L. Kish, M. Cheng, Jong U. Kim, S. Seo, M. King, R. Young, A. Dér, G. Schmera
{"title":"ESTIMATION OF DETECTION LIMITS OF THE PHAGE-INVASION BASED IDENTIFICATION OF BACTERIA","authors":"L. Kish, M. Cheng, Jong U. Kim, S. Seo, M. King, R. Young, A. Dér, G. Schmera","doi":"10.1142/S0219477505002458","DOIUrl":"https://doi.org/10.1142/S0219477505002458","url":null,"abstract":"Recently a new method, SEnsing of Phage-Triggered Ion Cascade (SEPTIC) was proposed for the rapid detection and identification of bacteria via the electrical field caused by the stochastic emission of ions during phage infection. In this Letter, we present linear network theoretical considerations about the detection limits of the method. The considerations are based on our published data of the E. coli detection experiments and on the assumption of a linear response between the number of bacteria and the measured power density spectrum of the fluctuation-signal. Some practical limits of the detectability of the present agents with possible noise measurement arrangements are discussed in this paper. The calculations indicate that the detection and identification of a single bacterium can be achieved with natural (wild) phages with reasonable efforts within a time window of 10 minutes.","PeriodicalId":191232,"journal":{"name":"The Random and Fluctuating World","volume":"24 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2005-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116538668","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"QUANTUM ERROR CORRECTION FAILS FOR HAMILTONIAN MODELS","authors":"R. Alicki","doi":"10.1142/S0219477506003343","DOIUrl":"https://doi.org/10.1142/S0219477506003343","url":null,"abstract":"It is argued that the existing schemes of fault-tolerant quantum computation designed for discrete-time models and based on quantum error correction fail for continuous-time Hamiltonian models even with Markovian noise.","PeriodicalId":191232,"journal":{"name":"The Random and Fluctuating World","volume":"63 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2004-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133550372","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
C. Ciofi, G. Giusi, G. Scandurra, Salita Sperone, B. Neri
{"title":"DEDICATED INSTRUMENTATION FOR HIGH SENSITIVITY, LOW FREQUENCY NOISE MEASUREMENT SYSTEMS","authors":"C. Ciofi, G. Giusi, G. Scandurra, Salita Sperone, B. Neri","doi":"10.1142/S0219477504001963","DOIUrl":"https://doi.org/10.1142/S0219477504001963","url":null,"abstract":"Low Frequency Noise Measurements (LFNM) can be used as very sensitive tool for the characterization o f the quality and the reliability of electron devices. However, especially in those cases in which the frequency range of interest extends below 1 Hz, instrumentation with an acceptable low level of background noise is not e asily found on the market. In fact, at very low frequencies, the flicker noise introduced by the electronic components which make up the instrumentation becomes predominant and several interesting phenomena which could be detected by means of LFNM may result completely hidden in the background noise. This consideration is not limited to the case of input preamplifiers but does extend to any piece of instrumentation that contributes to the LFNM systems, and in particular to the power supplies used for biasing the Device Under Test. During the last few years, our research groups have been strongly involved in the design of very low noise instrumentation for application in the field of LFNM. In this work we report the main results which we have ob tained together w ith a discussion of the d esign guidelines that have a llowed us, in a few cases, to reach noise levels not to be equalled by any instrumentation available on the market.","PeriodicalId":191232,"journal":{"name":"The Random and Fluctuating World","volume":"62 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2004-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121086028","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
G. Schmid, I. Goychuk, P. Hänggi, S. Zeng, P. Jung
{"title":"STOCHASTIC RESONANCE AND OPTIMAL CLUSTERING FOR ASSEMBLIES OF ION CHANNELS","authors":"G. Schmid, I. Goychuk, P. Hänggi, S. Zeng, P. Jung","doi":"10.1142/S0219477504001628","DOIUrl":"https://doi.org/10.1142/S0219477504001628","url":null,"abstract":"We consider the statistical properties of action potentials generated by clusters of sodium and potassium channels due to channel noise and/or external stimulation. Since the fluctuations are related to the cluster size, a size-resonance effect — analog to stochastic resonance — is observed that facilitates optimal decoding of small external stimuli at optimal cluster sizes. Furthermore, in analogy to the coherence resonance effect, the channel-noise induced firing patterns exhibit a resonant-like temporal coherence as a function of the cluster size even in the absence of a periodic stimulus. In the presence of additional synaptic noise, SR occurs only for large cluster sizes which possess suboptimal internal noise levels.","PeriodicalId":191232,"journal":{"name":"The Random and Fluctuating World","volume":"21 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2004-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133716778","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"SYNCHRONIZATION APPROACH TO ANALYSIS OF BIOLOGICAL SYSTEMS","authors":"M. Rosenblum, A. Pikovsky, J. Kurths","doi":"10.1142/S0219477504001653","DOIUrl":"https://doi.org/10.1142/S0219477504001653","url":null,"abstract":"In this article we review the application of the synchronization theory to the analysis of multivariate biological signals. We address the problem of phase estimation from data and detection and quantification of weak interaction, as well as quantification of the direction of coupling. We discuss the potentials as well as limitations and misinterpretations of the approach.","PeriodicalId":191232,"journal":{"name":"The Random and Fluctuating World","volume":"53 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2004-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133426332","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"NOISE ANALYSIS IN STUDIES OF PROTEIN DYNAMICS AND MOLECULAR TRANSPORT","authors":"S. Bezrukov","doi":"10.1142/S0219477504001641","DOIUrl":"https://doi.org/10.1142/S0219477504001641","url":null,"abstract":"Understanding the role of noise at cellular and higher hierarchical levels depends on our knowledge of the physical mechanisms of its generation. Conversely, noise is a rich source of information