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Molecular biology, biochemistry, and biophysics最新文献

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Coupled oscillator theory of enzyme action. 酶作用的耦合振荡器理论。
Molecular biology, biochemistry, and biophysics Pub Date : 1980-01-01 DOI: 10.1007/978-3-642-81503-4_7
M D Williams, J L Fox
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引用次数: 2
Three multifunctional protein kinase systems in transmembrane control. 跨膜控制中的三种多功能蛋白激酶系统。
Molecular biology, biochemistry, and biophysics Pub Date : 1980-01-01 DOI: 10.1007/978-3-642-81503-4_9
Y Nishizuka
{"title":"Three multifunctional protein kinase systems in transmembrane control.","authors":"Y Nishizuka","doi":"10.1007/978-3-642-81503-4_9","DOIUrl":"https://doi.org/10.1007/978-3-642-81503-4_9","url":null,"abstract":"","PeriodicalId":19093,"journal":{"name":"Molecular biology, biochemistry, and biophysics","volume":"32 ","pages":"113-35"},"PeriodicalIF":0.0,"publicationDate":"1980-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17317979","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 51
Regulation of muscle contraction by Ca ion. 钙离子对肌肉收缩的调节。
Molecular biology, biochemistry, and biophysics Pub Date : 1980-01-01 DOI: 10.1007/978-3-642-81503-4_14
S Ebashi, Y Nonomura, K Kohama, T Kitazawa, T Mikawa
{"title":"Regulation of muscle contraction by Ca ion.","authors":"S Ebashi, Y Nonomura, K Kohama, T Kitazawa, T Mikawa","doi":"10.1007/978-3-642-81503-4_14","DOIUrl":"https://doi.org/10.1007/978-3-642-81503-4_14","url":null,"abstract":"","PeriodicalId":19093,"journal":{"name":"Molecular biology, biochemistry, and biophysics","volume":"32 ","pages":"183-94"},"PeriodicalIF":0.0,"publicationDate":"1980-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17175510","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 19
Structural and dynamic aspects of recognition between tRNAs and aminoacyl-tRNA synthetases. trna和氨基- trna合成酶之间识别的结构和动态方面。
Molecular biology, biochemistry, and biophysics Pub Date : 1980-01-01 DOI: 10.1007/978-3-642-81503-4_22
D G Knorre, V V Vlassov
{"title":"Structural and dynamic aspects of recognition between tRNAs and aminoacyl-tRNA synthetases.","authors":"D G Knorre, V V Vlassov","doi":"10.1007/978-3-642-81503-4_22","DOIUrl":"https://doi.org/10.1007/978-3-642-81503-4_22","url":null,"abstract":"","PeriodicalId":19093,"journal":{"name":"Molecular biology, biochemistry, and biophysics","volume":"32 ","pages":"278-300"},"PeriodicalIF":0.0,"publicationDate":"1980-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18052027","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 5
On codon- anticodon interactions. 关于密码子-反密码子相互作用。
Molecular biology, biochemistry, and biophysics Pub Date : 1980-01-01 DOI: 10.1007/978-3-642-81503-4_27
H Grosjean, H Chantrenne
{"title":"On codon- anticodon interactions.","authors":"H Grosjean, H Chantrenne","doi":"10.1007/978-3-642-81503-4_27","DOIUrl":"https://doi.org/10.1007/978-3-642-81503-4_27","url":null,"abstract":"","PeriodicalId":19093,"journal":{"name":"Molecular biology, biochemistry, and biophysics","volume":"32 ","pages":"347-67"},"PeriodicalIF":0.0,"publicationDate":"1980-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18052029","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 30
Suicide substrates: mechanism-based inactivators of specific target enzymes. 自杀底物:特定靶酶的基于机制的失活剂。
Molecular biology, biochemistry, and biophysics Pub Date : 1980-01-01 DOI: 10.1007/978-3-642-81503-4_5
C Walsh
{"title":"Suicide substrates: mechanism-based inactivators of specific target enzymes.","authors":"C Walsh","doi":"10.1007/978-3-642-81503-4_5","DOIUrl":"https://doi.org/10.1007/978-3-642-81503-4_5","url":null,"abstract":"","PeriodicalId":19093,"journal":{"name":"Molecular biology, biochemistry, and biophysics","volume":"32 ","pages":"62-77"},"PeriodicalIF":0.0,"publicationDate":"1980-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18453891","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 5
Subunit interaction of adenylylated glutamine synthetase. 腺苷化谷氨酰胺合成酶的亚基相互作用。
Molecular biology, biochemistry, and biophysics Pub Date : 1980-01-01 DOI: 10.1007/978-3-642-81503-4_11
E R Stadtman, R J Hohman, J N Davis, M Wittenberger, P B Chock, S G Rhee
