Nihon Ika Daigaku zasshi最新文献_第6页

Effect of age on urinary excretion of N-acetyl-beta-D-glucosaminidase. 年龄对尿中n -乙酰- β - d -氨基葡萄糖苷酶的影响。

Nihon Ika Daigaku zasshi Pub Date : 1999-02-01 DOI: 10.1272/jnms.66.33

K Oba, M Hirai, Y Ajiro, K Okazaki, S Sato, K Sasai, T Suzuki, H Nakano, S Metori

{"title":"Effect of age on urinary excretion of N-acetyl-beta-D-glucosaminidase.","authors":"K Oba, M Hirai, Y Ajiro, K Okazaki, S Sato, K Sasai, T Suzuki, H Nakano, S Metori","doi":"10.1272/jnms.66.33","DOIUrl":"https://doi.org/10.1272/jnms.66.33","url":null,"abstract":"To examine the relationship between the concentrations of urinary NAG and age, we measured ratios of urinary N-acetyl-beta-D-glucosaminidase (NAG) to urinary creatinine (NAG index) in 137 healthy subjects, aged from 19 to 88 years. The study is also designed to evaluate the relationship between urinary NAG and blood pressure. The subjects were divided into 7 subgroups, according to their age (< 30, 30-39, 40-49, 50-59, 60-69, 70-79, 80 or more years). There was a positive correlation between NAG index and age (r = 0.36; P < 0.001). The regression equation relating NAG index (y) to age (x) was y = 0.065x + 0.97. The mean NAG indexes for the 7 subgroups divided by age were significantly different (P < 0.01). There was a positive correlation between NAG index and systolic blood pressure (r = 0.18; P < 0.05), but was not between diastolic blood pressure and NAG index. In multiple regression analysis, age and BUN significantly correlated with NAG index (r = 0.32; P < 0.01, r = 3.3; P = 0.07, respectively), although there was no correlation between systolic blood pressure and NAG index. This cross-sectional study showed a clear elevation in NAG index with age. The rate of elevation was 0.65 per decade. Urinary excretion of NAG may be unrelated to blood pressure.","PeriodicalId":19192,"journal":{"name":"Nihon Ika Daigaku zasshi","volume":"66 1","pages":"33-6"},"PeriodicalIF":0.0,"publicationDate":"1999-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1272/jnms.66.33","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"20969423","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 11

[Metastatic brain tumor]. [转移性脑瘤]。

Nihon Ika Daigaku zasshi Pub Date : 1999-02-01 DOI: 10.1272/jnms.66.56

F Yamaguchi, H Takahashi, A Teramoto

引用次数: 16

Modified Fontan operation. Considerations for the determination of the appropriate procedure. 修改方探操作。确定适当程序的考虑因素。

Nihon Ika Daigaku zasshi Pub Date : 1999-02-01 DOI: 10.1272/jnms.66.28

H Yamauchi, Y Ishii, H Omori, Y Takakusaki, K Yamada, T Yajima, T Nitta, M Ochi, D Fukumi, Y Kuramochi, T Okubo, S Ogawa, S Tanaka

{"title":"Modified Fontan operation. Considerations for the determination of the appropriate procedure.","authors":"H Yamauchi, Y Ishii, H Omori, Y Takakusaki, K Yamada, T Yajima, T Nitta, M Ochi, D Fukumi, Y Kuramochi, T Okubo, S Ogawa, S Tanaka","doi":"10.1272/jnms.66.28","DOIUrl":"https://doi.org/10.1272/jnms.66.28","url":null,"abstract":"Background: Although the surgical results of the modified Fontan operation continues to improve, there are various advantages and disadvantages in terms of the post operative condition associated with the Fontan modifications. Late morbidity and mortality are mainly due to arrhythmias, thromboembolic complications, systemic venous hypertension and infective endocarditis. We reported our experience of the modified Fontan operation to determine an appropriate procedure for each patient.Methods and results: Seven patients (ranging from the age 1-14 years) underwent a modified Fontan operation including a lateral tunnel (n = 1), extracardiac conduit (n = 2) and autogenous atrial tunnel (n = 4). There was one hospital death due to sepsis in which the patient underwent lateral tunnel procedure. The mean follow up of another six patients was 20 months (ranging from 1-39 months) and all patients were classified as NYHA class I, and remained in normal sinus rhythm without any thromboembolic complications.Conclusions: When using the autogenous atrial tunnel, there are potential advantages; it is not associated with thromboembolism or endocarditis and has growth potential. However, in high-risk patients with increased pulmonary vascular resistance, impaired ventricular function and pre-operative atrial arrhythmias, it appears reasonable to use an extracardiac conduit.","PeriodicalId":19192,"journal":{"name":"Nihon Ika Daigaku zasshi","volume":"66 1","pages":"28-32"},"PeriodicalIF":0.0,"publicationDate":"1999-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"20969422","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Fibroin allergy. IgE mediated hypersensitivity to silk suture materials. 蚕丝蛋白过敏。IgE介导的丝缝线材料过敏。