about these mechanisms. Using channel-forming protein molecules reconstituted into artificial 5-nm-thick insulating lipid films, it is possible to investigate noise in single-molecule experiments and to relate its origins to protein function. Recent progress in this field is reviewed with an emphasis on how this experimental technique can be used to study low-frequency protein dynamics, including not only reversible ionization of sites on the channel-forming protein molecule, but also molecular mechanisms of 1/f-noise generation. Several new applications of the single-molecule noise analysis to membrane transport problem are also addressed. Among those is a study on antibiotic translocation across bacterial walls. High-resolution recording of ionic current through the single channel, formed by the general bacterial porin, OmpF, enables us to resolve single-molecule events of antibiotic translocation.","PeriodicalId":191232,"journal":{"name":"The Random and Fluctuating World","volume":"83 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2004-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130316873","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"CLASSICAL TELEPORTATION OF CLASSICAL STATES","authors":"O. Cohen","doi":"10.1142/S0219477506003240","DOIUrl":"https://doi.org/10.1142/S0219477506003240","url":null,"abstract":"The standard quantum teleportation scheme is deconstructed, and those aspects of it that appear remarkable and \"non-classical\" are identified. An alternative teleportation scheme, involving only classical states and classical information, is then formulated, and it is shown that the classical scheme reproduces all of these remarkable aspects, despite the fact that they had seemed non-classical. This leads to a re-examination of quantum teleportation, which suggests that its significance depends on the interpretation of quantum states.","PeriodicalId":191232,"journal":{"name":"The Random and Fluctuating World","volume":"65 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2003-10-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121301465","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
B. Suki, A. Alencar, U. Frey, P. Ivanov, S. Buldyrev, A. Majumdar, H. Stanley, C. Dawson, G. Krenz, M. Mishima
{"title":"FLUCTUATIONS, NOISE AND SCALING IN THE CARDIO-PULMONARY SYSTEM","authors":"B. Suki, A. Alencar, U. Frey, P. Ivanov, S. Buldyrev, A. Majumdar, H. Stanley, C. Dawson, G. Krenz, M. Mishima","doi":"10.1142/S0219477503001142","DOIUrl":"https://doi.org/10.1142/S0219477503001142","url":null,"abstract":"The structure and the functioning of cardio-pulmonary system is complex and statistical physics appear to be suitable for their characterization. In this review, we examine scaling in cardio-pulmonary physiology. The focus will be on the interpretation of scaling behaviors and their relation to structure-function in the normal and diseased cardio-pulmonary system. First, we overview fluctuations and scaling in respiratory rate variability in terms of a neural network model. Next, we analyze fluctuations in human heartbeat dynamics under healthy and pathologic conditions using wavelets and multifractal approaches. We then discuss avalanche behavior of airway openings as well as scaling behavior of crackling sound generated during the process of airway openings. We also examine the relationship between the observed scaling properties and the design features of the pulmonary vascular tree. Finally, we show how the network failure of lung tissue structure leads to emphysema, a leading cause of respiratory dis...","PeriodicalId":191232,"journal":{"name":"The Random and Fluctuating World","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2003-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129703082","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"THE APPLICATION OF SUPRATHRESHOLD STOCHASTIC RESONANCE TO COCHLEAR IMPLANT CODING","authors":"N. Stocks, D. Allingham, R. Morse","doi":"10.1142/S0219477502000774","DOIUrl":"https://doi.org/10.1142/S0219477502000774","url":null,"abstract":"In this paper we explore the possibility of using a recently discovered form of stochastic resonance - termed suprathreshold stochastic resonance - to improve speech comprehension in patients fitted with cochlear implants. A leaky-integrate-and-fire (LIF) neurone is used to model cochlear nerve activity when subject to electrical stimulation. This model, in principle, captures key aspects of temporal coding in analogue cochlear implants. Estimates for the information transmitted by a population of nerve fibres is obtained as a function of internal (neuronal) noise level. We conclude that SSR does indeed provide a possible mechanism by which information transmission along the cochlear nerve can be improved - and thus may well lead to improved speech comprehension.","PeriodicalId":191232,"journal":{"name":"The Random and Fluctuating World","volume":"4 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2002-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126124466","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"SIGNAL-TO-NOISE RATIO GAIN IN NON-DYNAMICAL AND DYNAMICAL BISTABLE STOCHASTIC RESONATORS","authors":"P. Makra, Z. Gingl, L. Kish","doi":"10.1142/S0219477502000750","DOIUrl":"https://doi.org/10.1142/S0219477502000750","url":null,"abstract":"It has recently been reported that in some systems showing stochastic resonance, the signal-to-noise ratio (SNR) at the output can significantly exceed that at the input; in other words, SNR gain is possible. We took two such systems, the non-dynamical Schmitt trigger and the dynamical double wellpotential, and using numerical and mixed-signal simulation techniques, we examined what SNR gains these systems can provide. In the non-linear response limit, we obtained SNR gains much greater than unity for both systems. In addition to the classical narrow-band SNR definition, we also measured the ratio of the total power of the signal to the power of the noise part, and it showed even better signal improvement. Here we present a brief review of our results, and scrutinise, for both the Schmitt-trigger and the double well potential, the behaviour of the SNR gain by stochastic resonance for different signal amplitudes and duty cycles. We also discuss the mechanism of providing gains greater than unity.","PeriodicalId":191232,"journal":{"name":"The Random and Fluctuating World","volume":"2016 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2002-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127363629","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}