State.Methods: It was a hospital-based cross-sectional study carried out within 6 months (May-October 2018 ) . An Interviewer - administered questionnaire was used to obtain information on socio-demographics and level of knowledge on Lassa fever disease.Results: Although 356 (92.7%) of the 384 respondents have heard of Lassa fever disease, only 205 (53.4%) had good knowledge of the disease. The mean age of participants was 33.22 ± 7.53; male to female ratio 1:2.4. Respondents within 36 and 45 years were rated highest (65.0%) in good knowledge of the disease. More males (61.9%) than females (49.8%) knew about Lassa fever disease. Similarly, caregivers (67.7%) from the upper socioeconomic class had better knowledge of the disease compared to 43.0% observed among their colleagues in the lower socioeconomic class. There were significant relationships between knowledge of Lassa fever disease and age (p= 0.026), gender (p=0.030), and socio-economic class (p< 0.001).Conclusion: There is a huge gap in knowledge of Lassa fever disease among participants especially among female caregivers and those of lower socio-economic class. Public enlightenment on Lassa fever disease should be intensified in these groups of people ","PeriodicalId":19199,"journal":{"name":"Nigerian journal of paediatrics","volume":"363 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-05-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76573325","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Sickle cell disease: caregiver’s awareness and phenotype distribution among children presenting to children emergency of a tertiary hospital in Lagos, Nigeria 镰状细胞病:尼日利亚拉各斯一家三级医院急诊儿童护理人员的认识和表型分布

Nigerian journal of paediatrics Pub Date : 2022-05-02 DOI: 10.4314/njp.v49i1.10

E. Oluwole, T. Adeyemo, B. Osinaike, P. Akintan

{"title":"Sickle cell disease: caregiver’s awareness and phenotype distribution among children presenting to children emergency of a tertiary hospital in Lagos, Nigeria","authors":"E. Oluwole, T. Adeyemo, B. Osinaike, P. Akintan","doi":"10.4314/njp.v49i1.10","DOIUrl":"https://doi.org/10.4314/njp.v49i1.10","url":null,"abstract":"Background: Sickle cell disease accounts for significant morbidity and mortality in sub-Saharan Africa and the burden is expected to increase further by 2050. Nigeria is known to bear the highest burden of sickle cell disease in the world with about 2.69–5% of the population affected by the disease.Aim: This study determined awareness of sickle cell disease among caregivers and phenotype distribution of children presenting to children emergency in Lagos University Teaching Hospital (LUTH), Nigeria.Methods: The study was crosssectional and descriptive in design and data was collected using a pretested, structured intervieweradministered questionnaire among 250 caregivers and children. HemoTypeSC™ rapid test kit was used to determine the hemoglobin phenotype in whole blood of the respondents who were consecutively recruited following the caregiver’s consent. The Statistical Package for Social Sciences version 21 software was used for analysis.Univariate and bivariate analyses were carried out with a level of significance set at p ≤ 0.05.Results: The mean age of the children was 50.27±50.91 months. There were more females 141 (56.4%) than males. Almost all 242 (96.8%) caregivers did not know the children’s Hb phenotype. Most 173 (69.2%) of the children had HbAA;55(22.0%) were HbAS; 6(2.4%) were HbAC; 15 and 1 (6.0% and 0.4%) were HbSS and HbSCphenotypes respectively. Education was statistically significant with awareness of SCD (p=0.002) and awareness of SCD was statistically significant with knowledge of prevention (p<0.001) among the caregivers.Conclusion: Awareness of SCD among the caregivers of children was high, although the majority of them did not know the children’s Hb phenotype. Most of the children had HbAA with a high proportion of HbSS and HbSC phenotypes. A routine neonatal/early infant screening program for SCD is highly recommended in Nigeria for early diagnosis and prevention of SCD complications.","PeriodicalId":19199,"journal":{"name":"Nigerian journal of paediatrics","volume":"16 Suppl 3 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-05-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83556002","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Use of serum levels of selected enzymes as a supportive tool in assessing severity of birth asphyxia in low resource setting 在低资源环境中，使用选定的血清酶水平作为评估出生窒息严重程度的辅助工具

Nigerian journal of paediatrics Pub Date : 2022-05-02 DOI: 10.4314/njp.v49i1.11

T. Ogundele, S. B. Oseni, J. Owa

{"title":"Use of serum levels of selected enzymes as a supportive tool in assessing severity of birth asphyxia in low resource setting","authors":"T. Ogundele, S. B. Oseni, J. Owa","doi":"10.4314/njp.v49i1.11","DOIUrl":"https://doi.org/10.4314/njp.v49i1.11","url":null,"abstract":"Introduction: Severe birth asphyxia is one of the reasons why babies are admitted into the newborn unit and contributing significantly to neonatal morbidity and mortality. Hypoxic injury, when severe, leads to leakage of intracellular enzymes into the circulation. The level of these enzymes reflects the severity of the damage; this can identify babies with a severe injury, especially the out borns whose deliveries were not supervised. This study aimed to relate the serum levels of three enzymes at the age of twelve hours to the severity of birth asphyxia using the Apgar score and neurological state of the babies.Methods: A prospective comparative cross-sectional study. Term babies with Apgar score ˂ 7 at 1-minute of life were recruited, scores of 0-3 were taken as severe birth asphyxia. Serum levels of lactate dehydrogenase, aspartate aminotransferase, and alanine aminotransferase, were determined at the age of 12 hours using an ultraviolet spectrophotometer. Levels of the enzymes were related to the severity of birth asphyxia. SPSS for Windows, version 18 was used to analyse the dataResults: Seventy babies with birth asphyxia and 70 controls were studied. Fifteen (41.7%) of the 36 babies with severe birth asphyxia had hypoxic-ischemic encephalopathy, four (5.7%) of which died. The mean values of each of the enzymes were higher in babies with hypoxic-ischaemic encephalopathy than in those without (p = 0.001), and in babies that died than babies that survived (p = 0.001).Conclusion: Estimation of these enzymes clearly defines the severity of hypoxic injury in babies with birth asphyxia. The estimation of these enzymes will be a useful tool in identifying babies with birth asphyxia especially in outborns whose deliveries were not supervised.","PeriodicalId":19199,"journal":{"name":"Nigerian journal of paediatrics","volume":"54 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-05-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84717796","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0