Nihon Ika Daigaku zasshi Pub Date : 1999-02-01 DOI: 10.1272/jnms.66.41

S Kurosaki, H Otsuka, M Kunitomo, M Koyama, R Pawankar, K Matumoto

引用次数: 98

[Induction of noradrenergic supersensitivity following cordotomy in neonatal rat spinal motoneurons]. [脊髓切开术诱导新生大鼠脊髓运动神经元去甲肾上腺素能超敏感]。

Nihon Ika Daigaku zasshi Pub Date : 1999-02-01 DOI: 10.1272/jnms.66.21

H Kadotani

{"title":"[Induction of noradrenergic supersensitivity following cordotomy in neonatal rat spinal motoneurons].","authors":"H Kadotani","doi":"10.1272/jnms.66.21","DOIUrl":"https://doi.org/10.1272/jnms.66.21","url":null,"abstract":"Patients with spinal cord lesions frequently show autonomic hyperreflexia. The mechanism of autonomic hyperreflexia has been thought to be an acute general autonomic overactivity in response to cutaneous or visceral stimuli, but it remains uncertain. Several kinds of experiments suggest that amplified spinal sympathetic reflexes in the decentralized cord are attributable to the denervation supersensitivity of denervated neurons, which is a well-known phenomenon in denervated muscle fibers. In the present study, changes in the supersensitivity of motoneurons after cordotomy were studied in the spinal cord of neonatal rats. Responses to bath-applied noradrenaline (NA) were recorded from a ventral root of the isolated spinal cord of 6-day-old rats. In normal spinal cords, NA induced depolarization in motoneurons dose-dependently. alpha 1-antagonist prazosin (3 microM) inhibited the deporalization induced by NA, and alpha 2-antagonist rauwolscine (1 microM) potentiated it. In one group of rats, cordotomy was performed 4 days after birth by complete transection of the spinal cord at vertebrate 8th-10th thoracic level, and NA response was examined two days later (when they were 6 days old). In cordotomized rats, NA-induced depolarization was increased with respect to both amplitude and duration. alpha 1- as well as alpha 2-antagonists inhibited the NA response in the spinalized rats. Especially, both antagonists shortened the duration of NA response as compared to normal level. It is concluded that the denervation supersensitivity to NA appears 2 days after cordotomy in the spinal motoneurons of neonatal rats and that the supersensitivity to NA is attributable to the upregulation of both alpha 1- and alpha 2-adrenoceptors on the motoneurons, indicating that a new type of alpha 2-adrenoceptor function appears.","PeriodicalId":19192,"journal":{"name":"Nihon Ika Daigaku zasshi","volume":"66 1","pages":"21-7"},"PeriodicalIF":0.0,"publicationDate":"1999-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"20969421","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Spontaneous gastrointestinal perforation in patients with lymphoma receiving chemotherapy and steroids. Report of three cases. 接受化疗和类固醇治疗的淋巴瘤患者的自发性胃肠道穿孔。报告三例病例。

Nihon Ika Daigaku zasshi Pub Date : 1999-02-01 DOI: 10.1272/jnms.66.37

M Wada, M Onda, A Tokunaga, T Kiyama, T Yoshiyuki, N Matsukura, K Furukawa, K Egami, K Yamashita