{"title":"Subunit interaction of adenylylated glutamine synthetase.","authors":"E R Stadtman,&nbsp;R J Hohman,&nbsp;J N Davis,&nbsp;M Wittenberger,&nbsp;P B Chock,&nbsp;S G Rhee","doi":"10.1007/978-3-642-81503-4_11","DOIUrl":"https://doi.org/10.1007/978-3-642-81503-4_11","url":null,"abstract":"<p><p>The glutamine synthetase (GS) activity in Escherichia coli is regulated by a bicyclic interconvertible enzyme cascade which involves the cyclic adenylylation (inactivation) and deadenylylation (activation) of GS on the one hand, and the modulation of these processes by the uridylylation and deuridylylation of Shapiro's regulatory protein on the other. The specific activity of GS in a given metabolic state is determined by the fraction of its subunits that are adenylylated, and this fraction is determined by the concentration of over 40 metabolites. Through allosteric and substrate interactions with one or more of the cascade enzymes, these metabolites alter the rates of the covalent modification and demodification reactions. By means of immunoprecipitation studies with anti-AMP specific antibodies, it has been established that the partially adenylylated glutamine synthetase, which is present in a given steady state, is a mixture of hybrid molecules containing different numbers and possibly distributions of adenylylated subunits. Partial separation of these hybrid mixtures has been achieved by affinity chromatography on Affi-Blue Sepharose columns. From immunochemical studies it is evident that anti-AMP antibodies can react with adenylylated subunits of all molecular species of GS, but that the capacities of these primary antigen-antibody reactions to yield precipitable aggregates is very dependent of the number of adenylylated subunits per molecule, and much less so upon the total concentration of adenylylated subunits present. the studies suggest that precipitability is a function either of the distribution of adenylylated subunits within hybrid species, or of the kinetics of intra- vs intermolecular bivalent interactions.</p>","PeriodicalId":19093,"journal":{"name":"Molecular biology, biochemistry, and biophysics","volume":"32 ","pages":"144-56"},"PeriodicalIF":0.0,"publicationDate":"1980-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17175508","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 6
Molecular biology biochemistry and biophysics. 分子生物学，生物化学和生物物理学。
Molecular biology, biochemistry, and biophysics Pub Date : 1980-01-01
{"title":"Molecular biology biochemistry and biophysics.","authors":"","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":19093,"journal":{"name":"Molecular biology, biochemistry, and biophysics","volume":"32 ","pages":"1-430"},"PeriodicalIF":0.0,"publicationDate":"1980-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18453006","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Molecular biology, culture, and society. 分子生物学，文化和社会。
Molecular biology, biochemistry, and biophysics Pub Date : 1980-01-01 DOI: 10.1007/978-3-642-81503-4_30
R Monro
{"title":"Molecular biology, culture, and society.","authors":"R Monro","doi":"10.1007/978-3-642-81503-4_30","DOIUrl":"https://doi.org/10.1007/978-3-642-81503-4_30","url":null,"abstract":"","PeriodicalId":19093,"journal":{"name":"Molecular biology, biochemistry, and biophysics","volume":"32 ","pages":"401-14"},"PeriodicalIF":0.0,"publicationDate":"1980-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18453889","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Effect of catabolite repression on chemotaxis in Salmonella typhimurium. 抑制分解代谢物对鼠伤寒沙门菌趋化性的影响。
Molecular biology, biochemistry, and biophysics Pub Date : 1980-01-01 DOI: 10.1007/978-3-642-81503-4_10
D E Koshland, M J Anderson
{"title":"Effect of catabolite repression on chemotaxis in Salmonella typhimurium.","authors":"D E Koshland,&nbsp;M J Anderson","doi":"10.1007/978-3-642-81503-4_10","DOIUrl":"https://doi.org/10.1007/978-3-642-81503-4_10","url":null,"abstract":"<p><p>The chemotaxis of Salmonella typhimurium LT2-ST1, grown with different sole carbon sources toward ribose, allose, serine, aspartate, and glucose, was examined. Maximum chemotaxis toward serine, aspartate, and glucose were unchanged with either glucose or citrate as the carbon source. The height of the peak in the ribose response curve was 25% of a standard serine response when the bacteria were grown on citrate. However, when the bacteria were grown on glucose, the ribose response was 1% of the serine standard, and when on glycerol, 5%. Chemotaxis toward allose, a competitive inhibitor of ribose chemotaxis, was similarly affected. The amount of ribose binding protein, the receptor for ribose chemotaxis, was determined in bacteria grown on citrate, glucose, or glycerol. The amount of ribose-binding protein released from cells grown on glucose or glycerol was appreciably less than the amount released from cells grown on citrate. These data suggest that the observed effect on ribose chemotaxis is due to catabolite repression of ribose-binding protein and another component of the chemotactic system.</p>","PeriodicalId":19093,"journal":{"name":"Molecular biology, biochemistry, and biophysics","volume":"32 ","pages":"136-43"},"PeriodicalIF":0.0,"publicationDate":"1980-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17830823","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
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