{"title":"Spontaneous gastrointestinal perforation in patients with lymphoma receiving chemotherapy and steroids. Report of three cases.","authors":"M Wada, M Onda, A Tokunaga, T Kiyama, T Yoshiyuki, N Matsukura, K Furukawa, K Egami, K Yamashita","doi":"10.1272/jnms.66.37","DOIUrl":"https://doi.org/10.1272/jnms.66.37","url":null,"abstract":"Spontaneous gastrointestinal perforations in three patients with lymphoma were considered to be treatment-related conditions. All three were diagnosed as having malignant lymphoma by histological examination, and treated with chemotherapy and steroids. Four to 14 days after the start of chemotherapy, they complained of abdominal pain and plain roentgenograms revealed pneumoperitoneum. The interval between the onset of peritonitis and operation was almost 24 h. Emergency operations were carried out; one patient with a jejunal perforation underwent resection of the jejunum, another with a gastric perforation received a simple closure with omental patch, and the third with a gastric perforation underwent gastrectomy. Two patients recovered from the surgery, while the gastrectomy patient died due to sepsis. The favorable outcome of the surgical intervention is attributed to early diagnosis, prompt exploration, and selective operative procedures. We recommended a simple closure with omental patch for gastroduodenal perforation. Resection and primary anastomosis are possible only in the small bowel.","PeriodicalId":19192,"journal":{"name":"Nihon Ika Daigaku zasshi","volume":"66 1","pages":"37-40"},"PeriodicalIF":0.0,"publicationDate":"1999-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1272/jnms.66.37","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"20969276","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 36

Effects of temperature and preservation time on the pharmacological response of isolated vascular endothelial and smooth muscle function. 温度和保存时间对离体血管内皮和平滑肌功能药理反应的影响。

Nihon Ika Daigaku zasshi Pub Date : 1999-02-01 DOI: 10.1272/jnms.66.15

H Iwaki, A Sakamoto, S Tanaka

{"title":"Effects of temperature and preservation time on the pharmacological response of isolated vascular endothelial and smooth muscle function.","authors":"H Iwaki, A Sakamoto, S Tanaka","doi":"10.1272/jnms.66.15","DOIUrl":"https://doi.org/10.1272/jnms.66.15","url":null,"abstract":"In clinical transplantation and cardiovascular surgery, cold preservation is usually used because it is a simple method. However, the established temperature is by no means exact. The aim of this study was to find the optimum storage temperature for preservation of the vasculature by observing the pharmacological endothelium and smooth muscle response. The thoracic aorta of 36 male Wister rats were studied in organ baths: as fresh control after 24 hours, 48 hours and 72 hours of storage at 0.5 degree C, 4 degrees C and 8 degrees C in Krebs-Henseleit bicarbonate (KHB) solution. Acetylcholine (Ach) was used to elicit endothelium-dependent relaxation, and sodium nitroprusside (SNP) to elicit smooth muscle-dependent relaxation. The contractility caused by Phenylephrine (Ph) was influenced by time but before 48 hours it was not influenced by preservation temperature. Significant responsive deterioration by Ach and SNP was seen after 24 hours of storage at 0.5 degree C as compared with storage at 4 degrees C. The endothelium-dependent relaxing function and smooth muscle-dependent relaxing function were best preserved at 4 degrees C and 8 degrees C. These results indicate that precise temperature control is necessary for vessel preservation in clinical situations.","PeriodicalId":19192,"journal":{"name":"Nihon Ika Daigaku zasshi","volume":"66 1","pages":"15-20"},"PeriodicalIF":0.0,"publicationDate":"1999-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"20969420","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 5

[Treatments for vascular dementia and Alzheimer's disease]. [血管性痴呆和阿尔茨海默病的治疗方法]。

Nihon Ika Daigaku zasshi Pub Date : 1999-02-01 DOI: 10.1272/jnms.66.52

S Kitamura

引用次数: 1

[Clinical features and management of elderly patients with dementia]. 【老年痴呆患者的临床特点及处理】。

Nihon Ika Daigaku zasshi Pub Date : 1999-02-01 DOI: 10.1272/jnms.66.49

M Kimura

引用次数: 0

[DNA bend sites in the promoter region of the human estrogen receptor alpha gene]. [人类雌激素受体α基因启动子区域的DNA弯曲位点]。

Nihon Ika Daigaku zasshi Pub Date : 1998-12-01 DOI: 10.1272/jnms1923.65.459

K Kuwabara, Y Sakuma

引用次数: 0